PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus GPH1 RAD30 11805837 biogrid,mint,intact,dip exp UBC7 RAD30 14690591 intact exp RAD30 THI20 11805837 dip exp SSB1 RAD30 19536198 intact exp HLJ1 RAD30 18467557 biogrid,i2d,mint,intact exp UBI4 RAD30 21483899,20837403 biogrid exp SNF1 RAD30 16554755 biogrid,i2d,mint,intact exp ATP1 RAD30 11805837 dip exp LPD1 RAD30 11805837 dip exp ATP2 RAD30 11805837 dip exp GIM4 RAD30 19536198 intact exp HSP78 RAD30 19536198 intact exp PSA1 RAD30 11805837 dip exp GLK1 RAD30 11805837 dip exp ARG3 RAD30 11805837 dip exp XRN1 RAD30 11805837 dip exp LSM12 RAD30 16554755 biogrid,i2d,mint,intact exp CTK3 RAD30 i2d exp NAM7 RAD30 18087042 biogrid exp SSA3 RAD30 19536198 intact exp URA2 RAD30 11805837 dip exp SNU13 RAD30 16554755 biogrid,i2d,mint,intact exp PFD1 RAD30 19536198 intact exp SNF4 RAD30 16554755 biogrid,i2d,mint,intact exp MRH4 RAD30 18467557 biogrid,i2d,mint,intact exp SSB2 RAD30 23332755,19536198 biogrid,intact exp SSA1 RAD30 19536198 intact exp TVP23 RAD30 18467557 biogrid,i2d,mint,intact exp YDJ1 RAD30 11805837 dip exp RAD30 GAL83 16554755 biogrid,i2d,mint,intact exp RAD30 RBS1 18467557, 23023127 biogrid,i2d,mint,intact exp, pred POL30 RAD30 23506842,19264809,22308326,20967232,20837403,17251197,18494853,19053247,11545742, 23023127 biogrid,intact,dip exp, pred REV1 RAD30 17875922,23550131, 23023127 biogrid exp, pred RAD6 RAD30 23023127 pred RAD18 RAD30 23023127 pred REV3 RAD30 23023127 pred RAD52 RAD30 23023127 pred REV7 RAD30 23023127 pred MMS2 RAD30 23023127 pred POL31 RAD30 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P06738 Q04049 - 11805837 - X 2 P39990 Q04049 affinity chromatography technology 16554755 physical association X 2 Q04049 P12689 two hybrid 23550131 direct interaction X 2 Q04049 Q04739 affinity chromatography technology 16554755 physical association X 2 Q04049 P12689 affinity chromatography technology 17875922 physical association X 2 Q04049 P12689 affinity chromatography technology 17875922 physical association X 2 Q04049 P53166 protein complementation assay 18467557 direct interaction X 2 Q04049 Q9M7Q7 two hybrid 18494853 direct interaction X 2 P06782 Q04049 affinity chromatography technology 16554755 physical association X 2 P0CG63 Q04049 affinity chromatography technology 23749301 physical association X 2 P0CG63 Q04049 affinity chromatography technology 23793018 physical association X 2 P0CG63 Q04049 affinity chromatography technology 17874115 physical association X 2 P0CG63 Q04049 two hybrid 20837403 direct interaction X 2 P0CG63 Q04049 pull down 21483899 direct interaction X 2 P06738 Q04049 affinity chromatography technology 11805837 physical association X 2 P38962 Q04049 protein complementation assay 18467557 direct interaction X 2 P38828 Q04049 affinity chromatography technology 16554755 physical association X 2 Q04049 P12904 affinity chromatography technology 16554755 physical association X 2 Q04049 Q05672 protein complementation assay 18467557 direct interaction X 2 Q04049 P48353 protein complementation assay 18467557 direct interaction X 2 P15873 Q04049 two hybrid 11545742 direct interaction X 2 P15873 Q04049 pull down 23506842 direct interaction X 2 P15873 Q04049 two hybrid 17251197 direct interaction