PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CDC34 HSP78 19536198 intact exp CDC34 PHO89 i2d exp CDC34 WRS1 i2d exp CDC34 SGD1 i2d exp CDC34 CDC73 i2d exp CDC34 URH1 i2d exp CDC34 FLX1 i2d exp CDC34 VTC2 i2d exp CDC34 DEF1 i2d exp CDC34 HMT1 23706744 biogrid,intact exp CDC34 BDH1 i2d exp CDC34 MEP3 16554755 biogrid,i2d,mint,intact exp SSC1 CDC34 19536198 intact exp CDC34 VPS70 i2d exp POX1 CDC34 i2d exp CDC34 Putative uncharacterized protein YBL077W i2d exp CDC34 GNT1 i2d exp HTA1 CDC34 i2d exp CDC34 APJ1 19536198 intact exp CDC34 CCT2 19536198 intact exp CDC34 PMA2 i2d exp CDC34 VMA13 i2d exp CDC34 CCT6 19536198 intact exp CDC34 PSH1 25183013 biogrid exp CDC34 SRL4 i2d exp SSA1 CDC34 19536198 intact exp ILV1 CDC34 i2d exp CDC34 SFH1 i2d exp RPL40B CDC34 16554755 biogrid,i2d exp CDC34 HSP60 19536198 intact exp CDC34 GIS2 21232131 biogrid exp TDH2 CDC34 i2d exp CDC34 YSP3 i2d exp SCP160 CDC34 i2d exp PHO2 CDC34 i2d exp SBP1 CDC34 23222640 biogrid exp CDC34 RUP1 i2d exp CDC34 SIP5 i2d exp CDC34 FAR1 11080155 biogrid exp CDC34 CCT8 19536198 intact exp CDC34 CST6 i2d exp CDC34 MTC2 i2d exp CDC34 JJJ1 19536198 intact exp CDC34 MCM6 i2d exp CDC34 SLM5 i2d exp CDC34 RFM1 i2d exp CDC34 CRT10 16554755 biogrid,i2d,mint,intact exp CDC34 CRF1 i2d exp CDC34 RPB10 i2d exp RPL40A CDC34 12861024 i2d,dip exp CDC34 TEL1 i2d exp CDC34 COF1 i2d exp CDC34 BUD8 i2d exp CDC34 HSC82 19536198 intact exp CDC34 UBA3 i2d exp CDC34 PIC2 i2d exp CDC34 DRS2 16554755 biogrid,i2d,mint,intact exp RPS31 CDC34 i2d exp CDC34 MET4 21453497 biogrid exp CDC34 F-box protein YDR306C i2d exp CDC34 CIT3 i2d exp SSB1 CDC34 19536198 intact exp CDC34 RPM2 i2d exp CDC34 BMH2 i2d exp CDC34 RTT102 i2d exp UBI4 CDC34 7862115,21453497,16554755 biogrid,i2d,mint,intact exp CDC34 LRS4 21664583 biogrid exp CDC34 HSP10 19536198 intact exp CDC34 Putative lipase YJR107W i2d exp CDC34 SHE3 i2d exp SSA3 CDC34 19536198 intact exp CDC34 TRM9 i2d exp CDC34 MIP1 i2d exp CDC34 SSL1 i2d exp CDC34 NGG1 i2d exp CDC34 Uncharacterized protein YHR138C i2d exp CDC34 HSP104 19536198 intact exp CDC34 SVF1-like protein YDR222W i2d exp SSA2 CDC34 19536198 intact exp CDC34 S-formylglutathione hydrolase, FGH i2d exp CDC34 JEM1 19536198 intact exp CDC34 GDS1 i2d exp CDC34 SAM50 i2d exp CDC34 SSE1 19536198 intact exp CDC34 LAS1 i2d exp CDC34 SPT21 25228766 biogrid exp CDC34 DJP1 19536198 i2d,intact exp CDC34 ULA1 i2d exp CDC34 SSE2 19536198 intact exp CDC34 MDM10 i2d exp CDC34 SSB2 19536198 intact exp CDC34 SPB4 21825077 biogrid exp CDC34 CKA1 21453497, 23023127 biogrid exp, ortho, pred CDC34 SKP1 9346239,16554755,9499404,9346238, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred CDC34 UBC12 23023127 i2d exp, ortho, pred CDC34 CDC34 7862115,21453497,17562869,7929378,20194622,13678584,12861024,8383676,10213692,14747994,17114057, 23023127 biogrid,dip exp, ortho, pred CDC34 CKA2 21453497, 23023127 biogrid exp, ortho, pred CDC34 UBA1 12861024,22949505,17114057, 23023127 biogrid exp, ortho, pred CDC34 PRE7 23023127 i2d exp, pred CDC34 CLN2 7835341, 23023127 biogrid,i2d exp, pred CDC34 ETR1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 RPB9 11283351, 23023127 i2d,mint,intact,dip exp, pred CDC34 SCJ1 19536198, 23023127 intact exp, pred CDC34 RTT101 16554755,18704118, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 ESA1 19303850, 23023127 biogrid exp, pred CDC34 PRE5 23023127 i2d exp, pred CDC34 PRE8 23023127 i2d exp, pred CDC34 POL12 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 CDC53 16554755,9499404,8943317,12861024,19763088,8756727,10582239,10213692,9346239,9461595,18206966,9346238, 23023127 biogrid,i2d,mint,intact,dip exp, pred CDC34 SWE1 16319894,9716410, 23023127 biogrid exp, pred CDC34 NAM7 18087042,18676617, 23023127 biogrid exp, pred CDC6 CDC34 10512865, 23023127 biogrid,i2d exp, pred CDC34 RNR1 23023127 i2d exp, pred CDC34 SIS1 19536198, 23023127 intact exp, pred CDC34 CBF2 7651401, 23023127 biogrid exp, pred CDC34 FOX2 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 RUB1 23023127 i2d exp, pred