PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HSP82 TOM1 19536198,15766533 biogrid,intact exp RFC1 TOM1 i2d exp RSM10 TOM1 i2d exp RPS31 TOM1 i2d exp UBP15 TOM1 i2d exp JJJ1 TOM1 19536198 intact exp RPL40B TOM1 16554755 biogrid,i2d exp HHF1, HHF2 TOM1 19578373 biogrid exp TOM1 HSP42 19536198 intact exp HSP78 TOM1 19536198 intact exp TEF4 TOM1 i2d exp Uncharacterized protein YJR056C TOM1 i2d exp PEA2 TOM1 i2d exp PRS2 TOM1 i2d exp RPG1 TOM1 i2d exp CMD1 TOM1 i2d exp PRS3 TOM1 16429126 intact exp CDC6 TOM1 23129771 biogrid exp SBP1 TOM1 23222640 biogrid exp APA1 TOM1 16429126 intact exp PFD1 TOM1 19536198 intact exp NGG1 TOM1 9753545 biogrid,i2d,dip exp TOM1 LAG2 16554755 biogrid,i2d,mint,intact exp RAD53 TOM1 19578373 biogrid exp UBP6 TOM1 i2d exp YDJ1 TOM1 19536198 intact exp TOM1 DIA2 22933573 biogrid exp ACC1 TOM1 16429126 intact exp ZUO1 TOM1 19536198,16554755 biogrid,i2d,mint,intact exp SSB1 TOM1 19536198 i2d,intact exp HSC82 TOM1 19536198,15766533,16554755 biogrid,i2d,mint,intact exp SSA1 TOM1 19536198 i2d,intact exp CRM1 TOM1 i2d exp TOM1 YRA1 20810649,17922018 biogrid exp TOM1 HCR1 i2d exp TOM1 PUF3 23409723,26493364 biogrid exp SSB2 TOM1 19536198 intact exp MLC1 TOM1 16554755 biogrid,i2d,mint,intact exp SSE1 TOM1 19536198 intact exp UBI4 TOM1 15039776,16554755 biogrid,i2d,mint,intact exp SSA2 TOM1 19536198 i2d,intact exp SPT5 TOM1 12556496 biogrid exp SNU13 TOM1 i2d exp EGD2 TOM1 i2d exp RPL40A TOM1 i2d exp MAE1 TOM1 16429126 biogrid,intact exp SIS1 TOM1 19536198 intact exp YEF3 TOM1 16554755 biogrid,i2d,mint,intact exp SSZ1 TOM1 19536198,16554755 biogrid,i2d,mint,intact exp TOM1 HIM1 i2d exp HSP104 TOM1 19536198 intact exp ESS1 TOM1 11805837 biogrid,mint,intact,dip exp AAP1 TOM1 16429126 intact exp STP1 TOM1 16554755 biogrid,i2d,mint,intact exp HXK2 TOM1 i2d exp TOM1 CMR1 22199229 biogrid exp HHT1, HHT2 TOM1 22199229 biogrid exp PAC10 TOM1 19536198 intact exp FMP48 TOM1 20489023, 23023127 biogrid,mint,intact exp, pred MYO2 TOM1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred SPA2 TOM1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred KRR1 TOM1 11027267, 23023127 biogrid,intact,dip exp, pred MYO4 TOM1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred NAB2 TOM1 19840948, 23023127 biogrid exp, pred UBI4 TOM1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q03280 - 11805837 - C 17 Q03280 P15108 - 15766533 - X 2 Q03280 P32494 - 9753545 - X 2 Q03280 P38788 - 15766533 - X 2 Q03280 P11484 - 15766533 - X 2 Q03280 P10592 - 15766533 - X 2 Q03280 - 15766533 - X 2 Q03280 P27692 affinity chromatography technology 12556496 physical association X 2 Q03280 P09119 affinity chromatography technology 23129771 physical association X 2 Q03280 P09119 affinity chromatography technology 23129771 physical association X 2 Q03280 P25586 two hybrid 11027267 direct interaction X 2 Q03280 P02829 affinity chromatography technology 15766533 physical association X 2 Q03280 P32492 affinity chromatography technology 16554755 physical association X 2 Q03280 P0CH08 affinity chromatography technology 16554755 physical association X 2 Q03280 P23201 affinity chromatography technology 16554755 physical association X 2 Q03280 P16521 affinity chromatography technology 16554755 physical association X 2 Q03280 Q00947 affinity chromatography technology 16554755 physical association X 2 Q03280 P36013 affinity chromatography technology 16429126 physical association X 2 Q03280 P22216 affinity chromatography technology 19578373 physical association X 2 Q03280 P22696 affinity chromatography technology 11805837 physical association X 2 P53233 Q03280 affinity chromatography technology 20489023 physical association X 2 P0CG63 Q03280 affinity chromatography technology 15039776 physical association X 2 P0CG63 Q03280 affinity chromatography technology 23749301 physical association X 2 P0CG63 Q03280 biochemical 23583075 association X 2 P0CG63 Q03280 affinity chromatography technology 17644757 physical association X 2 P0CG63 Q03280 affinity chromatography technology 23793018 physical association X 2 P0CG63 Q03280 affinity chromatography technology 12872131 physical association X 2 P0CG63 Q03280 affinity chromatography technology 21427232 physical association X 2 P0CG63 Q03280 affinity chromatography technology 14557538 physical association X 2 Q08496 Q03280 affinity chromatography technology 22933573 physical association X 2 Q03280 P32494 affinity chromatography technology 9753545 physical association X 2 Q03280 P32494 affinity chromatography technology 9753545 physical association X 2 Q03280 Q12159 affinity