PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ATP2 ABP1 11805837 dip exp ABP1 SDH4 11743162 mint exp ABP1 HUA2 11743162,11489916,10688190,11283351,18719252 biogrid,i2d,mint,intact,dip exp SSB1 ABP1 16429126 intact exp ABP1 UBC9 23712011 biogrid exp ABP1 Uncharacterized protein YCR099C 19841731 biogrid,mint,intact exp GAL1 ABP1 11805837 dip exp ABP1 RSC3 19841731 biogrid,mint,intact exp ABP1 Putative lipase YDR444W 19841731 mint,intact exp ABP1 STD1 19841731 biogrid,mint,intact exp ABP1 NAB2 19840948 biogrid exp ABP1 PEX14 i2d exp ABP1 SYT1 11743162 mint exp ABP1 TPP1 19841731 mint,intact exp CDC9 ABP1 14737190 i2d,mint,intact exp SSA2 ABP1 19536198 intact exp LAT1 ABP1 11805837 dip exp ABP1 YTA12 11743162 mint exp ABP1 Uncharacterized hydrolase YNR064C 19841731 mint,intact exp ABP1 ACF2 11743162 mint exp ABP1 HXT7 11805837 biogrid,mint,intact,dip exp SSC1 ABP1 11805837 dip exp ABP1 MTH1 19841731 biogrid,mint,intact exp ABP1 SEC16 11743162 mint exp ABP1 PXA1 23831759 biogrid exp ABP1 HUA1 11743162 mint exp LPD1 ABP1 11805837 dip exp SSA1 ABP1 23217712 intact exp ABP1 EAF1 11743162 mint exp ABP1 SSZ1 19536198 intact exp ABP1 AFT2 11743162 mint exp RPO31 ABP1 19841731 biogrid,mint,intact exp ABP1 RPN10 18757749 biogrid exp ABP1 INP52 11668184,19590096,19841731,11743162,15798181 biogrid,i2d,mint,intact,dip exp PGI1 ABP1 11805837 dip exp ABP1 PDR3 19841731 biogrid,mint,intact exp ABP1 ECM29 21321079 biogrid exp ABP1 CTH1 11743162 mint exp ABP1 RPN11 20170199,18757749 biogrid exp ABP1 SRO9 22271760 biogrid exp ABP1 GPI13 19841731 mint,intact exp SBP1 ABP1 23222640 biogrid exp RPO21 ABP1 11743162 mint exp FAS1 ABP1 11805837 dip exp CDC6 ABP1 11743162 mint exp ABP1 Uncharacterized protein YER158C 11743162 mint exp ABP1 TUP1 11805837, 23023127 biogrid,mint,intact,dip exp, pred ABP1 VTC3 19841731, 23023127 mint,intact exp, pred SPS1 ABP1 11805837, 23023127 biogrid,mint,intact,dip exp, pred ABP1 SLA1 11743162,18952899,19841731,11950888,8552082, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 PAC11 14737190, 23023127 i2d,mint,intact exp, pred ABP1 ARK1 19841731,20489023,11668184,11743162,14668868,19590096,17409071,14737190,18006656, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 RVS167 11743162,19841731,11489916,23267104,14737190,9190214,10388809, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 BZZ1 11743162, 23023127 mint exp, pred ABP1 LAS17 21035341, 23023127 biogrid exp, pred ABP1 MYO5 11668184,20647997, 23023127 i2d,mint,intact,dip exp, pred ABP1 AIM46 11805837, 23023127 biogrid,mint,intact,dip exp, pred ABP1 CHL1 19841731, 23023127 biogrid,mint,intact exp, pred ABP1 SAC6 8334302,15534003, 23023127 biogrid,i2d,dip exp, pred ABP1 BBC1 19841731, 23023127 mint,intact exp, pred ABP1 SCP1 19590096,19841731,17409071,14737190,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 SRV2 14680631,19841731,23267104,11206067,11668184,11743162,11489916,11950888,17409071,14737190,9190214,8552082, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 ARP2 11331312, 23023127 biogrid,dip exp, pred CDC28 ABP1 24374311, 23023127 biogrid exp, pred ABP1 HSL7 19841731, 23023127 biogrid,mint,intact exp, pred ABP1 LSG1 14737190, 23023127 i2d,mint,intact exp, pred ABP1 ABP1 11668184,15798181,8552082, 23023127 intact exp, pred ABP1 BSP1 19841731, 23023127 mint,intact exp, pred ABP1 LSB3 11743162,19841731,14737190, 23023127 biogrid,i2d,mint,intact exp, pred ABP1 SNX41 19841731, 23023127 mint,intact exp, pred ABP1 PRK1 11668184,19841731,11743162,14737190,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 HEL2 14737190, 23023127 i2d,mint,intact exp, pred ABP1 SLA2 23023127 i2d exp, pred ABP1 BCK1 11743162, 23023127 mint exp, pred ABP1 ACT1 3060468,16429126,11331312, 23023127 biogrid,i2d,intact,dip exp, pred ABP1 APP1 11668184,19841731,11743162,11489916,23267104,14737190,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 SNF2 11743162,19841731, 23023127 mint,intact exp, pred ABP1 AIM3 19841731, 23023127 mint,intact exp, pred ABP1 ARP3 11331312,11805837, 23023127 biogrid,mint,intact,dip exp, pred ABP1 PIN3 11743162,19841731, 23023127 mint,intact exp, pred ABP1 AIM21 11668184,11743162,19841731,14737190, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 HAL9 19841731, 23023127 biogrid,mint,intact exp, pred ABP1 HRR25 11805837, 23023127 biogrid,intact,dip exp, pred ABP1 LSB1 19841731, 23023127 mint,intact exp, pred ABP1 CHC1 15992543,11805837, 23023127 biogrid,dip exp, pred ABP1 MKK1 21118957, 23023127 biogrid exp, pred ABP1 CLA4 11743162,11489916,10688190, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 BEM3 19841731, 23023127 biogrid,mint,intact exp, pred ABP1 YSC84 11743162,19841731,14737190,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred ABP1 PEX13 23023127 pred ABP1 MYO2 23023127 pred ABP1 AIM7 23023127 pred ABP1 BOI2 23023127 pred ABP1 HSL1 23023127 pred ABP1 ARC15 23023127 pred ABP1 TWF1 23023127 pred