CDC34 SIN4 10688190, 23023127 biogrid,i2d,mint,intact,dip exp, pred CDC9 CDC34 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 GRR1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC4 CDC34 18054791,17562869,9636170,23645675,8943317,16338374,9346239,10213692,9461595,20832729,17114057,20581844, 23023127 biogrid,i2d,dip exp, pred CDC34 SAF1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 CAK1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 MET30 9716410,16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 XRN1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 GDH2 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 RTG2 16554755, 23023127 biogrid,i2d,mint,intact exp, pred CDC34 MMS1 16554755, 23023127 biogrid,mint,intact exp, pred CDC34 HRT1 9285816,20542006,22328159,10385629,12553912,24316736,20194622,13678584,19945379,21098119,10213692,14747994,17574027,9346238, 23023127 biogrid,i2d,dip exp, pred CDC34 UBC7 14690591, 23023127 intact exp, pred CDC34 SIC1 9334303,21453497, 23023127 biogrid exp, pred CDC34 PRE4 23023127 i2d exp, pred CDC34 CFD1 ortho CDC34 RAD54 ortho CDC34 RAD51 ortho CDC34 RDI1 ortho CDC34 RBG2 ortho CDC34 ESS1 ortho CDC34 UBC4 23023127 ortho, pred CDC34 PPH22 23023127 pred CDC34 PEX4 23023127 pred CDC34 CDC48 23023127 pred CDC25 CDC34 23023127 pred CDC34 MOT2 23023127 pred CDC34 UBC5 23023127 pred CDC34 MPE1 23023127 pred CDC34 PRE3 23023127 pred CDC34 SMT3 23023127 pred CDC34 ELC1 23023127 pred CDC34 SCL1 23023127 pred CDC34 BUL2 23023127 pred CDC34 UBC9 23023127 pred CDC34 RPN2 23023127 pred CDC34 RFC1 23023127 pred CDC34 CDC23 23023127 pred CDC34 POL30 23023127 pred CDC34 ATG8 23023127 pred PRI1 CDC34 23023127 pred CDC34 UBC6 23023127 pred CDC34 RAD53 23023127 pred CDC34 PHO85 23023127 pred CDC34 Putative truncated guanine nucleotide exchange factor YLL017W 23023127 pred CDC34 DSK2 23023127 pred CDC34 RFA2 23023127 pred CDC34 YRB1 23023127 pred CDC34 URM1 23023127 pred CDC34 SMD1 23023127 pred CDC34 MCM5 23023127 pred CDC34 RPN12 23023127 pred CDC34 PRE6 23023127 pred TOP2 CDC34 23023127 pred CDC34 NAP1 23023127 pred CDC34 HSL1 23023127 pred CDC34 PRI2 23023127 pred CDC34 SHP1 23023127 pred CDC34 RFA1 23023127 pred CDC34 UBX7 23023127 pred CDC34 DMA2 23023127 pred CDC34 RAD23 23023127 pred CDC16 CDC34 23023127 pred CDC34 RNR4 23023127 pred CDC34 TUL1 23023127 pred CDC34 SMI1 23023127 pred CDC34 RSP5 23023127 pred CDC34 UBX5 23023127 pred CDC34 RFA3 23023127 pred CDC34 DBF4 23023127 pred RAD6 CDC34 23023127 pred CDC34 MUB1 23023127 pred CDC34 CDH1 23023127 pred CDC34 UBX3 23023127 pred CDC34 UBC8 23023127 pred CDC34 RSC8 23023127 pred CDC34 TOR2 23023127 pred CDC34 CDC40 23023127 pred CDC7 CDC34 23023127 pred CDC34 UBC11 23023127 pred CDC34 SGT1 23023127 pred CDC34 PRE2 23023127 pred CDC34 RIM1 23023127 pred CDC34 UFD4 23023127 pred CDC34 GLC7 23023127 pred CDC34 DOC1 23023127 pred CDC34 RPN4 23023127 pred CDC34 TRX2 23023127 pred CDC34 APC2 23023127 pred CDC34 BRE5 23023127 pred CDC34 RFC5 23023127 pred MCM1 CDC34 23023127 pred CDC34 PRE10 23023127 pred CDC34 AOS1 23023127 pred CDC34 HUB1 23023127 pred CDC34 PRP19 23023127 pred CDC34 SLA1 23023127 pred CDC34 PUP2 23023127 pred CDC34 SNF7 23023127 pred CDC34 PUP1 23023127 pred CDC34 ORC1 23023127 pred CDC34 ULP1 23023127 pred CDC34 CHS5 23023127 pred CDC34 CDC27 23023127 pred CDC34 RPT1 23023127 pred CDC34 UBI4 23023127 pred CDC34 CDC20 23023127 pred RNR2 CDC34 23023127 pred CDC34 DMA1 23023127 pred CDC34 HRR25 23023127 pred RHO1 CDC34 23023127 pred CDC34 UBX6 23023127 pred CDC28 CDC34 23023127 pred CDC34 PEX10 23023127 pred CDC34 CDC5 23023127 pred CDC34 CKB2 23023127 pred RAD18 CDC34 23023127 pred CDC34 UBC1 23023127 pred CDC34 RPN11 23023127 pred CDC34 YDJ1 23023127 pred CDC34 UBA2 23023127 pred CDC34 POB3 23023127 pred CDC34 PUP3 23023127 pred CDC24 CDC34 23023127 pred CDC34 PRE1 23023127 pred CDC34 PPH21 23023127 pred CDC34 APC11 23023127 pred CDC34 ATG12 23023127 pred CDC34 POL31 23023127 pred CDC34 MMS2 23023127 pred CDC34 SAD1 23023127 pred CDC34 UBP6 23023127 