PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBI4 GGA1 15039776 biogrid exp PSA1 GGA1 16429126 intact exp GGA1 PUF3 23409723 biogrid exp UBP6 GGA1 i2d exp KEX2 GGA1 23408788 biogrid exp SSB1 GGA1 16429126,19536198 intact exp MON2 GGA1 18418388 biogrid exp HSP104 GGA1 19536198 intact exp SSA1 GGA1 16429126, 23023127 intact exp, pred ARF1 GGA1 20601958,11124697, 23023127 biogrid,i2d exp, pred CHC1 GGA1 11689690,11408593, 23023127 biogrid exp, pred GGA1 HSP42 19536198, 23023127 intact exp, pred SSA2 GGA1 16429126, 23023127 intact exp, pred ARF2 GGA1 11124697,12221117, 23023127 biogrid,i2d exp, pred GGA1 VPS36 23023127 pred SEC21 GGA1 23023127 pred GGA2 GGA1 23023127 pred GGA1 VPS68 23023127 pred VPS20 GGA1 23023127 pred GGA1 ATG20 23023127 pred HSE1 GGA1 23023127 pred GGA1 APL4 23023127 pred GGA1 UBX3 23023127 pred STP22 GGA1 23023127 pred SEC28 GGA1 23023127 pred VPS27 GGA1 23023127 pred GGA1 VAM3 23023127 pred ENT3 GGA1 23023127 pred UBX7 GGA1 23023127 pred VPS60 GGA1 23023127 pred ENT5 GGA1 23023127 pred GGA1 TLG2 23023127 pred SHP1 GGA1 23023127 pred TUL1 GGA1 23023127 pred KAR2 GGA1 23023127 pred ATG8 GGA1 23023127 pred UBP2 GGA1 23023127 pred UBX6 GGA1 23023127 pred VPS4 GGA1 23023127 pred UBI4 GGA1 23023127 pred GGA1 UBX5 23023127 pred UBC4 GGA1 23023127 pred GGA1 HUB1 23023127 pred BRO1 GGA1 23023127 pred VTI1 GGA1 23023127 pred SNX41 GGA1 23023127 pred UBC8 GGA1 23023127 pred RAD23 GGA1 23023127 pred SSH4 GGA1 23023127 pred IST1 GGA1 23023127 pred EAR1 GGA1 23023127 pred GGA1 VPS5 23023127 pred GGA1 SRN2 23023127 pred VPS24 GGA1 23023127 pred PEP12 GGA1 23023127 pred DID4 GGA1 23023127 pred DSK2 GGA1 23023127 pred APS1 GGA1 23023127 pred DID2 GGA1 23023127 pred CDC16 GGA1 23023127 pred SDH8 GGA1 23023127 pred SSO2 GGA1 23023127 pred SNF7 GGA1 23023127 pred RSP5 GGA1 23023127 pred ATG12 GGA1 23023127 pred MVB12 GGA1 23023127 pred ATG3 GGA1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P19146 Q06336 - 11124697 - X 2 P11076 Q06336 - 11124697 - X 2 P22137 Q06336 affinity chromatography technology 11408593 physical association X 2 P22137 Q06336 pull down 11689690 direct interaction X 2 P19146 Q06336 two hybrid 11124697 direct interaction X 2 P19146 Q06336 affinity chromatography technology 11124697 physical association X 2 P19146 Q06336 two hybrid 12221117 direct interaction X 2 P0CG63 Q06336 two hybrid 15039776 direct interaction X 2 P0CG63 Q06336 affinity chromatography technology 23749301 physical association X 2 P0CG63 Q06336 affinity chromatography technology 23793018 physical association X 2 P0CG63 Q06336 affinity chromatography technology 12872131 physical association X 2 P0CG63 Q06336 affinity chromatography technology 15039776 physical association X 2 P0CG48 Q06336 pull down 17494868 direct interaction X 2 P48563 Q06336 affinity chromatography technology 18418388 physical association X 2 P11076 Q06336 two hybrid 11124697 direct interaction X 2 P11076 Q06336 affinity chromatography technology 11124697 physical association X 2 P11076 Q06336 x-ray crystallography 20601958 association X 2 P13134 Q06336 two hybrid 23408788 direct interaction X 2 Q06336 tandem affinity purification 16429126 association C 5 Q06336 P31539 tandem affinity purification 19536198 association X 2 Q06336 P0CG53 surface plasmon resonance 20150893 direct interaction X 2 P11484 Q06336 tandem affinity purification 19536198 association X 2 Q06336 Q12329 tandem affinity purification 19536198 association X 2 Q06336 P32486 interaction detection method 14764870 - X 2

PPI - HINT Gene A Gene B PMID Method Quality UBI4 GGA1 15039776,15039776 0004,0018 LC ARF1 GGA1 11124697,11124697,20601958 0018,0004,0114 LC KEX2 GGA1 23408788 0018 LC ARF2 GGA1 11124697,11124697,12221117 0004,0018,0018 LC GGA1 GGA1 PDB_5CN2,PDB_5CN1 0114,0114 LC UBI4 GGA1 15039776,15039776 0004,0018 LC SSA1 GGA1 16429126 0676 HT SSA2 GGA1 16429126 0676 HT ARF1 GGA1 11124697,11124697 0018,0004 LC SSB1 GGA1 19536198,16429126 0676,0676 HT ARF2 GGA1 11124697,11124697 0004,0018 LC CHC1 GGA1 11689690,11408593 0096,0004 LC HSP104 GGA1 19536198 0676 HT PSA1 GGA1 16429126 0676 HT MON2 GGA1 18418388 0004 LC GGA1 HSP42 19536198 0676 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q12329 Q06336 HSP42 GGA1 0.126 19536198 Q06336 P0CG53 GGA1 UBB 0.309 20150893 Q06336 P0CG63 GGA1 UBI4 0.454 15039776 Q06336 P11484 GGA1 SSB1 0.236 16429126,19536198 Q06336 P19146 GGA1 ARF2 0.454 11124697 Q06336 P0CG48 GGA1 UBC 0.309 17494868 Q06336 P10591 GGA1 SSA1 0.126 16429126 Q06336 P10592 GGA1 SSA2 0.126 16429126 Q06336 P11076 GGA1 ARF1 0.623 11124697,20601958 Q06336 P13134 GGA1 KEX2 0.309 23408788 Q06336 P22137 GGA1 CHC1 0.21 11408593 Q06336 P31539 GGA1 HSP104 0.126 19536198 Q06336 P41940 GGA1 PSA1 0.126 16429126 Q06336 P48563 GGA1 MON2 0.21 18418388 Q07807 Q06336 PUF3 GGA1 0.126 23409723