PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ATG8 ATG32 22308029,19619494,23559066,21757540 biogrid,intact exp ATG8 SVP26 23904270 biogrid exp ATG8 PEP8 23904270 biogrid exp ATG8 FTH1 23904270 biogrid exp SSA3 ATG8 19536198 intact exp DNF1 ATG8 23904270 biogrid exp SEC63 ATG8 22240591 biogrid exp VPH1 ATG8 22240591 biogrid exp ATG8 MPS1 21460040 biogrid exp ATG8 DNF2 23904270 biogrid exp ATG8 YIP3 23904270 biogrid exp ATG8 KSP1 16319894 biogrid,i2d exp ATG8 ERV46 23904270 biogrid exp APM3 ATG8 23904270 biogrid exp ATG8 ERP1 23904270 biogrid exp ATG8 YPT31 23904270 biogrid exp ATG8 DID2 23904270 biogrid exp SSB1 ATG8 19536198 intact exp ATG8 PIL1 23904270 biogrid exp ATG8 VTH1 23904270 biogrid exp PMR1 ATG8 23904270 biogrid exp ATG8 FKS1 23904270 biogrid exp ATG8 SSP120 23904270 biogrid exp ATG8 CUE5 25042851 biogrid,intact exp COY1 ATG8 23904270 biogrid exp SSO1 ATG8 23904270 biogrid exp SAC6 ATG8 23904270 biogrid exp HMG2 ATG8 21228276 biogrid exp PHO85 ATG8 16319894 biogrid,i2d exp ATG8 SEC26 23904270 biogrid exp STV1 ATG8 23904270 biogrid exp VPS1 ATG8 23904270 biogrid exp ATG8 ATG10 23142976 dip exp EMP24 ATG8 23904270 biogrid exp ATG8 VPS13 23904270 biogrid exp SWE1 ATG8 i2d exp ATG8 ATG34 20639194,11283351,24705553,18719252 biogrid,i2d,mint,intact,dip exp ATG8 YCK3 23904270 biogrid exp ATG8 ATG36 23559066,22643220 biogrid,intact exp ATG8 YOP1 23904270 biogrid exp ATG8 AKR2 23904270 biogrid exp TVP38 ATG8 23904270 biogrid exp ATG8 DRS2 23904270 biogrid exp ATG8 SED5 23904270 biogrid exp ATG8 SEC16 23904270 biogrid exp ATG8 AKR1 23904270 biogrid exp ELO2 ATG8 23904270 biogrid exp ATG8 EMP47 23904270 biogrid exp SFT2 ATG8 23904270 biogrid exp VPS17 ATG8 23904270 biogrid exp ATG8 SUR7 23904270 biogrid exp ATG8 ATG9 22826123 biogrid exp CMK1 ATG8 16319894 biogrid,i2d exp ATG8 NEO1 23904270 biogrid exp ATG8 SFT1 23904270 biogrid exp NAB2 ATG8 19840948 biogrid exp SEC22 ATG8 23904270 biogrid exp ATG8 GVP36 23904270 biogrid exp SEC21 ATG8 23904270 biogrid exp SEC23 ATG8 23904270 biogrid exp, ortho ATG8 ERV25 23904270 biogrid exp, ortho YPT1 ATG8 23904270, 23023127 biogrid exp, ortho, pred ATG8 ATG7 22325599,11139573,22056771,22055191,12965207,19398890,18719252,10688190,11100732,25042851, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred ATG8 ATG4 18971623,9649430,25483965,11038174,18719252, 23023127 biogrid,i2d,intact,dip exp, ortho, pred YPT7 ATG8 23904270, 23023127 biogrid exp, ortho, pred SHP1 ATG8 20855502, 23023127 biogrid exp, pred ATG8 RSP5 25042851, 23023127 biogrid exp, pred VPS21 ATG8 23904270, 23023127 biogrid exp, pred ATG8 TLG2 23904270, 23023127 biogrid exp, pred CDC48 ATG8 20855502,23904270, 23023127 biogrid exp, pred ATG8 GOS1 23904270, 23023127 biogrid exp, pred BET1 ATG8 23904270,10837468, 23023127 biogrid,intact,dip exp, pred SSA2 ATG8 19536198, 23023127 intact exp, pred ATG8 ATG1 16319894,23043107,22885598,22778255, 23023127 biogrid,i2d,intact exp, pred ATG8 VAM3 10837468, 23023127 biogrid,dip exp, pred ATG8 ATG12 17986448, 23023127 biogrid exp, pred ATG8 SNF7 23904270,22240591, 23023127 biogrid exp, pred SEC4 ATG8 23904270, 23023127 biogrid exp, pred SEC17 ATG8 23904270,10837468, 23023127 biogrid exp, pred APE1 ATG8 22123825,24705553,19398890, 23023127 biogrid,dip exp, pred ATG8 CRC1 16093310, 23023127 biogrid,mint,intact,dip exp, pred YCK1 ATG8 16319894,23904270, 23023127 biogrid exp, pred ATG8 VTI1 23904270, 23023127 biogrid exp, pred ATG8 NYV1 10837468, 23023127 biogrid,intact,dip exp, pred PEP12 ATG8 23904270, 23023127 biogrid exp, pred ATG8 ATP14 16554755, 23023127 biogrid,i2d,mint,intact exp, pred SAR1 ATG8 23904270, 23023127 biogrid exp, pred RHO1 ATG8 23904270, 23023127 biogrid exp, pred