pred CDC34 UBC13 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P14682 - 9461595 - C 3 P14682 P27999 - 11283351 - X 2 P14682 P32259 - 10688190 - X 2 P14682 P52286 - 9499404 - X 2 P14682 P39014 - 9716410 - X 2 P14682 P38634 - 7954792 - X 2 P0CG63 P14682 - 8922273 - X 2 P14682 P22515 affinity chromatography technology 22949505 physical association X 2 P14682 P22515 affinity chromatography technology 22949505 physical association X 2 P14682 P07834 pull down 20581844 direct interaction X 2 P14682 P07834 pull down 9636170 direct interaction X 2 P14682 P07834 pull down 18054791 direct interaction X 2 P14682 P07834 affinity chromatography technology 9461595 physical association X 2 P14682 P07834 affinity chromatography technology 8943317 physical association X 2 P14682 P52286 pull down 9346239 direct interaction X 2 P14682 P07834 pull down 9346239 direct interaction X 2 P14682 P52286 affinity chromatography technology 9499404 physical association X 2 P14682 P32944 enzymatic study 9716410 direct interaction X 2 P14682 P32504 enzymatic study 7651401 direct interaction X 2 P14682 P07834 biochemical 9461595 colocalization X 2 P14682 enzymatic study 1651925 direct interaction X 2 P14682 Q5E9F8 enzymatic study 1651925 direct interaction X 2 P14682 P62803 enzymatic study 1651925 direct interaction X 2 P14682 P52286 affinity chromatography technology 9346238 physical association X 2 P14682 P07834 pull down 9461595 direct interaction X 2 P14682 P07834 enzymatic study 10213692 direct interaction X 2 P14682 Q12161 affinity chromatography technology 25183013 physical association X 2 P14682 P07834 pull down 20832729 direct interaction X 2 P14682 P07834 pull down 16338374 direct interaction X 2 P14682 P07834 pull down 17114057 direct interaction X 2 P14682 P07834 pull down 17562869 direct interaction X 2 P14682 P07834 pull down 23645675 direct interaction X 2 P14682 P22515 enzymatic study 12861024 direct interaction X 2 P14682 P22515 enzymatic study 17114057 direct interaction X 2 P14682 P39524 affinity chromatography technology 16554755 physical association X 2 P14682 P52286 affinity chromatography technology 16554755 physical association X 2 P14682 P22147 affinity chromatography technology 16554755 physical association X 2 P14682 P0CH08 affinity chromatography technology 16554755 physical association X 2 P14682 Q02207 affinity chromatography technology 16554755 physical association X 2 P14682 P53390 affinity chromatography technology 16554755 physical association X 2 P14682 P32944 enzymatic study 16319894 direct interaction X 2 P14682 P30771 pull down 18676617 direct interaction X 2 P14682 P32389 enzymatic study 21453497 direct interaction X 2 P14682 P32259 two hybrid 10688190 direct interaction X 2 Q06211 P14682 affinity chromatography technology 16554755 physical association X 2 P25808 P14682 affinity chromatography technology 21825077 physical association X 2 P14682 P14682 affinity chromatography technology 12861024 physical association X 2 P14682 Q12018 affinity chromatography technology 9499404 physical association X 2 P14682 Q12018 affinity chromatography technology 9346238 physical association X 2 P14682 Q12018 affinity chromatography technology 10213692 physical association X 2 P14682 Q12018 affinity chromatography technology 8756727 physical association X 2 P14682 Q08273 affinity chromatography technology 10385629 physical association X 2 P14682 Q08273 pull down 17574027 direct interaction X 2 P14682 Q08273 pull down 20542006 direct interaction X 2 P14682 Q08273 pull down 20634314 direct interaction X 2 P14682 Q08273 pull down 22328159 direct interaction X 2 P14682 P14682 affinity chromatography technology 7929378 physical association X 2 P14682 Q12018 affinity chromatography technology 9461595 physical association X 2 P14682 Q12018 affinity chromatography technology 8943317 physical association X 2 P14682 P39014 affinity chromatography technology 9716410 physical association X 2 P14682 Q12018 pull down 9346239 direct interaction X 2 P14682 P38634 pull down 