PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RPL40B UBP14 16554755 biogrid,i2d exp UBP14 GPD2 11283351 i2d,mint,intact,dip exp UBP14 MMS22 i2d exp SSA1 UBP14 16429126,19536198 intact exp STH1 UBP14 i2d exp GDH2 UBP14 i2d exp UBP14 UBA4 9305625 biogrid exp FBP1 UBP14 20457600 biogrid exp SAC6 UBP14 i2d exp UBP14 FRA1 i2d exp RPS31 UBP14 i2d exp HSP26 UBP14 i2d exp UBC1 UBP14 i2d exp SPT6 UBP14 i2d exp UBP14 ECM10 16554755 biogrid,mint,intact exp UBP14 MYO5 11743162 mint exp SSB1 UBP14 16429126,19536198 intact exp VMA2 UBP14 16429126 intact exp HIS5 UBP14 i2d exp STU1 UBP14 i2d exp PHO4 UBP14 i2d exp UBP14 Putative pyridoxal reductase, PL reductase, PL-red i2d exp CMD1 UBP14 i2d exp HSP78 UBP14 19536198 intact exp UBP14 RTT10 i2d exp UBP14 NCB2 i2d exp UBP14 LYS12 i2d exp UBP14 HXT11 11283351 i2d,mint,intact,dip exp ILS1 UBP14 11805826,16429126 biogrid,mint,intact,dip exp DBP5 UBP14 i2d exp UBI4 UBP14 15096053,16007098,16554755 biogrid,i2d,mint,intact exp UBP14 PDS1 22072716 biogrid exp UBP14 PSP2 i2d exp SSC1 UBP14 i2d exp NIP1 UBP14 11805826,16429126 biogrid,mint,intact,dip exp DED1 UBP14 16429126 intact exp UBP14 IKI3 i2d exp RPL4A UBP14 16429126 intact exp UBP14 TAP42 i2d exp RPB9 UBP14 i2d exp RPP0 UBP14 16429126 intact exp RPL40A UBP14 16007098 i2d,dip exp UBP14 SEC16 16554755 biogrid,i2d,mint,intact exp ILV2 UBP14 i2d exp SCD5 UBP14 i2d exp SEM1 UBP14 i2d exp UBP14 SSB2 23332755 biogrid exp UBP14 Uncharacterized protein YLR177W i2d exp UBP14 TCB3 i2d exp MYO3 UBP14 11743162 mint exp UBP14 PFS2 i2d exp UBP14 PUF2 i2d exp PRE1 UBP14 i2d exp RPL5 UBP14 16429126 intact exp UBP14 BFR1 i2d exp UBP14 BUR2 i2d exp UBP14 TOF1 i2d exp UBP14 RPN8 i2d exp UBP14 DIG2 i2d exp UBP14 ARC40 i2d exp UBP14 ARC1 i2d exp UBP14 BRO1 i2d exp UBP14 RVS167 16554755, 23023127 biogrid,i2d,mint,intact exp, pred UBP14 GAS4 11283351, 23023127 i2d,mint,intact,dip exp, pred UBP14 SKM1 11283351, 23023127 i2d,mint,intact,dip exp, pred UBP14 LYS20 16554755, 23023127 biogrid,mint,intact exp, pred MET22 UBP14 11283351, 23023127 i2d,mint,intact,dip exp, pred UBP14 UBP9 23023127 i2d exp, pred UBP14 MLC1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred UBP14 HUA1 11283351, 23023127 i2d,mint,intact,dip exp, pred UBP14 UBP15 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CYC8 UBP14 16554755, 23023127 biogrid,i2d,mint,intact exp, pred TOP1 UBP14 16554755, 23023127 biogrid,i2d,mint,intact exp, pred SOL2 UBP14 16554755, 23023127 biogrid,mint,intact exp, pred UBP14 UBP14 11805826, 23023127 mint,intact exp, pred PAB1 UBP14 16429126, 23023127 intact exp, pred ADH1 UBP14 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred UBP14 LEO1 11283351, 23023127 i2d,mint,intact,dip exp, pred FMP46 UBP14 16554755, 23023127 biogrid,i2d,mint,intact exp, pred UBP14 RPN11 20170199, 23023127 biogrid exp, pred RAD23 UBP14 23023127 pred UBP14 RUP1 23023127 pred SHP1 UBP14 23023127 pred UBP14 CUE5 23023127 pred EDE1 UBP14 23023127 pred UBP14 VID30 23023127 pred UBP14 RSP5 23023127 pred UBP14 URM1 23023127 pred MPE1 UBP14 23023127 pred UBP14 UBX4 23023127 pred UBP14 ATG12 23023127 pred UBP14 CUE1 23023127 pred UBP14 HUB1 23023127 