ATG8 ATG3 22539722,22325599,17986448,22056771,11283351,19285500,15277523,23503366,25461810,18719252,11100732,25042851,20615880,17227760, 23023127 biogrid,i2d,mint,intact,dip exp, pred ATG19 ATG8 19021777,19619494,20615880,24705553,19398890,11675395, 23023127 biogrid,dip exp, pred ATG8 ATG5 17986448, 23023127 biogrid exp, pred ATG8 GDB1 ortho RPL30 ATG8 ortho MDH1 ATG8 ortho BRR2 ATG8 ortho SSC1 ATG8 ortho PSE1 ATG8 ortho KAR2 ATG8 ortho ATP5 ATG8 ortho URA2 ATG8 ortho TRX3 ATG8 ortho RPS3 ATG8 ortho RPS13 ATG8 ortho HSP60 ATG8 ortho ADE3 ATG8 ortho NAP1 ATG8 ortho RPB3 ATG8 ortho SDH2 ATG8 ortho PRX1 ATG8 ortho SNU114 ATG8 ortho ATG8 MEX67 ortho TOP1 ATG8 ortho ATG8 SAH1 ortho KRS1 ATG8 ortho EFB1 ATG8 ortho TPI1 ATG8 ortho PRC1 ATG8 ortho GPM1 ATG8 ortho ATG8 RPS20 ortho PRE7 ATG8 ortho HMT1 ATG8 ortho ATG8 SMD2 ortho ATG8 RPS7B ortho PGK1 ATG8 ortho CRM1 ATG8 ortho TCP1 ATG8 ortho TSA1 ATG8 ortho RPL22A ATG8 ortho DBP2 ATG8 ortho ATG8 NIF3 ortho ATG8 BNA3 ortho CDC19 ATG8 ortho ATG8 PHB1 ortho SCL1 ATG8 ortho CHC1 ATG8 ortho ATG8 CCT3 ortho ATG8 ALD5 ortho ATG8 TSA2 ortho ATP2 ATG8 ortho TUB2 ATG8 ortho ATG8 CCT8 ortho ATG8 FOX2 ortho ATG8 RAT1 ortho ATG8 SEC24 ortho RPS5 ATG8 ortho RPS31 ATG8 ortho LPD1 ATG8 ortho ATG8 RRP45 ortho RPL5 ATG8 ortho RPT5 ATG8 ortho SSE2 ATG8 ortho SIS1 ATG8 ortho ATG8 ATG8 ortho RPP0 ATG8 ortho ATG8 PRP43 ortho RPS2 ATG8 ortho ATP1 ATG8 ortho ATG8 CCT2 ortho MCM5 ATG8 ortho POR1 ATG8 ortho ATG8 HSP10 ortho ATG8 SDH1 ortho CPR3 ATG8 ortho ATG8 URA8 ortho PWP1 ATG8 ortho SPT16 ATG8 ortho TPD3 ATG8 ortho ATG8 CKB2 ortho ATG8 BRX1 ortho ATG8 Protein-glutamate O-methyltransferase ortho SSE1 ATG8 ortho RPO21 ATG8 ortho LAT1 ATG8 ortho ATG8 RVB2 ortho RPL3 ATG8 ortho YKU70 ATG8 ortho PRE1 ATG8 ortho ATG8 CCT4 ortho CTA1 ATG8 ortho ADE5,7 ATG8 ortho MCM3 ATG8 ortho PUB1 ATG8 ortho ATG8 LSM2 ortho CAP2 ATG8 ortho ATG8 RIM20 ortho ATG8 SFB3 ortho ATP3 ATG8 ortho ATG8 RRB1 ortho TUB1 ATG8 ortho PEP4 ATG8 23023127 ortho, pred ATG8 MYO5 23023127 pred YPT52 ATG8 23023127 pred ATG8 LSB3 23023127 pred ATG8 UBI4 23023127 pred ARF2 ATG8 23023127 pred MYO3 ATG8 23023127 pred ATG8 VPS9 23023127 pred ARF1 ATG8 23023127 pred ATG8 UBX6 23023127 pred ATG8 MVP1 23023127 pred GSP2 ATG8 23023127 pred ATG8 UBC12 23023127 pred ATG8 UBP3 23023127 pred ATG8 ATG20 23023127 pred ATG8 VPS27 23023127 pred ATG8 RVS167 23023127 pred MSP1 ATG8 23023127 pred ATG8 UBC11 23023127 pred ATG8 SGT1 23023127 pred ATG8 VPS36 23023127 pred CDC34 ATG8 23023127 pred ATG8 SKP1 23023127 pred ATG8 VPS30 23023127 pred ATG8 APS2 23023127 pred ATG8 VAM10 23023127 pred ATG8 ATG13 23023127 pred DOA4 ATG8 23023127 pred SEC18 ATG8 23023127 pred RAD6 ATG8 23023127 pred ATG8 HSE1 23023127 pred ATG8 GGA1 23023127 pred RVS161 ATG8 23023127 pred SLA1 ATG8 23023127 pred ARL1 ATG8 23023127 pred YPT53 ATG8 23023127 pred UBC1 ATG8 23023127 pred ERD2 ATG8 23023127 pred ATG8 UBC13 23023127 pred UBC6 ATG8 23023127 pred ATG8 ARL3 23023127 pred UBC4 ATG8 23023127 pred UBA1 ATG8 23023127 pred ATG8 APL4 23023127 pred ATG8 UBX3 23023127 pred ATG8 UBP6 23023127 pred ATG8 VPS4 23023127 pred PAN1 ATG8 23023127 pred ATG8 ULP1 23023127 pred ATG8 VID24 23023127 pred ATG8 UBX5 23023127 pred UBC8 ATG8 23023127 pred ATG8 UBP14 23023127 pred ATG8 HUB1 23023127 pred ATG8 LIN1 23023127 pred ATG8 SMT3 23023127 pred VPS15 ATG8 23023127 pred GSP1 ATG8 23023127 pred ATG8 GGA2 23023127 pred APS1 ATG8 23023127 pred ATG8 NBP2 23023127 pred YUH1 ATG8 23023127 pred PRB1 ATG8 23023127 pred PEP5 ATG8 23023127 pred ATG8 UBA2 23023127 pred ATG8 UBX7 23023127 pred PBI2 ATG8 23023127 pred UBC5 ATG8 23023127 pred SLA2 ATG8 23023127 pred EDE1 ATG8 23023127 pred ATG8 UBC9 23023127 pred VPS24 ATG8 