9334303 direct interaction X 2 P14682 Q12018 affinity chromatography technology 10582239 physical association X 2 P14682 P14682 enzymatic study 20194622 direct interaction X 2 P14682 Q08273 pull down 20194622 direct interaction X 2 P14682 P0CG48 pull down 23801757 direct interaction X 2 P14682 P21268 enzymatic study 11080155 direct interaction X 2 P14682 P09119 enzymatic study 10512865 direct interaction X 2 P14682 P38634 enzymatic study 9334303 direct interaction X 2 P14682 P14682 enzymatic study 8383676 direct interaction X 2 P14682 P20438 enzymatic study 7835341 direct interaction X 2 P14682 Q12018 biochemical 9461595 colocalization X 2 P14682 P47050 pull down 24209620 direct interaction X 2 P14682 Q08273 pull down 24316736 direct interaction X 2 P14682 P14682 enzymatic study 13678584 direct interaction X 2 P14682 P14682 enzymatic study 14747994 direct interaction X 2 P14682 P14682 enzymatic study 7862115 direct interaction X 2 P14682 P14682 pull down 7929378 direct interaction X 2 P14682 Q12018 pull down 8756727 direct interaction X 2 P14682 Q12018 pull down 9461595 direct interaction X 2 P14682 Q08273 pull down 10213692 direct interaction X 2 P14682 Q08273 affinity chromatography technology 10213692 physical association X 2 P14682 P14682 enzymatic study 10213692 direct interaction X 2 P14682 P35209 affinity chromatography technology 25228766 physical association X 2 P14682 P14682 enzymatic study 12861024 direct interaction X 2 P14682 Q12018 affinity chromatography technology 12861024 physical association X 2 P14682 P14682 enzymatic study 17114057 direct interaction X 2 P14682 Q08273 pull down 12553912 direct interaction X 2 P14682 Q08273 pull down 13678584 direct interaction X 2 P14682 Q08273 pull down 14747994 direct interaction X 2 P14682 Q08273 pull down 9346238 direct interaction X 2 P14682 Q08273 pull down 9285816 direct interaction X 2 P14682 P62877 pull down 10579999 direct interaction X 2 P14682 Q08273 pull down 21098119 direct interaction X 2 P14682 P38071 affinity chromatography technology 16554755 physical association X 2 P14682 P38352 affinity chromatography technology 16554755 physical association X 2 P14682 Q12018 affinity chromatography technology 16554755 physical association X 2 P14682 P33327 affinity chromatography technology 16554755 physical association X 2 P14682 P43568 affinity chromatography technology 16554755 physical association X 2 P14682 P32608 affinity chromatography technology 16554755 physical association X 2 P14682 P47050 affinity chromatography technology 16554755 physical association X 2 P14682 Q08226 affinity chromatography technology 16554755 physical association X 2 P14682 P38121 affinity chromatography technology 16554755 physical association X 2 P14682 P04819 affinity chromatography technology 16554755 physical association X 2 P14682 P39014 affinity chromatography technology 16554755 physical association X 2 P14682 Q12018 affinity chromatography technology 17200106 physical association X 2 P14682 P32608 affinity chromatography technology 17200106 physical association X 2 P14682 P47050 affinity chromatography technology 17200106 physical association X 2 P14682 P14682 enzymatic study 17562869 direct interaction X 2 P14682 Q12018 affinity chromatography technology 18206966 physical association X 2 P14682 P68400-2 enzymatic study 18418079 direct interaction X 2 P14682 P47050 pull down 18704118 direct interaction X 2 P14682 Q08649 enzymatic study 19303850 direct interaction X 2 P14682 Q12018 pull down 19763088 direct interaction X 2 P14682 Q08273 fluorescent resonance energy transfer 19945379 direct interaction X 2 P14682 Q08273 x-ray crystallography 19945379 association X 2 P14682 P14682 enzymatic study 21453497 direct interaction X 2 P14682 Q04087 affinity chromatography technology 21664583 physical association X 2 P14682 P38634 enzymatic study 21453497 direct interaction X 2 P14682 P15790 enzymatic study 21453497 direct interaction X 2 P14682 P19454 enzymatic study 21453497 direct interaction X 2 P0CG63 P14682 affinity