PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HSP82 MTC5 11805837 dip exp MTC5 SOV1 11805837 dip exp PIL1 MTC5 25073740 intact exp RPT3 MTC5 11805837 dip exp CDC48 MTC5 25073740 intact exp NPR3 MTC5 21454883,25073740 biogrid,intact exp MKT1 MTC5 25073740 intact exp Uncharacterized protein YHR033W MTC5 11805837 biogrid,mint,intact,dip exp EFT1, EFT2 MTC5 11805837 dip exp ALD4 MTC5 11805837 dip exp VMA1 MTC5 25073740 intact exp VMA2 MTC5 25073740,11805837 intact,dip exp GFA1 MTC5 11805837 dip exp TDH1 MTC5 11805837 dip exp ENO1 MTC5 11805837 dip exp UFD4 MTC5 i2d exp MTC5 HSP42 11805837 dip exp CAB3 MTC5 14690591 intact exp MIR1 MTC5 25073740 intact exp SSC1 MTC5 25073740,11805837 intact,dip exp SSB1 MTC5 19536198 intact exp SSA2 MTC5 19536198 intact exp HMT1 MTC5 14690591 intact exp SSB2 MTC5 23332755 biogrid exp PFK2 MTC5 25073740 intact exp SSA4 MTC5 11805837 dip exp ILV2 MTC5 11805837 dip exp SSA3 MTC5 19536198,16554755,11805837 biogrid,i2d,mint,intact,dip exp SHY1 MTC5 23979592 biogrid exp MTC5 NOP58 25073740 intact exp SNF1 MTC5 11805837 dip exp ATP1 MTC5 25073740 intact exp MTC5 PUF3 26493364 biogrid exp MTC5 VAM6 25026036 biogrid exp ACT1 MTC5 25073740 intact exp ARG3 MTC5 11805837 dip exp IML1 MTC5 21454883,25073740 biogrid,intact exp SDC25 MTC5 19841731 mint,intact exp UBC7 MTC5 14690591 intact exp CHC1 MTC5 25073740 intact exp GAL1 MTC5 11805837 dip exp SEC26 MTC5 25073740 intact exp MTC5 CWC2 14690591 intact exp ADE5,7 MTC5 25073740 intact exp ALD6 MTC5 25073740 intact exp LEU2 MTC5 11805837 dip exp CCT8 MTC5 11805837 dip exp MDJ1 MTC5 11805837 biogrid,mint,intact,dip exp TFB1 MTC5 i2d exp MLP1 MTC5 24152732 biogrid exp HSP26 MTC5 11805837 dip exp HSP60 MTC5 25073740,11805837 intact,dip exp NAB2 MTC5 19840948 biogrid exp URA2 MTC5 25073740 intact exp ATP2 MTC5 25073740 intact exp GAL10 MTC5 11805837 dip exp SRS2 MTC5 15964827 biogrid exp ECM10 MTC5 19536198 intact exp GPM1 MTC5 25073740 intact exp GAL7 MTC5 11805837 dip exp PFK1 MTC5 25073740 intact exp SEA4 MTC5 21454883,25073740 biogrid,intact exp MTC5 SEC13 21454883,10688190,25073740, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred SEH1 MTC5 21454883,25073740,18046405,11805837, 23023127 biogrid,mint,intact,dip exp, ortho, pred MTC5 RTC1 21454883,25073740, 23023127 biogrid,intact exp, pred FMP10 MTC5 11805837, 23023127 biogrid,mint,intact,dip exp, pred RFA3 MTC5 11805837, 23023127 biogrid,mint,intact,dip exp, pred MTC5 Uncharacterized protein YOR093C 16554755, 23023127 biogrid,i2d,mint,intact exp, pred MTC5 THI21 11805837, 23023127 biogrid,mint,intact,dip exp, pred RNQ1 MTC5 11805837, 23023127 biogrid,mint,intact,dip exp, pred MTC5 YKU80 11805837, 23023127 biogrid,intact,dip exp, pred KIN2 MTC5 20489023, 23023127 biogrid,mint,intact exp, pred SUI1 MTC5 11283351, 23023127 i2d,mint,intact,dip exp, pred MCK1 MTC5 20489023, 23023127 biogrid,mint,intact exp, pred POX1 MTC5 11805837, 23023127 biogrid,mint,intact,dip exp, pred NPR2 MTC5 21454883,25073740,11805837, 23023127 biogrid,mint,intact,dip exp, pred CDC33 MTC5 11805837, 23023127 biogrid,mint,intact,dip exp, pred FUS1 MTC5 19841731, 23023127 mint,intact exp, pred CCT6 MTC5 11805837, 23023127 biogrid,mint,intact,dip exp, pred CPR6 MTC5 11805837, 23023127 biogrid,mint,intact,dip exp, pred GLE2 MTC5 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q03897 - 11805837 - C 12 Q03897 - 11805837 - C 11 Q03897 - 11805837 - C 15 P32911 Q03897 - 11283351 - X 2 Q04491 Q03897 - 10688190 - X 2 P39079 Q03897 - 11805837 - X 2 P07260 Q03897 affinity chromatography technology 