PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus NAM7 PEX10 18087042 biogrid exp RIM1 PEX10 18467557 biogrid,i2d,mint,intact exp HSP82 PEX10 15766533 biogrid,i2d,intact exp PEX10 PUF3 26493364 biogrid exp PHO85 PEX10 16319894 biogrid,i2d exp SSZ1 PEX10 19536198 intact exp SSA2 PEX10 19536198 intact exp ERG6 PEX10 21748599 biogrid exp PEX18 PEX10 24034674 biogrid exp PEX10 PEX10 18644345,12876220, 23023127 biogrid,dip exp, ortho, pred PEX10 PEX15 12876220,16911527, 23023127 biogrid,intact,dip exp, pred PEX2 PEX10 19687296,22471590,12667447,22500805, 23023127 biogrid,intact exp, pred PEX8 PEX10 12667447, 23023127 intact exp, pred PEX12 PEX10 11370741,22471590,12667447,12876220,20655618, 23023127 biogrid,intact,dip exp, pred PEX17 PEX10 12667447, 23023127 biogrid,intact exp, pred PEX10 PEX11 22615397,18467557, 23023127 biogrid,i2d,mint,intact exp, pred UBC4 PEX10 22471590,24034674, 23023127 biogrid exp, pred PEX14 PEX10 12667447,22375831, 23023127 biogrid,intact exp, pred PEX5 PEX10 16849337,12667447,15456864, 23023127 biogrid,intact exp, pred PEX6 PEX10 16911527, 23023127 biogrid,intact exp, pred PEX13 PEX10 12667447,12876220,20655618,22500805, 23023127 biogrid,mint,intact,dip exp, pred UBC7 PEX10 14690591, 23023127 intact exp, pred PEX10 PEX19 12876220, 23023127 biogrid,dip exp, pred PEX22 PEX10 12876220, 23023127 biogrid,mint,intact,dip exp, pred PEX1 PEX10 16911527, 23023127 biogrid,intact exp, pred PEX4 PEX10 22471590,12876220,24034674, 23023127 biogrid,mint,intact,dip exp, pred PEX10 DNL4 ortho RPD3 PEX10 ortho UBC9 PEX10 23023127 ortho, pred UBC13 PEX10 23023127 pred PRP19 PEX10 23023127 pred DMA1 PEX10 23023127 pred UBI4 PEX10 23023127 pred UBC5 PEX10 23023127 pred UBC12 PEX10 23023127 pred PEX3 PEX10 23023127 pred CDC16 PEX10 23023127 pred TFB3 PEX10 23023127 pred PEX10 HRT1 23023127 pred PEX10 APC2 23023127 pred PEX7 PEX10 23023127 pred UBC8 PEX10 23023127 pred RAD18 PEX10 23023127 pred UBC11 PEX10 23023127 pred MPE1 PEX10 23023127 pred CDC34 PEX10 23023127 pred UBC1 PEX10 23023127 pred TUL1 PEX10 23023127 pred RAD6 PEX10 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P02829 Q05568 - 15766533 - X 2 P39718 Q05568 protein complementation assay 12876220 direct interaction X 2 A0A087WW00 Q05568 pull down 18644345 direct interaction X 2 P15731 Q05568 pull down 22471590 direct interaction X 2 P15731 Q05568 pull down 24034674 direct interaction X 2 P17157 Q05568 enzymatic study 16319894 direct interaction X 2 P38855 Q05568 enzymatic study 24034674 direct interaction X 2 Q05568 P80667 protein complementation assay 22500805 direct interaction X 2 Q05568 P80667 affinity chromatography technology 12667447 physical association X 2 Q05568 P35056 affinity chromatography technology 12667447 physical association X 2 Q05568 P35056 affinity chromatography technology 15456864 physical association X 2 Q05568 P35056 affinity chromatography technology 16849337 physical association X 2 Q05568 Q05568 enzymatic study 18644345 direct interaction X 2 Q05568 Q07418 protein complementation assay 12876220 direct interaction X 2 Q05568 P80667 protein complementation assay 12876220 direct interaction X 2 Q05568 Q05568 protein complementation assay 12876220 direct interaction X 2 Q05568 P80667 affinity chromatography technology 20655618 physical association X 2 Q12462 Q05568 protein complementation assay 18467557 direct interaction X 2 Q12462 Q05568 protein complementation assay 22615397 direct interaction X 2 P29340 Q05568 pull down 22471590 direct interaction X 2 P29340 Q05568 pull down 24034674 direct interaction X 2 P29340 Q05568 protein complementation assay 12876220 direct interaction X 2 P53112 Q05568 affinity chromatography technology 12667447 physical association X 2 P53112 Q05568 affinity chromatography technology 12667447 physical association X 2 P53112 Q05568 affinity chromatography technology 22375831 physical association X 2 P24004 Q05568 biochemical 16911527 colocalization X 2 Q04370 Q05568 affinity chromatography technology 12667447 physical association X 2 