PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RPL1A TUP1 10688190 mint,intact,dip exp SSC1 TUP1 11805837 dip exp TUP1 NRG1 21552514 biogrid exp TUP1 DYN1 22875988 biogrid exp TEF1, TEF2 TUP1 16429126 intact exp NOT3 TUP1 22875988 biogrid exp LEU2 TUP1 11805837 dip exp TUP1 SSY5 11805837 biogrid,intact,dip exp TUP1 NSE4 10688190,14690591 mint,intact,dip exp TUP1 SSB2 23332755,19536198 biogrid,intact exp TUP1 KIN3 22875988 biogrid exp TUP1 STP22 22875988 biogrid exp HTA1 TUP1 i2d exp TUP1 NUT2 16758199 biogrid exp SBP1 TUP1 23222640 biogrid exp TUP1 CIN5 21552514 biogrid exp TUP1 CDC48 16554755 biogrid,i2d,mint,intact exp TUP1 NCA2 22875988 biogrid exp TUP1 SSE1 19536198 intact exp ENO1 TUP1 11805837 dip exp TUP1 HDA3 11172717 intact exp TUP1 YAP7 25732006 biogrid exp CET1 TUP1 12637515 biogrid exp TUP1 NNF2 22875988 biogrid exp TUP1 HSP78 19536198 intact exp TUP1 SMT3 15590687 biogrid exp TUP1 GAL11 22156212 biogrid exp UBI4 TUP1 21070969 biogrid exp TUP1 LAA1 22875988 biogrid exp TUP1 YAF9 22875988 biogrid exp TUP1 KEL2 22875988 biogrid exp TUP1 RGR1 11470794 biogrid exp TUP1 THI21 11805837 dip exp TUP1 PRS1 11297736 biogrid exp TUP1 CLU1 11805837 biogrid,intact,dip exp TUP1 SPA2 22875988 biogrid exp TUP1 PUF3 23409723 biogrid exp TUP1 IQG1 22875988 biogrid exp TUP1 SOR2 18467557 biogrid,i2d,mint,intact exp TUP1 HUG1 10688190 intact exp TUP1 DOA1 16554755 biogrid,i2d,mint,intact exp TUP1 KOG1 22875988 biogrid exp TUP1 CTR9 22875988 biogrid exp TUP1 ABF2 16429126 intact exp HMLALPHA2 TUP1 9315661 biogrid exp TUP1 SIN4 11470794 biogrid exp TUP1 MMR1 22875988 biogrid exp TUP1 ERP3 22875988 biogrid exp Uncharacterized protein YOR304C-A TUP1 22875988 biogrid exp TUP1 SPC72 22875988 biogrid exp TUP1 BFA1 16554755 intact exp TUP1 Uncharacterized protein YEL043W 22875988 biogrid exp MYO1 TUP1 22875988 biogrid exp TUP1 Uncharacterized protein YPR117W 22875988 biogrid exp HSP26 TUP1 11805837 dip exp TUP1 YAP6 21552514 biogrid exp TUP1 YKE2 22875988 biogrid exp HMRA2 TUP1 9315661 i2d,dip exp TUP1 NUF2 22875988 biogrid exp TUP1 CTF19 22875988 biogrid exp TUP1 SPH1 11805837 biogrid,intact,dip exp GCD2 TUP1 11805837 biogrid,mint,intact,dip exp TUP1 SIZ1 23712011 biogrid exp TUP1 GYP5 22875988 biogrid exp HSP82 TUP1 19536198 intact exp TUP1 SNF7 22875988 biogrid exp TUP1 MED2 11470794 biogrid exp TUP1 YET3 22875988 biogrid exp TUP1 YTA6 22875988 biogrid exp TUP1 YKT6 22875988 biogrid exp TUP1 SIN3 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred ABP1 TUP1 11805837, 23023127 biogrid,mint,intact,dip exp, pred TUP1 SSN8 11226276, 23023127 biogrid exp, pred SSA1 TUP1 19536198, 23023127 intact exp, pred TUP1 SKO1 11230135,11500510, 23023127 biogrid,dip exp, pred SSA2 TUP1 16429126,19536198, 23023127 intact exp, pred TUP1 SSN3 17689156,11226276, 23023127 biogrid exp, pred TUP1 SRB5 11226276, 23023127 biogrid exp, pred HHF1, HHF2 TUP1 8675011, 23023127 biogrid,dip exp, pred SSB1 TUP1 16429126,19536198,11805837, 23023127 intact,dip exp, pred CYC8 TUP1 16429126,11095729,14525981,18467557,8008070,11805837,11525400,9111019,2038333,21552514,22707714,11069890,17634984,8943325,10722750,10802055,10722672,10821179, 23023127 biogrid,i2d,mint,intact,dip exp, pred TUP1 HOS1 14525981, 23023127 biogrid,intact exp, pred TUP1 SKN7 21552514, 23023127 biogrid exp, pred NHP6B TUP1 11525400,11095729, 23023127 biogrid exp, pred TUP1 ECM10 