11805837 physical association X 2 P0CG63 Q03897 affinity chromatography technology 23749301 physical association X 2 P0CG63 Q03897 biochemical 23583075 association X 2 Q08975 Q03897 affinity chromatography technology 11805837 physical association X 2 P40098 Q03897 affinity chromatography technology 11805837 physical association X 2 P21965 Q03897 affinity chromatography technology 20489023 physical association X 2 P25367 Q03897 affinity chromatography technology 11805837 physical association X 2 Q08281 Q03897 affinity chromatography technology 21454883 physical association X 2 Q08281 Q03897 affinity chromatography technology 21454883 physical association X 2 P53691 Q03897 affinity chromatography technology 11805837 physical association X 2 P39923 Q03897 affinity chromatography technology 21454883 physical association X 2 P39923 Q03897 affinity chromatography technology 21454883 physical association X 2 P39923 Q03897 affinity chromatography technology 11805837 physical association X 2 Q04437 Q03897 affinity chromatography technology 11805837 physical association X 2 P53011 Q03897 affinity chromatography technology 21454883 physical association X 2 P53011 Q03897 affinity chromatography technology 21454883 physical association X 2 P53011 Q03897 affinity chromatography technology 18046405 physical association X 2 P53011 Q03897 affinity chromatography technology 11805837 physical association X 2 Q04491 Q03897 affinity chromatography technology 21454883 physical association X 2 Q04491 Q03897 two hybrid 10688190 direct interaction X 2 P38742 Q03897 affinity chromatography technology 21454883 physical association X 2 P38742 Q03897 affinity chromatography technology 21454883 physical association X 2 P38690 Q03897 affinity chromatography technology 11805837 physical association X 2 P26755 Q03897 affinity chromatography technology 11805837 physical association X 2 P12954 Q03897 two hybrid 15964827 direct interaction X 2 P47170 Q03897 affinity chromatography technology 21454883 physical association X 2 P47170 Q03897 affinity chromatography technology 21454883 physical association X 2 P13711 Q03897 affinity chromatography technology 11805837 physical association X 2 P35191 Q03897 affinity chromatography technology 11805837 physical association X 2 P39079 Q03897 affinity chromatography technology 11805837 physical association X 2 P13186 Q03897 affinity chromatography technology 20489023 physical association X 2 P40150 Q03897 biochemical 23332755 association X 2 Q12275 Q03897 affinity chromatography technology 16554755 physical association X 2 Q03897 P09435 affinity chromatography technology 16554755 physical association X 2 P38164 Q03897 affinity chromatography technology 21454883 physical association X 2 P38164 Q03897 affinity chromatography technology 21454883 physical association X 2 Q03897 anti tag coimmunoprecipitation 11805837 - C 12 Q03897 anti tag coimmunoprecipitation 11805837 - C 11 Q03897 anti tag coimmunoprecipitation 11805837 - C 30 Q03897 anti tag coimmunoprecipitation 11805837 - C 37 Q03897 anti tag coimmunoprecipitation 11805837 - C 76 P19882 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P07260 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P07342 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P00924 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P46367 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P14742 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q08975 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P40098 