Q04370 Q05568 affinity chromatography technology 12667447 physical association X 2 Q04370 Q05568 biochemical 11370741 association X 2 Q04370 Q05568 pull down 22471590 direct interaction X 2 Q04370 Q05568 pull down 22471590 direct interaction X 2 Q04370 Q05568 protein complementation assay 12876220 direct interaction X 2 Q04370 Q05568 affinity chromatography technology 20655618 physical association X 2 P32800 Q05568 protein complementation assay 22500805 direct interaction X 2 P32800 Q05568 affinity chromatography technology 12667447 physical association X 2 P32800 Q05568 affinity chromatography technology 12667447 physical association X 2 P32800 Q05568 pull down 22471590 direct interaction X 2 P32800 Q05568 pull down 22471590 direct interaction X 2 P32800 Q05568 affinity chromatography technology 19687296 physical association X 2 P40155 Q05568 affinity chromatography technology 12667447 physical association X 2 P02829 Q05568 affinity chromatography technology 15766533 physical association X 2 P32445 Q05568 protein complementation assay 18467557 direct interaction X 2 Q05568 P33760 biochemical 16911527 colocalization X 2 Q08215 Q05568 biochemical 16911527 colocalization X 2 Q08215 Q05568 protein complementation assay 12876220 direct interaction X 2 P25087 Q05568 protein complementation assay 21748599 direct interaction X 2 P39718 Q05568 ubiquitin reconstruction 12876220 physical association X 2 Q05568 P80667 ubiquitin reconstruction 12876220 physical association X 2 Q05568 Q07418 ubiquitin reconstruction 12876220 physical association X 2 P29340 Q05568 coimmunoprecipitation 12876220 physical association X 2 P29340 Q05568 ubiquitin reconstruction 12876220 physical association X 2 P29340 Q05568 two hybrid 12876220 physical association X 2 Q04370 Q05568 coimmunoprecipitation 12876220 physical association X 2 Q04370 Q05568 ubiquitin reconstruction 12876220 physical association X 2 Q05568 Q05568 ubiquitin reconstruction 12876220 physical association Y 1 Q08215 Q05568 ubiquitin reconstruction 12876220 physical association X 2 Q05568 pull down 12667447 association C 5 Q05568 pull down 12667447 association C 5 Q05568 pull down 12667447 association C 8 Q05568 pull down 12667447 association C 6 Q05568 pull down 12667447 association C 6 Q05568 pull down 16911527 association C 5 Q05568 pull down 12667447 association C 6 Q05568 pull down 12667447 association C 6 Q05568 pull down 12667447 association C 6 Q05568 pull down 12667447 association C 6 Q05568 pull down 16911527 association C 6 Q05568 pull down 12667447 association C 8 Q05568 pull down 12667447 association C 8 Q05568 pull down 12667447 association C 8 Q05568 pull down 12667447 association C 8 Q05568 pull down 12667447 association C 8 Q05568 pull down 16911527 association C 7 Q05568 pull down 12667447 association C 4 Q05568 pull down 12667447 association C 3 Q05568 pull down 16911527 association C 8 Q05568 pull down 16911527 association C 8 P39718 Q05568 ubiquitin reconstruction 12876220 physical association X 2 Q05568 P80667 ubiquitin reconstruction 12876220 physical association X 2 Q05568 P80667 bimolecular fluorescence complementation 22500805 physical association X 2 Q05568 P80667 bimolecular fluorescence complementation 22500805 physical association X 2 Q05568 P80667 fluorescence microscopy 22500805 colocalization X 2 Q12462 Q05568 dihydrofolate reductase reconstruction 18467557 physical association X 2 P29340 Q05568 ubiquitin reconstruction 12876220 physical association X 2 Q05568 pull down 12667447 association C 6 Q05568 pull down 16911527 association C 9 Q05568 pull down 16911527 association C 9 Q05568 pull down 16911527 association C 9 Q05568 pull down 12667447 association C 5 Q05568 pull down 12667447 association C 5 Q05568 pull down 16911527 association C 6 Q05568 blue native page 12667447 physical association C 4 Q05568 pull down 12667447 association C 3 Q05568 pull down 12667447 association C 3 Q05568 pull down 12667447 association C 7 Q05568 pull down 12667447 association C 6 Q05568 pull down 12667447 