PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ZK1055.1 bath-42 14704431 biogrid,i2d,mint,intact,dip exp bath-42 C16A3.5 14704431 biogrid,i2d,mint,intact,dip exp G bath-42 cul-3 13679922 biogrid,i2d,mint,intact exp G cye-1 bath-42 18692475,unassigned701 biogrid,mint,intact exp bath-42 pah-1 14704431 biogrid,i2d,mint,intact,dip exp G bath-42 bath-42 12445390,14704431 biogrid,i2d,mint,intact exp G bath-42 W02D9.3 19123269 intact exp F44F1.7 bath-42 19123269 intact exp bath-42 C27B7.4 14704431 biogrid,i2d,mint,intact,dip exp G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P34371 Q17391 - 13679922 - X 2 P34371 P34371 - 12445390 - X 2 Q18036 P34371 - 14704431 - X 2 O76447 P34371 - 14704431 - X 2 P90925 P34371 - 14704431 - X 2 Q18241 P34371 - 14704431 - X 2 P34371 Q17391 two hybrid 13679922 direct interaction X 2 P34371 Q17391 affinity chromatography technology 13679922 physical association X 2 P34371 P34371 two hybrid 12445390 direct interaction X 2 P34371 P34371 two hybrid 14704431 direct interaction X 2 Q18036 P34371 two hybrid 14704431 direct interaction X 2 O76447 P34371 two hybrid 14704431 direct interaction X 2 Q18241 P34371 two hybrid 14704431 direct interaction X 2 P90925 P34371 two hybrid 14704431 direct interaction X 2 P34371 O01501-2 two hybrid 18692475 direct interaction X 2 Q18036 P34371 two hybrid 14704431 physical association X 2 O76447 P34371 two hybrid 14704431 physical association X 2 Q18241 P34371 two hybrid 14704431 physical association X 2 P90925 P34371 two hybrid 14704431 physical association X 2 Q9XVG8 P34371 two hybrid pooling approach 19123269 physical association X 2 Q9XVG8 P34371 two hybrid array 19123269 physical association X 2 P34371 P34371 two hybrid 12445390 physical association X 2 P34371 Q17391 two hybrid 13679922 physical association X 2 P34371 Q17391 pull down 13679922 physical association X 2 P34371 Q17391 two hybrid 13679922 physical association X 2 Q18036 P34371 two hybrid pooling approach 14704431 physical association X 2 O76447 P34371 two hybrid pooling approach 14704431 physical association X 2 Q18241 P34371 two hybrid pooling approach 14704431 physical association X 2 P90925 P34371 two hybrid pooling approach 14704431 physical association X 2 G5EEK5 P34371 two hybrid pooling approach 19123269 physical association X 2 G5EEK5 P34371 two hybrid array 19123269 physical association X 2 O01501 P34371 two hybrid - physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B cye-1 bath-42 MI:0018(two hybrid)|MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_25001|MINT_4279 null|null prey|prey bath-42 rad-26 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0465(dip)|(biogrid) UniProt_30083|MINT_7311|DIP_1700|BIOGRID_21997 bait|bait|-|bait prey|prey|-|prey bath-42 C16A3.5 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|MI:0465(dip) BIOGRID_21589|MINT_6914|UniProt_29733|DIP_1350 prey|prey|prey|- bait|bait|bait|- bath-42 vet-6 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_20379|UniProt_18462 bait|bait prey|prey bath-42 hmg-20 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_20378|UniProt_18460 prey|prey bait|bait hcp-1 bath-42 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0007(anti tag coimmunoprecipitation) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|MI:0471(mint)|(intact) DIP_1702|BIOGRID_22000|MINT_7314|UniProt_30085 -|prey|prey|prey -|bait|bait|bait bath-42 pah-1 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|MI:0471(mint)|(biogrid)|MI:0465(dip) UniProt_30084|MINT_7313|BIOGRID_21999|DIP_1701 bait|bait|bait|- prey|prey|prey|- bath-42 cul-3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 13679922 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(intact)|(intact)|MI:0471(mint) UniProt_356|BIOGRID_28585|BIOGRID_28595|UniProt_350|UniProt_340|MINT_3851 prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9XVG8 P34371 HMG-20 BATH-42 0.236 19123269 P34371 G5EEK5 BATH-42 VET-6 0.236 19123269 P34371 O76447 BATH-42 HCP-1 0.155 14704431 P34371 P34371 BATH-42 BATH-42 0.507 12445390,14704431 P90925 P34371 PAH-1 BATH-42 0.309 14704431 Q17391 P34371 CUL-3 BATH-42 0.702 13679922 Q18036 P34371 Q18036 BATH-42 0.155 14704431 Q18241 P34371 RAD-26 BATH-42 0.155 14704431 P34371 O01501 BATH-42 CYE-1 0.454 unassigned701,18692475