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P04173 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P25367 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12329 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P53691 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P22202 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03897 P47079 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03897 P15992 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04437 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03897 anti tag coimmunoprecipitation 11805837 - C 35 P06782 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P16140 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P32911 Q03897 two hybrid pooling approach 11283351 physical association X 2 P00360 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P08431 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P04385 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04491 Q03897 two hybrid 10688190 physical association X 2 P38690 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P02829 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P04397 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P26755 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P32324 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P13711 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P35191 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P39079 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04748 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03897 P05150 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03897 P09435 anti tag coimmunoprecipitation 11805837 physical association X 2 P33298 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 P0CS90 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03897 affinity chromatography technology 25073740 association C 5 Q03897 affinity chromatography technology 25073740 association C 5 Q03897 anti tag coimmunoprecipitation 11805837 association C 15 Q03897 affinity chromatography technology 25073740 association C 9 Q03897 anti tag coimmunoprecipitation 20489023 association C 35 Q03897 affinity chromatography technology 25073740 association C 36 Q02159 Q03897 two hybrid array 14690591 physical association X 2 P0CF34 Q03897 peptide array 19841731 direct interaction X 2 Q03897 affinity chromatography technology 25073740 association C 7 Q03897 affinity chromatography technology 25073740 association C 24 Q03897 affinity chromatography technology 25073740 association C 27 Q03897 anti tag coimmunoprecipitation 20489023 association C 8 Q03897 affinity chromatography technology 25073740 association C 5 Q03897 anti tag coimmunoprecipitation 20489023 association C 35 Q03897 affinity chromatography technology 25073740 association C 10 Q03897 pull down 14690591 association C 22 Q03897 affinity chromatography technology 25073740 association C 3 Q03897 affinity chromatography technology 25073740 association C 18 Q03897 affinity chromatography technology 25073740 association C 24 Q03897 pull down 14690591 association C 17 Q03897 anti tag coimmunoprecipitation 11805837 association C 12 Q03897 affinity chromatography technology 25073740 association C 4 Q03897 anti tag coimmunoprecipitation 11805837 association C 11 Q03897 affinity chromatography technology 25073740 association C 8 Q03897 affinity chromatography technology 25073740 association C 8 Q03897 affinity chromatography technology 25073740 association C 8 Q03897 cross-linking study 25073740 physical association C 8 Q03897 