ABP1 RVS161 23023127 pred ABP1 CDC1 23023127 pred ABP1 AKL1 23023127 pred ABP1 YCK2 23023127 pred ABP1 MYO3 23023127 pred ABP1 CDC12 23023127 pred ABP1 CAP1 23023127 pred PFY1 ABP1 23023127 pred ABP1 MDY2 23023127 pred ABP1 SYH1 23023127 pred ABP1 STE20 23023127 pred ABP1 PHO85 23023127 pred ABP1 ARC40 23023127 pred ABP1 BUD4 23023127 pred BIK1 ABP1 23023127 pred ABP1 ARP7 23023127 pred CAP2 ABP1 23023127 pred ABP1 COF1 23023127 pred ABP1 END3 23023127 pred ABP1 YCK1 23023127 pred ABP1 CRN1 23023127 pred ABP1 PKC1 23023127 pred ABP1 GCS1 23023127 pred ABP1 PAN1 23023127 pred ABP1 ARC19 23023127 pred ABP1 BEM1 23023127 pred CDC25 ABP1 23023127 pred ABP1 TPM1 23023127 pred ABP1 GTS1 23023127 pred ABP1 ENT2 23023127 pred FUS1 ABP1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P15891 - 11805837 - C 7 P15891 - 11805837 - C 3 P15891 - 11805837 - C 56 P40494 P15891 - 11743162 - X 2 P40494 P15891 - 14737190 - X 2 P40494 P15891 - 11668184 - X 2 P53145 P15891 - 14737190 - X 2 P15891 P32793 - 14737190 - X 2 P15891 P32793 - 14737190 - X 2 P15891 P32793 - 14737190 - X 2 P15891 P39743 - 10388809 - X 2 P15891 P39743 - 14737190 - X 2 P15891 P32790 - 11950888 - X 2 P15891 - 14737190 - X 2 P15891 - 14737190 - X 2 P15891 - 14737190 - X 2 P15891 P53112 - 14668868 - X 2 P15891 P39743 - 9057315 - X 2 P15891 P39743 - 7719850 - X 2 P15891 P39743 - 11489916 - X 2 P15891 P60010 - 3060468 - X 2 P15891 P48562 - 11489916 - X 2 P15891 P40960 - 14737190 - X 2 P15891 P04819 - 14737190 - X 2 P15891 P50942 - 11668184 - X 2 P15891 P50942 - 11743162 - X 2 P53933 P15891 - 11805837 - X 2 P53933 P15891 - 11743162 - X 2 P53933 P15891 - 11668184 - X 2 P53933 P15891 - 11489916 - X 2 P15891 - 11805837 - C 4 P15891 - 11805837 - C 9 P53974 P15891 - 11668184 - X 2 P53974 P15891 - 14737190 - X 2 P53974 P15891 - 11743162 - X 2 P53974 P15891 - 14737190 - X 2 P17555 P15891 - 8552082 - X 2 P17555 P15891 - 11489916 - X 2 P17555 P15891 - 14737190 - X 2 P17555 P15891 - 11743162 - X 2 P17555 P15891 - 11950888 - X 2 Q12134 P15891 - 11743162 - X 2 Q12134 P15891 - 11283351 - X 2 Q12134 P15891 - 11489916 - X 2 P15891 Q04439 - 11668184 - X 2 P15891 P40563 - 14737190 - X 2 P15891 P40563 - 11668184 - X 2 P15891 P40563 - 14737190 - X 2 P15891 Q08873 - 14737190 - X 2 P15891 Q05580 - 14737190 - X 2 Q12180 P15891 two hybrid 19841731 direct interaction X 2 P0CG63 P15891 affinity chromatography technology 23749301 physical association X 2 P0CG63 P15891 affinity chromatography technology 17644757 physical association X 2 P0CG63 P15891 affinity chromatography technology 23793018 physical association X 2 P0CG63 P15891 affinity chromatography technology 12872131 physical association X 2 P0CG63 P15891 affinity chromatography technology 21427232 physical association X 2 P0CG63 P15891 affinity chromatography technology 22106047 physical association X 2 P40494 P15891 affinity chromatography technology 11668184 physical association X 2 P40494 P15891 unspecified method 14737190 direct interaction X 2 P40494 P15891 affinity chromatography technology 14737190 physical association X 2 P40494 P15891 two hybrid 11743162 direct interaction X 2 P40494 P15891 two hybrid 19841731 direct interaction X 2 P40494 P15891 affinity chromatography technology 11805837 physical association X 2 P38274 P15891 two hybrid 19841731 direct interaction X 2 P15891 P32790 affinity chromatography technology 11950888 physical association X 2 P15891 P32790 affinity chromatography technology 11950888 physical association X 2 P15891 P32381 affinity chromatography technology 11331312 physical association X 2 P15891 P32790 fluorescent resonance energy transfer 11950888 direct interaction X 2 P15891 P39743 two hybrid 10388809 direct interaction X 2 P15891 P48562 two hybrid 11489916 direct interaction X 2 P15891 P39743 two hybrid 11489916 direct interaction X 2 P15891 P32599 imaging technique 15534003 colocalization X 2 P15891 P50942 two hybrid 11743162 direct interaction X 2 P15891 P60010 imaging technique 3060468 colocalization X 2 P15891 P50942 unspecified method 11668184 direct interaction X 2 P15891 P50942 imaging technique 15798181 colocalization X 2 P15891 P50942 affinity chromatography technology 15798181 physical association X 2 P15891 P50623 affinity chromatography technology 23712011 physical association X 2 P15891 Q12306 affinity chromatography technology 23935535 physical association X 2 P15891 P41909 protein complementation assay 23831759 direct interaction X 2 P15891 P60010 biochemical 11331312 colocalization X 2 P15891 P47117 biochemical 11331312 colocalization X 2 P15891 P32599 affinity chromatography technology 17200106 physical association X 2 P15891 P60010 affinity chromatography technology 17200106 physical association X 2 P15891 Q06440 affinity chromatography technology 17200106 physical association X 2 P15891 Q12230 affinity chromatography technology 17200106 physical association X 2 P15891 P32790 