11805837, 23023127 biogrid,intact,dip exp, pred TUP1 CDC73 11525400, 23023127 biogrid exp, pred TUP1 PHD1 21552514, 23023127 biogrid exp, pred TUP1 RFX1 16107689,9741624, 23023127 biogrid,i2d,intact exp, pred TUP1 PGD1 10722672,11470794, 23023127 biogrid,intact exp, pred TUP1 MET30 14690591, 23023127 intact exp, pred TUP1 SRB7 11118219,11470794, 23023127 biogrid exp, pred TUP1 HHT1, HHT2 8675011, 23023127 biogrid,dip exp, pred TUP1 TUP1 11967834,10722750,22707714,22875988, 23023127 biogrid,dip exp, pred TUP1 HDA1 11172717,21651791, 23023127 biogrid,intact,dip exp, pred TUP1 RPD3 14525981,11069890, 23023127 biogrid,i2d,intact exp, pred TUP1 TFB1 23023127 pred TUP1 SPT8 23023127 pred TUP1 MATALPHA2 23023127 pred TUP1 RSC8 23023127 pred TUP1 SCS2 23023127 pred TUP1 HAT2 23023127 pred TUP1 ASC1 23023127 pred TUP1 ISW1 23023127 pred TUP1 MOT2 23023127 pred TUP1 DOT6 23023127 pred TUP1 PFS2 23023127 pred TUP1 TAF5 23023127 pred TUP1 CAC2 23023127 pred TUP1 CSM1 23023127 pred TUP1 EGD2 23023127 pred TUP1 CHD1 23023127 pred TUP1 UBI4 23023127 pred TUP1 HIR1 23023127 pred TUP1 MRN1 23023127 pred TUP1 HHO1 23023127 pred HTB2 TUP1 23023127 pred TUP1 CBF1 23023127 pred TUP1 SNF2 23023127 pred TUP1 DSK2 23023127 pred HTB1 TUP1 23023127 pred TUP1 CUE5 23023127 pred TUP1 PUB1 23023127 pred TUP1 TIF34 23023127 pred TUP1 GSP1 23023127 pred TUP1 RSC2 23023127 pred TUP1 GID7 23023127 pred MSI1 TUP1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P16649 - 11805837 - C 7 P16649 - 11805826 - C 20 P16649 - 8943325 - C 5 P16649 - 8943325 - C 5 P16649 - 8943325 - C 5 P16649 - 8943325 - C 5 P16649 P11746 - 1739976 - X 2 P16649 - 11805837 - C 6 P16649 - 11805837 - C 6 P48743 P16649 - 9741624 - X 2 P32561 P16649 - 14525981 - X 2 P14922 P16649 - 11805837 - X 2 P14922 P16649 - 1739976 - X 2 P14922 P16649 - 8943325 - X 2 P25042 P16649 - 7565763 - X 2 P22579 P16649 affinity chromatography technology 16429126 physical association X 2 P22579 P16649 affinity chromatography technology 11805826 physical association X 2 O13297 P16649 affinity chromatography technology 12637515 physical association X 2 O13297 P16649 pull down 12637515 direct interaction X 2 P32259 P16649 affinity chromatography technology 11470794 physical association X 2 P53253 P16649 two hybrid 22875988 direct interaction X 2 P0CG63 P16649 affinity chromatography technology 23749301 physical association X 2 P0CG63 P16649 pull down 21070969 direct interaction X 2 P0CG63 P16649 affinity chromatography technology 21427232 physical association X 2 P32618 P16649 two hybrid 22875988 direct interaction X 2 P32618 P16649 two hybrid 22875988 direct interaction X 2 P16649 P16649 x-ray crystallography 22707714 association X 2 P16649 P16649 two hybrid 22875988 direct interaction X 2 P16649 P33895 two hybrid 22875988 direct interaction X 2 P16649 P40328 two hybrid 22875988 direct interaction X 2 P16649 P39073 affinity chromatography technology 11226276 physical association X 2 P16649 P39073 affinity chromatography technology 11226276 physical association X 2 P16649 Q12124 affinity chromatography technology 11470794 physical association X 2 P16649 P02309 pull down 8675011 direct interaction X 2 P16649 Q12306 affinity chromatography technology 15292183 physical association X 2 P16649 Q12306 affinity chromatography technology 15590687 physical association X 2 P16649 P16649 unspecified method 11967834 