23023127 pred RAS2 ATG8 23023127 pred ATG8 ARF3 23023127 pred YSC84 ATG8 23023127 pred ATG8 UBC7 23023127 pred ATG8 UBP15 23023127 pred SNC2 ATG8 23023127 pred GLK1 ATG8 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P38182 P38862 - 10688190 - X 2 P38182 P53867 - 9649430 - X 2 Q12292 P38182 - 11283351 - X 2 P40344 P38182 - 10655498 - X 2 P40344 P38182 - 11283351 - X 2 Q66K14 P38182 two hybrid 22354992 direct interaction X 2 Q12289 P38182 protein complementation assay 16093310 direct interaction X 2 Q12241 P38182 affinity chromatography technology 10837468 physical association X 2 P39929 P38182 imaging technique 22240591 colocalization X 2 P38182 Q9UPU7-3 two hybrid 22354992 direct interaction X 2 P38182 Q12255 affinity chromatography technology 10837468 physical association X 2 P38182 Q12255 affinity chromatography technology 10837468 physical association X 2 P38182 P38862 two hybrid 12965207 direct interaction X 2 P38182 P38862 affinity chromatography technology 11100732 physical association X 2 P38182 P53867 pull down 11038174 direct interaction X 2 P38182 P53867 two hybrid 9649430 direct interaction X 2 P38182 P53867 affinity chromatography technology 9649430 physical association X 2 P38182 P38862 two hybrid 11139573 direct interaction X 2 P38182 P38862 affinity chromatography technology 11139573 physical association X 2 P38182 P46983 two hybrid 23559066 direct interaction X 2 P38182 P38862 pull down 22325599 direct interaction X 2 P38182 Q08412 affinity chromatography technology 25042851 physical association X 2 P38182 Q08412 affinity chromatography technology 25042851 physical association X 2 P38182 P38862 affinity chromatography technology 25042851 physical association X 2 P38182 Q08412 affinity chromatography technology 25042851 physical association X 2 P38182 P53867 enzymatic study 25180519 direct interaction X 2 P38182 P23291 enzymatic study 16319894 direct interaction X 2 P38182 P38862 two hybrid 18719252 direct interaction X 2 P38182 P53867 two hybrid 18719252 direct interaction X 2 P38182 P38862 affinity chromatography technology 19398890 physical association X 2 P38182 P53867 enzymatic study 18971623 direct interaction X 2 P38182 P38862 two hybrid 19398890 direct interaction X 2 P38182 P38862 pull down 22055191 direct interaction X 2 P38182 P38862 x-ray crystallography 22055191 association X 2 P38182 P38862 pull down 22056771 direct interaction X 2 P38182 P38862 x-ray crystallography 22056771 association X 2 P38182 P38862 two hybrid 10688190 direct interaction X 2 P38182 P46983 affinity chromatography technology 22643220 physical association X 2 O60238 P38182 two hybrid 20010802 direct interaction X 2 P34223 P38182 affinity chromatography technology 20855502 physical association X 2 P34223 P38182 pull down 20855502 direct interaction X 2 P34223 P38182 protein complementation assay 20855502 direct interaction X 2 P54199 P38182 pull down 21460040 direct interaction X 2 Q12142 P38182 biochemical 22826123 colocalization X 2 P38316 P38182 enzymatic study 17986448 direct interaction X 2 P14904 P38182 affinity chromatography technology 19398890 physical association X 2 P14904 P38182 imaging technique 22123825 colocalization X 2 P35193 P38182 x-ray crystallography 19021777 association X 2 P35193 P38182 affinity chromatography technology 11675395 physical association X 2 P35193 P38182 unspecified method 19021777 direct interaction X 2 P35193 P38182 two hybrid 19021777 direct interaction X 2 P35193 P38182 pull down 19021777 direct interaction X 2 P35193 P38182 two hybrid 19619494 direct interaction X 2 P35193 P38182 affinity chromatography technology 19398890 physical association X 2 P35193 P38182 pull down 20615880 direct