PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBC9 INN1 22623719 biogrid exp DRS1 UBC9 23712011 biogrid exp UBC9 HMO1 23712011 biogrid exp UBC9 LEU9 23712011 biogrid exp BEM4 UBC9 10688190 mint,intact,dip exp TSL1 UBC9 23712011 biogrid exp RNQ1 UBC9 23712011 biogrid exp ABP1 UBC9 23712011 biogrid exp MRM1 UBC9 23712011 biogrid exp KAR9 UBC9 18832349 biogrid exp SAP1 UBC9 23712011 biogrid exp LSM12 UBC9 23712011 biogrid exp UBC9 FPR4 23712011 biogrid exp ILV3 UBC9 23712011 biogrid exp TIF4632 UBC9 23712011 biogrid exp MRE11 UBC9 23122649 biogrid exp CST26 UBC9 23712011 biogrid exp SRP21 UBC9 23712011 biogrid exp SSA1 UBC9 19536198 intact exp UBC9 SLF1 22271760 biogrid exp UBC9 ARP9 23712011 biogrid exp UBC9 NOG1 23712011 biogrid exp NET1 UBC9 23712011 biogrid exp UBC9 Putative ATP-dependent RNA helicase YLR419W 23712011 biogrid exp UBC9 DBP10 23712011 biogrid exp TRR1 UBC9 23712011 biogrid exp NDE1 UBC9 23712011 biogrid exp RTS1 UBC9 23712011 biogrid exp UBC9 ERB1 23712011 biogrid exp RPA135 UBC9 23712011 biogrid exp UBC9 SLK19 17634282 biogrid exp MMS21 UBC9 22562154,19748359,15738391 biogrid exp YKT6 UBC9 23712011 biogrid exp UBC9 VPS72 23712011 biogrid exp UBC9 RDL1 23712011 biogrid exp AAP1 UBC9 23712011 biogrid exp UBC9 NOP12 23712011 biogrid exp CDC39 UBC9 23712011 biogrid exp UBC9 RRP5 23712011 biogrid exp SRP72 UBC9 23712011 biogrid exp UBC9 RLI1 23712011 biogrid exp SRP68 UBC9 23712011 biogrid exp RPG1 UBC9 23712011 biogrid exp UBC9 SXM1 23712011 biogrid exp NOP2 UBC9 23712011 biogrid exp UBC9 HEF3 23712011 biogrid exp UBC9 NOP13 23712011 biogrid exp QRI1 UBC9 23712011 biogrid exp NOP4 UBC9 23712011 biogrid exp RAD52 UBC9 23624404 biogrid exp UBC9 KAP114 22562154 biogrid exp UBC9 MRH1 23712011 biogrid exp DBP5 UBC9 23712011 biogrid exp BEM2 UBC9 23712011 biogrid exp ROK1 UBC9 23712011 biogrid exp UBC9 CDC14 23712011 biogrid exp UBC9 HOF1 23712011 biogrid exp SFP1 UBC9 23712011 biogrid exp CDC10 UBC9 23712011 biogrid exp UBC9 Uncharacterized protein YMR111C 23712011 biogrid exp UBC9 RPN9 23712011 biogrid exp RFC3 UBC9 23712011 biogrid exp UBC9 TMA64 23712011 biogrid exp UBC9 NOP7 23712011 biogrid exp UBC9 RRS1 23712011 biogrid exp UBC9 TAF12 23712011 biogrid exp UBC9 TSR1 23712011 biogrid exp NOC2 UBC9 23712011 biogrid exp TY1B-H UBC9 23712011 biogrid exp UBC9 ESC2 19158389 biogrid exp PRP6 UBC9 10688190 biogrid,i2d,mint,intact,dip exp NDI1 UBC9 23712011 biogrid exp UBC9 HAS1 23712011 biogrid exp SSE1 UBC9 19536198 intact exp ILV1 UBC9 23712011 biogrid exp RET2 UBC9 23712011 biogrid exp UTP10 UBC9 23712011 biogrid exp UBC9 SMD2 23712011 biogrid exp TYE7 UBC9 23712011 biogrid exp RPF2 UBC9 23712011 biogrid exp SEC18 UBC9 23712011 biogrid exp UBC9 ERG26 23712011 biogrid exp PAC1 UBC9 23034179 biogrid exp SSB2 UBC9 23332755,19536198 biogrid,intact exp TRX3 UBC9 23712011 biogrid exp RED1 UBC9 20534433 biogrid,dip exp SRO9 UBC9 22271760 biogrid exp SSB1 UBC9 19536198 intact exp NIP1 UBC9 23712011 biogrid exp UBC9 DCS1 23712011 biogrid exp SRS2 UBC9 22705796,15931174 biogrid,i2d exp KSP1 UBC9 23712011 biogrid exp BUD3 UBC9 23712011 biogrid exp UBC9 NSE5 14690591 biogrid,i2d,intact exp XRN1 UBC9 23712011 biogrid exp NDC80 UBC9 17634282 biogrid exp ATP4 UBC9 23712011 biogrid exp RPC37 UBC9 23712011 biogrid exp UBC9 TPS1 23712011 biogrid exp RAD5 UBC9 12226657 biogrid exp GCN2 UBC9 23712011 biogrid exp YPK1 UBC9 23712011 biogrid exp UBC9 NIP7 23712011 biogrid exp MIS1 UBC9 23712011 biogrid exp RPC40 UBC9 23712011 biogrid exp NUG1 UBC9 23712011 biogrid exp SWC3 UBC9 23712011 biogrid exp UBC9 TOF2 23712011 biogrid exp UBC9 DNM1 23712011 biogrid exp SPP41 UBC9 23712011 biogrid exp CDC12 UBC9 23712011 biogrid exp, ortho UBC9 KRE33 23712011 biogrid exp, ortho TOP2 UBC9 23712011 biogrid exp, ortho CDC3 UBC9 23712011,21518767 biogrid exp, ortho UBA1 UBC9 21209884, 23023127 biogrid exp, ortho, pred UBC9 AOS1 21209884,15738391, 23023127 biogrid exp, ortho, pred TAF5 UBC9 23712011, 23023127 biogrid exp, ortho, pred UBC9 UBC9 10688190,21518767,23644018, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred UBC9 UBA2 21209884,21518767,15738391,12354763,9341106, 23023127 biogrid exp, ortho, pred RAD51 UBC9 10688190, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred POL30 UBC9 23712011,18701921,12226657,23034805,18155241, 23023127 biogrid exp, ortho, pred UBC9 SIZ1 22705796,23443663,11577116,11572779,11587849,16109721,19748360,16204216,24753409,23571759, 23023127 biogrid,dip exp, pred CBF2 UBC9 17634282,16923829, 23023127 biogrid exp, pred BIM1 UBC9 18832349, 23023127 biogrid exp, pred UBC9 SMT3 11283351,23034805,18719252,17475278,23712011,10688190,18832349,12354763, 23023127 