PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SRO77 IES1 16554755 biogrid,i2d,mint,intact exp KIN3 SRO77 10688190,11489916 biogrid,i2d,mint,intact,dip exp NAB2 SRO77 19840948 biogrid exp SRO77 NIP7 i2d exp SRO77 TAF1 i2d exp SRO77 MCA1 11489916,10688190 biogrid,i2d,mint,intact,dip exp SHE2 SRO77 17339339 biogrid exp SRO77 APP1 10688190,11489916 biogrid,i2d,mint,intact,dip exp DTR1 SRO77 16554755 intact exp SRO77 ATG17 11489916 biogrid,i2d,dip exp NFS1 SRO77 10688190 mint,intact,dip exp SBA1 SRO77 16554755 biogrid,i2d,mint,intact exp BCY1 SRO77 11489916,10688190 biogrid,i2d,mint,intact,dip exp DBF2 SRO77 16319894 biogrid,i2d exp SRO77 SSB2 23332755 biogrid exp SRO77 YAP1801 11489916, 23023127 biogrid,i2d,dip exp, pred NIP100 SRO77 10688190,11489916, 23023127 biogrid,i2d,mint,intact,dip exp, pred SRO77 SEC9 10402465, 23023127 biogrid,i2d,intact,dip exp, pred SRO77 ENT2 10688190,11489916, 23023127 biogrid,i2d,mint,intact,dip exp, pred SRO77 YIP1 11489916,10688190, 23023127 biogrid,i2d,mint,intact,dip exp, pred SRO77 EXO84 16027223, 23023127 biogrid exp, pred SRO77 SFB3 10688190, 23023127 mint,intact,dip exp, pred GMH1 SRO77 10688190, 23023127 mint,intact,dip exp, pred SRO77 SRO7 23023127 pred GCS1 SRO77 23023127 pred MYO3 SRO77 23023127 pred SRO77 YPT32 23023127 pred SEC4 SRO77 23023127 pred SEC3 SRO77 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P0CG63 P38163 biochemical 23583075 association X 2 P38163 P07278 two hybrid 11489916 direct interaction X 2 P38163 P22209 two hybrid 11489916 direct interaction X 2 P53039 P38163 two hybrid 11489916 direct interaction X 2 P38856 P38163 two hybrid 11489916 direct interaction X 2 P53933 P38163 two hybrid 11489916 direct interaction X 2 Q06410 P38163 two hybrid 11489916 direct interaction X 2 P43579 P38163 affinity chromatography technology 16554755 physical association X 2 Q08601 P38163 two hybrid 11489916 direct interaction X 2 P33420 P38163 two hybrid 11489916 direct interaction X 2 P38163 P40357 pull down 10402465 direct interaction X 2 P38163 Q05785 two hybrid 11489916 direct interaction X 2 P38163 P38261 two hybrid 16027223 direct interaction X 2 P38163 P28707 affinity chromatography technology 16554755 physical association X 2 P40150 P38163 biochemical 23332755 association X 2 P22204 P38163 enzymatic study 16319894 direct interaction X 2 P38163 inferred by author 16554755 association C 8 P38163 P22209 two hybrid 10688190 physical association X 2 P38163 P07278 two hybrid 10688190 physical association X 2 P53039 P38163 two hybrid 10688190 physical association X 2 P53933 P38163 two hybrid 10688190 physical association X 2 P43579 P38163 tandem affinity purification 16554755 physical association X 2 Q08601 P38163 two hybrid 10688190 physical association X 2 P38810 P38163 two hybrid 10688190 physical association X 2 P25374 P38163 two hybrid 10688190 physical association X 2 P33420 P38163 two hybrid 10688190 physical association X 2 P38163 P40357 pull down 10402465 direct interaction X 2 P38163 Q05785 two hybrid 10688190 physical association X 2 P38163 P36125 two hybrid 10688190 physical