PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus F39B2.2 nhr-91 11778048,14704431 biogrid,i2d,mint,intact exp C32F10.2, Synthetic multivulva protein LIN-35 Rb F39B2.2 11778048,14704431 biogrid,intact exp G F39B2.2 B0432.8 11778048,14704431 biogrid,i2d,mint,intact exp F39B2.2 K08E3.5b 11778048,14704431 biogrid,i2d,mint,intact exp G F39B2.2 eef-2 11778048,14704431 biogrid,i2d,mint,intact exp G K12D12.5 F39B2.2 11778048,14704431 biogrid,intact exp F39B2.2 Nucleoside diphosphate kinase 11778048,14704431 biogrid,i2d,mint,intact exp, ortho G F39B2.2 Y54G2A.31 11778048,21179194,14704431 biogrid,i2d,mint,intact exp, ortho G F39B2.2 hipr-1 ortho G F39B2.2 ufd-2 ortho F39B2.2 rnf-5 ortho G 1G758 F39B2.2 ortho G F39B2.2 C01G6.4 ortho G F39B2.2 K08E3.7a ortho G F39B2.2 ech-6 ortho G F39B2.2 C47E12.5a ortho G F39B2.2 Protein IMPACT homolog ortho F39B2.2 vha-10 ortho G F39B2.2 riok-3 ortho G F39B2.2 C07G1.5 ortho G F39B2.2 C18F10.7a ortho G F39B2.2 B0361.10 ortho G ten-1 F39B2.2 ortho G F39B2.2 C30H7.2b ortho G F39B2.2 vha-9 ortho G F39B2.2 peli-1 ortho G atx-3 F39B2.2 ortho F39B2.2 hint-1 ortho G F39B2.2 dcn-1 ortho F39B2.2 W03A5.7 ortho F39B2.2 sqv-4 ortho G F39B2.2 hap-1 ortho G chp F39B2.2 ortho G F39B2.2 ubc-1 ortho G F39B2.2 arc-1 ortho G F39B2.2 Y110A7A.12 ortho tag-335 F39B2.2 ortho G F39B2.2 R13A5.9 ortho G F39B2.2 Probable protein ariadne-2, Ari-2 ortho G F39B2.2 let-70 ortho G F53H1.3a F39B2.2 ortho G F39B2.2 pbs-6 ortho G F39B2.2 cyn-1 ortho G F39B2.2 gspd-1 ortho G F39B2.2 Peptidyl-prolyl cis-trans isomerase ortho G F39B2.2 K07A12.4a ortho G F14F3.1a, Variable abnormal-3 F39B2.2 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O45495 P29691 - 11778048 - X 2 O45495 P29691 - 12679813 - X 2 O45495 Q95XX0 - 11778048 - X 2 O45495 Q95XX0 - 12679813 - X 2 Q9XUS4 O45495 - 11778048 - X 2 Q9XUS4 O45495 - 12679813 - X 2 O45495 - 11778048 - X 2 O45495 - 12679813 - X 2 O45495 G5ED63 - 11778048 - X 2 O45495 G5ED63 - 12679813 - X 2 O45495 Q93576 - 12679813 - X 2 O45495 Q93576 - 11778048 - X 2 O45495 Q9U2R6 - 12679813 - X 2 O45495 Q9U2R6 - 11778048 - X 2 O45495 G5EDT1 - 11778048 - X 2 O45495 G5EDT1 - 12679813 - X 2 O45495 P90989 two hybrid 14704431 direct interaction X 2 O45495 P29691 two hybrid 14704431 direct interaction X 2 O45495 Q69Z13 two hybrid 14704431 direct interaction X 2 O45495 Q9U2R6-2 two hybrid 14704431 direct interaction X 2 O45495 Q95XX0 two hybrid 14704431 direct interaction X 2 O45495 Q95XX0 affinity chromatography technology 21179194 physical association X 2 O45495 Q95XX0 two hybrid 21179194 direct interaction X 2 O45495 Q95XX0 two hybrid 21179194 direct interaction X 2 O45495 G5EDT1 two hybrid 14704431 direct interaction X 2 O45495 Q93576 two hybrid 14704431 direct interaction X 2 O45495 G5ED63 two hybrid 14704431 direct interaction X 2 O45495 P90989 two hybrid pooling approach 11778048 physical association X 2 O45495 P29691 two hybrid pooling approach 11778048 physical association X 2 O45495 Q95XX0 two hybrid pooling approach 11778048 physical association X 2 O45495 Q95XX0 two hybrid pooling approach 11778048 physical association X 2 Q9XUS5 O45495 two hybrid pooling approach 11778048 physical association X 2 O45495 G5EDT1 two hybrid pooling approach 11778048 physical association X 2 O45495 Q93576 two hybrid pooling approach 11778048 physical association X 2 O45495 G5ED63 two hybrid pooling approach 11778048 physical association X 2 O45495 Q9U2R6 two hybrid pooling approach 11778048 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B uev-1 B0432.8 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(intact)|MI:0471(mint) 113712|BIOGRID_22649|UniProt_1366|MINT_599 bait|bait|bait|bait prey|prey|prey|prey uev-1 nhr-91 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 11778048,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|MI:0471(mint)|(biogrid) UniProt_1372|113730|MINT_605|BIOGRID_22655 bait|bait|bait|bait prey|prey|prey|prey uev-1 ubc-13 MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 11778048,14704431,21179194 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|MI:0471(mint)|(intact)|(intact)|(intact)|MI:0471(mint)|(biogrid)|(biogrid) BIOGRID_22656|BIOGRID_28285|UniProt_1373|MINT_606|113952|113733|UniProt_1446|MINT_3143|BIOGRID_28284|BIOGRID_28283 bait|bait|bait|bait|prey|bait|prey|prey|prey|prey prey|prey|prey|prey|bait|prey|bait|bait|bait|bait uev-1 K08E3.5 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|(intact) MINT_603|UniProt_1370|113724 bait|bait|bait prey|prey|prey O01682 uev-1 MI:0398(two hybrid pooling approach) 11778048 taxid:0() taxid:6239(Caenorhabditis elegans) MI:0915(physical association) MI:0471(mint) MINT_600 prey bait uev-1 eef-2 MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|MI:0471(mint)|(intact) 113721|BIOGRID_22652|MINT_602|UniProt_1369 bait|bait|bait|bait prey|prey|prey|prey uev-1 Q21439 MI:0398(two hybrid pooling approach) 11778048 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_604 bait prey uev-1 ndk-1 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|(intact) BIOGRID_22651|MINT_601|UniProt_1368|113718 bait|bait|bait|bait prey|prey|prey|prey uev-1 K08E3.5 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_22653 bait prey uev-1 lin-35 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_22650|UniProt_1367|113715 bait|bait|bait prey|prey|prey uev-1 K12D12.5 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 11778048,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_22654|113727|UniProt_1371 bait|bait|bait prey|prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9XUS5 O45495 Q9XUS5 UEV-1 0.126 11778048 Q95XX0 O45495 UBC-13 UEV-1 0.765 11778048,21179194,14704431 P29691 O45495 EEF-2 UEV-1 0.286 14704431,11778048 Q93576 O45495 NDK-1 UEV-1 0.126 11778048 Q9U2R6 O45495 NHR-91 UEV-1 0.286 14704431,11778048 P90989 O45495 P90989 UEV-1 0.126 11778048 O45495 G5ED63 UEV-1 G5ED63 0.126 11778048 O45495 G5EDT1 UEV-1 LIN-35 0.126 11778048