biogrid,i2d,mint,intact,dip exp, pred RAD18 UBC9 24224485,23034805,12226657, 23023127 biogrid exp, pred STH1 UBC9 23712011, 23023127 biogrid exp, pred SGS1 UBC9 17081974,19158389, 23023127 biogrid,intact exp, pred NAB2 UBC9 19840948, 23023127 biogrid exp, pred UBC9 NFI1 22705796,23395907,23443663,24753409,20516210,12761287,18499666,23571759, 23023127 biogrid exp, pred CEP3 UBC9 8668125, 23023127 biogrid,i2d,dip exp, pred STU2 UBC9 17634282, 23023127 biogrid exp, pred SPC42 UBC9 17634282, 23023127 biogrid exp, pred ARD1 UBC9 23712011, 23023127 biogrid exp, pred UBC9 CST9 16847351, 23023127 biogrid exp, pred SLX5 UBC9 17669696, 23023127 biogrid exp, pred UBC9 SPC24 17634282, 23023127 biogrid exp, pred NAM7 UBC9 18676617, 23023127 biogrid exp, pred CDC11 UBC9 23712011,11587849, 23023127 biogrid,dip exp, pred BIK1 UBC9 23034179, 23023127 biogrid exp, pred SLX8 UBC9 17669696, 23023127 biogrid exp, pred BIR1 UBC9 17634282, 23023127 biogrid exp, pred RAD6 UBC9 12226657, 23023127 biogrid exp, pred RPT5 UBC9 ortho CKB2 UBC9 ortho UBC9 LSC2 ortho SWD1 UBC9 ortho SNF7 UBC9 ortho SPT15 UBC9 ortho CHK1 UBC9 ortho CRM1 UBC9 ortho GLN1 UBC9 ortho UBC9 KAP95 ortho UBC9 LAP3 ortho UBC9 SEH1 ortho SNF1 UBC9 ortho UBC9 RRP45 ortho Deoxyribonuclease Tat-D UBC9 ortho BRR2 UBC9 ortho PRP8 UBC9 ortho UBC9 STE20 ortho ERG12 UBC9 ortho DBP2 UBC9 ortho RDH54 UBC9 ortho CHC1 UBC9 ortho UBC9 NOP58 ortho PCH2 UBC9 ortho UBC9 RIX7 ortho RPD3 UBC9 ortho UBC9 MEU1 ortho UBC9 MEX67 ortho UBC9 ESA1 ortho TOP1 UBC9 ortho NIC96 UBC9 ortho UBC9 TIF6 ortho UBC9 NOP56 ortho RNA1 UBC9 ortho RBG1 UBC9 ortho MBF1 UBC9 ortho UBC9 UTP22 ortho UBC9 RVB1 ortho RAD53 UBC9 ortho NAS2 UBC9 ortho HNT2 UBC9 ortho RPN10 UBC9 ortho SRM1 UBC9 23023127 ortho, pred UBC1 UBC9 23023127 ortho, pred IPL1 UBC9 23023127 ortho, pred UBC9 PEX10 23023127 ortho, pred UBC4 UBC9 23023127 ortho, pred CDC28 UBC9 23023127 ortho, pred FPR3 UBC9 23023127 pred PRE2 UBC9 23023127 pred UBC8 UBC9 23023127 pred UBC9 SKP1 23023127 pred UBC9 NPL3 23023127 pred CDC20 UBC9 23023127 pred PAB1 UBC9 23023127 pred CKA2 UBC9 23023127 pred PRE6 UBC9 23023127 pred UBC9 MLC1 23023127 pred SHP1 UBC9 23023127 pred CDC34 UBC9 23023127 pred CDC5 UBC9 23023127 pred UBC9 UBC11 23023127 pred PKC1 UBC9 23023127 pred CDC16 UBC9 23023127 pred PHO85 UBC9 23023127 pred UBC9 DOC1 23023127 pred UBC9 APC11 23023127 pred RSC8 UBC9 23023127 pred UBC9 APC5 23023127 pred UBC9 UBC12 23023127 pred HRR25 UBC9 23023127 pred UBC9 UBX5 23023127 pred UBC9 TUB4 23023127 pred TUB2 UBC9 23023127 pred UBC9 UBI4 23023127 pred UBC9 HUB1 23023127 pred DMA1 UBC9 23023127 pred RSP5 UBC9 23023127 pred UBC9 UBC7 23023127 pred UBC9 MDY2 23023127 pred UBC9 HRT1 23023127 pred FKH1 UBC9 23023127 pred PRE5 UBC9 23023127 pred BPL1 UBC9 23023127 pred DSK2 UBC9 23023127 pred UBC9 APC4 23023127 pred CDC23 UBC9 23023127 pred TUB1 UBC9 23023127 pred PEX4 UBC9 23023127 pred UBC9 ESP1 23023127 pred UBC9 APC2 23023127 pred UBC9 UBC13 23023127 pred SCP160 UBC9 23023127 pred UBC9 APC1 23023127 pred MPE1 UBC9 23023127 pred SCL1 UBC9 23023127 pred UBC9 SFH1 23023127 pred PRE8 UBC9 23023127 pred UBC9 UBX4 23023127 pred UBC9 CDH1 23023127 pred CDC27 UBC9 23023127 pred RAD23 UBC9 23023127 pred RSC6 UBC9 23023127 pred UBC9 MCD1 23023127 pred MCM3 UBC9 23023127 pred PRE4 UBC9 23023127 pred HSL1 UBC9 23023127 pred ATG12 UBC9 23023127 pred TIF5 UBC9 23023127 pred RFA1 UBC9 23023127 pred YDJ1 UBC9 23023127 pred MET30 UBC9 23023127 pred CDC25 UBC9 23023127 pred NAP1 UBC9 23023127 pred UBP6 UBC9 23023127 pred PUP2 UBC9 23023127 pred UBC9 CDC53 23023127 pred ATG8 UBC9 23023127 pred PAN1 UBC9 23023127 pred UBC9 RUB1 23023127 pred CDC24 UBC9 23023127 pred CSE4 UBC9 23023127 pred CKA1 UBC9 23023127 pred UBC6 UBC9 23023127 pred UBC5 UBC9 23023127 pred UBC9 MMS2 23023127 pred CKS1 UBC9 23023127 pred CDC26 UBC9 23023127 pred UBC9 LAS17 23023127 pred PUP1 UBC9 23023127 pred PRP19 UBC9 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P12954 P50623 - 15931174 - X 2 P25454 P50623 - 10688190 - X 2 P50623 P50623 - 10688190 - X 2 P50623 P19735 - 10688190 - X 2 P50623 Q12306 - 10688190 - X 2 P50623 Q12306 - 10655498 - X 2 P50623 Q03718 - 14690591 - X 2 P50623 Q12306 - 11283351 - X 2 P50623 Q12306 - 9341106 - X 2 P25342 P50623 affinity chromatography technology 23712011 physical association X 2 P22515 P50623 enzymatic study 21209884 direct interaction X 2 P10862 P50623 two hybrid 23034805 direct interaction X 2 P10862 P50623 two hybrid 23034805 direct interaction X 2 P10862 P50623 enzymatic study 23034805 direct interaction X 2 P10862 P50623 affinity chromatography technology 12226657 physical association X 2 P10862 P50623 two hybrid 