association X 2 P38163 P28707 tandem affinity purification 16554755 physical association X 2 P38163 P19524 interaction detection method 9691031 - X 2 P38163 P19524 interaction detection method 9691031 - X 2 P38163 P07278 two hybrid 11489916 - X 2 P38163 P22209 two hybrid 11489916 - X 2 P38163 P07278 two hybrid 11489916 - X 2 P38163 P22209 two hybrid 11489916 - X 2 P53039 P38163 two hybrid 11489916 - X 2 P53039 P38163 two hybrid 11489916 - X 2 P38856 P38163 two hybrid 11489916 - X 2 P38856 P38163 two hybrid 11489916 - X 2 P53933 P38163 two hybrid 11489916 - X 2 P53933 P38163 two hybrid 11489916 - X 2 Q06410 P38163 two hybrid 11489916 - X 2 Q06410 P38163 two hybrid 11489916 - X 2 Q08601 P38163 two hybrid 11489916 - X 2 Q08601 P38163 two hybrid 11489916 - X 2 P33420 P38163 two hybrid 11489916 - X 2 P33420 P38163 two hybrid 11489916 - X 2 P38163 Q00245 interaction detection method 9691031 - X 2 P38163 P40357 interaction detection method 10402465 - X 2 P38163 P40357 protein cross-linking with a bifunctional reagent 10402465 - X 2 P38163 Q00245 interaction detection method 9691031 - X 2 P38163 Q00245 interaction detection method 9691031 - X 2 P38163 Q05785 two hybrid 11489916 - X 2 P38163 Q05785 two hybrid 11489916 - X 2 P08964 P38163 interaction detection method 9691031 - X 2 P08964 P38163 interaction detection method 9691031 - X 2

PPI - HINT Gene A Gene B PMID Method Quality BCY1 SRO77 11489916,10688190 0018,0018 HT DBF2 SRO77 16319894 0415 LC KIN3 SRO77 11489916,10688190 0018,0018 HT NFS1 SRO77 10688190 0018 HT NIP100 SRO77 11489916,10688190 0018,0018 HT GMH1 SRO77 10688190 0018 HT SRO77 EXO84 16027223 0018 LC SRO77 SFB3 10688190 0018 HT SRO77 YAP1801 11489916 0018 HT SRO77 SSB2 23332755 0401 LC SRO77 SEC9 10402465,10402465,10402465 0031,0096,0004 LC SRO77 YIP1 11489916,10688190 0018,0018 HT SRO77 APP1 11489916,10688190 0018,0018 HT SRO77 ENT2 11489916,10688190 0018,0018 HT SRO77 ATG17 11489916 0018 HT SRO77 MCA1 11489916,10688190 0018,0018 HT SBA1 SRO77 16554755,16554755 0676,0004 HT NAB2 SRO77 19840948 0004 LC SHE2 SRO77 17339339 0004 LC DTR1 SRO77 16554755 0363 HT SRO77 SSB2 23332755 0401 LC SRO77 SEC9 10402465,10402465,10402465 0031,0096,0004 LC SRO77 IES1 16554755,16554755 0676,0004 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P38163 P25374 SRO77 NFS1 0.183 10688190 P43579 P38163 IES1 SRO77 0.236 16554755 P38163 P38125 SRO77 DTR1 0.126 16554755 P38163 P07278 SRO77 BCY1 0.332 10688190,11489916 P38163 P22209 SRO77 KIN3 0.332 10688190,11489916 P38163 P28707 SRO77 SBA1 0.236 16554755 P38163 P33420 SRO77 NIP100 0.332 10688190,11489916 P38810 P38163 SFB3 SRO77 0.21 10688190 P38856 P38163 YAP1801 SRO77 0.21 11489916 P40357 P38163 SEC9 SRO77 0.033 10402465 P53039 P38163 YIP1 SRO77 0.332 10688190,11489916 P53933 P38163 APP1 SRO77 0.332 10688190,11489916 Q05785 P38163 ENT2 SRO77 0.332 10688190,11489916 Q06410 P38163 ATG17 SRO77 0.183 11489916 Q08601 P38163 MCA1 SRO77 0.332 10688190,11489916 P38261 P38163 EXO84 SRO77 0.309 16027223 P38163 P32505 SRO77 NAB2 0.126 19840948 P38163 P36125 SRO77 GMH1 0.183 10688190 P38163 P22204 SRO77 DBF2 0.183 16319894