association C 7 Q05568 pull down 12667447 association C 7 P10592 Q05568 tandem affinity purification 19536198 association X 2 Q04370 Q05568 blue native page 12667447 physical association X 2 Q04370 Q05568 blue native page 12667447 physical association X 2 Q04370 Q05568 pull down 12667447 physical association X 2 Q04370 Q05568 pull down 12667447 association X 2 P32800 Q05568 bimolecular fluorescence complementation 22500805 physical association X 2 P32800 Q05568 bimolecular fluorescence complementation 22500805 physical association X 2 P32800 Q05568 fluorescence microscopy 22500805 colocalization X 2 P32800 Q05568 bimolecular fluorescence complementation 22500805 physical association X 2 Q02159 Q05568 two hybrid array 14690591 physical association X 2 P02829 Q05568 affinity chromatography technology 15766533 physical association X 2 P32445 Q05568 dihydrofolate reductase reconstruction 18467557 physical association X 2 P38788 Q05568 tandem affinity purification 19536198 association X 2 Q06683 Q05568 interaction detection method 14764870 - X 2

PPI - HINT Gene A Gene B PMID Method Quality PHO85 PEX10 16319894 0415 LC PEX1 PEX10 16911527,16911527 0401,0096 LC ERG6 PEX10 21748599 0090 HT PEX4 PEX10 12876220,12876220,12876220,12876220 0090,0019,0018,0112 LC RIM1 PEX10 18467557,18467557 0111,0090 HT PEX2 PEX10 22500805,22500805,22500805 0090,0809,0416 LC PEX6 PEX10 16911527,16911527 0401,0096 LC PEX18 PEX10 24034674 0415 LC PEX22 PEX10 12876220,12876220 0112,0090 LC PEX17 PEX10 12667447,12667447,12667447 0096,0276,0004 LC PEX14 PEX10 12667447,12667447,12667447 0096,0276,0004 LC PEX13 PEX10 22500805,22500805,22500805,12876220,12876220 0090,0416,0809,0112,0090 LC UBC7 PEX10 14690591 0397 LC PEX12 PEX10 12876220,12876220,12667447,11370741,12876220,12667447,12667447 0090,0019,0004,0401,0112,0096,0276 LC PEX10 PEX10 12876220,18644345,12876220 0112,0415,0090 LC PEX10 PEX19 12876220,12876220 0112,0090 LC PEX10 PEX15 16911527,16911527,12876220,12876220 0401,0096,0112,0090 LC PEX10 PEX11 18467557,18467557,22615397 0111,0090,0090 HT,LC HSP82 PEX10 15766533 0004 LC SSA2 PEX10 19536198 0676 HT UBC4 PEX10 24034674,22471590 0096,0096 LC PEX1 PEX10 16911527,16911527 0401,0096 LC PEX4 PEX10 22471590,24034674 0096,0096 LC PEX2 PEX10 19687296,12667447,22471590,12667447 0004,0004,0096,0096 LC PEX6 PEX10 16911527,16911527 0401,0096 LC PEX5 PEX10 12667447,12667447,15456864,16849337 0096,0004,0004,0004 LC SSZ1 PEX10 19536198 0676 HT PEX17 PEX10 12667447,12667447,12667447 0096,0276,0004 LC PEX14 PEX10 12667447,12667447,12667447,22375831 0096,0276,0004,0004 LC PEX8 PEX10 12667447 0096 LC PEX13 PEX10 12667447,20655618,12667447 0004,0004,0096 LC PEX12 PEX10 12667447,22471590,11370741,20655618,12667447,12667447 0004,0096,0401,0004,0096,0276 LC PEX10 PEX15 16911527,16911527 0401,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q05568 P53248 PEX10 PEX8 0.21 12667447 Q05568 P24004 PEX10 PEX1 0.21 16911527 Q05568 P25087 PEX10 ERG6 0.183 21748599 Q05568 P17157 PEX10 PHO85 0.183 16319894 Q05568 P10592 PEX10 SSA2 0.126 19536198 Q05568 P15731 PEX10 UBC4 0.523 22471590,24034674 Q05568 P32800 PEX10 PEX2 0.888 12667447,19687296,22471590,22500805 Q05568 P40155 PEX10 PEX17 0.376 12667447 Q05568 P53112 PEX10 PEX14 0.61 12667447,22375831 Q05568 Q04370 PEX10 PEX12 0.899 12667447,12876220,20655618,22471590 Q05568 P29340 PEX10 PEX4 0.692 12876220,24034674,22471590 Q05568 P30771 PEX10 NAM7 0.126 18087042 Q05568 P32445 PEX10 RIM1 0.286 18467557 Q05568 P39718 PEX10 PEX22 0.286 12876220 Q05568 P33760 PEX10 PEX6 0.21 16911527 Q05568 P35056 PEX10 PEX5 0.376 12667447,15456864 Q07418 Q05568 PEX19 PEX10 0.21 12876220 Q12462 Q05568 PEX11 PEX10 0.286 18467557 Q08215 Q05568 PEX15 PEX10 0.354 16911527,12876220 Q05568 P02829 PEX10 HSP82 0.236 15766533 Q05568 P38855 PEX10 PEX18 0.309 24034674 Q05568 P38788 PEX10 SSZ1 0.126 19536198 Q05568 P80667 PEX10 PEX13 0.772 12667447,12876220,20655618,22500805 Q05568 P51668 PEX10 UBE2D1 0.309 18644345 Q05568 Q02159 PEX10 UBC7 0.126 14690591 Q05568 Q05568 PEX10 PEX10 0.436 12876220,18644345