chromatography technology 23749301 physical association X 2 P0CG63 P14682 affinity chromatography technology 17644757 physical association X 2 P0CG63 P14682 enzymatic study 7862115 direct interaction X 2 P0CG63 P14682 affinity chromatography technology 23793018 physical association X 2 P0CG63 P14682 affinity chromatography technology 12872131 physical association X 2 P0CG63 P14682 affinity chromatography technology 21427232 physical association X 2 P0CG63 P14682 enzymatic study 21453497 direct interaction X 2 P14682 enzymatic study 1651925 direct interaction X 2 P24814 P14682 affinity chromatography technology 16554755 physical association X 2 P14682 coimmunoprecipitation 9346238 - C 4 P14682 P27999 two hybrid pooling approach 11283351 physical association X 2 P14682 P32259 two hybrid 10688190 physical association X 2 P14682 P07834 affinity chromatography technology 8943317 physical association X 2 P14682 P07834 affinity chromatography technology 9461595 physical association X 2 P14682 P14682 coimmunoprecipitation 12861024 physical association Y 1 P14682 P52286 coimmunoprecipitation 13678584 physical association X 2 P14682 P52286 affinity chromatography technology 9346238 physical association X 2 P14682 P62987 mass spectrometry studies of complexes 19956254 direct interaction X 2 P14682 Q12018 affinity chromatography technology 8943317 physical association X 2 P14682 Q12018 coimmunoprecipitation 9346238 physical association X 2 P14682 Q12018 coimmunoprecipitation 12861024 physical association X 2 P14682 Q12018 coimmunoprecipitation 10213692 physical association X 2 P14682 P05759 molecular sieving 12861024 physical association X 2 P14682 P05759 comigration in sds page 10213692 physical association X 2 P14682 P05759 coimmunoprecipitation 12861024 physical association X 2 P14682 Q08273 coimmunoprecipitation 10213692 physical association X 2 P14682 inferred by author 16554755 association C 12 P14682 anti tag coimmunoprecipitation 9499404 association C 6 P14682 anti tag coimmunoprecipitation 9499404 association C 4 P14682 anti tag coimmunoprecipitation 9499404 association C 4 P14682 P32259 two hybrid 10688190 physical association X 2 P14682 P27999 two hybrid fragment pooling approach 11283351 physical association X 2 P14682 Q02159 two hybrid array 14690591 physical association X 2 P14682 P22147 tandem affinity purification 16554755 physical association X 2 P14682 P22147 tandem affinity purification 16554755 physical association X 2 P14682 P22147 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 Q02207 tandem affinity purification 16554755 physical association X 2 P14682 P22147 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P53390 tandem affinity purification 16554755 physical association X 2 P14682 P53390 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P52286 tandem affinity purification 16554755 physical association X 2 P14682 P39524 tandem affinity purification 16554755 physical association X 2 P14682 P39524 tandem affinity purification 16554755 physical association X 2 P14682 Q02207 tandem affinity purification 16554755 physical association X 2 P14682 P22147 tandem affinity purification 16554755 physical association X 2 P14682 P22147 tandem affinity purification 16554755 physical association X 2 P14682 P22147 tandem affinity purification 16554755 physical association X 2 P14682 P40564 tandem affinity purification 19536198 association X 2 P14682 P25303 tandem affinity purification 19536198 association X 2 P14682 P53863 tandem affinity purification 19536198 association X 2 P14682 P19882 tandem affinity purification 19536198 association X 2 P14682 P10591 tandem affinity purification 19536198 association X 2 P14682 P11484 tandem affinity purification 19536198 association X 2 P14682 P0CS90 tandem affinity purification 19536198 association X 2 P14682 P33416 tandem affinity purification 19536198 association X 2 P14682 P15108 tandem affinity purification 19536198 association X 2 P14682 P31539 tandem affinity purification 19536198 association X 2 P14682 