fluorescent resonance energy transfer 18952899 direct interaction X 2 P15891 P38886 affinity chromatography technology 18757749 physical association X 2 P15891 P43588 affinity chromatography technology 18757749 physical association X 2 P15891 P32873 two hybrid 19841731 direct interaction X 2 P15891 P33200 two hybrid 19841731 direct interaction X 2 P15891 Q02794 two hybrid 19841731 direct interaction X 2 P15891 P25657 two hybrid 19841731 direct interaction X 2 P15891 P43603 two hybrid 19841731 direct interaction X 2 P15891 P32793 two hybrid 19841731 direct interaction X 2 P15891 P50942 unspecified method 19590096 direct interaction X 2 P15891 P43588 affinity chromatography technology 20170199 physical association X 2 P15891 Q12306 affinity chromatography technology 15326169 physical association X 2 P15891 P32490 protein complementation assay 21118957 direct interaction X 2 P15891 Q12446 affinity chromatography technology 21035341 physical association X 2 P15891 Q12446 affinity chromatography technology 21035341 physical association X 2 P15891 P47117 affinity chromatography technology 11805837 physical association X 2 P15891 P16649 affinity chromatography technology 11805837 physical association X 2 P15891 P32793 affinity chromatography technology 11805837 physical association X 2 P15891 P38885 affinity chromatography technology 11805837 physical association X 2 P53933 P15891 two hybrid 11489916 direct interaction X 2 P53933 P15891 unspecified method 14737190 direct interaction X 2 P53933 P15891 affinity chromatography technology 14737190 physical association X 2 P53933 P15891 two hybrid 11743162 direct interaction X 2 P53933 P15891 unspecified method 11668184 direct interaction X 2 P53933 P15891 two hybrid 19841731 direct interaction X 2 P53933 P15891 affinity chromatography technology 11805837 physical association X 2 P53974 P15891 affinity chromatography technology 11668184 physical association X 2 P53974 P15891 unspecified method 14737190 direct interaction X 2 P53974 P15891 two hybrid 11743162 direct interaction X 2 P53974 P15891 unspecified method 18006656 direct interaction X 2 P53974 P15891 two hybrid 19841731 direct interaction X 2 P53974 P15891 unspecified method 19590096 direct interaction X 2 P53974 P15891 affinity chromatography technology 20489023 physical association X 2 P04051 P15891 two hybrid 19841731 direct interaction X 2 P17555 P15891 affinity chromatography technology 11950888 physical association X 2 P17555 P15891 pull down 9190214 direct interaction X 2 P17555 P15891 pull down 8552082 direct interaction X 2 P17555 P15891 two hybrid 11489916 direct interaction X 2 P17555 P15891 unspecified method 14737190 direct interaction X 2 P17555 P15891 unspecified method 11206067 direct interaction X 2 P17555 P15891 two hybrid 11743162 direct interaction X 2 P17555 P15891 biochemical 14680631 colocalization X 2 Q12134 P15891 two hybrid 11489916 direct interaction X 2 Q12134 P15891 two hybrid 11743162 direct interaction X 2 Q12134 P15891 two hybrid 18719252 direct interaction X 2 P15891 P40563 unspecified method 14737190 direct interaction X 2 P15891 Q08873 unspecified method 14737190 direct interaction X 2 P15891 Q08873 affinity chromatography technology 14737190 physical association X 2 P15891 P40563 affinity chromatography technology 14737190 physical association X 2 P15891 P22137 imaging technique 15992543 colocalization X 2 P15891 P25343 affinity chromatography technology 17200106 physical association X 2 P15891 P22516 two hybrid 19841731 direct interaction X 2 P15891 P35198 two hybrid 19841731 direct interaction X 2 P15891 Q06639 two hybrid 19841731 direct interaction X 2 P15891 Q08873 unspecified method 19590096 direct interaction X 2 P15891 P38737 affinity chromatography technology 21321079 physical association X 2 P15891 P29295 affinity chromatography technology 11805837 physical association X 2 P15891 P39004 affinity chromatography technology 11805837 physical association X 2 P15891 Q08873 affinity chromatography technology 11805837 physical association X 2 P15891 P08458 affinity chromatography technology 11805837 physical association X 2 P15891 anti tag coimmunoprecipitation 11805837 - C 7 P15891 anti tag coimmunoprecipitation 11805837 - C 4 P15891 anti tag coimmunoprecipitation 11805837 - C 3 P15891 anti tag coimmunoprecipitation 11805837 - C 74 P15891 anti tag coimmunoprecipitation 11805837 - C 16 P04385 P15891 anti tag coimmunoprecipitation 11805837 physical association X 2 P40494 P15891 two hybrid 11668184 physical association X 2 P40494 P15891 two hybrid 11743162 physical association X 2 P40494 P15891 coimmunoprecipitation 11668184 physical association X 2 P40494 P15891 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P09624 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P32381 affinity chromatography technology 11331312 physical association X 2 P15891 P60010 