PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Non-specific protein-tyrosine kinase Y63D3A.5 23549480 intact exp Eyes absent homolog Y63D3A.5 14704431 biogrid,i2d,mint,intact,dip exp C12D8.1b Y63D3A.5 14704431 biogrid,i2d,mint,intact,dip exp vav-1 Y63D3A.5 23549480 intact exp Y53C12B.3b Y63D3A.5 19123269 intact exp K09B11.9a Y63D3A.5 14704431 biogrid,intact exp Y55B1BR.4 Y63D3A.5 21110867 intact exp Y63D3A.5 Y116A8C.36a 23549480 intact exp bar-1 Y63D3A.5 unassigned1274 intact exp Dicer-related helicase, F15B10.2a Y63D3A.5 16439208 intact exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9U1W1 - 14704431 - X 2 Q17935 Q9U1W1 - 14704431 - X 2 Q9U1W1 Q564S5 - 14704431 - X 2 Q9U1W1 G5EGG0 two hybrid 14704431 direct interaction X 2 Q9U1W1 Q2XMZ9 two hybrid 14704431 direct interaction X 2 Q9U1W1 Q564S5 two hybrid 14704431 direct interaction X 2 Q9U1W1 two hybrid 14704431 physical association X 2 Q17935 Q9U1W1 two hybrid 14704431 physical association X 2 Q9U1W1 Q564S5 two hybrid 14704431 physical association X 2 O17670 Q9U1W1 two hybrid pooling approach 14704431 physical association X 2 Q45FX5 Q9U1W1 two hybrid 23549480 physical association X 2 Q95XW5 Q9U1W1 two hybrid pooling approach 21110867 physical association X 2 O18218 Q9U1W1 two hybrid pooling approach 19123269 physical association X 2 Q17936 Q9U1W1 two hybrid pooling approach 14704431 physical association X 2 Q9U1W1 G5EGG0 two hybrid pooling approach 14704431 physical association X 2 Q9U1W1 Q9U2T9 two hybrid 23549480 physical association X 2 Q9U1W1 Q9U2T9 two hybrid 23549480 physical association X 2 O62486 Q9U1W1 two hybrid array 19123269 physical association X 2 G5EE56 Q9U1W1 two hybrid 23549480 physical association X 2 G5EE56 Q9U1W1 two hybrid 23549480 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B eya-1 tfg-1 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_30077|MINT_7297|DIP_1694 bait|bait|- prey|prey|- vav-1 tfg-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23558 bait prey tfg-1 itsn-1 MI:0018(two hybrid)|MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_23449|UniProt_23476 prey|prey bait|bait eya-1 tfg-1 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_21983 bait prey C12D8.1 tfg-1 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) MI:0465(dip) DIP_1327 - - tfg-1 uso-1 MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_31283 prey bait magu-1 tfg-1 MI:0398(two hybrid pooling approach) 21110867 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_22149 bait prey tfg-1 Q9XU77 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0465(dip) MINT_1332|DIP_2895 prey|- bait|- tfg-1 src-1 MI:0018(two hybrid)|MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_23945|UniProt_24445 prey|prey bait|bait C12D8.1 tfg-1 MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact) MINT_6873|UniProt_29709 bait|bait prey|prey nos-3 tfg-1 MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_19670 bait prey nos-3 tfg-1 MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_21586 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9U1W1 Q18825 TFG-1 BAR-1 0.183 26780296 Q9U1W1 O62486 TFG-1 NOS-3 0.126 19123269 Q9XU77 Q9U1W1 Q9XU77 TFG-1 0.033 14704431 Q9U1W1 O17670 TFG-1 EYA-1 0.155 14704431 Q9U1W1 G5EE56 TFG-1 SRC-1 0.183 23549480 Q9U1W1 G5EGG0 TFG-1 USO-1 0.126 14704431 Q9U1W1 O18218 TFG-1 NOS-3 0.126 19123269 Q9U1W1 Q17935 TFG-1 Q17935 0.033 14704431 Q9U1W1 Q17936 TFG-1 Q17936 0.126 14704431 Q9U1W1 Q95XW5 TFG-1 MAGU-1 0.126 21110867 Q9U2T9 Q9U1W1 ITSN-1 TFG-1 0.332 23549480 Q9U1W1 G5EDI8 TFG-1 DRH-1 0.126 16439208 Q9U1W1 Q45FX5 TFG-1 VAV-1 0.183 23549480