interaction X 2 P35193 P38182 two hybrid 19398890 direct interaction X 2 P40458 P38182 two hybrid 19619494 direct interaction X 2 P40458 P38182 affinity chromatography technology 19619494 physical association X 2 P40458 P38182 two hybrid 21757540 direct interaction X 2 P40458 P38182 x-ray crystallography 22308029 association X 2 P40458 P38182 affinity chromatography technology 22308029 physical association X 2 P40458 P38182 two hybrid 22308029 direct interaction X 2 P27466 P38182 enzymatic study 16319894 direct interaction X 2 Q12292 P38182 two hybrid 18719252 direct interaction X 2 Q12292 P38182 two hybrid 20639194 direct interaction X 2 P12684 P38182 affinity chromatography technology 21228276 physical association X 2 P38691 P38182 enzymatic study 16319894 direct interaction X 2 P14906 P38182 imaging technique 22240591 colocalization X 2 P38182 P53104 two hybrid 22778255 direct interaction X 2 P38182 P53104 affinity chromatography technology 22778255 physical association X 2 P38182 two hybrid 21617041 direct interaction X 2 P38182 Q13501 two hybrid 21617041 direct interaction X 2 P38182 affinity chromatography technology 21617041 physical association X 2 P38182 P22804 affinity chromatography technology 10837468 physical association X 2 P38182 P22804 affinity chromatography technology 10837468 physical association X 2 P38182 P32602 affinity chromatography technology 10837468 physical association X 2 P38182 P53104 biochemical 22885598 association X 2 P38182 P53104 affinity chromatography technology 23043107 physical association X 2 P38182 Q9Y4P1 two hybrid 20010802 direct interaction X 2 P38182 A0A024R1V3 two hybrid 20010802 direct interaction X 2 P38182 Q13501 two hybrid 20010802 direct interaction X 2 P38182 P25694 pull down 20855502 direct interaction X 2 P38182 Q12349 affinity chromatography technology 16554755 physical association X 2 P38182 P53104 enzymatic study 16319894 direct interaction X 2 P38182 P17157 enzymatic study 16319894 direct interaction X 2 P38182 P32563 imaging technique 22240591 colocalization X 2 Q6FIE9 P38182 affinity chromatography technology 25042851 physical association X 2 P40344 P38182 affinity chromatography technology 11100732 physical association X 2 P40344 P38182 enzymatic study 23503366 direct interaction X 2 P40344 P38182 enzymatic study 17986448 direct interaction X 2 P40344 P38182 enzymatic study 22325599 direct interaction X 2 P40344 P38182 enzymatic study 15277523 direct interaction X 2 P40344 P38182 pull down 22325599 direct interaction X 2 P40344 P38182 affinity chromatography technology 25042851 physical association X 2 P40344 P38182 pull down 25461810 direct interaction X 2 P40344 P38182 two hybrid 11283351 direct interaction X 2 P40344 P38182 pull down 17227760 direct interaction X 2 P40344 P38182 two hybrid 18719252 direct interaction X 2 P40344 P38182 pull down 19285500 direct interaction X 2 P40344 P38182 pull down 20615880 direct interaction X 2 P40344 P38182 two hybrid 11283351 direct interaction X 2 P40344 P38182 pull down 22056771 direct interaction X 2 P40344 P38182 affinity chromatography technology 22539722 physical association X 2 Q12380 P38182 enzymatic study 17986448 direct interaction X 2 P39940 P38182 affinity chromatography technology 25042851 physical association X 2 P38182 molecular sieving 22056771 physical association C 3 P38182 molecular sieving 22056771 physical association C 3 Q12289 P38182 ubiquitin reconstruction 16093310 physical association X 2 Q12241 P38182 coimmunoprecipitation 10837468 physical association X 2 P38182 P53867 affinity chromatography technology 9649430 physical association X 2 P38182 P53867 two hybrid 9649430 physical association X 2 P38182 