PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ubc-1 Y54G2A.31 11778048,14704431 biogrid,i2d,mint,intact exp G T24D1.3 Y54G2A.31 i2d exp nhl-1 Y54G2A.31 i2d exp C53A5.6b Y54G2A.31 19123269 i2d,intact exp Y54G2A.31 Y71F9AL.10 i2d exp G F39B2.2 Y54G2A.31 11778048,21179194,14704431 biogrid,i2d,mint,intact exp, ortho G ufd-1 Y54G2A.31 ortho G fzo-1 Y54G2A.31 ortho G hipr-1 Y54G2A.31 ortho G D1081.8 Y54G2A.31 ortho G peli-1 Y54G2A.31 ortho G Y54G2A.31 R13A5.9 ortho G C07G1.5 Y54G2A.31 ortho G Y54G2A.31 K08E3.7a ortho G Uncharacterized protein T27F2.1 Y54G2A.31 ortho G Y54G2A.31 siah-1 ortho G ubl-5 Y54G2A.31 ortho G C01G6.4 Y54G2A.31 ortho G fum-1 Y54G2A.31 ortho G air-2 Y54G2A.31 ortho arx-2 Y54G2A.31 ortho G idha-1 Y54G2A.31 ortho G ZK20.3 Y54G2A.31 ortho G Y54G2A.31 dcn-1 ortho usp-14 Y54G2A.31 ortho G C56C10.1 Y54G2A.31 ortho G C31C9.2 Y54G2A.31 ortho G Probable protein ariadne-2, Ari-2 Y54G2A.31 ortho G got-1.2 Y54G2A.31 ortho G Y54G2A.31 Protein IMPACT homolog ortho F22D3.6, Paracaspase Y54G2A.31 ortho G Y92H12A.2a Y54G2A.31 ortho G arc-1 Y54G2A.31 ortho G pyc-1 Y54G2A.31 ortho G C47E12.5a Y54G2A.31 ortho G F17C8.9 Y54G2A.31 ortho vha-15 Y54G2A.31 ortho G Y54G2A.31 C18B12.4 ortho G cyn-1 Y54G2A.31 ortho G K07A12.4a Y54G2A.31 ortho G Y54G2A.31 W03A5.7 ortho riok-3 Y54G2A.31 ortho G F53H1.3a Y54G2A.31 ortho G 1G758 Y54G2A.31 ortho G F52E4.1a Y54G2A.31 ortho G C18F10.7a Y54G2A.31 ortho G atx-3 Y54G2A.31 ortho Putative esterase F42H10.6 Y54G2A.31 ortho G nfx-1 Y54G2A.31 ortho G pcca-1 Y54G2A.31 ortho G hrdl-1 Y54G2A.31 ortho G Y54G2A.31 Y54G2A.31 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P52478 Q95XX0 - 12679813 - X 2 P52478 Q95XX0 - 11778048 - X 2 Q95XX0 - 12679813 - X 2 Q95XX0 Q03601 - 15530417 - X 2 O45495 Q95XX0 - 11778048 - X 2 O45495 Q95XX0 - 12679813 - X 2 O02333 Q95XX0 - 12679813 - X 2 Q95XX0 - 12679813 - X 2 O17698 Q95XX0 - 12679813 - X 2 P52478 Q95XX0 two hybrid 14704431 direct interaction X 2 O45495 Q95XX0 two hybrid 14704431 direct interaction X 2 O45495 Q95XX0 affinity chromatography technology 21179194 physical association X 2 O45495 Q95XX0 two hybrid 21179194 direct interaction X 2 O45495 Q95XX0 two hybrid 21179194 direct interaction X 2 P52478 Q95XX0 two hybrid pooling approach 11778048 physical association X 2 O45495 Q95XX0 two hybrid pooling approach 11778048 physical association X 2 O45495 Q95XX0 two hybrid pooling approach 11778048 physical association X 2 O17698 Q95XX0 two hybrid pooling approach 19123269 physical association X 2 O17698 Q95XX0 two hybrid array 19123269 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q95XX0 O17698 UBC-13 O17698 0.236 19123269 Q95XX0 O45495 UBC-13 UEV-1 0.765 11778048,21179194,14704431 Q95XX0 P52478 UBC-13 UBC-1 0.286 14704431,11778048