24224485 direct interaction X 2 P10862 P50623 pull down 23034805 direct interaction X 2 Q06151 P50623 affinity chromatography technology 23712011 physical association X 2 P43621 P50623 affinity chromatography technology 23712011 physical association X 2 P38691 P50623 affinity chromatography technology 23712011 physical association X 2 Q05022 P50623 affinity chromatography technology 23712011 physical association X 2 P07703 P50623 affinity chromatography technology 23712011 physical association X 2 P52488 P50623 pull down 15738391 direct interaction X 2 P52488 P50623 pull down 21518767 direct interaction X 2 P52488 P50623 enzymatic study 12354763 direct interaction X 2 P52488 P50623 pull down 12354763 direct interaction X 2 P52488 P50623 enzymatic study 9341106 direct interaction X 2 P52488 P50623 x-ray crystallography 21209884 association X 2 P52488 P50623 enzymatic study 21209884 direct interaction X 2 P39936 P50623 affinity chromatography technology 23712011 physical association X 2 Q03195 P50623 affinity chromatography technology 23712011 physical association X 2 P53883 P50623 affinity chromatography technology 23712011 physical association X 2 P38904 P50623 affinity chromatography technology 23712011 physical association X 2 P06778 P50623 enzymatic study 23624404 direct interaction X 2 Q04477 P50623 two hybrid 17634282 direct interaction X 2 P32526 P50623 two hybrid 18832349 direct interaction X 2 P32526 P50623 pull down 18832349 direct interaction X 2 P32526 P50623 pull down 18832349 direct interaction X 2 P36015 P50623 affinity chromatography technology 23712011 physical association X 2 P40991 P50623 affinity chromatography technology 23712011 physical association X 2 P25372 P50623 affinity chromatography technology 23712011 physical association X 2 P38828 P50623 affinity chromatography technology 23712011 physical association X 2 P38629 P50623 affinity chromatography technology 23712011 physical association X 2 P20449 P50623 affinity chromatography technology 23712011 physical association X 2 Q03973 P50623 affinity chromatography technology 23712011 physical association X 2 P38129 P50623 affinity chromatography technology 23712011 physical association X 2 P12954 P50623 enzymatic study 22705796 direct interaction X 2 P12954 P50623 pull down 22705796 direct interaction X 2 P12954 P50623 two hybrid 22705796 direct interaction X 2 P12954 P50623 two hybrid 15931174 direct interaction X 2 P25655 P50623 affinity chromatography technology 23712011 physical association X 2 P06786 P50623 affinity chromatography technology 23712011 physical association X 2 P32342 P50623 affinity chromatography technology 23712011 physical association X 2 P53067 P50623 enzymatic study 22562154 direct interaction X 2 Q07381 P50623 affinity chromatography technology 23712011 physical association X 2 Q08581 P50623 two hybrid 17634282 direct interaction X 2 Q03388 P50623 affinity chromatography technology 23712011 physical association X 2 P36160 P50623 affinity chromatography technology 23712011 physical association X 2 Q05123 P50623 affinity chromatography technology 23712011 physical association X 2 Q03761 P50623 affinity chromatography technology 23712011 physical association X 2 P05626 P50623 affinity chromatography technology 23712011 physical association X 2 P42945 P50623 affinity chromatography technology 23712011 physical association X 2 P15891 P50623 affinity chromatography technology 23712011 physical association X 2 P25367 P50623 affinity chromatography technology 23712011 physical association X 2 Q12117 P50623 affinity chromatography technology 23712011 physical association X 2 P32432 P50623 affinity chromatography technology 23712011 physical association X 2 Q06698 P50623 affinity chromatography technology 23712011 physical association X 2 Q08746 P50623 affinity chromatography technology 23712011 physical association X 2 P12688 P50623 affinity chromatography technology 23712011 physical association X 2 Q12216 P50623 pull down 12761287 direct interaction X 2 Q12216 P50623 two hybrid 12761287 direct interaction X 2 P32892 P50623 affinity chromatography technology 23712011 physical association X 2 Q12216 P50623 pull down 20516210 direct interaction X 2 Q12216 P50623 pull down 23571759 direct interaction X 2 Q12216 P50623 enzymatic study 18499666 direct interaction X 2 Q12216 P50623 pull down 23395907 direct interaction X 2 Q12216 P50623 pull down 24753409 direct interaction X 2 Q12216 P50623 pull down 23443663 direct interaction X 2 Q12216 P50623 pull down 22705796 direct interaction X 2 P36094 P50623 two hybrid 17634282 direct interaction X 2 Q04062 P50623 affinity chromatography technology 