Q12255 coimmunoprecipitation 10837468 physical association X 2 P38182 P38862 comigration in sds page 22056771 covalent binding X 2 P38182 P38862 x-ray crystallography 22056771 covalent binding X 2 P38182 P38862 comigration in sds page 22056771 covalent binding X 2 P38182 P38862 coimmunoprecipitation 11100732 covalent binding X 2 P38182 P38862 two hybrid 11139573 covalent binding X 2 P38182 P38862 molecular sieving 22056771 covalent binding X 2 P38182 P38862 molecular sieving 22056771 covalent binding X 2 P38182 P38862 comigration in sds page 23142976 covalent binding X 2 P38182 P38862 two hybrid 10688190 covalent binding X 2 P38182 P38862 coimmunoprecipitation 11139573 covalent binding X 2 P14904 P38182 pull down 24705553 physical association X 2 P35193 P38182 anti tag coimmunoprecipitation 24705553 direct interaction X 2 P35193 P38182 pull down 24705553 direct interaction X 2 P35193 P38182 isothermal titration calorimetry 24705553 direct interaction X 2 P35193 P38182 molecular sieving 24705553 direct interaction X 2 P35193 P38182 pull down 24705553 direct interaction X 2 Q07879 P38182 comigration in sds page 23142976 covalent binding X 2 Q12292 P38182 pull down 24705553 direct interaction X 2 Q12292 P38182 molecular sieving 24705553 direct interaction X 2 Q12292 P38182 two hybrid pooling approach 11283351 direct interaction X 2 P38182 P22804 coimmunoprecipitation 10837468 physical association X 2 P40344 P38182 two hybrid 10655498 covalent binding X 2 P40344 P38182 two hybrid pooling approach 11283351 covalent binding X 2 P40344 P38182 molecular sieving 22056771 covalent binding X 2 P40344 P38182 coimmunoprecipitation 11100732 covalent binding X 2 P40344 P38182 comigration in sds page 23142976 covalent binding X 2 P38182 anti tag coimmunoprecipitation 25042851 association C 4 P38182 anti bait coimmunoprecipitation 10837468 association C 3 P10592 P38182 tandem affinity purification 19536198 association X 2 Q12289 P38182 ubiquitin reconstruction 16093310 physical association X 2 P42858 P38182 anti tag coimmunoprecipitation 25042851 physical association X 2 P38182 P38862 two hybrid 10688190 physical association X 2 P38182 P38862 two hybrid 12965207 physical association X 2 P38182 P53867 two hybrid 18719252 physical association X 2 P38182 P38862 two hybrid 18719252 physical association X 2 P38182 P46983 two hybrid 23559066 physical association X 2 P38182 P46983 two hybrid 23559066 physical association X 2 P38182 Q08412 anti tag coimmunoprecipitation 25042851 physical association X 2 P38182 Q08412 pull down 25042851 direct interaction X 2 P38182 Q08412 anti tag coimmunoprecipitation 25042851 physical association X 2 P38182 P53867 two hybrid 9649430 physical association X 2 P38182 P53867 pull down 9649430 physical association X 2 O60238 P38182 two hybrid 20010802 physical association X 2 P40458 P38182 two hybrid 23559066 physical association X 2 P38182 anti bait coimmunoprecipitation 10837468 association C 3 Q12292 P38182 two hybrid fragment pooling approach 11283351 physical association X 2 Q12292 P38182 two hybrid 18719252 physical association X 2 P11484 P38182 tandem affinity purification 19536198 association X 2 P38182 P22804 anti bait coimmunoprecipitation 10837468 physical association X 2 P38182 Q12349 inferred by author 16554755 association X 2 P38182 Q12349 tandem affinity purification 16554755 physical association X 2 P38182 A0A024R1V3 pull down 19250911 physical association X 2 P38182 Q13501 pull down 19250911 physical association X 2 P38182 A0A024R1V3 pull down 19250911 physical association X 2 P38182 A0A024R1V3 pull down 19250911 physical association X 2 P38182 A0A024R1V3 pull down 19250911 physical association X 2 P38182 