direct interaction X 2 P16649 P16649 pull down 10722750 direct interaction X 2 P16649 Q12306 affinity chromatography technology 23712011 physical association X 2 P16649 Q12306 affinity chromatography technology 23935535 physical association X 2 P16649 Q12306 affinity chromatography technology 24074957 physical association X 2 P16649 P39073 two hybrid 17689156 direct interaction X 2 P16649 Q12306 affinity chromatography technology 15326169 physical association X 2 P16649 Q12306 affinity chromatography technology 15166219 physical association X 2 P16649 P39987 affinity chromatography technology 11805837 physical association X 2 P16649 Q12306 affinity chromatography technology 15542864 physical association X 2 P16649 Q12306 affinity chromatography technology 15542864 physical association X 2 P16649 Q12306 affinity chromatography technology 22025676 physical association X 2 P16649 P19659 imaging technique 22156212 colocalization X 2 P36015 P16649 two hybrid 22875988 direct interaction X 2 Q07451 P16649 two hybrid 22875988 direct interaction X 2 Q03125 P16649 affinity chromatography technology 21552514 physical association X 2 Q06213 P16649 two hybrid 16758199 direct interaction X 2 P08964 P16649 two hybrid 22875988 direct interaction X 2 Q06697 P16649 protein complementation assay 11525400 direct interaction X 2 P38889 P16649 affinity chromatography technology 21552514 physical association X 2 P32585 P16649 affinity chromatography technology 11226276 physical association X 2 P39526 P16649 two hybrid 22875988 direct interaction X 2 P25604 P16649 two hybrid 22875988 direct interaction X 2 P89105 P16649 two hybrid 22875988 direct interaction X 2 P15891 P16649 affinity chromatography technology 11805837 physical association X 2 P38873 P16649 two hybrid 22875988 direct interaction X 2 P38873 P16649 two hybrid 22875988 direct interaction X 2 P50090 P16649 two hybrid 22875988 direct interaction X 2 P40150 P16649 biochemical 23332755 association X 2 P39723 P16649 two hybrid 22875988 direct interaction X 2 P53973 P16649 pull down 11172717 direct interaction X 2 P53973 P16649 imaging technique 21651791 colocalization X 2 Q03690 P16649 affinity chromatography technology 11805837 physical association X 2 P36022 P16649 two hybrid 22875988 direct interaction X 2 Q06116 P16649 two hybrid 22875988 direct interaction X 2 P52553 P16649 two hybrid 22875988 direct interaction X 2 P19263 P16649 affinity chromatography technology 11470794 physical association X 2 P11633 P16649 pull down 11095729 direct interaction X 2 P11633 P16649 protein complementation assay 11095729 direct interaction X 2 P11633 P16649 protein complementation assay 11525400 direct interaction X 2 Q12280 P16649 two hybrid 22875988 direct interaction X 2 P47002 P16649 affinity chromatography technology 11805837 physical association X 2 P32895 P16649 pull down 11297736 direct interaction X 2 P32895 P16649 protein complementation assay 11297736 direct interaction X 2 Q12214 P16649 affinity chromatography technology 14525981 physical association X 2 Q06324 P16649 two hybrid 22875988 direct interaction X 2 P39929 P16649 two hybrid 22875988 direct interaction X 2 P22209 P16649 two hybrid 22875988 direct interaction X 2 P22209 P16649 two hybrid 22875988 direct interaction X 2 P16649 affinity chromatography technology 11805837 physical association X 2 P16649 P53930 two hybrid 22875988 