23712011 physical association X 2 P63279 P50623 two hybrid 8668125 direct interaction X 2 P39960 P50623 affinity chromatography technology 23712011 physical association X 2 P46675 P50623 two hybrid 17634282 direct interaction X 2 P40215 P50623 affinity chromatography technology 23712011 physical association X 2 P54861 P50623 affinity chromatography technology 23712011 physical association X 2 P25454 P50623 two hybrid 10688190 direct interaction X 2 P50623 P53901 protein complementation assay 22623719 direct interaction X 2 P50623 P00927 affinity chromatography technology 23712011 physical association X 2 P50623 P39522 affinity chromatography technology 23712011 physical association X 2 P50623 P53914 affinity chromatography technology 23712011 physical association X 2 P50623 P47035 affinity chromatography technology 23712011 physical association X 2 P50623 P38688 affinity chromatography technology 23712011 physical association X 2 P50623 P32597 affinity chromatography technology 23712011 physical association X 2 P50623 Q00764 affinity chromatography technology 23712011 physical association X 2 P50623 P32829 two hybrid 23122649 direct interaction X 2 P50623 P50623 enzymatic study 21518767 direct interaction X 2 P50623 P47035 pull down 23712011 direct interaction X 2 P50623 P50623 two hybrid 10688190 direct interaction X 2 P09440 P50623 affinity chromatography technology 23712011 physical association X 2 Q00684 P50623 pull down 23712011 direct interaction X 2 P14291 P50623 two hybrid 20534433 direct interaction X 2 P33122 P50623 affinity chromatography technology 23712011 physical association X 2 Q12389 P50623 affinity chromatography technology 23712011 physical association X 2 P15442 P50623 affinity chromatography technology 23712011 physical association X 2 Q12305 P50623 affinity chromatography technology 23712011 physical association X 2 P40013 P50623 two hybrid 18832349 direct interaction X 2 P40072 P50623 two hybrid 17669696 direct interaction X 2 P38427 P50623 affinity chromatography technology 23712011 physical association X 2 P07347 P50623 affinity chromatography technology 23712011 physical association X 2 P22147 P50623 affinity chromatography technology 23712011 physical association X 2 P25558 P50623 affinity chromatography technology 23712011 physical association X 2 P32504 P50623 two hybrid 16923829 direct interaction X 2 P32504 P50623 two hybrid 17634282 direct interaction X 2 P53199 P50623 affinity chromatography technology 23712011 physical association X 2 P06104 P50623 two hybrid 12226657 direct interaction X 2 P0CG63 P50623 affinity chromatography technology 24596250 physical association X 2 P35187 P50623 two hybrid 19158389 direct interaction X 2 P43123 P50623 affinity chromatography technology 23712011 physical association X 2 P29509 P50623 affinity chromatography technology 23712011 physical association X 2 P18759 P50623 affinity chromatography technology 23712011 physical association X 2 P32497 P50623 affinity chromatography technology 23712011 physical association X 2 P40460 P50623 two hybrid 17634282 direct interaction X 2 Q06340 P50623 two hybrid 19158389 direct interaction X 2 Q06032 P50623 pull down 16847351 direct interaction X 2 Q06032 P50623 two hybrid 16847351 direct interaction X 2 P53978 P50623 affinity chromatography technology 23712011 physical association X 2 Q02208 P50623 affinity chromatography technology 23712011 physical association X 2 Q02208 P50623 pull down 23712011 direct interaction X 2 P31376 P50623 affinity chromatography technology 23712011 physical association X 2 Q04461 P50623 affinity chromatography technology 23712011 physical association X 2 P38226 P50623 affinity chromatography technology 23712011 physical association X 2 P15873 P50623 two hybrid 23034805 direct interaction X 2 P15873 P50623 affinity chromatography technology 23712011 physical association X 2 P15873 P50623 two hybrid 12226657 direct interaction X 2 P15873 P50623 enzymatic study 18155241 direct interaction X 2 P15873 P50623 enzymatic study 18701921 direct interaction X 2 P38687 P50623 affinity chromatography technology 23712011 physical association X 2 P37838 P50623 affinity chromatography technology 23712011 physical association X 2 P30771 P50623 pull down 18676617 direct interaction X 2 P53261 P50623 affinity chromatography technology 23712011 physical association X 2 P32458 P50623 affinity chromatography technology 11587849 physical association X 2 P32458 P50623 affinity chromatography technology 23712011 physical association X 2 Q06624 P50623 pull down 15738391 direct interaction X 2 Q06624 P50623 enzymatic study 21209884 direct interaction X 2 P22138 P50623 