A0A024R1V3 two hybrid 19250911 physical association X 2 P38182 Q13501 two hybrid 19250911 physical association X 2 P38182 A0A024R1V3 two hybrid 19250911 physical association X 2 P38182 Q13501 two hybrid 19250911 physical association X 2 P38182 P09435 tandem affinity purification 19536198 association X 2 P38182 Q9Z2F7 pull down 20010802 direct interaction X 2 P38182 Q9Y4P1 two hybrid 20010802 physical association X 2 P38182 A0A024R1V3 two hybrid 20010802 physical association X 2 P38182 P53104 pull down 22885598 direct interaction X 2 P38182 P53104 pull down 22885598 direct interaction X 2 P38182 P53104 pull down 22885598 physical association X 2 Q6FIE9 P38182 anti tag coimmunoprecipitation 25042851 physical association X 2 P40344 P38182 two hybrid fragment pooling approach 11283351 physical association X 2 P40344 P38182 two hybrid 18719252 physical association X 2 P40344 P38182 biochemical 19285500 direct interaction X 2 P38182 confirmational text mining - - C 14 P38182 P53867 confirmational text mining - - X 2 P38182 P38862 two hybrid 10688190 - X 2 P38182 P53867 interaction detection method 9649430 - X 2 P38182 P53867 cosedimentation through density gradient 9649430 - X 2 Q12292 P38182 two hybrid 11283351 - X 2 P40344 P38182 two hybrid 11283351 - X 2 P40344 P38182 two hybrid 10655498 - X 2

PPI - HINT Gene A Gene B PMID Method Quality PHO85 ATG8 16319894 0415 LC BET1 ATG8 10837468,10837468,10837468 0004,0019,0006 LC YCK1 ATG8 16319894 0415 LC CMK1 ATG8 16319894 0415 LC SAS3 ATG8 20855502,20855502,20855502 0096,0090,0004 LC ATG19 ATG8 19619494,19398890,24705553,24705553,19021777,24705553,24705553,19021777,19021777,19398890 0018,0018,0071,0096,0018,0065,0007,0114,0096,0004 LC ATG8 ATG12 17986448 0415 LC ATG8 KSP1 16319894 0415 LC ATG8 ATG7 19398890,18719252,11139573,12965207,22055191,11100732,11100732,11139573,22055191,11139573,23142976,22056771,10688190,22056771,22056771,10688190,22056771,19398890 0018,0018,0004,0018,0114,0004,0019,0019,0096,0018,0808,0071,0018,0808,0114,0397,0096,0004 LC,HT ATG8 ATG3 15277523,17986448,23503366,19285500,19285500,11100732,11283351,11283351,23142976,10655498,22325599,18719252,11283351,22056771,22056771,11100732,22325599 0415,0415,0415,0096,0401,0004,0398,0399,0808,0018,0096,0018,0018,0096,0071,0019,0415 LC,HT ATG8 ATG32 19619494,22308029,22308029,22308029,21757540,23559066,19619494 0018,0114,0004,0018,0018,0018,0004 LC ATG8 ATG36 23559066 0018 LC ATG8 ATG1 22885598,16319894,22778255,22778255,22885598 0401,0415,0004,0018,0096 LC ATG8 ATG4 18719252,9649430,9649430,25483965,9649430,9649430,18971623 0018,0004,0018,0415,0096,0029,0415 HT,LC ATG8 ATG39 26040717,26040717 0004,0018 LC ATG8 ATG10 23142976 0808 LC ATG8 ATG9 22826123 0401 LC ATG8 VAM3 10837468,10837468 0004,0019 LC ATG8 NYV1 10837468,10837468,10837468 0004,0019,0006 LC ATG8 CRC1 16093310,16093310 0090,0112 HT ATG8 ATG34 18719252,11283351,11283351,11283351,24705553,24705553,20639194 0018,0018,0399,0398,0071,0096,0018 HT,LC ATG8 ATG5 17986448 0415 LC ATG8 ATG40 26040717,26040717 0004,0018 LC YPT1 ATG8 23904270 0004 LC RHO1 ATG8 23904270 0004 LC SEC4 ATG8 23904270 0004 LC SSA3 ATG8 19536198 0676 HT SSA2 ATG8 19536198 0676 HT SSB1 ATG8 19536198 0676 HT HMG2 ATG8 21228276 0004 LC PMR1 ATG8 23904270 0004 LC APE1 ATG8 22123825,24705553,19398890 0428,0096,0004 LC SEC63 ATG8 22240591 0428 LC SEC23 ATG8 23904270 0004 LC SAR1 ATG8 23904270 0004 LC VPS1 ATG8 23904270 0004 LC SEC22 ATG8 23904270 0004 LC BET1 ATG8 10837468,10837468,10837468,23904270 0004,0019,0006,0004 LC YCK1 ATG8 23904270 0004 LC ELO2 ATG8 23904270 0004 LC CDC48 ATG8 20855502,20855502,23904270 0096,0004,0004 LC SEC21 ATG8 23904270 0004 LC NAB2 ATG8 19840948 0004 LC VPH1 ATG8 22240591 