direct interaction X 2 P16649 Q12344 two hybrid 22875988 direct interaction X 2 P16649 P23201 two hybrid 22875988 direct interaction X 2 P16649 Q12344 two hybrid 22875988 direct interaction X 2 P16649 P40356 affinity chromatography technology 11470794 physical association X 2 P16649 P40356 pull down 10722672 direct interaction X 2 P16649 Q04195 affinity chromatography technology 23712011 physical association X 2 P16649 Q04195 affinity chromatography technology 23712011 physical association X 2 P16649 P25694 affinity chromatography technology 16554755 physical association X 2 P16649 P12754 affinity chromatography technology 11805837 physical association X 2 P47822 P16649 affinity chromatography technology 11470794 physical association X 2 P47822 P16649 pull down 11118219 direct interaction X 2 P47822 P16649 two hybrid 11118219 direct interaction X 2 P47821 P16649 affinity chromatography technology 11226276 physical association X 2 Q12374 P16649 two hybrid 22875988 direct interaction X 2 P06102 P16649 two hybrid 22875988 direct interaction X 2 P48743 P16649 pull down 9741624 direct interaction X 2 P48743 P16649 pull down 16107689 direct interaction X 2 P32561 P16649 affinity chromatography technology 14525981 physical association X 2 P32561 P16649 affinity chromatography technology 11069890 physical association X 2 P61830 P16649 pull down 8675011 direct interaction X 2 P40917 P16649 affinity chromatography technology 21552514 physical association X 2 P0CY08 P16649 pull down 9315661 direct interaction X 2 P0CY08 P16649 two hybrid 9315661 direct interaction X 2 P0CY08 P16649 pull down 9315661 direct interaction X 2 P14922 P16649 pull down 22707714 direct interaction X 2 P14922 P16649 affinity chromatography technology 2038333 physical association X 2 P14922 P16649 affinity chromatography technology 2038333 physical association X 2 P14922 P16649 affinity chromatography technology 11069890 physical association X 2 P14922 P16649 pull down 10722750 direct interaction X 2 P14922 P16649 pull down 10722672 direct interaction X 2 P14922 P16649 two hybrid 10802055 direct interaction X 2 P14922 P16649 pull down 8008070 direct interaction X 2 P14922 P16649 pull down 8943325 direct interaction X 2 P14922 P16649 affinity chromatography technology 8943325 physical association X 2 P14922 P16649 biochemical 10821179 colocalization X 2 P14922 P16649 biochemical 9111019 colocalization X 2 P14922 P16649 pull down 17634984 direct interaction X 2 P14922 P16649 protein complementation assay 18467557 direct interaction X 2 P14922 P16649 protein complementation assay 11095729 direct interaction X 2 P14922 P16649 protein complementation assay 11525400 direct interaction X 2 P14922 P16649 affinity chromatography technology 21552514 physical association X 2 P14922 P16649 affinity chromatography technology 21552514 physical association X 2 P14922 P16649 affinity chromatography technology 11805837 physical association X 2 O14468 P16649 two hybrid 22875988 direct interaction X 2 Q03935 P16649 affinity chromatography technology 21552514 physical association X 2 Q02100 P16649 affinity chromatography technology 11500510 physical association X 2 Q02100 P16649 affinity chromatography technology 11230135 physical association X 2 Q07786 P16649 protein complementation assay 18467557 direct interaction X 2 Q12403 P16649 two hybrid 22875988 direct interaction