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P60010 biochemical 11331312 physical association X 2 P15891 P39743 experimental interaction detection 9190214 physical association X 2 P15891 P39743 genetic interference 10388809 physical association X 2 P15891 P39743 two hybrid 9190214 physical association X 2 P15891 P39743 two hybrid 11489916 physical association X 2 P15891 P39743 coimmunoprecipitation 9190214 physical association X 2 P15891 P50942 two hybrid 11743162 physical association X 2 P15891 P50942 phage display 11668184 physical association X 2 P15891 P47117 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P16649 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P32793 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P38885 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P32599 genetic interference 8334302 - X 2 P15891 P32599 genetic interference 8335689 - X 2 P15891 P32790 affinity chromatography technology 11950888 physical association X 2 P15891 P32790 fluorescent resonance energy transfer 11950888 physical association X 2 P15891 P32790 genetic interference 8552082 physical association X 2 P15891 P32790 coimmunoprecipitation 11950888 physical association X 2 P15891 P48562 two hybrid 11489916 physical association X 2 P15891 P48562 two hybrid 10688190 physical association X 2 P53933 P15891 two hybrid 11489916 physical association X 2 P53933 P15891 anti tag coimmunoprecipitation 11805837 physical association X 2 P53933 P15891 anti tag coimmunoprecipitation 11805837 physical association X 2 P53933 P15891 two hybrid 11743162 physical association X 2 P53933 P15891 phage display 11668184 physical association X 2 P15891 anti tag coimmunoprecipitation 11805837 - C 4 P15891 anti tag coimmunoprecipitation 11805837 - C 13 P15891 anti tag coimmunoprecipitation 11805837 - C 18 P15891 anti tag coimmunoprecipitation 11805837 - C 56 P15891 anti tag coimmunoprecipitation 11805837 - C 13 P15891 anti tag coimmunoprecipitation 11805837 - C 9 P12695 P15891 anti tag coimmunoprecipitation 11805837 physical association X 2 P53974 P15891 nuclear magnetic resonance 18701719 direct interaction X 2 P53974 P15891 two hybrid 11743162 direct interaction X 2 P53974 P15891 phage display 11668184 direct interaction X 2 P53974 P15891 coimmunoprecipitation 11668184 direct interaction X 2 P17555 P15891 genetic interference 9190214 physical association X 2 P17555 P15891 two hybrid 11743162 physical association X 2 P17555 P15891 experimental interaction detection 9190214 physical association X 2 P17555 P15891 two hybrid 11489916 physical association X 2 P17555 P15891 two hybrid 11668184 physical association X 2 P17555 P15891 two hybrid 11489916 physical association X 2 P17555 P15891 coimmunoprecipitation 11950888 physical association X 2 P17555 P15891 genetic interference 8552082 physical association X 2 P17555 P15891 filter binding 8552082 physical association X 2 Q12134 P15891 two hybrid 11743162 physical association X 2 Q12134 P15891 two hybrid pooling approach 11283351 physical association X 2 Q12134 P15891 two hybrid 10688190 physical association X 2 Q12134 P15891 two hybrid 11489916 physical association X 2 P15891 P00830 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P22137 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P07149 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P12709 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P0CS90 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P39004 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 Q08873 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P08458 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 P29295 anti tag coimmunoprecipitation 11805837 physical association X 2 P15891 Q04439 two hybrid 11668184 physical association X 2 P15891 P40563 two hybrid 11668184 physical association X 2 P15891 genetic interference 9008707 - X 2 P15891 tandem affinity purification 16429126 association C 3 P15891 anti tag coimmunoprecipitation 11805837 association C 7 P15891 anti tag coimmunoprecipitation 11805837 association C 3 P15891 pull down 23217712 association C 317 P15891 pull down 11950888 association C 3 P15891 filter binding 8552082 physical association C 6 P15891 filter binding 8552082 physical association C 6 P15891 filter binding 8552082 physical association C 6 P15891 anti tag coimmunoprecipitation 11805837 association C 61 Q12180 P15891 two hybrid pooling approach 19841731 physical association X 2 Q04093 P15891 inferred by author 19841731 direct interaction X 2 P40494 P15891 filamentous phage display 11668184 physical association X 2 P40494 P15891 two hybrid 11743162 physical association X 2 P40494 P15891 peptide array 14737190 direct interaction X 2 P40494 P15891 surface plasmon resonance 14737190 direct interaction X 2 P40494 P15891 pull down 14737190 physical association X 2 P40494 P15891 coimmunoprecipitation 14737190 physical association X 2 