cosedimentation through density gradient 25073740 physical association C 8 P10592 Q03897 tandem affinity purification 19536198 association X 2 P32911 Q03897 two hybrid fragment pooling approach 11283351 physical association X 2 P11484 Q03897 tandem affinity purification 19536198 association X 2 Q04491 Q03897 two hybrid 10688190 physical association X 2 P11710 Q03897 peptide array 19841731 direct interaction X 2 P39079 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12275 Q03897 inferred by author 16554755 association X 2 Q12275 Q03897 tandem affinity purification 16554755 physical association X 2 P39987 Q03897 tandem affinity purification 19536198 association X 2 P38074 Q03897 two hybrid array 14690591 physical association X 2 Q03897 P09435 tandem affinity purification 16554755 physical association X 2 Q03897 P09435 tandem affinity purification 19536198 association X 2 Q03897 mass spectrometry studies of complexes 11805837 - C 12 Q03897 mass spectrometry studies of complexes 11805837 - C 38 Q03897 mass spectrometry studies of complexes 11805837 - C 13 Q03897 mass spectrometry studies of complexes 11805837 - C 13 P32911 Q03897 two hybrid 11283351 - X 2 Q04491 Q03897 two hybrid 10688190 - X 2

PPI - HINT Gene A Gene B PMID Method Quality SDC25 MTC5 19841731 0081 HT FUS1 MTC5 19841731 0081 HT SRS2 MTC5 15964827 0018 LC SUI1 MTC5 11283351,11283351,11283351 0018,0399,0398 HT HMT1 MTC5 14690591 0397 LC SSB2 MTC5 23332755 0401 LC IML1 MTC5 25073740,25073740,25073740 0004,0029,0030 LC UBC7 MTC5 14690591 0397 LC MTC5 SEC13 10688190,10688190 0397,0018 HT TDH1 MTC5 11805837 0007 HT ATP2 MTC5 25073740 0004 LC ENO1 MTC5 11805837 0007 HT GPM1 MTC5 25073740 0004 LC HSP82 MTC5 11805837 0007 HT LEU2 MTC5 11805837 0007 HT GAL1 MTC5 11805837 0007 HT GAL10 MTC5 11805837 0007 HT ARG3 MTC5 11805837 0007 HT SNF1 MTC5 11805837 0007 HT ADE5,7 MTC5 25073740 0004 LC ATP1 MTC5 25073740 0004 LC URA2 MTC5 25073740 0004 LC CDC33 MTC5 11805837,11805837 0004,0007 HT ILV2 MTC5 11805837 0007 HT GAL7 MTC5 11805837 0007 HT SSA3 MTC5 19536198,16554755,11805837,16554755 0676,0676,0007,0004 HT SSC1 MTC5 25073740,11805837 0004,0007 LC,HT SSA2 MTC5 19536198 0676 HT SSB1 MTC5 19536198 0676 HT KIN2 MTC5 20489023,20489023 0007,0004 HT POX1 MTC5 11805837,11805837 0004,0007 HT GFA1 MTC5 11805837 0007 HT HSP26 MTC5 11805837 0007 HT VMA2 MTC5 25073740,11805837 0004,0007 LC,HT PFK1 MTC5 25073740 0004 LC PFK2 MTC5 25073740 0004 LC VMA1 MTC5 25073740 0004 LC HSP60 MTC5 25073740,11805837 0004,0007 LC,HT MCK1 MTC5 20489023,20489023 0007,0004 HT CHC1 MTC5 25073740 0004 LC SSA4 MTC5 11805837 0007 HT MIR1 MTC5 25073740 0004 LC RNQ1 MTC5 11805837,11805837 0004,0007 HT CDC48 MTC5 25073740 0004 LC RFA3 MTC5 11805837,11805837 0004,0007 HT EFT1|EFT2 MTC5 11805837 0007 HT NAB2 MTC5 19840948 0004 LC RPT3 MTC5 11805837 0007 HT MDJ1 MTC5 11805837,11805837 0004,0007 HT SEA4 MTC5 25073740,21454883 0004,0004 LC P38690 MTC5 11805837,11805837 0004,0007 HT NPR3 MTC5 25073740,21454883 0004,0004 LC CCT6 MTC5 11805837,11805837 0004,0007 HT NPR2 MTC5 11805837,25073740,11805837,21454883 0004,0004,0007,0004 HT,LC ECM10 MTC5 19536198 0676 HT FMP10 MTC5 11805837,11805837 0004,0007 HT SSB2 MTC5 23332755 0401 LC MKT1 MTC5 25073740 0004 LC SEC26 MTC5 25073740 0004 LC ALD4 MTC5 11805837 0007 HT CCT8 MTC5 11805837 0007 HT IML1 MTC5 25073740,25073740,21454883,25073740 0004,0029,0004,0030 LC SEH1 MTC5 11805837,25073740,11805837,21454883,18046405 0004,0004,0007,0004,0004 HT,LC PIL1 MTC5 25073740 0004 LC SHY1 MTC5 23979592 0004 LC CPR6 MTC5 11805837,11805837 0004,0007 