X 2 P15873 Q04049 pull down 19053247 direct interaction X 2 P15873 Q04049 two hybrid 19264809 direct interaction X 2 P15873 Q04049 two hybrid 18494853 direct interaction X 2 P15873 Q04049 two hybrid 20837403 direct interaction X 2 P15873 Q04049 two hybrid 22308326 direct interaction X 2 P40150 Q04049 biochemical 23332755 association X 2 Q9ZW35 Q04049 two hybrid 18494853 direct interaction X 2 P22147 Q04049 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04049 P05150 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04049 P07259 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04049 anti tag coimmunoprecipitation 11805837 - C 11 P06738 Q04049 anti tag coimmunoprecipitation 11805837 physical association X 2 P41940 Q04049 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04049 P07251 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04049 P00830 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04049 P17709 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04049 P25491 anti tag coimmunoprecipitation 11805837 physical association X 2 P15873 Q04049 solid phase assay 20967232 direct interaction X 2 P15873 Q04049 two hybrid 20967232 direct interaction X 2 P15873 Q04049 surface plasmon resonance 20967232 direct interaction X 2 P15873 Q04049 solid phase assay 20967232 direct interaction X 2 Q08224 Q04049 anti tag coimmunoprecipitation 11805837 physical association X 2 P09624 Q04049 anti tag coimmunoprecipitation 11805837 physical association X 2 P11484 Q04049 tandem affinity purification 19536198 association X 2 P39990 Q04049 tandem affinity purification 16554755 physical association X 2 P39990 Q04049 tandem affinity purification 16554755 physical association X 2 P46988 Q04049 tandem affinity purification 19536198 association X 2 Q04049 Q04739 tandem affinity purification 16554755 physical association X 2 Q04049 Q04739 tandem affinity purification 16554755 physical association X 2 Q04049 P53166 dihydrofolate reductase reconstruction 18467557 physical association X 2 Q04049 Q9M7Q7 two hybrid 18494853 physical association X 2 Q04049 P09435 tandem affinity purification 19536198 association X 2 Q04049 P40005 tandem affinity purification 19536198 association X 2 P10591 Q04049 tandem affinity purification 19536198 association X 2 Q04049 inferred by author 16554755 association C 7 P06782 Q04049 tandem affinity purification 16554755 physical association X 2 P06782 Q04049 tandem affinity purification 16554755 physical association X 2 P06738 Q04049 anti tag coimmunoprecipitation 11805837 physical association X 2 Q02159 Q04049 two hybrid array 14690591 physical association X 2 P38962 Q04049 dihydrofolate reductase reconstruction 18467557 physical association X 2 P38828 Q04049 tandem affinity purification 16554755 physical association X 2 P38828 Q04049 tandem affinity purification 16554755 physical association X 2 Q04049 P12904 tandem affinity purification 16554755 physical association X 2 Q04049 P12904 tandem affinity purification 16554755 physical association X 2 Q04049 P48353 dihydrofolate reductase reconstruction 18467557 physical association X 2 Q04049 Q05672 dihydrofolate reductase reconstruction 18467557 physical association X 2 Q04049 P33416 tandem affinity