P40494 P15891 inferred by author 19841731 direct interaction X 2 P40494 P15891 two hybrid pooling approach 19841731 physical association X 2 P40494 P15891 peptide array 19841731 direct interaction X 2 P40494 P15891 peptide array 19841731 direct interaction X 2 P40494 P15891 peptide array 19841731 direct interaction X 2 P53145 P15891 peptide array 14737190 direct interaction X 2 P38274 P15891 two hybrid pooling approach 19841731 physical association X 2 P15891 P39743 two hybrid 10388809 physical association X 2 P15891 P39743 two hybrid 10388809 physical association X 2 P15891 P48562 two hybrid 10688190 physical association X 2 P15891 P50942 filamentous phage display 11668184 physical association X 2 P15891 P50942 two hybrid 11743162 physical association X 2 P15891 P32790 anti bait coimmunoprecipitation 11950888 physical association X 2 P15891 P32790 fluorescent resonance energy transfer 11950888 physical association X 2 P15891 P32790 fluorescence microscopy 11950888 colocalization X 2 P15891 P04819 peptide array 14737190 direct interaction X 2 P15891 P39743 peptide array 14737190 direct interaction X 2 P15891 P43603 peptide array 14737190 direct interaction X 2 P15891 P40960 peptide array 14737190 direct interaction X 2 P15891 P32793 peptide array 14737190 direct interaction X 2 P15891 P50942 anti tag coimmunoprecipitation 15798181 physical association X 2 P15891 P50942 anti tag coimmunoprecipitation 15798181 physical association X 2 P15891 P50942 fluorescence microscopy 15798181 colocalization X 2 P15891 P32790 inferred by author 19841731 direct interaction X 2 P15891 P50942 inferred by author 19841731 direct interaction X 2 P15891 Q06604 inferred by author 19841731 direct interaction X 2 P15891 Q06604 inferred by author 19841731 direct interaction X 2 P15891 P33200 two hybrid pooling approach 19841731 physical association X 2 P15891 P39743 inferred by author 19841731 direct interaction X 2 P15891 P39743 inferred by author 19841731 direct interaction X 2 P15891 P39743 inferred by author 19841731 direct interaction X 2 P15891 P53281 inferred by author 19841731 direct interaction X 2 P15891 P32793 inferred by author 19841731 direct interaction X 2 P15891 P32793 inferred by author 19841731 direct interaction X 2 P15891 Q06449 inferred by author 19841731 direct interaction X 2 P15891 P43603 peptide array 19841731 direct interaction X 2 P15891 P32793 peptide array 19841731 direct interaction X 2 P15891 Q02794 two hybrid pooling approach 19841731 physical association X 2 P15891 P43603 peptide array 19841731 direct interaction X 2 P15891 P43603 peptide array 19841731 direct interaction X 2 P15891 P43603 peptide array 19841731 direct interaction X 2 P15891 P25657 two hybrid pooling approach 19841731 physical association X 2 P15891 P53750 peptide array 19841731 direct interaction X 2 P15891 Q06604 peptide array 19841731 direct interaction X 2 P15891 Q06604 peptide array 19841731 direct interaction X 2 P15891 P32873 two hybrid pooling approach 19841731 physical association X 2 P15891 P43603 two hybrid pooling approach 19841731 physical association X 2 P15891 P32793 two hybrid pooling approach 19841731 physical association X 2 P15891 P39743 miniaturized immunoprecipitation 23267104 direct interaction X 2 P15891 P39743 miniaturized immunoprecipitation 23267104 direct interaction X 2 P15891 P39743 filter binding 9190214 physical association X 2 P53933 P15891 filamentous phage display 11668184 physical association X 2 P53933 P15891 two hybrid array 11743162 physical association X 2 P53933 P15891 two hybrid 11743162 physical association X 2 P53933 P15891 two hybrid 11743162 physical association X 2 P53933 P15891 surface plasmon resonance 14737190 direct interaction X 2 P53933 P15891 pull down 14737190 physical association X 2 P53933 P15891 coimmunoprecipitation 14737190 physical association X 2 P53933 P15891 two hybrid pooling approach 19841731 physical association X 2 P53933 P15891 miniaturized immunoprecipitation 23267104 direct interaction X 2 P15891 coimmunoprecipitation 15798181 physical association C 4 P15891 coimmunoprecipitation 15798181 physical association C 4 P15891 anti tag coimmunoprecipitation 11805837 association C 4 P15891 anti tag coimmunoprecipitation 20489023 association C 5 P15891 filamentous phage display 11668184 physical association C 6 P15891 filamentous phage display 11668184 physical association C 6 P15891 filamentous phage display 11668184 physical association C 6 P15891 anti tag coimmunoprecipitation 11805837 association C 9 P10592 P15891 tandem affinity purification 19536198 association X 2 P53974 P15891 filamentous phage display 11668184 physical association X 2 P53974 P15891 two hybrid 11743162 physical association X 2 P53974 P15891 fluorescence technology 14668868 physical association X 2 P53974 P15891 surface plasmon resonance 14737190 direct interaction X 2 P53974 P15891 peptide array 14737190 