X 2 P36093 P16649 affinity chromatography technology 21552514 physical association X 2 P36037 P16649 affinity chromatography technology 16554755 physical association X 2 Q02732 P16649 two hybrid 22875988 direct interaction X 2 P16649 anti tag coimmunoprecipitation 11805837 - C 7 P16649 anti tag coimmunoprecipitation 11805837 - C 16 P16649 anti tag coimmunoprecipitation 11805837 - C 21 P16649 tandem affinity purification 11805826 - C 20 P16649 anti tag coimmunoprecipitation 11805837 - C 6 P22579 P16649 tandem affinity purification 11805826 physical association X 2 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P16649 P15992 anti tag coimmunoprecipitation 11805837 physical association X 2 P16649 P0CY12 biochemical 7995523 direct interaction X 2 P16649 P0CY12 genetic interference 7995523 direct interaction X 2 P16649 P0CY12 affinity chromatography technology 9315661 direct interaction X 2 P16649 P0CY12 x-ray crystallography 9315661 direct interaction X 2 P16649 P39987 anti tag coimmunoprecipitation 11805837 physical association X 2 P16649 P16649 molecular sieving 8943325 physical association Y 1 P16649 P16649 cosedimentation through density gradient 8943325 physical association Y 1 P16649 P16649 biophysical 8943325 physical association Y 1 P16649 P16649 lambda repressor two hybrid 11967834 physical association Y 1 P16649 P16649 biophysical 10722750 physical association Y 1 P16649 P02309 filter binding 8675011 physical association X 2 P16649 P43124 two hybrid 10688190 physical association X 2 P15891 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P53973 P16649 coimmunoprecipitation 11172717 physical association X 2 Q03690 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P16649 anti tag coimmunoprecipitation 11805837 - C 6 P16649 anti tag coimmunoprecipitation 11805837 - C 12 P16649 inferred by author 11805826 physical association C 31 P11484 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P16649 P12754 anti tag coimmunoprecipitation 11805837 physical association X 2 P16649 P0CX43 two hybrid 10688190 physical association X 2 P00924 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 Q08975 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P04173 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P61830 P16649 filter binding 8675011 physical association X 2 P14922 P16649 affinity chromatography technology 9111019 direct interaction X 2 P14922 P16649 surface plasmon resonance 10722750 direct interaction X 2 P14922 P16649 molecular sieving 9111019 direct interaction X 2 P14922 P16649 biochemical 9111019 direct interaction X 2 P14922 P16649 biophysical 9111019 direct interaction X 2 P14922 P16649 anti tag coimmunoprecipitation 11805837 direct interaction X 2 P14922 P16649 experimental interaction detection 2038333 direct interaction X 2 P14922 P16649 experimental interaction detection 9111019 direct interaction X 2 P14922 P16649 coimmunoprecipitation 2038333 direct interaction X 2 Q02100 P16649 coimmunoprecipitation 11230135 physical association X 2 Q02100 P16649 coimmunoprecipitation 11500510 physical association X 2 P0CS90 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P16649 anti tag coimmunoprecipitation 11805837 association C 7 P16649 inferred by author 16429126 physical association C 37 P16649 anti tag coimmunoprecipitation 11805837 association C 6 P16649 inferred by author 16429126 