PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus D1007.5a npp-20 14704431 biogrid,i2d,mint,intact,dip exp F13B9.1a npp-20 19123269 intact exp G spk-1 npp-20 18692475,unassigned701 biogrid,mint,intact exp G F49E10.4a npp-20 18692475,unassigned701 biogrid,intact exp G csn-5 npp-20 18692475,unassigned701 biogrid,mint,intact exp G npp-20 Y11D7A.12a 18692475,unassigned701 biogrid,mint,intact exp T08G5.5b npp-20 18692475,unassigned701 biogrid,mint,intact exp G sec-16 npp-20 18692475,unassigned701,19123269 biogrid,mint,intact exp G T01G9.4 npp-20 ortho G rab8 npp-20 ortho G F47G9.1 npp-20 ortho G F55A4.1 npp-20 ortho G Adenylate kinase isoenzyme 6 homolog, AK6 npp-20 ortho G Calcium-transporting ATPase npp-20 ortho G Probable coatomer subunit gamma npp-20 ortho G F45G2.6, TRF-1 npp-20 ortho Y25C1A.7c npp-20 ortho G npp-20 C39F7.4 ortho G seld-1 npp-20 ortho ldh-1 npp-20 ortho G Y38F2AL.2 npp-20 ortho npp-20 Y116A8C.12 ortho G npp-20 Putative U5 small nuclear ribonucleoprotein 200 kDa helicase ortho G npp-20 mys-1 ortho G cul-3 npp-20 ortho G Probable succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial npp-20 ortho G F53G12.1 npp-20 ortho G rpn-11 npp-20 ortho G chc-1 npp-20 ortho G npp-20 npp-20 ortho G F10E7.4 npp-20 ortho G fln-1 npp-20 ortho G Nicotinate phosphoribosyltransferase, NAPRTase npp-20 ortho npp-20 F23C8.6 ortho G D1014.3 npp-20 ortho G ZC518.2 npp-20 ortho G srs-2 npp-20 ortho G gos-28 npp-20 ortho pbs-6 npp-20 ortho G dhhc-6 npp-20 ortho G npp-20 Y46G5A.12 ortho G npp-18 npp-20 ortho C01G10.8 npp-20 ortho G F29G9.3 npp-20 ortho G eif-6 npp-20 ortho G sel-9 npp-20 ortho G ZK742.1a npp-20 ortho G npp-20 Y113G7A.3 ortho G ZK795.1 npp-20 ortho Probable electron transfer flavoprotein subunit alpha, mitochondrial, Alpha-ETF npp-20 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9N4A7 O01870 - 14704431 - X 2 Q9N4A7 O01870 two hybrid 14704431 physical association X 2 Q9N4A7 O01870 two hybrid pooling approach 14704431 physical association X 2 Q9N4A7 P91001 two hybrid - physical association X 2 P34643 Q9N4A7 two hybrid pooling approach 19123269 physical association X 2 P34643 Q9N4A7 two hybrid array 19123269 physical association X 2 P34643 Q9N4A7 two hybrid - physical association X 2 H2L061 Q9N4A7 two hybrid - physical association X 2 H2KZQ8 Q9N4A7 two hybrid pooling approach 19123269 physical association X 2 H2KZQ8 Q9N4A7 two hybrid array 19123269 physical association X 2 Q9N4A7 Q9XUQ4 two hybrid - physical association X 2 Q03563 Q9N4A7 two hybrid - physical association X 2 Q9XWR1 Q9N4A7 two hybrid - physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B npp-20 flh-1 MI:0018(two hybrid)|MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_24553|MINT_6257 null|bait prey|prey npp-20 flh-1 MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_28827 bait prey ZK512.5 npp-20 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 18692475,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(biogrid)|(intact) MINT_6251|MINT_6253|MINT_6252|UniProt_21616|UniProt_24851|BIOGRID_28828|UniProt_19707 prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|null|bait|bait npp-20 vps-39 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(intact) MINT_6250|MINT_6258|UniProt_24679 bait|bait|null prey|prey|prey npp-20 F49E10.4 MI:0018(two hybrid) pubmed:unassigned701 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24925 null prey spk-1 npp-20 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint) UniProt_25211|BIOGRID_28823|MINT_6254 prey|prey|null null|bait|bait CELE_F49E10.4 npp-20 MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_28825 prey bait D1007.5 npp-20 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(intact)|MI:0471(mint) DIP_1741|UniProt_30124|MINT_7373 -|bait|bait -|prey|prey Q20597 npp-20 MI:0018(two hybrid) 18692475 taxid:0() taxid:6239(Caenorhabditis elegans) MI:0915(physical association) MI:0471(mint) MINT_6256 prey bait npp-20 CELE_D1007.5 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_22068 prey bait npp-20 CELE_F13B9.1 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_18682|UniProt_20596 bait|bait prey|prey csn-5 npp-20 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint) UniProt_25014|BIOGRID_28824|MINT_6255 prey|prey|prey null|bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9N4A7 Q1ZXS5 NPP-20 VPS-39 0.183 18692475 Q9N4A7 P91001 NPP-20 CSN-5 0.454 unassigned701,18692475 Q9XUQ4 Q9N4A7 VPS-39 NPP-20 0.183 unassigned701 Q9XWR1 Q9N4A7 FLH-1 NPP-20 0.332 unassigned701,18692475 Q9N4A7 H2KZQ8 NPP-20 H2KZQ8 0.236 19123269 Q9N4A7 Q03563 NPP-20 SPK-1 0.454 unassigned701,18692475 Q9N4A7 P34643 NPP-20 SEC-16 0.583 19123269,unassigned701,18692475 Q9N4A7 H2L061 NPP-20 H2L061 0.183 unassigned701 Q9N4A7 Q20597 NPP-20 Q20597 0.183 18692475 Q9N4A7 O01870 NPP-20 O01870 0.155 14704431