direct interaction X 2 P53974 P15891 isothermal titration calorimetry 17409071 physical association X 2 P53974 P15891 inferred by author 19841731 direct interaction X 2 P53974 P15891 inferred by author 19841731 direct interaction X 2 P53974 P15891 two hybrid pooling approach 19841731 physical association X 2 P53974 P15891 peptide array 19841731 direct interaction X 2 P53974 P15891 peptide array 19841731 direct interaction X 2 P04051 P15891 two hybrid pooling approach 19841731 physical association X 2 P17555 P15891 two hybrid 11668184 physical association X 2 P17555 P15891 two hybrid 11743162 physical association X 2 P17555 P15891 anti bait coimmunoprecipitation 11950888 physical association X 2 P17555 P15891 peptide array 14737190 direct interaction X 2 P17555 P15891 surface plasmon resonance 14737190 direct interaction X 2 P17555 P15891 isothermal titration calorimetry 17409071 physical association X 2 P17555 P15891 inferred by author 19841731 direct interaction X 2 P17555 P15891 miniaturized immunoprecipitation 23267104 direct interaction X 2 P17555 P15891 filter binding 9190214 physical association X 2 Q03796 P15891 peptide array 19841731 direct interaction X 2 Q12134 P15891 two hybrid 10688190 physical association X 2 Q12134 P15891 two hybrid fragment pooling approach 11283351 physical association X 2 Q12134 P15891 two hybrid array 11743162 physical association X 2 Q12134 P15891 two hybrid 18719252 physical association X 2 P15891 Q04439 two hybrid 11668184 physical association X 2 P15891 P40563 two hybrid 11668184 physical association X 2 P15891 Q08873 peptide array 14737190 direct interaction X 2 P15891 P40563 peptide array 14737190 direct interaction X 2 P15891 Q05580 peptide array 14737190 direct interaction X 2 P15891 P40563 surface plasmon resonance 14737190 direct interaction X 2 P15891 Q08873 surface plasmon resonance 14737190 direct interaction X 2 P15891 Q08873 pull down 14737190 physical association X 2 P15891 P40563 pull down 14737190 physical association X 2 P15891 Q08873 coimmunoprecipitation 14737190 physical association X 2 P15891 P40563 coimmunoprecipitation 14737190 physical association X 2 P15891 Q08873 isothermal titration calorimetry 17409071 physical association X 2 P15891 P38788 tandem affinity purification 19536198 association X 2 P15891 P35198 two hybrid pooling approach 19841731 physical association X 2 P15891 Q08873 inferred by author 19841731 direct interaction X 2 P15891 P22082 inferred by author 19841731 direct interaction X 2 P15891 Q02725 inferred by author 19841731 direct interaction X 2 P15891 Q04053 inferred by author 19841731 direct interaction X 2 P15891 Q04053 inferred by author 19841731 direct interaction X 2 P15891 P40563 inferred by author 19841731 direct interaction X 2 P15891 Q07830 inferred by author 19841731 direct interaction X 2 P15891 Q06639 two hybrid pooling approach 19841731 physical association X 2 P15891 P40563 peptide array 19841731 direct interaction X 2 P15891 P40563 peptide array 19841731 direct interaction X 2 P15891 P40563 peptide array 19841731 direct interaction X 2 P15891 P40563 peptide array 19841731 direct interaction X 2 P15891 P40563 peptide array 19841731 direct interaction X 2 P15891 P38266 peptide array 19841731 direct interaction X 2 P15891 Q08873 peptide array 19841731 direct interaction X 2 P15891 P22516 two hybrid pooling approach 19841731 physical association X 2 P15891 Q04439 fluorescence microscopy 20647997 physical association X 2 P47068 P15891 inferred by author 19841731 direct interaction X 2 P15891 mass spectrometry studies of complexes 11805837 - C 5 P15891 mass spectrometry studies of complexes 11805837 - C 57 P15891 mass spectrometry studies of complexes 11805837 - C 10 P15891 mass spectrometry studies of complexes 11805837 - C 3 P15891 confirmational text mining - - C 25 P15891 mass spectrometry studies of complexes 11805837 - C 8 P15891 mass spectrometry studies of complexes 11805837 - C 8 P40494 P15891 two hybrid 11743162 - X 2 P15891 P48562 two hybrid 11489916 - X 2 P15891 P39743 two hybrid 11489916 - X 2 P15891 P48562 two hybrid 11489916 - X 2 P15891 P39743 two hybrid 11489916 - X 2 P15891 P32599 interaction detection method 8334302 - X 2 P15891 P39743 two hybrid 7719850 - X 2 P15891 P39743 interaction detection method 9057315 - X 2 P15891 P39743 two hybrid 7719850,9057315 - X 2 P15891 P39743 two hybrid - - X 2 P15891 P60010 interaction detection method 8243992 - X 2 P15891 P60010 interaction detection method - - X 2 P15891 P60010 affinity chromatography technology 3060468 - X 2 P15891 P50942 two hybrid 11743162 - X 2 P15891 P33338 interaction detection method - - X 2 P15891 P33338 interaction detection method 8335689 - X 2 P15891 P32790 interaction detection method - - X 2 P15891 P32790 interaction detection method 8335689 - X 2 P53933 P15891 two hybrid 11489916 - X 2 P53933 P15891 two hybrid 11489916 - X 2 P53933 P15891 two hybrid 11743162 - X 2 P15891 mass spectrometry studies of complexes 11805837 - C 5 P53974 P15891 two hybrid 11743162 - X 2 P17555 P15891 two hybrid 11489916 - X 2 P17555 P15891 two hybrid 11489916 - X 2 P17555 P15891 interaction detection method - - X 2 P17555 P15891 two hybrid 11743162 - X 2 P17555 P15891 interaction detection method 8552082 - X 2 Q12134 P15891 two hybrid 11489916 - X 2 Q12134 P15891 two hybrid 11489916 - X 2 Q12134 P15891 two hybrid 11283351 - X 2 Q12134 P15891 two hybrid 11743162 - X 2