affinity chromatography technology 23712011 physical association X 2 O13535 P50623 affinity chromatography technology 23712011 physical association X 2 P32340 P50623 affinity chromatography technology 23712011 physical association X 2 Q04600 P50623 affinity chromatography technology 23712011 physical association X 2 P40969 P50623 two hybrid 8668125 direct interaction X 2 P40150 P50623 biochemical 23332755 association X 2 P47134 P50623 two hybrid 17634282 direct interaction X 2 P45818 P50623 affinity chromatography technology 23712011 physical association X 2 P32849 P50623 affinity chromatography technology 12226657 physical association X 2 P32849 P50623 two hybrid 12226657 direct interaction X 2 P32468 P50623 affinity chromatography technology 23712011 physical association X 2 P37898 P50623 affinity chromatography technology 23712011 physical association X 2 Q03532 P50623 affinity chromatography technology 23712011 physical association X 2 P11709 P50623 two hybrid 23034179 direct interaction X 2 P11709 P50623 enzymatic study 23034179 direct interaction X 2 P25270 P50623 affinity chromatography technology 23712011 physical association X 2 P32828 P50623 two hybrid 17669696 direct interaction X 2 P32457 P50623 affinity chromatography technology 23712011 physical association X 2 P32457 P50623 enzymatic study 21518767 direct interaction X 2 Q08962 P50623 affinity chromatography technology 23712011 physical association X 2 P39744 P50623 affinity chromatography technology 23712011 physical association X 2 P38249 P50623 affinity chromatography technology 23712011 physical association X 2 P39955 P50623 affinity chromatography technology 23712011 physical association X 2 P40984 P50623 two hybrid 8668125 direct interaction X 2 Q02892 P50623 affinity chromatography technology 23712011 physical association X 2 P50623 Q12306 two hybrid 23034805 direct interaction X 2 P50623 Q12306 two hybrid 23034805 direct interaction X 2 P50623 Q04195 affinity chromatography technology 11587849 physical association X 2 P50623 P39946 two hybrid 23034179 direct interaction X 2 P50623 Q04195 pull down 11572779 direct interaction X 2 P50623 Q04195 pull down 11577116 direct interaction X 2 P50623 Q04195 two hybrid 11577116 direct interaction X 2 P50623 Q12306 pull down 12354763 direct interaction X 2 P50623 Q12306 protein complementation assay 23403034 direct interaction X 2 P50623 Q12306 enzymatic study 23644018 direct interaction X 2 P50623 Q04660 affinity chromatography technology 23712011 physical association X 2 P50623 Q06205 affinity chromatography technology 23712011 physical association X 2 P50623 Q05080 affinity chromatography technology 23712011 physical association X 2 P50623 Q12166 affinity chromatography technology 23712011 physical association X 2 P50623 Q08208 affinity chromatography technology 23712011 physical association X 2 P50623 P40010 affinity chromatography technology 23712011 physical association X 2 P50623 P36121 affinity chromatography technology 23712011 physical association X 2 P50623 P38903 affinity chromatography technology 23712011 physical association X 2 P50623 Q06217 affinity chromatography technology 23712011 physical association X 2 P50623 Q12306 affinity chromatography technology 23712011 physical association X 2 P50623 Q04175 affinity chromatography technology 23712011 physical association X 2 P50623 Q12306 affinity chromatography technology 23935535 physical association X 2 P50623 Q12306 pull down 24224485 direct interaction X 2 P50623 P38632 pull down 19748359 direct interaction X 2 P50623 P38632 pull down 15738391 direct interaction X 2 P50623 P38632 pull down 22562154 direct interaction X 2 P50623 Q04195 pull down 23571759 direct interaction X 2 P50623 Q04195 pull down 16204216 direct interaction X 2 P50623 Q12306 affinity chromatography technology 21518767 physical association X 2 P50623 Q12306 affinity chromatography technology 21518767 physical association X 2 P50623 Q04195 pull down 24753409 direct interaction X 2 P50623 Q04195 pull down 23443663 direct interaction X 2 P50623 Q12306 enzymatic study 18832349 direct interaction X 2 P50623 Q04195 pull down 22705796 direct interaction X 2 P50623 Q12306 pull down 23712011 direct interaction X 2 P50623 Q04195 affinity chromatography technology 16109721 physical association X 2 P50623 Q04195 pull down 16109721 direct interaction X 2 P50623 Q12306 x-ray crystallography 17475278 association X 2 P50623 Q12306 two hybrid 18719252 direct interaction X 2 P50623 Q04195 enzymatic study 19748360 direct interaction X 2 P50623 Q12306 affinity chromatography technology 15326169 physical association X 2 P50623 Q12306 affinity