0428 LC SAC6 ATG8 23904270 0004 LC DNF1 ATG8 23904270 0004 LC EMP24 ATG8 23904270 0004 LC PEP12 ATG8 23904270 0004 LC SSO1 ATG8 23904270 0004 LC VPS17 ATG8 23904270 0004 LC YPT7 ATG8 23904270 0004 LC SAS3 ATG8 20855502,10837468,20855502,20855502,23904270 0096,0004,0090,0004,0004 LC COY1 ATG8 23904270 0004 LC ATG19 ATG8 19398890,20615880,24705553,24705553,19021777,24705553,11675395,24705553,19021777,19021777,19398890 0018,0096,0071,0096,0018,0065,0004,0007,0114,0096,0004 LC VPS21 ATG8 23904270 0004 LC TVP38 ATG8 23904270 0004 LC STV1 ATG8 23904270 0004 LC APM3 ATG8 23904270 0004 LC SFT2 ATG8 23904270 0004 LC ATG8 FTH1 23904270 0004 LC ATG8 YPT31 23904270 0004 LC ATG8 FKS1 23904270 0004 LC ATG8 GOS1 23904270 0004 LC ATG8 ATG7 22325599,19398890,11139573,22055191,11100732,11100732,11139573,22055191,11139573,25042851,22056771,25042851,22056771,22056771,22056771,19398890 0096,0018,0004,0114,0004,0019,0019,0096,0018,0004,0071,0007,0808,0114,0096,0004 LC ATG8 SVP26 23904270 0004 LC ATG8 AKR1 23904270 0004 LC ATG8 DRS2 23904270 0004 LC ATG8 ERV46 23904270 0004 LC ATG8 SNF7 22240591,23904270 0428,0004 LC ATG8 SSP120 23904270 0004 LC ATG8 RSP5 25042851 0004 LC ATG8 YCK3 23904270 0004 LC ATG8 PEP8 23904270 0004 LC ATG8 ATG3 19285500,19285500,20615880,11100732,22539722,25461810,25042851,22325599,25042851,22056771,22056771,17227760,11100732,22325599 0096,0401,0096,0004,0004,0096,0004,0096,0007,0096,0071,0096,0019,0415 LC ATG8 VTH1 23904270 0004 LC ATG8 ATG32 19619494,26296886,22308029,22308029,22308029,19619494 0018,0004,0114,0004,0018,0004 LC ATG8 NEO1 23904270 0004 LC ATG8 GVP36 23904270 0004 LC ATG8 SEC26 23904270 0004 LC ATG8 EMP47 23904270 0004 LC ATG8 SFT1 23904270 0004 LC ATG8 ATG36 22643220 0004 LC ATG8 SEC16 23904270 0004 LC ATG8 ATG1 22885598,22778255,22778255,22885598,23043107 0401,0004,0018,0096,0004 LC ATG8 PIL1 23904270 0004 LC ATG8 YIP3 23904270 0004 LC ATG8 ATG4 9649430,11038174,9649430,9649430,9649430 0004,0096,0018,0096,0029 LC ATG8 SUR7 23904270 0004 LC ATG8 MPS1 21460040 0096 LC ATG8 ERV25 23904270 0004 LC ATG8 DID2 23904270 0004 LC ATG8 SED5 23904270 0004 LC ATG8 VTI1 23904270 0004 LC ATG8 ERP1 23904270 0004 LC ATG8 ATG39 26040717,26040717 0004,0018 LC ATG8 VPS13 23904270 0004 LC ATG8 TLG2 23904270 0004 LC ATG8 CUE5 25042851,25042851,25042851 0004,0096,0007 LC ATG8 AKR2 23904270 0004 LC ATG8 ATG9 22826123 0401 LC ATG8 VAM3 10837468,10837468 0004,0019 LC ATG8 NYV1 10837468,10837468,10837468 0004,0019,0006 LC ATG8 ATG34 24705553,24705553 0071,0096 LC ATG8 ATP14 16554755,16554755,16554755 0363,0676,0004 HT ATG8 YOP1 23904270 0004 LC ATG8 DNF2 23904270 0004 LC ATG8 ATG40 26040717,26040717 0004,0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53104 P38182 ATG1 ATG8 0.848 22885598,16319894,22778255,23043107 P38182 P22804 ATG8 BET1 0.472 10837468,23904270 P38182 P17157 ATG8 PHO85 0.183 16319894 P38182 O43379 ATG8 WDR62 0.332 27107014 Q12142 P38182 ATG9 ATG8 0.126 22826123 Q12380 P38182 ATG5 ATG8 0.309 17986448 P38182 O60238 ATG8 BNIP3L 0.681 27107014,20010802 Q9H0E2 P38182 TOLLIP ATG8 0.21 25042851 Q9Z2F7 P38182 BNIP3L ATG8 0.309 20010802 P38182 P10592 ATG8 SSA2 0.126 19536198 P38182 P09435 ATG8 SSA3 0.126 19536198 Q14596 P38182 NBR1 ATG8 0.702 20010802,19250911 Q08412 P38182 CUE5 ATG8 0.659 25042851 P46983 P38182 ATG36 ATG8 0.74 23559066,22643220 P53867 P38182 ATG4 ATG8 0.681 18971623,9649430,25483965,18719252 Q99325 P38182 Q99325 ATG8 0.454 26040717 P38182 P25694 ATG8 CDC48 0.396 23904270,20855502 P39929 P38182 SNF7 ATG8 0.236 23904270,22240591 Q06159 P38182 Q06159 ATG8 0.454 26040717 Q92609 P38182 TBC1D5 ATG8 0.332 27107014 P40458 P38182 ATG32 ATG8 0.922 22308029,23559066,19619494,26296886,21757540 P40344 P38182 ATG3 