PPI - HINT Gene A Gene B PMID Method Quality RPO31 ABP1 19841731,19841731 0398,0018 HT CDC9 ABP1 14737190,14737190 0081,0045 HT MYO1 ABP1 26921299,26921299 0004,0090 LC ABP1 ABP1 11668184,15798181,8552082 0048,0019,0049 LC ABP1 SRV2 14680631,11743162,11489916,9190214,11950888,11950888,11743162,11668184,9190214,14737190,23267104,8552082,14737190,8552082,9190214,17409071,11950888,14737190 0401,0018,0018,0045,0019,0006,0397,0018,0049,0045,0946,0049,0107,0096,0096,0065,0004,0081 LC,HT ABP1 CHL1 19841731,19841731 0398,0018 HT ABP1 P25657 19841731,19841731 0398,0018 HT ABP1 MKK1 21118957 0090 HT ABP1 SLA1 11950888,11950888,11950888,11950888,11950888,11950888,11950888,18952899 0019,0416,0096,0006,0004,0055,0045,0055 LC ABP1 YSC84 19841731,19841731,19841731,14737190,19841731,14737190 0081,0018,0363,0081,0398,0045 HT ABP1 BEM3 19841731,19841731 0398,0018 HT ABP1 PDR3 19841731,19841731 0398,0018 HT ABP1 MTH1 19841731,19841731 0398,0018 HT ABP1 AIM3 19841731 0081 HT ABP1 HSL7 19841731,19841731 0398,0018 HT ABP1 RVS167 9190214,9190214,23267104,10388809,14737190,11489916,14737190,7719850,9190214,9190214,9057315 0018,0019,0946,0018,0081,0018,0045,0018,0045,0049,0018 LC,HT ABP1 PRK1 14737190,11743162,11668184,11743162,19841731,11668184,19841731,14737190,14737190,14737190,11668184,14737190,19841731,11668184,14737190,14737190,19841731 0096,0018,0019,0397,0363,0018,0398,0007,0045,0107,0048,0004,0018,0004,0081,0019,0081 HT,LC ABP1 AIM21 14737190,19841731,11668184,14737190,14737190,19841731,14737190,14737190,14737190,14737190 0096,0363,0018,0107,0081,0081,0019,0004,0007,0045 HT,LC ABP1 PAC11 14737190,14737190 0081,0045 HT ABP1 PXA1 23831759 0090 HT ABP1 LSB3 19841731,19841731,14737190,19841731,14737190 0081,0018,0081,0398,0045 HT ABP1 ARP3 11331312 0401 LC ABP1 CLA4 11489916,10688190 0018,0018 HT ABP1 INP52 15798181,11743162,11743162,15798181,15798181,15798181,11668184,11668184,15798181,15798181 0428,0397,0018,0019,0004,0007,0048,0084,0416,0021 LC,HT ABP1 PEX14 14668868 0045 LC ABP1 LSG1 14737190,14737190 0081,0045 HT ABP1 P53750 19841731 0081 HT ABP1 APP1 14737190,19841731,23267104,11743162,11668184,11743162,14737190,14737190,11489916,11668184,14737190,19841731,14737190 0096,0018,0946,0397,0084,0018,0107,0019,0018,0048,0004,0398,0007 HT,LC ABP1 ARK1 11668184,11743162,11668184,18701719,14668868,11743162,19841731,19590096,19841731,11668184,14737190,14737190,11668184,19841731,17409071,14737190,19841731 0084,0018,0019,0077,0051,0397,0363,0114,0398,0004,0045,0107,0048,0018,0065,0081,0081 LC,HT ABP1 ACT1 11331312 0401 LC ABP1 STD1 19841731,19841731 0398,0018 HT ABP1 TPP1 19841731 0081 HT ABP1 MYO5 11668184,20647997 0018,0416 LC ABP1 HEL2 14737190,14737190 0081,0045 HT ABP1 BSP1 19841731,19841731 0363,0081 HT ABP1 RSC3 19841731,19841731 0398,0018 HT ABP1 SCP1 14737190,17409071,19841731,14737190,14737190,19841731,14737190,14737190,14737190,14737190 0096,0065,0363,0107,0081,0081,0019,0004,0007,0045 HT,LC ABP1 HUA2 18719252,11283351,11283351,11743162,11283351,11743162,11489916,10688190 0018,0018,0399,0397,0398,0018,0018,0018 HT ABP1 HAL9 19841731,19841731 0398,0018 HT CDC28 ABP1 24374311 0004 LC ATP2 ABP1 11805837 0007 HT GAL1 ABP1 11805837 0007 HT FAS1 ABP1 11805837 0007 HT SPS1 ABP1 11805837,11805837 0004,0007 HT MYO1 ABP1 26921299,26921299 0004,0090 LC LPD1 ABP1 11805837 0007 HT UBI4 ABP1 22106047 0004 LC SSC1 ABP1 11805837 0007 HT SSA1 ABP1 23217712 0096 LC SSA2 ABP1 19536198 0676 HT SSB1 ABP1 16429126 0676 HT LAT1 ABP1 11805837 0007 HT PGI1 ABP1 11805837 0007 HT ABP1 TUP1 11805837,11805837 0004,0007 HT ABP1 SRV2 14680631,9190214,11950888,11950888,19841731,9190214,8552082,8552082,9190214,11950888 0401,0045,0019,0006,0363,0049,0049,0096,0096,0004 LC ABP1 SNF2 19841731 0363 LC ABP1 CHC1 15992543,11805837 0428,0007 LC,HT ABP1 RVS161 17200106 0004 HT ABP1 HRR25 11805837,11805837 0004,0007 HT ABP1 ARP2 11331312 0004 LC ABP1 NAB2 19840948 0004 LC ABP1 SAC6 15534003,17200106 0428,0004 LC,HT ABP1 SLA1 11950888,11950888,11950888,11950888,19841731,11950888,11950888,11950888 0019,0416,0096,0006,0363,0004,0055,0045 LC ABP1 YSC84 11805837,19841731,19841731,19841731,19841731,11805837 0004,0081,0018,0363,0398,0007 HT,LC ABP1 ECM29 21321079 0004 LC ABP1 SSZ1 19536198 0676 HT ABP1 AIM46 11805837,11805837 0004,0007 HT ABP1 RPN10 18757749 0004 HT ABP1 HXT7 11805837,11805837 0004,0007 HT ABP1 RVS167 19841731 0363 LC ABP1 PRK1 