physical association C 35 P16649 inferred by author 16554755 association C 22 P16649 pull down 10722672 association C 3 P39014 P16649 two hybrid array 14690591 physical association X 2 P16649 P43124 two hybrid 10688190 physical association X 2 P16649 P43124 two hybrid array 14690591 physical association X 2 P16649 P33416 tandem affinity purification 19536198 association X 2 P02829 P16649 tandem affinity purification 19536198 association X 2 P40150 P16649 tandem affinity purification 19536198 association X 2 P53973 P16649 pull down 11172717 physical association X 2 P16649 tandem affinity purification 16429126 association C 5 P16649 tandem affinity purification 11805826 association C 21 P16649 anti tag coimmunoprecipitation 11805837 association C 6 P16649 tandem affinity purification 16429126 association C 26 P16649 pull down 9741624 association C 3 P10592 P16649 tandem affinity purification 19536198 association X 2 P32589 P16649 tandem affinity purification 19536198 association X 2 Q12214 P16649 anti tag coimmunoprecipitation 14525981 physical association X 2 P11484 P16649 tandem affinity purification 19536198 association X 2 P16649 Q6Q5K6 two hybrid 10688190 physical association X 2 P16649 P0CX43 two hybrid 10688190 physical association X 2 P16649 P40356 two hybrid 10722672 physical association X 2 P16649 P40356 pull down 10722672 physical association X 2 P16649 Q06623 pull down 11172717 physical association X 2 P16649 P25694 tandem affinity purification 16554755 physical association X 2 P48743 P16649 pull down 9741624 physical association X 2 P32561 P16649 anti bait coimmunoprecipitation 11069890 physical association X 2 P32561 P16649 anti bait coimmunoprecipitation 14525981 physical association X 2 P14922 P16649 anti bait coimmunoprecipitation 11069890 physical association X 2 P14922 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P14922 P16649 anti bait coimmunoprecipitation 14525981 physical association X 2 P14922 P16649 dihydrofolate reductase reconstruction 18467557 physical association X 2 P10591 P16649 tandem affinity purification 19536198 association X 2 Q07786 P16649 dihydrofolate reductase reconstruction 18467557 physical association X 2 P36037 P16649 tandem affinity purification 16554755 physical association X 2 P16649 mass spectrometry studies of complexes 11805837 - C 8 P16649 mass spectrometry studies of complexes 11805826 - C 35 P16649 mass spectrometry studies of complexes 11805837 - C 7 P16649 mass spectrometry studies of complexes 11805837 - C 7 P16649 mass spectrometry studies of complexes 11805837 - C 7 P0CY08 P16649 interaction detection method - - X 2 P0CY08 P16649 coimmunoprecipitation - - X 2 P0CY08 P16649 interaction detection method - - X 2 P14922 P16649 affinity chromatography technology 9111019 - X 2 P14922 P16649 confirmational text mining - - X 2

PPI - HINT Gene A Gene B PMID Method Quality O14468 TUP1 22875988 0018 HT HHF1|HHF2 TUP1 8675011,8675011 0096,0049 LC NOT3 TUP1 22875988 0018 HT MYO1 TUP1 22875988 0018 HT RPL1A TUP1 10688190 0018 HT MATALPHA2 TUP1 9315661,9315661 0096,0018 LC HMLALPHA2 TUP1 9315661,9315661 0096,0018 LC MATA2 TUP1 7995523,9315661,9315661 0401,0114,0004 LC NHP6B TUP1 11095729,11095729,11525400 0096,0090,0090 LC CYC8 TUP1 8943325,10821179,18467557,9111019,8943325,9111019,8943325,2038333,11095729,8943325,9111019,10722750,9111019,10722750,2038333,11525400,10802055,18467557,9111019,8943325,2038333 