chromatography technology 15166219 physical association X 2 P50623 Q03718 two hybrid 14690591 direct interaction X 2 P50623 Q12306 affinity chromatography technology 15542864 physical association X 2 P50623 P19735 two hybrid 10688190 direct interaction X 2 P50623 Q12306 two hybrid 10688190 direct interaction X 2 P25454 P50623 two hybrid 10688190 physical association X 2 P14291 P50623 two hybrid 20534433 physical association X 2 P39011 P50623 two hybrid 10688190 physical association X 2 P32458 P50623 coimmunoprecipitation 11587849 physical association X 2 P40969 P50623 two hybrid 8668125 physical association X 2 P50623 P19735 two hybrid 10688190 physical association X 2 P50623 Q12306 two hybrid pooling approach 11283351 physical association X 2 P50623 Q12306 two hybrid 10655498 physical association X 2 P50623 Q12306 two hybrid 10688190 physical association X 2 P50623 Q04195 coimmunoprecipitation 11587849 physical association X 2 P50623 P50623 two hybrid 10688190 physical association Y 1 P32589 P50623 tandem affinity purification 19536198 association X 2 P11484 P50623 tandem affinity purification 19536198 association X 2 P25454 P50623 two hybrid 10688190 physical association X 2 P50623 P50623 two hybrid 10688190 physical association X 2 P50623 P50623 two hybrid 10688190 physical association X 2 P35187 P50623 two hybrid 17081974 physical association X 2 P39011 P50623 two hybrid 10688190 physical association X 2 P40150 P50623 tandem affinity purification 19536198 association X 2 P10591 P50623 tandem affinity purification 19536198 association X 2 P50623 P19735 two hybrid 10688190 physical association X 2 P50623 Q12306 two hybrid 10688190 physical association X 2 P50623 Q12306 two hybrid fragment pooling approach 11283351 physical association X 2 P50623 Q03718 two hybrid array 14690591 physical association X 2 P50623 Q12306 two hybrid 18719252 physical association X 2 P25454 P50623 two hybrid 10688190 - X 2 P50623 P50623 two hybrid 10688190 - X 2 P40969 P50623 two hybrid - - X 2 P50623 P19735 two hybrid 10688190 - X 2 P50623 Q12306 two hybrid 10655498 - X 2 P50623 Q12306 two hybrid 10688190 - X 2 P50623 Q12306 two hybrid 11283351 - X 2 P50623 Q12306 affinity chromatography technology 9341106 - X 2

PPI - HINT Gene A Gene B PMID Method Quality RAD6 UBC9 12226657 0018 LC RAD52 UBC9 23624404 0415 LC RAD18 UBC9 23034805,12226657,24224485,12226657,24224485,23034805,23034805 0018,0018,0096,0004,0018,0096,0415 LC BIK1 UBC9 23034179,23034179 0415,0018 LC SRS2 UBC9 22705796,22705796,15931174,22705796 0018,0415,0018,0096 LC RED1 UBC9 20534433 0018 LC POL30 UBC9 23034805,18155241,18701921,12226657 0018,0415,0415,0018 LC PRP6 UBC9 10688190,10688190 0397,0018 HT UBA1 UBC9 21209884 0415 LC RAD51 UBC9 10688190,10688190 0397,0018 HT CDC3 UBC9 21518767 0415 LC CDC11 UBC9 11587849,11587849 0019,0004 LC CBF2 UBC9 17634282,16923829 0018,0018 HT,LC KAR9 UBC9 18832349,18832349 0096,0018 LC SLX5 UBC9 17669696 0018 LC MRE11 UBC9 23122649 0018 LC RAD5 UBC9 12226657,12226657 0004,0018 LC SGS1 UBC9 17081974,19158389 0018,0018 LC SPC42 UBC9 17634282 0018 HT BEM4 UBC9 10688190 0018 HT PAC1 UBC9 23034179 0018 LC BIM1 UBC9 18832349 0018 LC SLX8 UBC9 17669696 0018 LC SSB2 UBC9 23332755 0401 LC NDC80 UBC9 17634282 0018 HT CEP3 UBC9 8668125 0018 LC STU2 UBC9 17634282 0018 HT BIR1 UBC9 17634282 0018 HT UBC9 UBC9 16782883,21518767,23644018,17475278,10688190,10688190 0114,0415,0415,0114,0397,0018 LC,HT UBC9 UBA2 12354763,9341106,12354763,21209884,21209884 0415,0415,0096,0415,0114 LC UBC9 KAP114 22562154 0415 LC UBC9 INN1 22623719 0090 LC UBC9 NSE5 14690591,14690591 0018,0397 LC UBC9 SIZ1 19748360,11587849,11587849,11577116,11577116 0415,0004,0019,0096,0018 LC UBC9 SPC24 17634282 0018 HT UBC9 CST9 16847351,16847351 0018,0096 LC UBC9 ESC2 19158389 0018 LC UBC9 AOS1 21209884 0415 LC UBC9 SLK19 17634282 0018 HT UBC9 NFI1 12761287,18499666,12761287 0096,0415,0018 LC UBC9 SMT3 18832349,23034805,11283351,20543865,10688190,10688190,11283351,10655498,18719252,11283351,17475278 0415,0018,0398,0018,0397,0018,0399,0018,0018,0018,0114 LC,HT TY1B-H UBC9 23712011 0004 LC ILV1 UBC9 23712011 0004 LC ATP4 UBC9 23712011 0004 LC TOP2 UBC9 23712011 0004 LC ARD1 UBC9 23712011 0004 LC RPC40 UBC9 23712011 0004 LC MIS1 UBC9 23712011 0004 LC SSA1 UBC9 19536198 0676 HT RAD18 UBC9 23034805,12226657,24224485,12226657,24224485,23034805,23034805 0018,0018,0096,0004,0018,0096,0415 LC SSB1 UBC9 19536198 0676 HT YPK1 UBC9 23712011 0004 LC SRS2 UBC9 22705796,22705796,22705796 0018,0415,0096 LC GCN2 UBC9 23712011 0004 LC POL30 UBC9 23712011 0004 LC ABP1 UBC9 23712011 0004 LC SEC18 UBC9 23712011 0004 LC DBP5 UBC9 23712011 0004 LC RPA135 UBC9 23712011 0004 