purification 19536198 association X 2 P15873 Q04049 molecular sieving 11545742 physical association X 2 P15873 Q04049 two hybrid 11545742 physical association X 2 P15873 Q04049 two hybrid 18494853 physical association X 2 P40150 Q04049 tandem affinity purification 19536198 association X 2 Q9ZW35 Q04049 two hybrid 18494853 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality UBI4 RAD30 20837403 0018 LC REV1 RAD30 23550131 0018 LC POL30 RAD30 17251197,11545742,19264809,20967232,22308326,20837403,20967232,20967232,18494853,11545742 0018,0018,0018,0018,0018,0018,0892,0107,0018,0071 LC TVP23 RAD30 18467557,18467557 0111,0090 HT SSB2 RAD30 23332755 0401 LC HLJ1 RAD30 18467557,18467557 0111,0090 HT MRH4 RAD30 18467557,18467557 0111,0090 HT UBC7 RAD30 14690591 0397 LC RAD30 RAD30 21076032,20333640,11545743,17991862 0114,0114,0114,0114 LC RAD30 RBS1 18467557,18467557 0111,0090 HT ATP2 RAD30 11805837 0007 HT ARG3 RAD30 11805837 0007 HT GPH1 RAD30 11805837,11805837 0004,0007 HT SNF1 RAD30 16554755,16554755 0676,0004 HT ATP1 RAD30 11805837 0007 HT URA2 RAD30 11805837 0007 HT SSA3 RAD30 19536198 0676 HT LPD1 RAD30 11805837 0007 HT UBI4 RAD30 21483899 0096 LC SSA1 RAD30 19536198 0676 HT SSB1 RAD30 19536198 0676 HT REV1 RAD30 17875922 0004 LC SNF4 RAD30 16554755,16554755,16554755 0363,0676,0004 HT POL30 RAD30 23506842,19053247 0096,0096 LC GLK1 RAD30 11805837 0007 HT XRN1 RAD30 11805837 0007 HT YDJ1 RAD30 11805837 0007 HT HSP78 RAD30 19536198 0676 HT LSM12 RAD30 16554755,16554755 0676,0004 HT SNU13 RAD30 16554755,16554755 0676,0004 HT GIM4 RAD30 19536198 0676 HT SSB2 RAD30 19536198,23332755 0676,0401 HT,LC PSA1 RAD30 11805837 0007 HT PFD1 RAD30 19536198 0676 HT RAD30 GAL83 16554755,16554755 0676,0004 HT RAD30 THI20 11805837 0007 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q04049 P10591 RAD30 SSA1 0.126 19536198 Q04049 P09624 RAD30 LPD1 0.126 11805837 Q04049 P05150 RAD30 ARG3 0.126 11805837 Q04049 P07251 RAD30 ATP1 0.126 11805837 Q04049 P12904 RAD30 SNF4 0.416 16554755 Q04049 P06782 RAD30 SNF1 0.236 16554755 Q04049 P0CG63 RAD30 UBI4 0.523 20837403,21483899 Q04049 P39990 RAD30 SNU13 0.236 16554755 Q04049 P48353 RAD30 HLJ1 0.286 18467557 Q04049 P40150 RAD30 SSB2 0.236 23332755,19536198 Q04049 P15873 RAD30 POL30 0.941 20837403,18494853,19053247,22308326,11545742,23506842 Q04049 P30771 RAD30 NAM7 0.126 18087042 Q04049 P38828 RAD30 LSM12 0.332 16554755 Q04049 P38962 RAD30 TVP23 0.126 18467557 Q04049 P33416 RAD30 HSP78 0.126 19536198 Q04049 P17709 RAD30 GLK1 0.126 11805837 Q04049 P07259 RAD30 URA2 0.126 11805837 Q04049 P06738 RAD30 GPH1 0.236 11805837 Q04049 P00830 RAD30 ATP2 0.126 11805837 Q04739 Q04049 GAL83 RAD30 0.236 16554755 Q04049 P12689 RAD30 REV1 0.569 17875922,23550131 Q04049 P09435 RAD30 SSA3 0.126 19536198 Q04049 P11484 RAD30 SSB1 0.126 19536198 Q04049 Q02159 RAD30 UBC7 0.126 14690591 Q04049 P40005 RAD30 GIM4 0.126 19536198 Q04049 P22147 RAD30 XRN1 0.126 11805837 Q04049 P25491 RAD30 YDJ1 0.126 11805837 Q04049 P53166 RAD30 MRH4 0.286 18467557 Q04049 P41940 RAD30 PSA1 0.126 11805837 Q04049 P46988 RAD30 PFD1 0.126 19536198 Q05672 Q04049 RBS1 RAD30 0.286 18467557 Q08224 Q04049 THI20 RAD30 0.126 11805837 Q9ZW35 Q04049 PCNA2 RAD30 0.523 18494853 Q9M7Q7 Q04049 PCNA RAD30 0.523 18494853