P38910 tandem affinity purification 19536198 association X 2 Q06211 P14682 tandem affinity purification 16554755 physical association X 2 Q06211 P14682 tandem affinity purification 16554755 physical association X 2 Q06211 P14682 tandem affinity purification 16554755 physical association X 2 Q06211 P14682 tandem affinity purification 16554755 physical association X 2 Q06211 P14682 tandem affinity purification 16554755 physical association X 2 P32589 P14682 tandem affinity purification 19536198 association X 2 P14682 P38352 tandem affinity purification 16554755 physical association X 2 P14682 P38121 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P04819 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P04819 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P04819 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P39014 tandem affinity purification 16554755 physical association X 2 P14682 Q08226 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P32608 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P47050 tandem affinity purification 16554755 physical association X 2 P14682 P38352 tandem affinity purification 16554755 physical association X 2 P14682 P38352 tandem affinity purification 16554755 physical association X 2 P14682 Q08226 tandem affinity purification 16554755 physical association X 2 P14682 Q08226 tandem affinity purification 16554755 physical association X 2 P14682 Q08226 tandem affinity purification 16554755 physical association X 2 P14682 P38071 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P38071 tandem affinity purification 16554755 physical association X 2 P14682 P43568 tandem affinity purification 16554755 physical association X 2 P14682 P43568 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 Q12018 tandem affinity purification 16554755 physical association X 2 P14682 P33327 tandem affinity purification 16554755 physical association X 2 P14682 P33327 tandem affinity purification 16554755 physical association X 2 P14682 P47050 pull down 18704118 physical association X 2 P14682 P40358 tandem affinity purification 19536198 association X 2 P14682 P25294 tandem affinity purification 19536198 association X 2 P14682 P53940 tandem affinity purification 19536198 association X 2 P14682 P09435 tandem affinity purification 19536198 association X 2 P14682 P32590 tandem affinity purification 19536198 association X 2 P14682 P10592 tandem affinity purification 19536198 association X 2 P14682 P39079 tandem affinity purification 19536198 association X 2 P14682 P39076 tandem affinity purification 19536198 association X 2 P14682 P47079 tandem affinity purification 19536198 association X 2 P14682 P40150 tandem affinity purification 19536198 association X 2 P14682 P38074 dihydrofolate reductase reconstruction 23706744 physical association X 2 P14682 Q12018 anti tag coimmunoprecipitation 9499404 physical association X 2 P0CG63 P14682 tandem affinity purification 16554755 physical association X 2 P0CG63 P14682 tandem affinity purification 16554755 physical association X 2 P24814 P14682 tandem affinity purification 16554755 physical association X 2 P24814 P14682 tandem affinity purification 16554755 physical association X 2 P24814 P14682 tandem affinity purification 16554755 physical association X 2 P14682 confirmational text mining - - C 4 P14682 confirmational text mining - - C 4 P14682 P38290 interaction detection method - - X 2 P14682 Q03919 interaction detection method 9545234 - X 2 P14682 P52286 interaction detection method 9491072 - X 2 P14682 P52286 coimmunoprecipitation 9499404 - X 2 P14682 P07834 interaction detection method 9499404 - X 2 P14682 P07834 affinity chromatography technology 9461595 - X 2 P14682 P52491 interaction detection method 9545234 - X 2 P14682 P32259 two hybrid 10688190 - X 2 P14682 Q12059 interaction detection method 9545234 - X 2 P14682 P30283 interaction detection method - - X 2 P14682 P27999 two hybrid 11283351 - X 2 P14682 confirmational text mining - - C 4 P14682 Q12018 interaction detection method 9499404 - X 2 P14682 Q12018 affinity chromatography technology 8756727,9461595,9499404 - X 2 P14682 P39014 interaction detection method 9716410 - X 2 P14682 P39014 coimmunoprecipitation 9716410 - X 2 P14682 P09119 interaction detection method 9312054 - X 2 P14682 P38634 interaction detection method 9334303 - X 2 P14682 P20438 interaction detection method 8756727 - X 2 P14682 Q99344 interaction detection method 9545234 - X 2 P0CG63 P14682 interaction detection method 8922273 - X 2 P0CG63 P14682 cross-linking study 8922273 - X 2 P24814 P14682 interaction detection method 9491072 - X 2