0019,0401,0111,0071,0096,0004,0004,0019,0090,0045,0045,0107,0401,0096,0004,0090,0018,0090,0013,0029,0045 LC,HT TUP1 TUP1 10722750,10722750,8943325,8943325,22707714,8943325,11967834,22875988,10856245 0096,0013,0013,0029,0114,0071,0655,0018,0114 LC,HT TUP1 KIN3 22875988 0018 HT TUP1 SPA2 22875988 0018 HT TUP1 STP22 22875988 0018 HT TUP1 RPD3 14525981,14525981,14525981 0019,0006,0004 LC TUP1 P32618 22875988 0018 HT TUP1 PRS1 11297736,11297736 0090,0096 LC TUP1 NUF2 22875988 0018 HT TUP1 YKT6 22875988 0018 HT TUP1 DYN1 22875988 0018 HT TUP1 KOG1 22875988 0018 HT TUP1 MET30 14690591 0397 LC TUP1 SSN3 17689156 0018 LC TUP1 LAA1 22875988 0018 HT TUP1 SPC72 22875988 0018 HT TUP1 SNF7 22875988 0018 HT TUP1 SSB2 23332755 0401 LC TUP1 YTA6 22875988 0018 HT TUP1 PGD1 10722672,10722672 0096,0018 LC TUP1 NSE4 10688190,14690591 0018,0397 HT,LC TUP1 SRB7 11118219,11118219 0096,0018 LC TUP1 KEL2 22875988 0018 HT TUP1 YKE2 22875988 0018 HT TUP1 NNF2 22875988 0018 HT TUP1 YAF9 22875988 0018 HT TUP1 HDA1 11172717,11172717 0019,0096 LC TUP1 HHT1|HHT2 8675011,8675011 0096,0049 LC TUP1 CTR9 22875988 0018 HT TUP1 SKO1 11500510,11500510,11230135,11230135 0004,0019,0019,0004 LC TUP1 CTF19 22875988 0018 HT TUP1 Q06116 22875988 0018 HT TUP1 NUT2 16758199 0018 LC TUP1 MMR1 22875988 0018 HT TUP1 CDC73 11525400 0090 LC TUP1 YET3 22875988 0018 HT TUP1 SOR2 18467557,18467557 0111,0090 HT TUP1 IQG1 22875988 0018 HT TUP1 GYP5 22875988 0018 HT TUP1 NCA2 22875988 0018 HT TUP1 ERP3 22875988 0018 HT TUP1 HUG1 10688190 0018 HT CET1 TUP1 12637515,12637515 0096,0004 LC ENO1 TUP1 11805837 0007 HT HHF1|HHF2 TUP1 8675011,8675011 0096,0049 LC HSP82 TUP1 19536198 0676 HT TEF1|TEF2 TUP1 16429126 0676 HT LEU2 TUP1 11805837 0007 HT UBI4 TUP1 21070969,21070969 0004,0096 LC SSC1 TUP1 11805837 0007 HT MATALPHA2 TUP1 9315661,9315661 0096,0018 LC HMLALPHA2 TUP1 9315661,9315661 0096,0018 LC MATA2 TUP1 7995523,9315661,9315661 0401,0114,0004 LC SSA1 TUP1 19536198 0676 HT SSA2 TUP1 19536198,16429126 0676,0676 HT SSB1 TUP1 19536198,16429126,11805837 0676,0676,0007 HT NHP6B TUP1 11095729,11095729 0096,0090 LC GCD2 TUP1 11805837,11805837 0004,0007 HT CYC8 TUP1 8943325,10821179,9111019,26257283,21552514,8943325,8008070,9111019,8943325,11069890,2038333,17634984,11805837,22707714,8943325,16429126,9111019,10722672,10722750,11805837,9111019,10722750,2038333,11069890,9111019,14525981,8943325,2038333 0019,0401,0071,0004,0004,0096,0096,0004,0004,0004,0019,0096,0004,0096,0045,0676,0045,0096,0107,0007,0401,0096,0004,0006,0013,0006,0029,0045 LC,HT ABP1 TUP1 11805837,11805837 0004,0007 HT HSP26 TUP1 11805837 0007 HT TUP1 TUP1 10722750,10722750 0096,0013 LC TUP1 RGR1 11470794 0004 LC TUP1 GAL11 22156212 0428 LC TUP1 SIN3 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT TUP1 CDC48 16554755,16554755 0676,0004 HT TUP1 SIN4 11470794 0004 LC TUP1 RPD3 11069890,14525981,14525981,11069890,14525981 0004,0019,0006,0006,0004 LC TUP1 SRB5 11226276 0004 LC TUP1 SSE1 19536198 0676 HT TUP1 PRS1 11297736,11297736 0090,0096 LC TUP1 HSP78 19536198 0676 HT TUP1 DOA1 16554755,16554755 0676,0004 HT TUP1 PHD1 21552514 0004 LC TUP1 SKN7 21552514 0004 LC TUP1 SSN3 11226276 0004 LC TUP1 ECM10 11805837,11805837 0004,0007 HT TUP1 SSB2 19536198,23332755 0676,0401 HT,LC TUP1 PGD1 11470794,10722672,10722672 0004,0096,0018 LC TUP1 CIN5 21552514 0004 LC TUP1 SSY5 11805837,11805837 