PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SSA2 UBP1 16429126,19536198 intact exp UBP1 NAB2 19840948 biogrid exp TUB1 UBP1 16429126 intact exp UBP1 DRS1 16554755 intact exp SSB1 UBP1 16429126,19536198 intact exp SIN3 UBP1 16429126 intact exp UBP1 RMI1 i2d exp URA2 UBP1 16429126 intact exp UBP1 OLA1 16429126 intact exp FAS2 UBP1 16429126 intact exp GFA1 UBP1 16429126 intact exp UBP1 ERB1 16554755 biogrid,i2d,mint,intact exp PRP22 UBP1 16554755 biogrid,i2d,mint,intact exp UBP1 RPT1 16429126 intact exp UBP1 VAM6 25026036 biogrid exp TUB2 UBP1 16429126 intact exp aI2 UBP1 i2d exp VMA2 UBP1 16429126 intact exp VMA1 UBP1 16429126 intact exp UBP1 RLM1 16554755 biogrid,i2d,mint,intact exp RPS31 UBP1 2050695,1429680 biogrid exp RPL40B UBP1 2050695,1429680 biogrid exp UBP1 GIS2 21232131 biogrid exp HSC82 UBP1 19536198 intact exp UBP1 ERR3 i2d exp SSA1 UBP1 16429126,19536198,26217697 biogrid,intact exp UBP1 PDS1 22072716 biogrid exp ATP2 UBP1 16429126 intact exp UBP1 PUF3 26493364 biogrid exp SSA3 UBP1 19536198 intact exp UBP1 SIS1 19536198 intact exp UBP1 EGD2 i2d exp CDC25 UBP1 i2d exp FAS1 UBP1 16429126 intact exp CDC19 UBP1 16429126 intact exp UBP1 PSA1 16429126 intact exp UBP1 HRQ1 16554755 biogrid,i2d,mint,intact exp UBP1 Uncharacterized membrane protein YBR220C i2d exp UBP1 MKT1 16554755 biogrid,i2d,mint,intact exp UBP1 ELF1 i2d exp SBP1 UBP1 23222640 biogrid exp TDH3 UBP1 16429126 intact exp UBP1 SPC98 i2d exp UBP1 SSE1 16429126,19536198 intact exp RFA1 UBP1 25719602 biogrid exp SRS2 UBP1 15964827 biogrid exp UBP1 RPL5 16429126 intact exp MES1 UBP1 i2d exp TEF1, TEF2 UBP1 16429126 intact exp ADH1 UBP1 16429126 intact exp UBP1 SMC4 i2d exp UBP1 UBC7 14690591, 23023127 intact exp, pred UBP1 YDJ1 19536198, 23023127 intact exp, pred UBP1 UBP2 23023127 pred UBP1 DOA4 23023127 pred UBP1 UBP3 23023127 pred UBP1 UBI4 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P0CH08 P25037 enzymatic study 2050695 direct interaction X 2 P0CH08 P25037 enzymatic study 2050695 direct interaction X 2 P0CH08 P25037 enzymatic study 1429680 direct interaction X 2 P0CG63 P25037 affinity chromatography technology 23749301 physical association X 2 P0CG63 P25037 affinity chromatography technology 23793018 physical association X 2 P0CG63 P25037 affinity chromatography technology 21427232 physical association X 2 P12954 P25037 two hybrid 15964827 direct interaction X 2 P25037 W4YHN9 enzymatic study 22072716 direct interaction X 2 P25037 P40316 enzymatic study 22072716 direct interaction X 2 P25037 P05759 enzymatic study 2050695 direct interaction X 2 P25037 P05759 enzymatic study 1429680 direct interaction X 2 P25037 Q12224 affinity chromatography technology 16554755 physical association X 2 P25037 P40850 affinity chromatography technology 16554755 physical association X 2 P25037 Q05549 affinity chromatography technology 16554755 physical association X 2 P25037 P24384 affinity chromatography technology 16554755 physical association X 2 P25037 Q04660 affinity chromatography technology 16554755 physical association X 2 P25037 inferred by author 16554755 association C 7 P25037 tandem affinity purification 16429126 association C 5 P25037 P40850 tandem affinity purification 16554755 physical association X 2 P25037 Q12224 tandem affinity purification 16554755 physical association X 2 P25037 P25294 tandem affinity purification 19536198 association X 2 P25037 P11484 tandem affinity purification 19536198 association X 2 P25037 tandem affinity purification 16429126 association C 15 P25037 tandem affinity purification 16429126 association C 18 P10592 P25037 tandem affinity purification 19536198 association X 2 P32589 P25037 tandem affinity purification 19536198 association X 2 P15108 P25037 tandem affinity purification 19536198 association X 2 P10591 P25037 tandem affinity purification 19536198 association X 2 P25037 Q02159 two hybrid array 14690591 