PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus T05H4.2 F36D1.1 19123269 intact exp F46A9.5 T05H4.2 18692475,unassigned701,19123269 biogrid,intact exp F46A9.4, SKR-2 T05H4.2 19123269 intact exp W07B3.2b T05H4.2 19123269,14704431 biogrid,intact exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O16525 H2L0F5 - 14704431 - X 2 O16525 G5ECU1 two hybrid 18692475 direct interaction X 2 O16525 H2L0F8 two hybrid 14704431 direct interaction X 2 O16525 H2L0F5 two hybrid 14704431 physical association X 2 O16525 G5EDD8 two hybrid pooling approach 19123269 physical association X 2 O16525 G5ECU1 two hybrid pooling approach 19123269 physical association X 2 O16525 G5ECU1 two hybrid pooling approach 19123269 physical association X 2 O16525 G5EDD8 two hybrid array 19123269 physical association X 2 O16525 G5ECU1 two hybrid array 19123269 physical association X 2 O16525 G5ECU1 two hybrid array 19123269 physical association X 2 O16525 G5ECU1 two hybrid - physical association X 2 O16525 H2L0F6 two hybrid pooling approach 14704431 physical association X 2 O16525 Q9XV35 two hybrid pooling approach 19123269 physical association X 2 O16525 H2L0F6 two hybrid pooling approach 19123269 physical association X 2 O16525 Q9XV35 two hybrid array 19123269 physical association X 2 O16525 H2L0F6 two hybrid array 19123269 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B fbxa-196 madf-2 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_18881|UniProt_20792 bait|bait prey|prey fbxa-196 gei-4 MI:0007(anti tag coimmunoprecipitation)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 14704431,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_28533|UniProt_19475|UniProt_21388 prey|bait|bait bait|prey|prey fbxa-196 gei-4 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0407(direct interaction) (biogrid) BIOGRID_24653 prey bait fbxa-196 Q9TZ39 MI:0018(two hybrid) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association) MI:0465(dip) DIP_4141 - - fbxa-196 Q9TZ38 MI:0398(two hybrid pooling approach) 14704431 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_2655 prey bait fbxa-196 skr-1 MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach)|MI:0018(two hybrid)|MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 18692475,19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_25273|UniProt_20907|UniProt_20908|BIOGRID_29183|UniProt_18996|UniProt_18995 prey|prey|bait|prey|prey|bait bait|bait|prey|bait|bait|prey fbxa-196 skr-2 MI:0398(two hybrid pooling approach)|MI:0398(two hybrid pooling approach) 19123269 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_18988|UniProt_20898 bait|bait prey|prey fbxa-196 Q93647 MI:0018(two hybrid) 18692475 taxid:6239(Caenorhabditis elegans) taxid:0() MI:0915(physical association) MI:0471(mint) MINT_4913 prey bait

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID O16525 H2L0F6 FBXA-196 GEI-4 0.332 19123269,14704431 Q93647 O16525 Q93647 FBXA-196 0.183 18692475 O16525 G5EDD8 FBXA-196 SKR-2 0.236 19123269 Q9XV35 O16525 MADF-2 FBXA-196 0.236 19123269 O16525 G5ECU1 FBXA-196 SKR-1 0.376 19123269,unassigned701 Q9TZ39 O16525 Q9TZ39 FBXA-196 0.033 14704431