PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HSP60 GID7 11805837 dip exp GID7 CCT3 19536198 intact exp GID7 HSP78 19536198 intact exp GDH1 GID7 11805837 dip exp ACO1 GID7 i2d exp GID7 NAB2 19840948 biogrid exp MET6 GID7 11805837 dip exp PGI1 GID7 11805837 dip exp LEU2 GID7 11805837 dip exp PAB1 GID7 11805837 dip exp GID7 SSE1 19536198 intact exp GID7 HXT7 11805837 biogrid,intact,dip exp GID7 NAM7 18087042 biogrid exp PDC1 GID7 11805837 dip exp GID7 MOH1 11805837 biogrid,mint,intact,dip exp ENO1 GID7 11805837 dip exp GID7 SHS1 11805837 biogrid,intact,dip exp GID7 CCT8 11805837 dip exp ATP2 GID7 11805837 dip exp VMA1 GID7 11805837, 23023127 biogrid,intact,dip exp, pred GID7 VID28 11805837, 23023127 biogrid,intact,dip exp, pred GID7 JEM1 19536198, 23023127 intact exp, pred GID7 GID7 18467557, 23023127 biogrid,i2d,mint,intact exp, pred GID7 UME1 11805837, 23023127 biogrid,mint,intact,dip exp, pred GID7 GID8 18719252,11805837, 23023127 biogrid,mint,intact,dip exp, pred GID7 NUP116 11283351, 23023127 i2d,mint,intact,dip exp, pred GID7 FYV10 16554755,11805837, 23023127 biogrid,mint,intact,dip exp, pred GID7 CTF19 11805837, 23023127 biogrid,mint,intact,dip exp, pred GID7 VID24 11805837, 23023127 biogrid,intact,dip exp, pred GID7 RMD5 11805837, 23023127 biogrid,intact,dip exp, pred GID7 VID30 18508925,16429126,22645139,16554755,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred FUS1 GID7 19841731, 23023127 mint,intact exp, pred GID7 UBC8 23023127 pred GID7 RPN14 23023127 pred TUP1 GID7 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P25569 - 11805837 - C 9 P25569 - 11805837 - C 8 P25569 - 11805837 - C 7 P25569 - 11805837 - C 6 P25569 - 11805837 - C 6 Q02630 P25569 - 11283351 - X 2 P25569 P40208 - 11805837 - X 2 P40492 P25569 affinity chromatography technology 11805837 physical association X 2 P0CG63 P25569 affinity chromatography technology 23749301 physical association X 2 P0CG63 P25569 affinity chromatography technology 23793018 physical association X 2 Q07657 P25569 affinity chromatography technology 11805837 physical association X 2 Q12508 P25569 affinity chromatography technology 11805837 physical association X 2 P25569 P53076 affinity chromatography technology 16554755 physical association X 2 P25569 P53076 biochemical 18508925 colocalization X 2 P25569 P53076 affinity chromatography technology 11805837 physical association X 2 P25569 P53076 affinity chromatography technology 22645139 physical association X 2 Q02732 P25569 affinity chromatography technology 11805837 physical association X 2 P40547 P25569 affinity chromatography technology 11805837 physical association X 2 P39004 P25569 affinity chromatography technology 11805837 physical association X 2 P38191 P25569 affinity chromatography technology 11805837 physical association X 2 P38191 P25569 affinity chromatography technology 11805837 physical association X 2 P38263 P25569 affinity chromatography technology 11805837 physical association X 2 P25569 P25569 protein complementation assay 18467557 direct interaction X 2 P25569 P40208 two hybrid 18719252 direct interaction X 2 P25569 P40208 affinity chromatography technology 11805837 physical association X 2 P25569 Q03010 affinity chromatography technology 11805837 physical association X 2 P17255 P25569 affinity chromatography technology 11805837 physical association X 2 P25569 anti tag coimmunoprecipitation 11805837 - C 23 P25569 anti tag coimmunoprecipitation 11805837 - C 9 P25569 anti tag coimmunoprecipitation 11805837 - C 13 P40492 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P04147 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P06169 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 Q07657 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P00924 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P07262 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12508 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P25569 P53076 anti tag coimmunoprecipitation 11805837 physical association X 2 P00830 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 Q02732 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P40547 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P25569 anti tag coimmunoprecipitation 11805837 - C 18 P19882 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P39004 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P38191 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P38191 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 Q02630 P25569 two hybrid