14737190,11668184,19841731,11668184,19841731,14737190,14737190,11805837,14737190,11668184,14737190,11805837,19841731,11668184,14737190,14737190,19841731 0096,0019,0363,0018,0398,0007,0045,0004,0107,0048,0004,0007,0018,0004,0081,0019,0081 LC,HT ABP1 AIM21 14737190,19841731,14737190,14737190,19841731,14737190,14737190,14737190,14737190 0096,0363,0107,0081,0081,0019,0004,0007,0045 LC ABP1 RPN11 20170199,18757749 0004,0004 LC,HT ABP1 BBC1 19841731 0363 LC ABP1 ARP3 11805837,11331312,11805837 0004,0401,0007 HT,LC ABP1 UBC9 23712011 0004 LC ABP1 INP52 15798181,19841731,15798181,15798181,15798181,15798181,15798181 0428,0363,0019,0004,0007,0416,0021 LC ABP1 LSB1 19841731 0363 LC ABP1 APP1 11805837,14737190,14737190,14737190,14737190,14737190,11805837 0004,0096,0107,0019,0004,0007,0007 HT,LC ABP1 ARK1 11668184,11668184,20489023,19841731,19841731,11668184,20489023,11668184,19841731,19841731 0084,0019,0007,0363,0398,0004,0004,0048,0018,0081 LC,HT ABP1 ACT1 3060468,11331312,16429126,17200106,11805837,3060468 0004,0401,0676,0004,0007,0428 LC,HT ABP1 VTC3 19841731 0363 LC ABP1 SNX41 19841731 0363 LC ABP1 Q04093 19841731 0363 LC ABP1 CRN1 17200106 0004 HT ABP1 PIN3 19841731 0363 LC ABP1 BSP1 19841731,19841731 0363,0081 LC ABP1 GPI13 19841731 0363 LC ABP1 SCP1 11805837,14737190,19841731,14737190,14737190,19841731,14737190,14737190,14737190,11805837,14737190 0004,0096,0363,0107,0081,0081,0019,0004,0007,0007,0045 HT,LC ABP1 LSP1 17200106 0004 HT ABP1 SMT3 15326169 0004 LC ABP1 LAS17 21035341 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P22516 P15891 CHL1 ABP1 0.286 19841731 Q04439 P15891 MYO5 ABP1 0.454 11668184,20647997 P60010 P15891 ACT1 ABP1 0.396 11331312,11805837,16429126,3060468 P53145 P15891 LSG1 ABP1 0.183 14737190 P16649 P15891 TUP1 ABP1 0.286 11805837 P15891 P11484 ABP1 SSB1 0.126 16429126 P15891 P04051 ABP1 RPO31 0.286 19841731 P15891 P04385 ABP1 GAL1 0.126 11805837 P15891 P12398 ABP1 SSC1 0.126 11805837 P15891 P12709 ABP1 PGI1 0.126 11805837 P25657 P15891 P25657 ABP1 0.354 19841731 P32599 P15891 SAC6 ABP1 0.126 15534003 P38788 P15891 SSZ1 ABP1 0.126 19536198 P53750 P15891 P53750 ABP1 0.332 19841731 P39004 P15891 HXT7 ABP1 0.286 11805837 P43603 P15891 LSB3 ABP1 0.523 14737190,19841731 P53281 P15891 LSB1 ABP1 0.332 19841731 Q04093 P15891 Q04093 ABP1 0.183 19841731 Q03796 P15891 TPP1 ABP1 0.183 19841731 Q12134 P15891 HUA2 ABP1 0.623 10688190,11489916,11743162,18719252,11283351 Q12446 P15891 LAS17 ABP1 0.126 21035341 P15891 P08458 ABP1 SPS1 0.332 11805837 P15891 P10080 ABP1 SBP1 0.126 23222640 P15891 P10591 ABP1 SSA1 0.126 23217712 P15891 P00830 ABP1 ATP2 0.126 11805837 P15891 P10592 ABP1 SSA2 0.126 19536198 P15891 P12695 ABP1 LAT1 0.126 11805837 P15891 P09624 ABP1 LPD1 0.126 11805837 P15891 P04819 ABP1 CDC9 0.183 14737190 P15891 P00546 ABP1 CDC28 0.126 24374311 P15891 P07149 ABP1 FAS1 0.126 11805837 P15891 P08964 ABP1 MYO1 0.286 26921299 P32873 P15891 BEM3 ABP1 0.286 19841731 P35198 P15891 MTH1 ABP1 0.286 19841731 P40563 P15891 AIM21 ABP1 0.837 11668184,19841731,14737190 P50942 P15891 INP52 ABP1 0.876 19590096,11668184,19841731,11743162,15798181 Q02794 P15891 STD1 ABP1 0.286 19841731 Q06604 P15891 BSP1 ABP1 0.554 19841731 Q08873 P15891 SCP1 ABP1 0.876 17409071,19590096,19841731,14737190,11805837 Q12180 P15891 HAL9 ABP1 0.286 19841731 P43588 P15891 RPN11 ABP1 0.236 20170199,18757749 P32793 P15891 YSC84 ABP1 0.765 11805837,19841731,14737190 P53933 P15891 APP1 ABP1 0.899 11668184,23267104,19841731,11489916,11743162,11805837,14737190 P15891 P15891 ABP1 ABP1 0.554 15798181,11668184,8552082 P39743 P15891 RVS167 ABP1 0.902 23267104,19841731,11489916,14737190,10388809,9190214 P17555 P15891 SRV2 ABP1 0.891 23267104,11743162,14680631,9190214,8552082,14737190,11950888,17409071,11668184,19841731,11489916 P40494 P15891 PRK1 ABP1 0.928 11668184,19841731,11743162,14737190,11805837 P53974 P15891 ARK1 ABP1 0.988 19590096,11743162,14668868,20489023,14737190,18006656,17409071,11668184,19841731,18701719 P38266 P15891 AIM3 ABP1 0.332 19841731 P38274 P15891 HSL7 ABP1 0.286 19841731 P32381 P15891 ARP2 ABP1 0.21 11331312 P32490 P15891 MKK1 ABP1 0.183 21118957 P38737 P15891 ECM29 ABP1 0.126 21321079 P32505 P15891 NAB2 ABP1 0.126 19840948 P38885 P15891 AIM46 ABP1 0.236 11805837 P38886 P15891 RPN10 ABP1 0.126 18757749 P32790 P15891 SLA1 ABP1 0.436 11950888,18952899,19841731 P33200 P15891 PDR3 ABP1 0.354 19841731 P29295 P15891 HRR25 ABP1 0.21 11805837 P40960 P15891 PAC11 ABP1 0.183 14737190 P47068 P15891 BBC1 ABP1 0.332 19841731 P47117 P15891 ARP3 ABP1 0.396 11805837,11331312 P48562 P15891 CLA4 ABP1 0.236 10688190,11489916 P50623 P15891 UBC9 ABP1 0.126 23712011 Q02725 P15891 VTC3 ABP1 0.332 19841731 Q06449 P15891 PIN3 ABP1 0.332 19841731 Q06639 P15891 RSC3 ABP1 0.354 19841731 Q07830 P15891 GPI13 ABP1 0.332 19841731 Q04053 P15891 SNX41 ABP1 0.332 19841731 Q05580 P15891 Q05580 ABP1 0.183 14737190 P22082 P15891 SNF2 ABP1 0.332 19841731 P22137 P15891 CHC1 ABP1 0.126 11805837