HT ALD6 MTC5 25073740 0004 LC ACT1 MTC5 25073740 0004 LC MLP1 MTC5 24152732 0004 LC MTC5 YKU80 11805837,11805837 0004,0007 HT MTC5 SEC13 25073740,21454883 0004,0004 LC MTC5 SOV1 11805837 0007 HT MTC5 RTC1 25073740,21454883 0004,0004 LC MTC5 THI21 11805837,11805837 0004,0007 HT MTC5 Q12275 16554755,16554755,16554755 0363,0676,0004 HT MTC5 HSP42 11805837 0007 HT MTC5 NOP58 25073740 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q04437 Q03897 YKU80 MTC5 0.21 11805837 Q04491 Q03897 SEC13 MTC5 0.539 10688190,25073740,21454883 Q12046 Q03897 CWC2 MTC5 0.126 14690591 Q04748 Q03897 SOV1 MTC5 0.126 11805837 Q03897 P15992 MTC5 HSP26 0.126 11805837 Q12329 Q03897 HSP42 MTC5 0.126 11805837 Q03897 P0CF34 MTC5 SDC25 0.183 19841731 Q03897 P00924 MTC5 ENO1 0.126 11805837 Q03897 P11484 MTC5 SSB1 0.126 19536198 Q03897 P11710 MTC5 FUS1 0.183 19841731 Q03897 P02829 MTC5 HSP82 0.126 11805837 Q03897 P12398 MTC5 SSC1 0.126 11805837 Q03897 P12954 MTC5 SRS2 0.183 15964827 Q03897 P13186 MTC5 KIN2 0.286 20489023 Q03897 P00360 MTC5 TDH1 0.126 11805837 Q03897 P04173 MTC5 LEU2 0.126 11805837 Q03897 P04385 MTC5 GAL1 0.126 11805837 Q03897 P06782 MTC5 SNF1 0.126 11805837 Q03897 P38164 MTC5 SEA4 0.523 25073740,21454883 Q03897 P38742 MTC5 NPR3 0.523 25073740,21454883 Q03897 P47170 MTC5 IML1 0.636 25073740,21454883 Q08281 Q03897 RTC1 MTC5 0.523 25073740,21454883 Q12275 Q03897 Q12275 MTC5 0.332 16554755 Q03897 P36076 MTC5 CAB3 0.126 14690591 Q03897 P26755 MTC5 RFA3 0.236 11805837 Q03897 P32505 MTC5 NAB2 0.126 19840948 Q03897 P39079 MTC5 CCT6 0.376 11805837 Q03897 P32911 MTC5 SUI1 0.236 11283351 Q03897 P33298 MTC5 RPT3 0.126 11805837 Q03897 P46367 MTC5 ALD4 0.126 11805837 Q03897 P47079 MTC5 CCT8 0.126 11805837 Q03897 P19882 MTC5 HSP60 0.236 11805837,25073740 Q03897 Q02455 MTC5 MLP1 0.126 24152732 Q03897 P13711 MTC5 POX1 0.236 11805837 Q07468 Q03897 VAM6 MTC5 0.126 25026036 Q03897 P10592 MTC5 SSA2 0.126 19536198 Q03897 P0CS90 MTC5 SSC1 0.126 25073740 Q03897 P09435 MTC5 SSA3 0.376 16554755,11805837,19536198 Q03897 P05150 MTC5 ARG3 0.126 11805837 Q03897 P04397 MTC5 GAL10 0.126 11805837 Q03897 P00830 MTC5 ATP2 0.126 25073740 Q03897 P00950 MTC5 GPM1 0.126 25073740 Q03897 P08431 MTC5 GAL7 0.126 11805837 Q03897 P07259 MTC5 URA2 0.126 25073740 Q03897 P07244 MTC5 ADE5,7 0.126 25073740 Q03897 P07251 MTC5 ATP1 0.126 25073740 Q03897 P07342 MTC5 ILV2 0.126 11805837 Q03897 P07260 MTC5 CDC33 0.21 11805837 Q03897 P53011 MTC5 SEH1 0.597 11805837,25073740,18046405,21454883 Q03897 P17255 MTC5 VMA1 0.126 25073740 Q03897 P14742 MTC5 GFA1 0.126 11805837 Q03897 P16862 MTC5 PFK2 0.126 25073740 Q03897 P16140 MTC5 VMA2 0.236 11805837,25073740 Q03897 P16861 MTC5 PFK1 0.126 25073740 Q03897 P32324 MTC5 EFT2 0.126 11805837 Q03897 P23641 MTC5 MIR1 0.126 25073740 Q03897 P22137 MTC5 CHC1 0.126 25073740 Q03897 P25367 MTC5 RNQ1 0.236 11805837 Q03897 P25694 MTC5 CDC48 0.126 25073740 Q03897 P41810 MTC5 SEC26 0.126 25073740 Q03897 P38074 MTC5 HMT1 0.126 14690591 Q03897 P35191 MTC5 MDJ1 0.21 11805837 Q03897 P38690 MTC5 P38690 0.21 11805837 Q03897 P40850 MTC5 MKT1 0.126 25073740 Q03897 P39923 MTC5 NPR2 0.597 11805837,25073740,21454883 Q03897 P40098 MTC5 FMP10 0.21 11805837 Q03897 P39987 MTC5 ECM10 0.126 19536198 Q03897 Q02159 MTC5 UBC7 0.126 14690591 Q03897 P53252 MTC5 PIL1 0.126 25073740 Q03897 P60010 MTC5 ACT1 0.126 25073740 Q03897 P53691 MTC5 CPR6 0.236 11805837 Q03897 P54115 MTC5 ALD6 0.126 25073740 Q08975 Q03897 THI21 MTC5 0.21 11805837 Q12499 Q03897 NOP58 MTC5 0.126 25073740 Q03897 P21965 MTC5 MCK1 0.286 20489023 Q03897 P22202 MTC5 SSA4 0.126 11805837