PPI - HINT Gene A Gene B PMID Method Quality RPS31 CDC34 12861024,12861024,10213692 0019,0071,0808 LC CDC4 CDC34 9461595,9461595,10213692,9461595 0401,0004,0415,0096 LC CDC6 CDC34 10512865 0415 LC UBI4 CDC34 21453497,8922273,21453497,7862115 0096,0030,0415,0415 LC CDC34 CDC34 17114057,20194622,7862115,14747994,12861024,12861024,13678584,8383676,17562869,21453497,10213692,12861024 0415,0415,0415,0415,0019,0004,0415,0415,0415,0415,0415,0415 LC CDC34 CKA1 21453497 0415 LC CDC34 CKA2 21453497 0415 LC CDC34 CLN1 10213692 0415 LC CDC34 CLN2 7835341 0415 LC CDC34 FAR1 11080155 0415 LC CDC34 UBA1 12861024,17114057 0415,0415 LC CDC34 RPB9 11283351,11283351,11283351 0018,0399,0398 HT CDC34 SIN4 10688190,10688190 0397,0018 HT CDC34 MET4 21453497 0415 LC CDC34 CBF2 7651401 0415 LC CDC34 SWE1 9716410,16319894 0415,0415 LC CDC34 HMT1 23706744,23706744 0111,0090 LC CDC34 SIC1 9346239,9285816,9285816,9346238,21453497,9334303,9334303 0415,0096,0415,0415,0415,0096,0415 LC CDC34 MET30 9716410,9716410 0004,0019 LC CDC34 SKP1 9499404,9499404,13678584,9499404 0019,0007,0019,0004 LC CDC34 UBC7 14690591 0397 LC CDC34 HRT1 10213692,19945379,10213692,10213692,19945379 0019,0114,0004,0096,0055 LC CDC34 ESA1 19303850 0415 LC CDC34 CDC53 9461595,9461595,12861024,10213692,10213692,12861024,9346238,9461595,9346238 0401,0004,0019,0004,0019,0004,0004,0096,0019 LC CDC9 CDC34 16554755,16554755 0676,0004 HT CDC4 CDC34 9461595,8943317,9636170,9461595,18054791,20832729,17562869,17114057,16338374,9461595,9346239,23645675,20581844 0401,0004,0096,0004,0096,0096,0096,0096,0096,0096,0096,0096,0096 LC SSA3 CDC34 19536198 0676 HT UBI4 CDC34 21453497,16554755,21453497,17562869 0096,0676,0415,0004 LC,HT RPL40A CDC34 16554755 0004 HT RPL40B CDC34 16554755 0004 HT SSC1 CDC34 19536198 0676 HT SSA1 CDC34 19536198 0676 HT SSA2 CDC34 19536198 0676 HT SSB1 CDC34 19536198 0676 HT CDC34 CDC34 7929378,12861024,12861024,7929378,12861024 0004,0019,0004,0096,0415 LC CDC34 HSC82 19536198 0676 HT CDC34 HSP60 19536198 0676 HT CDC34 XRN1 16554755,16554755 0676,0004 HT CDC34 UBA1 22949505 0004 LC CDC34 GRR1 16554755,16554755 0676,0004 HT CDC34 SIS1 19536198 0676 HT CDC34 SCJ1 19536198 0676 HT CDC34 SPB4 21825077 0004 LC CDC34 NAM7 18676617 0096 LC CDC34 HSP104 19536198 0676 HT CDC34 SSE1 19536198 0676 HT CDC34 SSE2 19536198 0676 HT CDC34 RTG2 17200106,16554755,16554755 0004,0676,0004 HT CDC34 GDH2 16554755,16554755 0676,0004 HT CDC34 HSP78 19536198 0676 HT CDC34 SPT21 25228766 0004 HT CDC34 ETR1 16554755,16554755 0676,0004 HT CDC34 POL12 16554755,16554755 0676,0004 HT CDC34 SAF1 16554755,16554755 0676,0004 HT CDC34 SIC1 9285816,9285816,9334303,9334303 0096,0415,0096,0415 LC CDC34 HSP10 19536198 0676 HT CDC34 MET30 16554755,9716410,16554755,9716410 0004,0004,0676,0019 HT,LC CDC34 CCT2 19536198 0676 HT CDC34 CCT6 19536198 0676 HT CDC34 DRS2 16554755,16554755 0676,0004 HT CDC34 RSP5 26508657 0004 LC CDC34 SSB2 19536198 0676 HT CDC34 JEM1 19536198 0676 HT CDC34 DJP1 19536198 0676 HT CDC34 CAK1 16554755,16554755,16554755 0363,0676,0004 HT CDC34 RTT101 16554755,17200106,16554755,18704118 0004,0004,0676,0096 HT,LC CDC34 CCT8 19536198 0676 HT CDC34 SKP1 16554755,9499404,9346238,9499404,9499404,9346239,16554755 0676,0019,0004,0007,0004,0096,0004 HT,LC CDC34 MEP3 16554755,16554755 0676,0004 HT CDC34 JJJ1 19536198 0676 HT CDC34 APJ1 19536198 0676 HT CDC34 FOX2 16554755,16554755 0676,0004 HT CDC34 LRS4 21664583 0004 LC CDC34 MMS1 16554755,16554755 0676,0004 