LC XRN1 UBC9 23712011 0004 LC MRM1 UBC9 23712011 0004 LC CDC10 UBC9 23712011 0004 LC RNQ1 UBC9 23712011 0004 LC TRX3 UBC9 23712011 0004 LC BUD3 UBC9 23712011 0004 LC CDC39 UBC9 23712011 0004 LC TRR1 UBC9 23712011 0004 LC NAM7 UBC9 18676617 0096 LC SWC3 UBC9 23712011 0004 LC NDI1 UBC9 23712011 0004 LC SRP21 UBC9 23712011 0004 LC SFP1 UBC9 23712011 0004 LC CDC3 UBC9 23712011 0004 LC CDC11 UBC9 11587849,23712011,11587849 0019,0004,0004 LC CDC12 UBC9 23712011 0004 LC NIP1 UBC9 23712011 0004 LC NAB2 UBC9 19840948 0004 LC KAR9 UBC9 18832349,18832349 0096,0018 LC SSE1 UBC9 19536198 0676 HT STH1 UBC9 23712011 0004 LC RAD5 UBC9 12226657,12226657 0004,0018 LC DRS1 UBC9 23712011 0004 LC TYE7 UBC9 23712011 0004 LC YKT6 UBC9 23712011 0004 LC RPC37 UBC9 23712011 0004 LC RPF2 UBC9 23712011 0004 LC NOP4 UBC9 23712011 0004 LC AAP1 UBC9 23712011 0004 LC TAF5 UBC9 23712011 0004 LC CST26 UBC9 23712011 0004 LC RPG1 UBC9 23712011 0004 LC TSL1 UBC9 23712011 0004 LC RFC3 UBC9 23712011 0004 LC MMS21 UBC9 19748359,22562154,15738391 0096,0096,0096 LC SRP68 UBC9 23712011 0004 LC SRP72 UBC9 23712011 0004 LC KSP1 UBC9 23712011 0004 LC LSM12 UBC9 23712011 0004 LC RTS1 UBC9 23712011 0004 LC SPP41 UBC9 23712011 0004 LC ILV3 UBC9 23712011 0004 LC NOC2 UBC9 23712011 0004 LC TIF4632 UBC9 23712011 0004 LC SAP1 UBC9 23712011 0004 LC BEM2 UBC9 23712011 0004 LC NUG1 UBC9 23712011 0004 LC SSB2 UBC9 19536198,23332755 0676,0401 HT,LC NDE1 UBC9 23712011 0004 LC NOP2 UBC9 23712011 0004 LC UTP10 UBC9 23712011 0004 LC QRI1 UBC9 23712011 0004 LC RET2 UBC9 23712011 0004 LC ROK1 UBC9 23712011 0004 LC NET1 UBC9 23712011,23712011 0096,0004 LC UBC9 UBA2 12354763,21518767,12354763,15738391 0415,0096,0096,0096 LC UBC9 ERG26 23712011 0004 LC UBC9 NOP7 23712011 0004 LC UBC9 NOP13 23712011 0004 LC UBC9 NAT10 23712011 0004 LC UBC9 HEF3 23712011 0004 LC UBC9 DNM1 23712011 0004 LC UBC9 CDC14 23712011 0096 LC UBC9 TPS1 23712011 0004 LC UBC9 TOF2 23712011,23712011 0096,0004 LC UBC9 NOG1 23712011 0004 LC UBC9 RLI1 23712011 0004 LC UBC9 VPS72 23712011 0004 LC UBC9 HAS1 23712011 0004 LC UBC9 TAF12 23712011 0004 LC UBC9 HMO1 23712011 0004 LC UBC9 RPN9 23712011 0004 LC UBC9 SXM1 23712011 0004 LC UBC9 SIZ1 23443663,16109721,11587849,22705796,11587849,11572779,23571759,11577116,24753409,16109721,16204216,11577116 0096,0004,0004,0096,0019,0096,0096,0096,0096,0096,0096,0018 LC UBC9 Q04461 23712011 0004 LC UBC9 TMA64 23712011 0004 LC UBC9 ERB1 23712011 0004 LC UBC9 RRP5 23712011 0004 LC UBC9 HOF1 23712011 0004 LC UBC9 ARP9 23712011 0004 LC UBC9 CST9 16847351,16847351 0018,0096 LC UBC9 DCS1 23712011 0004 LC UBC9 FPR4 23712011 0004 LC UBC9 SMD2 23712011 0004 LC UBC9 AOS1 15738391 0096 LC UBC9 Q06698 23712011 0004 LC UBC9 TSR1 23712011 0004 LC UBC9 NOP12 23712011 0004 LC UBC9 RRS1 23712011 0004 LC UBC9 NIP7 23712011 0004 LC UBC9 MRH1 23712011 0004 LC UBC9 LEU9 23712011 0004 LC UBC9 NFI1 23443663,22705796,23395907,23571759,12761287,20516210,12761287,24753409 0096,0096,0096,0096,0096,0096,0018,0096 LC UBC9 RDL1 23712011 0004 LC UBC9 SMT3 15542864,9341106,23712011,9435231,21518767,15326169,15166219,12354763,21209884,23712011 0004,0004,0004,0096,0096,0004,0004,0096,0096,0096 LC UBC9 DBP10 23712011 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q04477 P50623 SPC24 UBC9 0.183 17634282 P50623 P15873 UBC9 POL30 0.801 23712011,18701921,23034805,12226657,18155241 Q12034 P50623 SLF1 UBC9 0.126 22271760 Q12221 P50623 PUF2 UBC9 0.126 26668354 P50623 P25567 UBC9 SRO9 0.126 22271760 P50623 P12954 UBC9 SRS2 0.671 22705796 P50623 P14291 UBC9 RED1 0.309 20534433 P50623 P06104 UBC9 RAD6 0.309 12226657 P50623 P10862 UBC9 RAD18 0.843 24224485,23034805 Q06032 P50623 CST9 UBC9 0.523 16847351 P50623 P35187 UBC9 SGS1 0.523 17081974,19158389 P50623 P32849 UBC9 RAD5 0.454 12226657 Q02208 P50623 TOF2 UBC9 0.286 23712011 P50623 P32457 UBC9 CDC3 0.396 23712011,21518767 P50623 P47035 UBC9 NET1 0.286 23712011 P50623 P38632 UBC9 MMS21 0.671 22562154,19748359,15738391 Q12306 P50623 SMT3 UBC9 0.956 10688190,12354763,17475278,18832349,23034805,11283351,10655498,18719252,23712011 P52488 P50623 UBA2 UBC9 0.925 21209884,12354763,15738391,21518767,9341106 P50623 P36094 UBC9 SPC42 0.183 17634282 P50623 P32504 UBC9 CBF2 0.183 17634282 P50623 P32505 UBC9 NAB2 0.126 19840948 P50623 P32589 UBC9 SSE1 0.126 19536198 P50623 P32828 UBC9 SLX5 0.309 17669696 P50623 P32829 UBC9 MRE11 0.309 23122649 P50623 P39946 UBC9 PAC1 0.309 23034179 P50623 P40013 UBC9 BIM1 0.309 18832349 P50623 P40072 UBC9 SLX8 0.309 17669696 P50623 P40150 UBC9 SSB2 0.236 23332755,19536198 P50623 P40460 UBC9 TID3 0.183 17634282 P50623 P46675 UBC9 STU2 0.183 17634282 P50623 P40969 UBC9 CEP3 0.033 8668125 P50623 P47134 UBC9 