0004,0007 HT TUP1 BFA1 16554755 0363 HT TUP1 SSN8 11226276 0004 LC TUP1 SRB7 11470794,11118219,11118219 0004,0096,0018 LC TUP1 RFX1 16107689,9741624,9741624 0096,0004,0096 LC TUP1 HDA1 11172717,11172717,21651791 0019,0096,0428 LC TUP1 HHT1|HHT2 8675011,8675011 0096,0049 LC TUP1 SKO1 11500510,11500510,11230135,11230135 0004,0019,0019,0004 LC TUP1 ABF2 16429126 0363 HT TUP1 NRG1 21552514 0004 LC TUP1 CLU1 11805837,11805837 0004,0007 HT TUP1 YAP6 21552514 0004 LC TUP1 SIZ1 23712011 0004 LC TUP1 SPH1 11805837,11805837 0004,0007 HT TUP1 MMS22 26849847 0004 LC TUP1 HDA3 11172717 0096 LC TUP1 YAP7 25732006 0004 LC TUP1 THI21 11805837 0007 HT TUP1 MED2 11470794 0004 LC TUP1 HOS1 14525981,14525981 0007,0004 LC TUP1 SMT3 15292183,15542864,15590687,22025676,15326169,15166219 0004,0004,0004,0004,0004,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P22579 P16649 SIN3 TUP1 0.286 11805826,16429126 P16649 P15891 TUP1 ABP1 0.286 11805837 P16649 P15992 TUP1 HSP26 0.126 11805837 Q12306 P16649 SMT3 TUP1 0.126 15590687 P16649 P0CG48 TUP1 UBC 0.126 23801757 P16649 P0CG63 TUP1 UBI4 0.309 21070969 P16649 P0CY08 TUP1 MATALPHA2 0.309 9315661 P16649 P0CY09 TUP1 HMLALPHA2 0.309 9315661 P16649 P10080 TUP1 SBP1 0.126 23222640 P16649 P10591 TUP1 SSA1 0.126 19536198 P16649 P00924 TUP1 ENO1 0.126 11805837 P16649 P12754 TUP1 GCD2 0.286 11805837 P16649 P04173 TUP1 LEU2 0.126 11805837 P16649 P11633 TUP1 NHP6B 0.523 11095729,11525400 P16649 P16649 TUP1 TUP1 0.554 11967834,22707714,10722750,8943325 P36037 P16649 DOA1 TUP1 0.236 16554755 P48743 P16649 RFX1 TUP1 0.523 9741624,16107689 P40150 P16649 SSB2 TUP1 0.236 23332755,19536198 Q6B184 P16649 HMRA2 TUP1 0.354 7995523,9315661 P16649 P14922 TUP1 CYC8 0.996 18467557,10821179,11525400,11805837,26257283,9111019,17634984,21552514,10722672,11095729,10802055,2038333,22707714,16429126,8008070,10722750 P33416 P16649 HSP78 TUP1 0.126 19536198 P39987 P16649 ECM10 TUP1 0.236 11805837 P43124 P16649 NSE4 TUP1 0.309 10688190,14690591 P47113 P16649 BFA1 TUP1 0.126 16554755 P47822 P16649 SRB7 TUP1 0.309 11118219 P16649 O13297 TUP1 CET1 0.454 12637515 Q02100 P16649 SKO1 TUP1 0.261 11230135,11500510 Q02486 P16649 ABF2 TUP1 0.126 16429126 Q06160 P16649 SPH1 TUP1 0.236 11805837 Q03125 P16649 NRG1 TUP1 0.21 21552514 P16649 P02309 TUP1 HHF2 0.309 8675011 P16649 P12398 TUP1 SSC1 0.126 11805837 P16649 P10592 TUP1 SSA2 0.236 16429126,19536198 P16649 P02994 TUP1 TEF2 0.126 16429126 P16649 P02829 TUP1 HSP82 0.126 19536198 P61830 P16649 HHT2 TUP1 0.332 8675011 P16649 P11484 TUP1 SSB1 0.309 11805837,19536198,16429126 P19659 P16649 GAL11 TUP1 0.126 22156212 P53973 P16649 HDA1 TUP1 0.396 11172717,21651791 P32895 P16649 PRS1 TUP1 0.309 11297736 P32589 P16649 SSE1 TUP1 0.126 19536198 P25694 P16649 CDC48 TUP1 0.236 16554755 P39014 P16649 MET30 TUP1 0.126 14690591 P38889 P16649 SKN7 TUP1 0.21 21552514 P36093 P16649 PHD1 TUP1 0.21 21552514 P47002 P16649 SSY5 TUP1 0.21 11805837 P39073 P16649 SSN3 TUP1 0.309 17689156 P40356 P16649 PGD1 TUP1 0.309 10722672 P40917 P16649 CIN5 TUP1 0.21 21552514 P53030 P16649 RPL1B TUP1 0.21 10688190 Q03690 P16649 CLU1 TUP1 0.21 11805837 Q6Q5K6 P16649 HUG1 TUP1 0.183 10688190 Q04195 P16649 SIZ1 TUP1 0.236 23712011 Q03935 P16649 YAP6 TUP1 0.21 21552514 Q07786 P16649 SOR2 TUP1 0.286 18467557 Q06697 P16649 CDC73 TUP1 0.309 11525400 Q08182 P16649 YAP7 TUP1 0.21 25732006 Q08975 P16649 THI21 TUP1 0.126 11805837