ATG8 0.99 25461810,20615880,22056771,23503366,11100732,10655498,22325599,15277523,18719252,22539722,19285500,25042851,17986448,11283351 P38182 P35193 ATG8 ATG19 0.959 19398890,19021777,19619494,20615880,24705553 P38862 P38182 ATG7 ATG8 0.977 10688190,25042851,22056771,12965207,11100732,11139573,22325599,18719252,22055191,19398890 P38182 P01123 ATG8 YPT1 0.126 23904270 P38182 P06780 ATG8 RHO1 0.126 23904270 P38182 P07149 ATG8 FAS1 0.376 25605918 P38182 P07560 ATG8 SEC4 0.126 23904270 P38182 P11484 ATG8 SSB1 0.126 19536198 P38182 P12684 ATG8 HMG2 0.21 21228276 P38182 P13586 ATG8 PMR1 0.126 23904270 P38182 P14904 ATG8 LAP4 0.309 22123825,19398890 P38182 P14906 ATG8 SEC63 0.126 22240591 P38182 P15303 ATG8 SEC23 0.126 23904270 P38182 P19097 ATG8 FAS2 0.376 25605918 P38182 P20606 ATG8 SAR1 0.126 23904270 P38182 P21576 ATG8 VPS1 0.126 23904270 P38182 P22214 ATG8 SEC22 0.126 23904270 P38182 P23291 ATG8 YCK1 0.286 23904270,16319894 P38182 P25358 ATG8 FEN1 0.126 23904270 P38182 P32074 ATG8 SEC21 0.126 23904270 P38182 P32563 ATG8 VPH1 0.126 22240591 P38182 P32599 ATG8 SAC6 0.126 23904270 P38182 P32602 ATG8 SEC17 0.126 23904270 P38182 P32660 ATG8 DNF1 0.126 23904270 P38182 P32803 ATG8 EMP24 0.126 23904270 P38182 P32854 ATG8 PEP12 0.126 23904270 P38182 P32867 ATG8 SSO1 0.126 23904270 P38182 P32913 ATG8 VPS17 0.126 23904270 P38182 P32939 ATG8 YPT7 0.126 23904270 P38182 P34237 ATG8 COY1 0.126 23904270 P38182 P36017 ATG8 VPS21 0.126 23904270 P38182 P36164 ATG8 TVP38 0.126 23904270 P38182 P37296 ATG8 STV1 0.126 23904270 P38182 P38153 ATG8 APM3 0.126 23904270 P38182 P38166 ATG8 SFT2 0.126 23904270 P38310 P38182 FTH1 ATG8 0.126 23904270 P38555 P38182 YPT31 ATG8 0.126 23904270 P38631 P38182 FKS1 ATG8 0.126 23904270 P38736 P38182 GOS1 ATG8 0.126 23904270 P38869 P38182 SVP26 ATG8 0.126 23904270 P39010 P38182 AKR1 ATG8 0.126 23904270 P39524 P38182 DRS2 ATG8 0.126 23904270 P39727 P38182 ERV46 ATG8 0.126 23904270 P39931 P38182 SSP120 ATG8 0.126 23904270 P39962 P38182 YCK3 ATG8 0.126 23904270 P40335 P38182 PEP8 ATG8 0.126 23904270 P40438 P38182 VTH1 ATG8 0.126 23904270 P40527 P38182 NEO1 ATG8 0.126 23904270 P40531 P38182 GVP36 ATG8 0.126 23904270 P41810 P38182 SEC26 ATG8 0.126 23904270 P41834 P38182 UFE1 ATG8 0.21 26876173 P43555 P38182 EMP47 ATG8 0.126 23904270 P43682 P38182 SFT1 ATG8 0.126 23904270 P48415 P38182 SEC16 ATG8 0.126 23904270 P53252 P38182 PIL1 ATG8 0.126 23904270 P53633 P38182 YIP3 ATG8 0.126 23904270 P54003 P38182 SUR7 ATG8 0.126 23904270 P54837 P38182 ERV25 ATG8 0.126 23904270 P69771 P38182 DID2 ATG8 0.126 23904270 Q01590 P38182 SED5 ATG8 0.126 23904270 Q04338 P38182 VTI1 ATG8 0.126 23904270 Q05359 P38182 ERP1 ATG8 0.126 23904270 Q07878 P38182 VPS13 ATG8 0.126 23904270 Q08144 P38182 TLG2 ATG8 0.126 23904270 Q12013 P38182 AKR2 ATG8 0.126 23904270 Q12241 P38182 VAM3 ATG8 0.033 10837468 Q12255 P38182 NYV1 ATG8 0.376 10837468 Q12289 P38182 CRC1 ATG8 0.286 16093310 Q12292 P38182 ATG34 ATG8 0.74 11283351,20639194,24705553,18719252 Q12349 P38182 ATP14 ATG8 0.332 16554755 Q12402 P38182 YOP1 ATG8 0.126 23904270 Q12675 P38182 DNF2 ATG8 0.126 23904270 Q66K14 P38182 TBC1D9B ATG8 0.183 22354992 Q96CV9 P38182 OPTN ATG8 0.523 21617041 Q96GX9 P38182 APIP ATG8 0.332 27107014 Q9UPU7 P38182 TBC1D2B ATG8 0.183 22354992 Q9Y4P1 P38182 ATG4B ATG8 0.523 20010802 P38316 P38182 ATG12 ATG8 0.309 17986448 P38691 P38182 KSP1 ATG8 0.183 16319894 P38182 P32505 ATG8 NAB2 0.126 19840948 P38182 P27466 ATG8 CMK1 0.183 16319894 Q9UH92 P38182 MLX ATG8 0.332 27107014 P38182 P34223 ATG8 SHP1 0.623 20855502 Q13501 P38182 SQSTM1 ATG8 0.722 21617041,19250911,20010802 P42858 P38182 HTT ATG8 0.21 25042851 Q12983 P38182 BNIP3 ATG8 0.332 27107014 P54199 P38182 MPS1 ATG8 0.183 21460040