physical association X 2 P25037 P24384 tandem affinity purification 16554755 physical association X 2 P25037 P24384 tandem affinity purification 16554755 physical association X 2 P25037 P24384 tandem affinity purification 16554755 physical association X 2 P25037 Q04660 tandem affinity purification 16554755 physical association X 2 P25037 Q04660 tandem affinity purification 16554755 physical association X 2 P25037 Q05549 tandem affinity purification 16554755 physical association X 2 P25037 P24384 tandem affinity purification 16554755 physical association X 2 P25037 Q04660 tandem affinity purification 16554755 physical association X 2 P25037 P09435 tandem affinity purification 19536198 association X 2 P25037 P25491 tandem affinity purification 19536198 association X 2

PPI - HINT Gene A Gene B PMID Method Quality RPS31 UBP1 2050695,1429680 0415,0415 LC RPL40A UBP1 2050695,1429680 0415,0415 LC RPL40B UBP1 2050695,1429680 0415,0415 LC SRS2 UBP1 15964827 0018 LC RFA1 UBP1 25719602 0018 LC UBP1 PDS1 22072716 0415 LC UBP1 UBC7 14690591 0397 LC ADH1 UBP1 16429126 0676 HT TDH3 UBP1 16429126 0676 HT CDC19 UBP1 16429126 0676 HT ATP2 UBP1 16429126 0676 HT TUB2 UBP1 16429126 0676 HT TEF1|TEF2 UBP1 16429126 0676 HT FAS1 UBP1 16429126 0676 HT URA2 UBP1 16429126 0676 HT SSA3 UBP1 19536198 0676 HT TUB1 UBP1 16429126 0676 HT SSA1 UBP1 19536198,16429126,26217697 0676,0676,0004 HT,LC SSA2 UBP1 19536198,16429126 0676,0676 HT SSB1 UBP1 19536198,16429126 0676,0676 HT GFA1 UBP1 16429126 0676 HT HSC82 UBP1 19536198 0676 HT VMA2 UBP1 16429126 0676 HT VMA1 UBP1 16429126 0676 HT FAS2 UBP1 16429126 0676 HT SIN3 UBP1 16429126 0676 HT PRP22 UBP1 16554755,16554755 0676,0004 HT UBP1 SIS1 19536198 0676 HT UBP1 YDJ1 19536198 0676 HT UBP1 RPL5 16429126 0676 HT UBP1 NAB2 19840948 0004 LC UBP1 SSE1 19536198,16429126 0676,0676 HT UBP1 DRS1 16554755 0363 HT UBP1 RPT1 16429126 0676 HT UBP1 OLA1 16429126 0676 HT UBP1 MKT1 16554755,16554755 0676,0004 HT UBP1 PSA1 16429126 0676 HT UBP1 ERB1 16554755,16554755 0676,0004 HT UBP1 HRQ1 16554755,16554755 0676,0004 HT UBP1 RLM1 16554755,16554755 0676,0004 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P25037 P22336 UBP1 RFA1 0.309 25719602 P25037 P24384 UBP1 PRP22 0.332 16554755 P25037 P00330 UBP1 ADH1 0.126 16429126 P25037 P00359 UBP1 TDH3 0.126 16429126 P25037 P00549 UBP1 CDC19 0.126 16429126 P25037 P00830 UBP1 ATP2 0.126 16429126 P25037 P02557 UBP1 TUB2 0.126 16429126 P25037 P02994 UBP1 TEF2 0.126 16429126 P25037 P07149 UBP1 FAS1 0.126 16429126 P25037 P07259 UBP1 URA2 0.126 16429126 P25037 P09435 UBP1 SSA3 0.126 19536198 P25037 P09733 UBP1 TUB1 0.126 16429126 P25037 P14742 UBP1 GFA1 0.126 16429126 P25037 P16140 UBP1 VMA2 0.126 16429126 P25037 P17255 UBP1 VMA1 0.126 16429126 P25037 P19097 UBP1 FAS2 0.126 16429126 P25037 P22579 UBP1 SIN3 0.126 16429126 P25294 P25037 SIS1 UBP1 0.126 19536198 P26321 P25037 RPL5 UBP1 0.126 16429126 P33299 P25037 RPT1 UBP1 0.126 16429126 P38219 P25037 OLA1 UBP1 0.126 16429126 P40316 P25037 PDS1 UBP1 0.309 22072716 P41940 P25037 PSA1 UBP1 0.126 16429126 Q02159 P25037 UBC7 UBP1 0.126 14690591 Q04660 P25037 ERB1 UBP1 0.332 16554755 P25491 P25037 YDJ1 UBP1 0.126 19536198 P25037 P10080 UBP1 SBP1 0.126 23222640 P25037 P10591 UBP1 SSA1 0.332 19536198,26217697,16429126 P25037 P12954 UBP1 SRS2 0.183 15964827 P25037 P05759 UBP1 RPS31 0.523 2050695,1429680 P40850 P25037 MKT1 UBP1 0.236 16554755 P25037 P0CH08 UBP1 RPL40A 0.523 2050695,1429680 P25037 P0CH09 UBP1 RPL40B 0.523 2050695,1429680 P25037 P10592 UBP1 SSA2 0.236 16429126,19536198 P25037 P11484 UBP1 SSB1 0.236 16429126,19536198 Q12224 P25037 RLM1 UBP1 0.236 16554755 P32505 P25037 NAB2 UBP1 0.126 19840948 P32589 P25037 SSE1 UBP1 0.236 16429126,19536198 P32892 P25037 DRS1 UBP1 0.126 16554755 P25037 P15108 UBP1 HSC82 0.126 19536198 P53849 P25037 GIS2 UBP1 0.126 21232131 Q07807 P25037 PUF3 UBP1 0.126 Q05549 P25037 HRQ1 UBP1 0.236 16554755