PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus mctp-1 wdfy-2 14704431 biogrid exp wdfy-2 Receptor expression-enhancing protein 14704431 biogrid,i2d,mint,intact,dip exp G wdfy-2 acl-9 14704431 biogrid,i2d,mint,intact,dip exp G wdfy-2 Y38C1AA.7 14704431 biogrid,i2d,mint,intact,dip exp Uncharacterized protein C06E1.1 wdfy-2 19123269,14704431 biogrid,i2d,mint,intact,dip exp wdfy-2 F56A8.3a 14704431 biogrid,i2d,mint,intact,dip exp G F17E9.5 wdfy-2 14704431 i2d,mint,intact,dip exp D2096.2a wdfy-2 19123269,14704431 biogrid,intact exp G wdfy-2 C05D9.1 14704431 biogrid,i2d,mint,intact,dip exp G Reticulon-like protein wdfy-2 19123269,14704431 biogrid,mint,intact,dip exp G wdfy-2 Y43C5A.6a 19123269 intact exp wdfy-2 F35G12.9 14704431 biogrid,i2d,mint,intact,dip exp G Major sperm protein wdfy-2 14704431 biogrid,i2d,mint,intact,dip exp G wdfy-2 ZK822.4 14704431 biogrid,i2d,mint,intact,dip exp G Uncharacterized protein F13E6.1 wdfy-2 14704431 biogrid,i2d,mint,intact exp G ZC477.3a wdfy-2 ortho G wdfy-2 F58B3.7 ortho G F53A2.4, NUD-1 wdfy-2 ortho G wdfy-2 C07H6.4 ortho G Probable glycerol-3-phosphate dehydrogenase, mitochondrial, GPD-M, GPDH-M wdfy-2 ortho G C14A4.2 wdfy-2 ortho G wdfy-2 F09E5.17 ortho G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9GYJ9 Q18964 - 14704431 - X 2 Q18964 - 14704431 - X 2 Q95ZS5 Q18964 - 14704431 - X 2 Q18964 Q18503 - 14704431 - X 2 Q9N431 Q18964 - 14704431 - X 2 Q9N4G8 Q18964 - 14704431 - X 2 Q18964 - 14704431 - X 2 Q18964 - 14704431 - X 2 Q18964 P34296 - 14704431 - X 2 Q18964 Q23087 - 14704431 - X 2 Q18964 P55326 - 14704431 - X 2 Q18964 H2KZJ7 - 14704431 - X 2 Q20052 Q18964 - 14704431 - X 2 Q23615 Q18964 - 14704431 - X 2 Q9GYJ9 Q18964 two hybrid 14704431 direct interaction X 2 Q95ZS5 Q18964 two hybrid 14704431 direct interaction X 2 Q18964 Q18503 two hybrid 14704431 direct interaction X 2 Q18964 H2KZJ6 two hybrid 14704431 direct interaction X 2 Q9N431 Q18964 two hybrid 14704431 direct interaction X 2 Q9N4G8 Q18964 two hybrid 14704431 direct interaction X 2 Q18964 two hybrid 14704431 direct interaction X 2 Q18964 P34296 two hybrid 14704431 direct interaction X 2 Q18964 H2KZJ7 two hybrid 14704431 direct interaction X 2 Q18964 P55326 two hybrid 14704431 direct interaction X 2 Q18964 G5ECZ2 two hybrid 14704431 direct interaction X 2 Q18964 Q23087 two hybrid 14704431 direct interaction X 2 Q20052 Q18964 two hybrid 14704431 direct interaction X 2 Q23615 Q18964 two hybrid 14704431 direct interaction X 2 Q9GYJ9 Q18964 two hybrid 14704431 physical association X 2 Q95ZS5 Q18964 two hybrid 14704431 physical association X 2 Q18964 Q18503 two hybrid 14704431 physical association X 2 Q18964 H2KZJ6 two hybrid 14704431 physical association X 2 Q18964 Q23187 two hybrid 14704431 physical association X 2 Q9N431 Q18964 two hybrid 14704431 physical association X 2 Q9N4G8 Q18964 two hybrid 14704431 physical association X 2 Q18964 two hybrid 14704431 physical association X 2 Q18964 P34296 two hybrid 14704431 physical association X 2 Q18964 H2KZJ7 two hybrid 14704431 physical association X 2 Q18964 P55326 two hybrid 14704431 physical association X 2 Q18964 Q23087 two hybrid 14704431 physical association X 2 Q20052 Q18964 two hybrid 14704431 physical association X 2 Q23615 Q18964 two hybrid 14704431 physical association X 2 Q9GYJ9 Q18964 two hybrid pooling approach 14704431 physical association X 2 Q9GYJ9 Q18964 two hybrid pooling approach 14704431 physical association X 2 Q95ZS5 Q18964 two hybrid pooling approach 14704431 physical association X 2 G5EDI2 Q18964 two hybrid pooling approach 19123269 physical association X 2 G5EDI2 Q18964 two hybrid array 19123269 physical association X 2 Q18964 Q18503 two hybrid pooling approach 14704431 physical association X 2 Q18964 Q23187 two hybrid pooling approach 14704431 physical association X 2 Q95Q25 Q18964 two hybrid pooling approach 19123269 physical association X 2 Q95Q25 Q18964 two hybrid array 19123269 physical association X 2 Q9N431 Q18964 two hybrid pooling approach 14704431 physical association X 2 Q9N4G8 Q18964 two hybrid pooling approach 14704431 physical association X 2 Q18964 P34296 two hybrid pooling approach 14704431 physical association X 2 Q18964 H2KZJ7 two hybrid pooling approach 14704431 physical association X 2 Q18964 P55326 two hybrid pooling approach 14704431 physical association X 2 Q18964 Q23087 two hybrid pooling