PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus F57F5.1 Y44E3A.4 23549480 intact exp G Y44E3A.4 sop-2 23549480 intact exp G Y44E3A.4 Y116A8C.36a 23549480 intact exp G Uncharacterized protein F10E9.3 Y44E3A.4 23549480 intact exp T27E9.1a Y44E3A.4 23549480 intact exp G Y44E3A.4 F29G6.3b 23549480 intact exp G C01H6.7a Y44E3A.4 23549480 intact exp G LIM and SH3 domain protein F42H10.3 Y44E3A.4 23549480 intact exp G vav-1 Y44E3A.4 23549480 intact exp G Y44E3A.4 Y105E8A.21a 23549480 intact exp G cpr-6 Y44E3A.4 23549480 intact exp G eft-3, eft-4 Y44E3A.4 23549480 intact exp Y44E3A.4 C31C9.6 23549480 intact exp ZK1248.10 Y44E3A.4 23549480 intact exp G F29D10.4 Y44E3A.4 23549480 intact exp G T08G5.5b Y44E3A.4 23549480 intact exp G fln-1 Y44E3A.4 23549480 intact exp G C18F3.2c, SAX-7 LONGFORM Y44E3A.4 23549480 intact exp G Ack related non-receptor tyrosine kinase, C01C7.1a Y44E3A.4 23549480 intact exp F52G2.3 Y44E3A.4 23549480 intact exp Y44E3A.4 Y44E3A.6b 23549480 intact exp G R02F2.5 Y44E3A.4 23549480 intact exp F09F7.5a Y44E3A.4 23549480 intact exp Y44E3A.4 ZK858.2 23549480 intact exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants D0IMZ5 Q6A573 two hybrid 23549480 physical association X 2 Q6A573 Q8I4M6 two hybrid 23549480 physical association X 2 Q6A573 G3MU69 two hybrid 23549480 physical association X 2 Q45FX5 Q6A573 two hybrid 23549480 physical association X 2 Q20950 Q6A573 two hybrid 23549480 physical association X 2 Q8ITV6 Q6A573 two hybrid 23549480 physical association X 2 Q21648 Q6A573 two hybrid 23549480 physical association X 2 P43510 Q6A573 two hybrid 23549480 physical association X 2 Q965H3 Q6A573 two hybrid 23549480 physical association X 2 Q18100 Q6A573 two hybrid 23549480 physical association X 2 Q23419 Q6A573 two hybrid 23549480 physical association X 2 C6KRP0 Q6A573 two hybrid 23549480 physical association X 2 A5JYT2 Q6A573 two hybrid 23549480 physical association X 2 A5JYT2 Q6A573 two hybrid 23549480 physical association X 2 O62256 Q6A573 two hybrid 23549480 physical association X 2 A8JJR1 Q6A573 two hybrid 23549480 physical association X 2 Q6A573 Q19275 two hybrid 23549480 physical association X 2 Q6A573 P34397 two hybrid 23549480 physical association X 2 Q6A573 E3W743 two hybrid 23549480 physical association X 2 Q6A573 P53013 two hybrid 23549480 physical association X 2 Q6A573 Q9U2T9 two hybrid 23549480 physical association X 2 Q19901 Q6A573 two hybrid 23549480 physical association X 2 E8MDW3 Q6A573 two hybrid 23549480 physical association X 2 Q94418 Q6A573 two hybrid 23549480 physical association X 2 P34416 Q6A573 two hybrid 23549480 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B F57F5.1 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24043 prey bait CELE_Y44E3A.4 Y44E3A.6 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24036 bait prey CELE_Y44E3A.4 sop-2 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24040 bait prey CELE_Y44E3A.4 ZK858.2 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24486 bait prey sax-7 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24038 prey bait CELE_Y44E3A.4 swsn-9 MI:0018(two hybrid)|MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_24031|UniProt_24483 bait|bait prey|prey CELE_Y44E3A.4 ark-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24030 bait prey F10E9.3 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24034 prey bait CELE_Y44E3A.4 C31C9.6 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24032 bait prey vav-1 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23555 bait prey tbc-2 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24037 prey bait CELE_Y44E3A.4 ant-1.1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24045 bait prey R02F2.5 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24484 prey bait CELE_Y44E3A.4 itsn-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23469 prey bait F42H10.3 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23619 bait prey hum-1 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_23591 bait prey F09F7.5 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24033 prey bait eft-3 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24042 prey bait cpr-6 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24039 prey bait CELE_Y44E3A.4 hpo-34 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24041 bait prey CELE_F52G2.3 CELE_Y44E3A.4 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24035 prey bait CELE_Y44E3A.4 fln-1 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24046 bait prey CELE_Y44E3A.4 CELE_Y105E8A.21 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24485 bait prey CELE_Y44E3A.4 vps-39 MI:0018(two hybrid) 23549480 taxid:6239(Caenorhabditis elegans) taxid:6239(Caenorhabditis elegans) MI:0915(physical association) (intact) UniProt_24044 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q6A573 Q18100 Q6A573 SAX-7 0.183 23549480 Q6A573 Q21648 Q6A573 Q21648 0.183 23549480 Q6A573 Q19275 Q6A573 Q19275 0.183 23549480 Q6A573 Q19901 Q6A573 HUM-1 0.183 23549480 Q6A573 O62256 Q6A573 O62256 0.183 23549480 Q94418 Q6A573 Q94418 Q6A573 0.183 23549480 Q6A573 P53013 Q6A573 EFT-4 0.183 23549480 Q6A573 E3W743 Q6A573 HPO-34 0.183 23549480 Q6A573 P34397 Q6A573 P34397 0.183 23549480 Q8ITV6 Q6A573 Q8ITV6 Q6A573 0.183 23549480 Q6A573 Q45FX5 Q6A573 VAV-1 0.183 23549480 Q8I4M6 Q6A573 Q8I4M6 Q6A573 0.183 23549480 Q965H3 Q6A573 SOP-2 Q6A573 0.183 23549480 Q9U2T9 Q6A573 ITSN-1 Q6A573 0.183 23549480 Q6A573 P34416 Q6A573 P34416 0.183 23549480 Q6A573 D0IMZ5 Q6A573 FLN-1 0.183 23549480 Q6A573 E8MDW3 Q6A573 E8MDW3 0.183 23549480 Q6A573 P43510 Q6A573 CPR-6 0.183 23549480 Q6A573 G3MU69 Q6A573 ANT-1.1 0.183 23549480 Q6A573 G5EBZ8 Q6A573 ARK-1 {ECO:0000312|WORMBASE:C01C7.1A} 0.183 23549480 Q6A573 A5JYT2 Q6A573 SWSN-9 0.332 23549480 Q6A573 A8JJR1 Q6A573 VPS-39 0.183 23549480 Q6A573 Q20950 Q6A573 Q20950 0.183 23549480 Q6A573 Q23419 Q6A573 TBC-2 0.183 23549480