pooling approach 11283351 physical association X 2 P38263 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P04173 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P25569 P47079 anti tag coimmunoprecipitation 11805837 physical association X 2 P25569 P40208 anti tag coimmunoprecipitation 11805837 physical association X 2 P25569 Q03010 anti tag coimmunoprecipitation 11805837 physical association X 2 P17255 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P05694 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P12709 P25569 anti tag coimmunoprecipitation 11805837 physical association X 2 P25569 anti tag coimmunoprecipitation 11805837 association C 9 P25569 inferred by author 16554755 association C 8 P32589 P25569 tandem affinity purification 19536198 association X 2 P40358 P25569 tandem affinity purification 19536198 association X 2 P25569 P53076 tandem affinity purification 16554755 physical association X 2 P25569 P53076 tandem affinity purification 16554755 physical association X 2 P25569 P33416 tandem affinity purification 19536198 association X 2 P25569 anti tag coimmunoprecipitation 11805837 association C 8 P25569 anti tag coimmunoprecipitation 11805837 association C 7 P25569 tandem affinity purification 16429126 association C 8 P25569 anti tag coimmunoprecipitation 11805837 association C 6 P25569 anti tag coimmunoprecipitation 11805837 association C 6 P39077 P25569 tandem affinity purification 19536198 association X 2 P11710 P25569 inferred by author 19841731 direct interaction X 2 Q02630 P25569 two hybrid fragment pooling approach 11283351 physical association X 2 P25569 P40208 anti tag coimmunoprecipitation 11805837 physical association X 2 P25569 P25569 dihydrofolate reductase reconstruction 18467557 physical association X 2 P25569 P40208 two hybrid 18719252 physical association X 2 P25569 mass spectrometry studies of complexes 11805837 - C 10 Q02630 P25569 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality GID7 GID7 18467557,18467557 0111,0090 HT GID7 GID8 18719252 0018 HT GID7 VID30 18508925 0401 LC GID7 NUP116 11283351,11283351,11283351 0018,0399,0398 HT ATP2 GID7 11805837 0007 HT ENO1 GID7 11805837 0007 HT PAB1 GID7 11805837 0007 HT LEU2 GID7 11805837 0007 HT MET6 GID7 11805837 0007 HT PDC1 GID7 11805837 0007 HT GDH1 GID7 11805837 0007 HT FUS1 GID7 19841731 0363 LC PGI1 GID7 11805837 0007 HT VMA1 GID7 11805837,11805837 0004,0007 HT HSP60 GID7 11805837 0007 HT GID7 NAB2 19840948 0004 LC GID7 SSE1 19536198 0676 HT GID7 HSP78 19536198 0676 HT GID7 MOH1 11805837,11805837 0004,0007 HT GID7 VID24 11805837,11805837 0004,0007 HT GID7 HXT7 11805837,11805837 0004,0007 HT GID7 CCT3 19536198 0676 HT GID7 GID8 11805837,11805837 0004,0007 HT GID7 JEM1 19536198 0676 HT GID7 FYV10 11805837,16554755,11805837 0004,0363,0007 HT GID7 VID28 11805837,11805837 0004,0007 HT GID7 CCT8 11805837 0007 HT GID7 VID30 11805837,16554755,16429126,16554755,22645139,11805837,18508925,22645139 0004,0004,0676,0676,0007,0007,0401,0004 HT,LC GID7 CTF19 11805837,11805837 0004,0007 HT GID7 UME1 11805837,11805837 0004,0007 HT GID7 SHS1 11805837,11805837 0004,0007 HT GID7 RMD5 11805837,11805837 0004,0007 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53076 P25569 VID30 GID7 0.765 22645139,16429126,18508925,16554755,11805837 Q12221 P25569 PUF2 GID7 0.126 26668354 P25569 P00830 GID7 ATP2 0.126 11805837 P25569 P00924 GID7 ENO1 0.126 11805837 P25569 P05694 GID7 MET6 0.126 11805837 P25569 P07262 GID7 GDH1 0.126 11805837 P25569 P11710 GID7 FUS1 0.332 19841731 P33416 P25569 HSP78 GID7 0.126 19536198 P38191 P25569 MOH1 GID7 0.454 11805837 P39004 P25569 HXT7 GID7 0.21 11805837 P40208 P25569 GID8 GID7 0.539 11805837,18719252 P40358 P25569 JEM1 GID7 0.126 19536198 P25569 P12709 GID7 PGI1 0.126 11805837 P25569 P04147 GID7 PAB1 0.126 11805837 P25569 P04173 GID7 LEU2 0.126 11805837 P25569 P06169 GID7 PDC1 0.126 11805837 P25569 P25569 GID7 GID7 0.332 18467557 P30771 P25569 NAM7 GID7 0.126 18087042 P38263 P25569 VID24 GID7 0.332 11805837 P32505 P25569 NAB2 GID7 0.126 19840948 P32589 P25569 SSE1 GID7 0.126 19536198 P39077 P25569 CCT3 GID7 0.126 19536198 P40492 P25569 FYV10 GID7 0.309 16554755,11805837 P40547 P25569 VID28 GID7 0.236 11805837 P47079 P25569 CCT8 GID7 0.126 11805837 Q12508 P25569 RMD5 GID7 0.236 11805837 P25569 P17255 GID7 VMA1 0.236 11805837 P25569 P19882 GID7 HSP60 0.126 11805837 Q02630 P25569 NUP116 GID7 0.236 11283351 Q02732 P25569 CTF19 GID7 0.236 11805837 Q03010 P25569 UME1 GID7 0.236 11805837 Q07657 P25569 SHS1 GID7 0.332 11805837