approach 14704431 physical association X 2 Q18964 H2KZJ7 two hybrid pooling approach 19123269 physical association X 2 Q18964 P34296 two hybrid pooling approach 19123269 physical association X 2 Q18964 H2KZJ7 two hybrid array 19123269 physical association X 2 Q18964 P34296 two hybrid array 19123269 physical association X 2 O61521 Q18964 two hybrid pooling approach 14704431 physical association X 2 Q20052 Q18964 two hybrid pooling approach 14704431 physical association X 2 Q23615 Q18964 two hybrid pooling approach 14704431 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B wdfy-2 F56A8.3 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_30181|MINT_50|DIP_1797 bait|bait|- prey|prey|- P91199 wdfy-2 MI:0018(two hybrid) 14704431 taxid:0() taxid:6239(Caenorhabditis elegans) MI:0915(physical association) MI:0465(dip) DIP_1793 - - wdfy-2 acl-9 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0465(dip) UniProt_30185|MINT_54|BIOGRID_22131|DIP_1801 bait|bait|bait|- prey|prey|prey|- wdfy-2 yop-1 MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|MI:0465(dip)|MI:0471(mint) UniProt_30183|BIOGRID_22130|DIP_1800|MINT_53 bait|bait|-|bait prey|prey|-|prey wdfy-2 Q95Q59 MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact) MINT_46|UniProt_30177 bait|bait prey|prey wdfy-2 rad-51 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_20454|UniProt_18542 bait|bait prey|prey wdfy-2 Y38C1AA.7 MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip)|MI:0471(mint) BIOGRID_22129|UniProt_30184|DIP_1799|MINT_52 bait|bait|-|bait prey|prey|-|prey wdfy-2 Q19008 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint) DIP_1794|MINT_47 -|bait -|prey C06E1.1 wdfy-2 MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 14704431,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|MI:0465(dip)|MI:0471(mint) UniProt_19978|UniProt_30175|UniProt_18065|BIOGRID_22121|DIP_1791|MINT_44 prey|prey|prey|prey|-|prey bait|bait|bait|bait|-|bait C36H8.1 wdfy-2 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_1792|MINT_45|BIOGRID_22122|UniProt_30176 -|prey|prey|prey -|bait|bait|bait wdfy-2 praf-3 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_20453|UniProt_18537|UniProt_30178 bait|bait|bait prey|prey|prey wdfy-2 praf-3 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_22124 bait prey wdfy-2 ZK822.4 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0465(dip) BIOGRID_22132|MINT_55|UniProt_30186|DIP_1802 bait|bait|bait|- prey|prey|prey|- F13E6.1 wdfy-2 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0465(dip)|MI:0471(mint)|(biogrid)|(intact) DIP_1795|MINT_48|BIOGRID_22125|UniProt_30179 -|prey|prey|prey -|bait|bait|bait wdfy-2 apc-11 MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|(intact)|(biogrid)|MI:0465(dip) MINT_527|UniProt_30604|BIOGRID_22581|DIP_2221 prey|prey|prey|- bait|bait|bait|- wdfy-2 ret-1 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip) UniProt_30182|MINT_51|DIP_1798 bait|bait|- prey|prey|- wdfy-2 ret-1 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 14704431,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact) BIOGRID_22128|UniProt_20455|UniProt_18538 bait|bait|bait prey|prey|prey F17E9.5 wdfy-2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|MI:0471(mint)|(intact) DIP_1796|BIOGRID_22126|MINT_49|UniProt_30180 -|prey|prey|prey -|bait|bait|bait wdfy-2 snx-1 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint)|MI:0465(dip)|(biogrid)|MI:0471(mint)|(intact) UniProt_29618|MINT_6769|DIP_1233|BIOGRID_21452|MINT_43|UniProt_30174 prey|prey|-|prey|bait|bait bait|bait|-|bait|prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q18964 Q18503 WDFY-2 Q18503 0.155 14704431 Q23187 Q18964 RET-1 WDFY-2 0.155 14704431 Q18964 O61521 WDFY-2 O61521 0.155 14704431 Q19008 Q18964 Q19008 WDFY-2 0.033 14704431 Q18964 P34296 WDFY-2 P34296 0.472 19123269,14704431 Q23615 Q18964 Q23615 WDFY-2 0.155 14704431 Q9N431 Q18964 Q9N431 WDFY-2 0.155 14704431 Q20052 Q18964 APC-11 WDFY-2 0.309 14704431 Q9GYJ9 Q18964 SNX-1 WDFY-2 0.261 14704431 Q9N4G8 Q18964 YOP-1 WDFY-2 0.155 14704431 Q95Q25 Q18964 RAD-51 WDFY-2 0.236 19123269 Q18964 G5EDI2 WDFY-2 RET-1 0.236 19123269 Q23087 Q18964 ACL-9 WDFY-2 0.155 14704431 Q95ZS5 Q18964 Q95ZS5 WDFY-2 0.155 14704431 Q18964 P91199 WDFY-2 P91199 0.033 14704431 Q18964 H2KZJ7 WDFY-2 PRAF-3 0.332 19123269,14704431 Q18964 P55326 WDFY-2 P55326 0.309 14704431