BIR1 0.183 17634282 P50623 O13535 UBC9 TY1B-H 0.126 23712011 P50623 P00927 UBC9 ILV1 0.126 23712011 P50623 P05626 UBC9 ATP4 0.126 23712011 P50623 P06778 UBC9 RAD52 0.309 23624404 P50623 P06786 UBC9 TOP2 0.126 23712011 P50623 P07347 UBC9 ARD1 0.126 23712011 P50623 P07703 UBC9 RPC40 0.126 23712011 P50623 P09440 UBC9 MIS1 0.126 23712011 P50623 P10591 UBC9 SSA1 0.126 19536198 P50623 P11484 UBC9 SSB1 0.126 19536198 P50623 P11709 UBC9 BIK1 0.523 23034179 P50623 P12688 UBC9 YPK1 0.126 23712011 P50623 P15442 UBC9 GCN2 0.126 23712011 P50623 P15891 UBC9 ABP1 0.126 23712011 P50623 P18759 UBC9 SEC18 0.126 23712011 P50623 P19735 UBC9 PRP6 0.332 10688190 P50623 P20449 UBC9 DBP5 0.126 23712011 P50623 P20942 UBC9 PDC 0.309 16421094 P50623 P22138 UBC9 RPA135 0.126 23712011 P50623 P22147 UBC9 XRN1 0.126 23712011 P50623 P22515 UBC9 UBA1 0.309 21209884 P50623 P25270 UBC9 MRM1 0.126 23712011 P50623 P25342 UBC9 CDC10 0.126 23712011 P50623 P25367 UBC9 RNQ1 0.126 23712011 P50623 P25372 UBC9 TRX3 0.126 23712011 P50623 P25454 UBC9 RAD51 0.332 10688190 P50623 P25558 UBC9 BUD3 0.126 23712011 P50623 P25655 UBC9 CDC39 0.126 23712011 P50623 P29509 UBC9 TRR1 0.126 23712011 P50623 P30771 UBC9 NAM7 0.309 18676617 P50623 P31376 UBC9 SWC3 0.126 23712011 P50623 P32340 UBC9 NDI1 0.126 23712011 P50623 P32342 UBC9 SRP21 0.126 23712011 P50623 P32432 UBC9 SFP1 0.126 23712011 P50623 P32458 UBC9 CDC11 0.126 23712011,11587849 P50623 P32468 UBC9 CDC12 0.126 23712011 P50623 P32497 UBC9 NIP1 0.126 23712011 P50623 P32526 UBC9 KAR9 0.671 18832349 P50623 P32597 UBC9 STH1 0.126 23712011 P50623 P32892 UBC9 DRS1 0.126 23712011 P50623 P33122 UBC9 TYE7 0.126 23712011 P50623 P36015 UBC9 YKT6 0.126 23712011 P50623 P36121 UBC9 RPC37 0.126 23712011 P50623 P36160 UBC9 RPF2 0.126 23712011 P50623 P37838 UBC9 NOP4 0.126 23712011 P50623 P37898 UBC9 AAP1 0.126 23712011 P50623 P38129 UBC9 TAF5 0.126 23712011 P50623 P38226 UBC9 CST26 0.126 23712011 P50623 P38249 UBC9 RPG1 0.126 23712011 P50623 P38427 UBC9 TSL1 0.126 23712011 P50623 P38629 UBC9 RFC3 0.126 23712011 P50623 P38687 UBC9 SRP68 0.126 23712011 P50623 P38688 UBC9 SRP72 0.126 23712011 P50623 P38691 UBC9 KSP1 0.126 23712011 P50623 P38828 UBC9 LSM12 0.126 23712011 P50623 P38903 UBC9 RTS1 0.126 23712011 P50623 P38904 UBC9 SPP41 0.126 23712011 P50623 P39011 UBC9 BEM4 0.183 10688190 P50623 P39522 UBC9 ILV3 0.126 23712011 P50623 P39744 UBC9 NOC2 0.126 23712011 P50623 P39936 UBC9 TIF4632 0.126 23712011 P50623 P39955 UBC9 SAP1 0.126 23712011 P50623 P39960 UBC9 BEM2 0.126 23712011 P50623 P40010 UBC9 NUG1 0.126 23712011 P50623 P40215 UBC9 NDE1 0.126 23712011 P50623 P40984 UBC9 HUS5 0.309 8668125 P50623 P40991 UBC9 NOP2 0.126 23712011 P50623 P42945 UBC9 UTP10 0.126 23712011 P50623 P43123 UBC9 QRI1 0.126 23712011 P50623 P43621 UBC9 RET2 0.126 23712011 P50623 P45818 UBC9 ROK1 0.126 23712011 P50623 P50623 UBC9 UBC9 0.523 10688190,21518767 P53067 P50623 KAP114 UBC9 0.309 22562154 P53199 P50623 ERG26 UBC9 0.126 23712011 P53261 P50623 NOP7 UBC9 0.126 23712011 P53883 P50623 NOP13 UBC9 0.126 23712011 P53914 P50623 KRE33 UBC9 0.126 23712011 P53978 P50623 HEF3 UBC9 0.126 23712011 P54861 P50623 DNM1 UBC9 0.126 23712011 P63279 P50623 UBE2I UBC9 0.309 8668125 Q00684 P50623 CDC14 UBC9 0.183 23712011 Q00764 P50623 TPS1 UBC9 0.126 23712011 Q02892 P50623 NOG1 UBC9 0.126 23712011 Q03195 P50623 RLI1 UBC9 0.126 23712011 Q03388 P50623 VPS72 UBC9 0.126 23712011 Q03532 P50623 HAS1 UBC9 0.126 23712011 Q03718 P50623 NSE5 UBC9 0.126 14690591 Q03761 P50623 TAF12 UBC9 0.126 23712011 Q03973 P50623 HMO1 UBC9 0.126 23712011 Q04062 P50623 RPN9 UBC9 0.126 23712011 Q04175 P50623 SXM1 UBC9 0.126 23712011 Q04461 P50623 Q04461 UBC9 0.126 23712011 Q04600 P50623 TMA64 UBC9 0.126 23712011 Q04660 P50623 ERB1 UBC9 0.126 23712011 Q05022 P50623 RRP5 UBC9 0.126 23712011 Q05080 P50623 HOF1 UBC9 0.126 23712011 Q05123 P50623 ARP9 UBC9 0.126 23712011 Q06151 P50623 DCS1 UBC9 0.126 23712011 Q06205 P50623 FPR4 UBC9 0.126 23712011 Q06217 P50623 SMD2 UBC9 0.126 23712011 Q06624 P50623 AOS1 UBC9 0.523 15738391,21209884 Q06698 P50623 Q06698 UBC9 0.126 23712011 Q07381 P50623 TSR1 UBC9 0.126 23712011 Q08208 P50623 NOP12 UBC9 0.126 23712011 Q08746 P50623 RRS1 UBC9 0.126 23712011 Q08962 P50623 NIP7 UBC9 0.126 23712011 Q12117 P50623 MRH1 UBC9 0.126 23712011 Q12166 P50623 LEU9 UBC9 0.126 23712011 Q12216 P50623 NFI1 UBC9 0.925 22705796,23571759,24753409,20516210,23395907,23443663,18499666 Q12305 P50623 RDL1 UBC9 0.126 23712011 Q12389 P50623 DBP10 UBC9 0.126 23712011 Q06340 P50623 ESC2 UBC9 0.309 19158389 P53901 P50623 INN1 UBC9 0.309 22623719 Q04195 P50623 SIZ1 UBC9 0.974 22705796,11577116,16204216,11572779,23443663,19748360,16109721,23571759,11587849,24753409