pred UBP14 DDI1 23023127 pred UBP14 UBP6 23023127 pred UBP14 DSK2 23023127 pred UBP14 RUB1 23023127 pred ATG8 UBP14 23023127 pred UBP14 UBI4 23023127 pred UBP14 SMT3 23023127 pred UBP14 PCL10 23023127 pred UBP14 UBP5 23023127 pred UBP14 VID24 23023127 pred UBC8 UBP14 23023127 pred CUE2 UBP14 23023127 pred UBP14 UBX3 23023127 pred UBP14 UBX7 23023127 pred UBP14 UBX6 23023127 pred UBP14 UBX5 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P38237 P40325 - 11283351 - X 2 P38237 Q12469 - 11283351 - X 2 P38237 P41911 - 11283351 - X 2 P38237 P32179 - 11283351 - X 2 P38237 Q08271 - 11283351 - X 2 P38237 P54862 - 11283351 - X 2 P38237 P38439 - 11283351 - X 2 P38237 P48570 affinity chromatography technology 16554755 physical association X 2 P38237 P39743 affinity chromatography technology 16554755 physical association X 2 P38237 P39987 affinity chromatography technology 16554755 physical association X 2 P38237 P50101 affinity chromatography technology 16554755 physical association X 2 P38237 P04786 affinity chromatography technology 16554755 physical association X 2 P38237 P09201 affinity chromatography technology 20457600 physical association X 2 P38237 P32497 affinity chromatography technology 11805826 physical association X 2 P48415 P38237 affinity chromatography technology 16554755 physical association X 2 P0CG63 P38237 affinity chromatography technology 23749301 physical association X 2 P0CG63 P38237 biochemical 23583075 association X 2 P0CG63 P38237 affinity chromatography technology 17644757 physical association X 2 P0CG63 P38237 pull down 16007098 direct interaction X 2 P0CG63 P38237 affinity chromatography technology 15096053 physical association X 2 P0CG63 P38237 affinity chromatography technology 21427232 physical association X 2 P0CG63 P38237 affinity chromatography technology 22106047 physical association X 2 P09436 P38237 affinity chromatography technology 11805826 physical association X 2 P38237 P40316 enzymatic study 22072716 direct interaction X 2 P38237 P38820 enzymatic study 9305625 direct interaction X 2 P38237 P40150 biochemical 23332755 association X 2 P38237 P14922 affinity chromatography technology 16554755 physical association X 2 P38237 P53141 affinity chromatography technology 16554755 physical association X 2 P38237 P0CH08 affinity chromatography technology 16554755 physical association X 2 P38237 P37262 affinity chromatography technology 16554755 physical association X 2 P38237 P36141 affinity chromatography technology 16554755 physical association X 2 P38237 P43588 affinity chromatography technology 20170199 physical association X 2 P38237 P00330 affinity chromatography technology 11805826 physical association X 2 P38237 tandem affinity purification 11805826 association C 5 P38237 tandem affinity purification 11805826 association C 5 P38237 Q12469 two hybrid fragment pooling approach 11283351 physical association X 2 P38237 P40325 two hybrid fragment pooling approach 11283351 physical association X 2 P38237 P50101 tandem affinity purification 16554755 physical association X 2 P38237 P04786 tandem affinity purification 16554755 physical association X 2 P38237 