PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Y45F10C.3 wrn-1 11778048,14704431 biogrid,i2d,mint,intact exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O62474 Q19546 - 11778048 - X 2 O62474 Q19546 - 12679813 - X 2 O62474 Q19546 two hybrid 14704431 direct interaction X 2 O62474 Q19546 two hybrid pooling approach 11778048 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B fbxa-215 wrn-1 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach) 11778048,14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) MI:0471(mint)|(intact)|(biogrid)|(intact) MINT_305|UniProt_1355|BIOGRID_22372|113679 prey|prey|prey|prey bait|bait|bait|bait