HT CDC34 CRT10 16554755,16554755 0676,0004 HT CDC34 HRT1 10213692,9346238,9285816,20542006,10213692,12553912,22328159,21098119,10213692,13678584,14747994,20194622,24316736,17574027,10385629 0019,0096,0096,0096,0004,0096,0096,0096,0096,0096,0096,0096,0096,0096,0004 LC CDC34 CDC53 9461595,8756727,9346239,17200106,8756727,9461595,12861024,18206966,19763088,10213692,16554755,9499404,10213692,8943317,16554755,12861024,9346238,10582239,9461595,9346238,9499404 0401,0004,0096,0004,0096,0004,0019,0004,0096,0004,0676,0007,0019,0004,0004,0004,0004,0004,0096,0019,0004 LC,HT CDC34 PSH1 25183013 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P22515 P14682 UBA1 CDC34 0.702 17114057,22949505,12861024 P15790 P14682 CKA1 CDC34 0.309 21453497 P25294 P14682 SIS1 CDC34 0.126 19536198 P14682 P0CG63 CDC34 UBI4 0.583 16554755,7862115,21453497 P14682 P0CS90 CDC34 SSC1 0.126 19536198 P14682 P10080 CDC34 SBP1 0.126 23222640 P14682 P10591 CDC34 SSA1 0.126 19536198 P14682 P10592 CDC34 SSA2 0.126 19536198 P14682 P11484 CDC34 SSB1 0.126 19536198 P14682 P09435 CDC34 SSA3 0.126 19536198 P14682 P04819 CDC34 CDC9 0.332 16554755 P33327 P14682 GDH2 CDC34 0.236 16554755 P38121 P14682 POL12 CDC34 0.236 16554755 P38352 P14682 SAF1 CDC34 0.236 16554755 P38634 P14682 SIC1 CDC34 0.523 21453497,9334303 P39014 P14682 MET30 CDC34 0.236 16554755 P14682 P07834 CDC34 CDC4 0.976 18054791,20832729,17562869,10213692,8943317,16338374,20581844,23645675,9461595,17114057 P52286 P14682 SKP1 CDC34 0.659 9499404,9346238,13678584,16554755 P38074 P14682 HMT1 CDC34 0.286 23706744 P61864 P14682 RPL40A CDC34 0.096 10213692,12861024 Q12018 P14682 CDC53 CDC34 0.945 9499404,10582239,18206966,16554755,10213692,19763088,8943317,9346238,9461595,12861024 P27999 P14682 RPB9 CDC34 0.236 11283351 P25808 P14682 SPB4 CDC34 0.126 21825077 P38071 P14682 ETR1 CDC34 0.332 16554755 P30771 P14682 NAM7 CDC34 0.396 18676617,18087042 P32259 P14682 SIN4 CDC34 0.332 10688190 P32589 P14682 SSE1 CDC34 0.126 19536198 P32590 P14682 SSE2 CDC34 0.126 19536198 P32608 P14682 RTG2 CDC34 0.332 16554755 P39076 P14682 CCT2 CDC34 0.126 19536198 P39079 P14682 CCT6 CDC34 0.126 19536198 P39524 P14682 DRS2 CDC34 0.332 16554755 P32944 P14682 SWE1 CDC34 0.436 9716410,16319894 P39940 P14682 RSP5 CDC34 0.126 26508657 P40150 P14682 SSB2 CDC34 0.126 19536198 P43568 P14682 CAK1 CDC34 0.332 16554755 P40564 P14682 DJP1 CDC34 0.126 19536198 P47050 P14682 RTT101 CDC34 0.636 16554755,18704118 P47079 P14682 CCT8 CDC34 0.126 19536198 P62877 P14682 RBX1 CDC34 0.309 10579999 P15108 P14682 HSC82 CDC34 0.126 19536198 P14682 P0CH08 CDC34 RPL40A 0.126 16554755 P14682 P09119 CDC34 CDC6 0.309 10512865 P14682 P0CH09 CDC34 RPL40B 0.126 16554755 P14682 P14682 CDC34 CDC34 0.977 20194622,13678584,7862115,17562869,10213692,14747994,21453497,8383676,7929378,17114057,12861024 P21268 P14682 FAR1 CDC34 0.309 11080155 P19882 P14682 HSP60 CDC34 0.126 19536198 P20438 P14682 CLN2 CDC34 0.309 7835341 P24814 P14682 GRR1 CDC34 0.236 16554755 P25303 P14682 SCJ1 CDC34 0.126 19536198 P62803 P14682 P62803 CDC34 0.309 1651925 P31539 P14682 HSP104 CDC34 0.126 19536198 P32504 P14682 CBF2 CDC34 0.309 7651401 P32389 P14682 MET4 CDC34 0.309 21453497 P40358 P14682 JEM1 CDC34 0.126 19536198 P33416 P14682 HSP78 CDC34 0.126 19536198 P38910 P14682 HSP10 CDC34 0.126 19536198 P53940 P14682 APJ1 CDC34 0.126 19536198 P53390 P14682 MEP3 CDC34 0.236 16554755 Q02159 P14682 UBC7 CDC34 0.126 14690591 Q08273 P14682 HRT1 CDC34 0.996 20194622,21098119,13678584,22328159,19945379,17574027,9285816,9346238,20542006,12553912,10213692,24316736,14747994 Q12161 P14682 PSH1 CDC34 0.21 25183013 Q5E9F8 P14682 H3F3B CDC34 0.309 1651925 P68400 P14682 CSNK2A1 CDC34 0.309 18418079 P19454 P14682 CKA2 CDC34 0.309 21453497 Q02207 P14682 FOX2 CDC34 0.332 16554755 Q06211 P14682 MMS1 CDC34 0.332 16554755 P53849 P14682 GIS2 CDC34 0.126 21232131 P53863 P14682 JJJ1 CDC34 0.126 19536198 Q04087 P14682 LRS4 CDC34 0.21 21664583 Q08226 P14682 CRT10 CDC34 0.332 16554755 Q08649 P14682 ESA1 CDC34 0.183 19303850 P22147 P14682 XRN1 CDC34 0.332 16554755