P50101 tandem affinity purification 16554755 physical association X 2 P38237 P50101 tandem affinity purification 16554755 physical association X 2 P38237 P50101 tandem affinity purification 16554755 physical association X 2 P38237 P50101 tandem affinity purification 16554755 physical association X 2 P38237 P50101 tandem affinity purification 16554755 physical association X 2 P38237 P50101 tandem affinity purification 16554755 physical association X 2 P38237 P04786 tandem affinity purification 16554755 physical association X 2 P38237 P48570 tandem affinity purification 16554755 physical association X 2 P38237 P39987 tandem affinity purification 16554755 physical association X 2 P38237 P39987 tandem affinity purification 16554755 physical association X 2 P38237 P39743 tandem affinity purification 16554755 physical association X 2 P38237 P39743 tandem affinity purification 16554755 physical association X 2 P38237 P50101 tandem affinity purification 16554755 physical association X 2 P38237 P48570 tandem affinity purification 16554755 physical association X 2 P48415 P38237 tandem affinity purification 16554755 physical association X 2 P0CG63 P38237 tandem affinity purification 16554755 physical association X 2 P0CG63 P38237 tandem affinity purification 16554755 physical association X 2 P0CG63 P38237 tandem affinity purification 16554755 physical association X 2 P38237 inferred by author 16554755 association C 3 P38237 tandem affinity purification 16429126 association C 12 P38237 P41911 two hybrid fragment pooling approach 11283351 physical association X 2 P38237 P32179 two hybrid fragment pooling approach 11283351 physical association X 2 P38237 Q08271 two hybrid fragment pooling approach 11283351 physical association X 2 P38237 P54862 two hybrid fragment pooling approach 11283351 physical association X 2 P38237 P38439 two hybrid fragment pooling approach 11283351 physical association X 2 P38237 P37262 tandem affinity purification 16554755 physical association X 2 P38237 P53141 tandem affinity purification 16554755 physical association X 2 P38237 P53141 tandem affinity purification 16554755 physical association X 2 P38237 P14922 tandem affinity purification 16554755 physical association X 2 P38237 P14922 tandem affinity purification 16554755 physical association X 2 P38237 P36141 tandem affinity purification 16554755 physical association X 2 P38237 P11484 tandem affinity purification 19536198 association X 2 P38237 P33416 tandem affinity purification 19536198 association X 2 P10591 P38237 tandem affinity purification 19536198 association X 2 P38237 mass spectrometry studies of complexes 11805826 - C 5 P38237 mass spectrometry studies of complexes 11805826 - C 5 P38237 Q12469 two hybrid 11283351 - X 2 P38237 P40325 two hybrid 11283351 - X 2 P38237 P41911 two hybrid 11283351 - X 2 P38237 P32179 two hybrid 11283351 - X 2 P38237 Q08271 two hybrid 11283351 - X 2 P38237 P54862 two hybrid 11283351 - X 2 P38237 P38439 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality MET22 UBP14 11283351,11283351,11283351 0018,0399,0398 HT UBP14 LEO1 11283351,11283351,11283351 0018,0399,0398 HT UBP14 UBA4 9305625 0415 LC UBP14 SSB2 23332755 0401 LC UBP14 PDS1 22072716 0415 LC UBP14 HUA1 11283351,11283351,11283351 0018,0399,0398 HT UBP14 GPD2 11283351,11283351,11283351 0018,0399,0398 HT UBP14 HXT11 11283351,11283351,11283351 0018,0399,0398 HT UBP14 GAS4 11283351,11283351,11283351 0018,0399,0398 HT UBP14 SKM1 11283351,11283351,11283351 0018,0399,0398 HT ADH1 UBP14 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT PAB1 UBP14 16429126 0676 HT TOP1 UBP14 16554755,16554755 0676,0004 HT RPP0 UBP14 16429126 0676 HT DED1 UBP14 16429126 0676 HT FBP1 UBP14 20457600 0004 LC ILS1 UBP14 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT UBI4 UBP14 16007098,15096053,16554755,15096053,22106047 0096,0096,0676,0004,0004 LC,HT RPL40A UBP14 16554755 0004 HT RPL40B UBP14 16554755 0004 HT SSA1 UBP14 19536198,16429126 0676,0676 HT RPL4A UBP14 16429126 0676 HT SSB1 UBP14 19536198,16429126 0676,0676 HT CYC8 UBP14 16554755,16554755,16554755 0363,0676,0004 HT VMA2 UBP14 16429126 0676 HT RPL5 UBP14 16429126 0676 HT NIP1 UBP14 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT HSP78 UBP14 19536198 0676 HT FMP46 UBP14 16554755,16554755 0676,0004 HT SOL2 UBP14 16554755,16554755 0676,0004 HT UBP14 UBP14 11805826,11805826 0676,0007 HT UBP14 RVS167 16554755,16554755 0676,0004 HT UBP14 ECM10 16554755,16554755 0676,0004 HT UBP14 SSB2 23332755 0401 LC UBP14 RPN11 20170199 0004 LC UBP14 SEC16 16554755,16554755 0676,0004 HT UBP14 LYS20 16554755,16554755 0676,0004 HT UBP14 UBP15 16554755,16554755 0676,0004 HT UBP14 MLC1 16554755,16554755 0676,0004 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53141 P38237 MLC1 UBP14 0.332 16554755 P38237 P09201 UBP14 FBP1 0.21 20457600 P38237 P00330 UBP14 ADH1 0.416 11805826,16429126 P38237 P09436 UBP14 ILS1 0.416 11805826,16429126 P38237 P11484 UBP14 SSB1 0.236 16429126,19536198 P38237 P36141 UBP14 FMP46 0.236 16554755 P38237 P04147 UBP14 PAB1 0.126 16429126 P38237 P04786 UBP14 TOP1 0.332 16554755 P38237 P05317 UBP14 RPP0 0.126 16429126 P38237 P06634 UBP14 DED1 0.126 16429126 P38237 P0CG63 UBP14 UBI4 0.583 16554755,16007098,15096053 P38237 P0CH08 UBP14 RPL40A 0.126 16554755 P38237 P0CH09 UBP14 RPL40B 0.126 16554755 P38237 P10591 UBP14 SSA1 0.236 16429126,19536198 P38237 P10664 UBP14 RPL4A 0.126 16429126 P38237 P14922 UBP14 CYC8 0.332 16554755 P38237 P16140 UBP14 VMA2 0.126 16429126 P38237 P26321 UBP14 RPL5 0.126 16429126 P38237 P32179 UBP14 MET22 0.236 11283351 P38237 P37262 UBP14 SOL2 0.126 16554755 P38237 P38237 UBP14 UBP14 0.155 11805826 P38439 P38237 LEO1 UBP14 0.236 11283351 P38820 P38237 UBA4 UBP14 0.309 9305625 P40316 P38237 PDS1 UBP14 0.309 22072716 P40325 P38237 HUA1 UBP14 0.236 11283351 P48415 P38237 SEC16 UBP14 0.236 16554755 P50101 P38237 UBP15 UBP14 0.332 16554755 Q08271 P38237 GAS4 UBP14 0.236 11283351 Q12469 P38237 SKM1 UBP14 0.236 11283351 P38237 P32497 UBP14 NIP1 0.416 11805826,16429126 P39743 P38237 RVS167 UBP14 0.332 16554755 P38237 P33416 UBP14 HSP78 0.126 19536198 P39987 P38237 ECM10 UBP14 0.332 16554755 P43588 P38237 RPN11 UBP14 0.126 20170199 P48570 P38237 LYS20 UBP14 0.332 16554755 P41911 P38237 GPD2 UBP14 0.21 11283351 P54862 P38237 HXT11 UBP14 0.21 11283351