chromatography technology 20810649 physical association X 2 Q03280 P53141 affinity chromatography technology 16554755 physical association X 2 Q03280 P32527 affinity chromatography technology 16554755 physical association X 2 Q03280 P38788 affinity chromatography technology 16554755 physical association X 2 Q03280 P15108 affinity chromatography technology 16554755 physical association X 2 Q03280 P19524 affinity chromatography technology 16554755 physical association X 2 Q03280 Q92325 affinity chromatography technology 16554755 physical association X 2 Q03280 Q12159 affinity chromatography technology 17922018 physical association X 2 Q03280 P02309 enzymatic study 19578373 direct interaction X 2 Q03280 P02309 enzymatic study 19578373 direct interaction X 2 Q03280 P61830 affinity chromatography technology 22199229 physical association X 2 Q03280 P61830 affinity chromatography technology 22199229 physical association X 2 Q03280 Q12510 affinity chromatography technology 22199229 physical association X 2 Q03280 anti tag coimmunoprecipitation 11805837 - C 25 Q03280 P25586 two hybrid 11027267 physical association X 2 Q03280 anti tag coimmunoprecipitation 11805837 - C 17 Q03280 P32494 coimmunoprecipitation 9753545 physical association X 2 Q03280 anti tag coimmunoprecipitation 11805837 physical association X 2 Q03280 inferred by author 16429126 physical association C 29 Q03280 anti tag coimmunoprecipitation 20489023 association C 30 Q03280 inferred by author 16429126 physical association C 38 Q03280 inferred by author 16429126 physical association C 51 Q03280 inferred by author 16429126 physical association C 39 Q03280 inferred by author 16429126 physical association C 8 Q03280 tandem affinity purification 16429126 association C 64 Q03280 P25586 two hybrid 11027267 physical association X 2 Q03280 P32492 tandem affinity purification 16554755 physical association X 2 Q03280 P23201 tandem affinity purification 16554755 physical association X 2 Q03280 P23201 tandem affinity purification 16554755 physical association X 2 Q03280 P23201 tandem affinity purification 16554755 physical association X 2 Q03280 P16521 tandem affinity purification 16554755 physical association X 2 Q03280 P16521 tandem affinity purification 16554755 physical association X 2 Q03280 P23201 tandem affinity purification 16554755 physical association X 2 Q03280 P23201 tandem affinity purification 16554755 physical association X 2 Q03280 P32492 tandem affinity purification 16554755 physical association X 2 Q03280 Q00947 tandem affinity purification 16554755 physical association X 2 Q03280 P25294 tandem affinity purification 19536198 association X 2 Q03280 P25491 tandem affinity purification 19536198 association X 2 Q03280 P53863 tandem affinity purification 19536198 association X 2 Q03280 P02829 tandem affinity purification 19536198 association X 2 Q03280 P33416 tandem affinity purification 19536198 association X 2 Q03280 P31539 tandem affinity purification 19536198 association X 2 Q03280 inferred by author 16429126 physical association C 21 Q03280 tandem affinity purification 16429126 association C 56 Q03280 inferred by author 16429126 physical association C 38 Q03280 anti tag coimmunoprecipitation 11805837 association C 17 P32589 Q03280 tandem affinity purification 19536198 association X 2 P0CG63 Q03280 tandem affinity purification 16554755 physical association X 2 P0CG63 Q03280 tandem affinity purification 16554755 physical association X 2 P0CG63 Q03280 tandem affinity purification 16554755 physical association X 2 P10591 Q03280 tandem affinity purification 19536198 association X 2 Q03280 P15108 affinity chromatography technology 15766533 physical association X 2 Q03280 Q92325 inferred by author 16554755 association X 2 Q03280 P19524 tandem affinity purification 16554755 physical association X 2 Q03280 P19524 tandem affinity purification 16554755 physical association X 2 Q03280 P15108 tandem affinity purification 16554755 physical association X 2 Q03280 P19524 tandem affinity purification 16554755 physical association X 2 Q03280 P19524 tandem affinity purification 16554755 physical association X 2 Q03280 P19524 tandem affinity purification 16554755 physical association X 2 Q03280 P19524 tandem affinity purification 16554755 physical association X 2 Q03280 P32527 tandem affinity purification 16554755 physical association X 2 Q03280 P38788 tandem affinity purification 16554755 physical association X 2 Q03280 P15108 tandem affinity purification 16554755 physical association X 2 Q03280 P32527 tandem affinity purification 16554755 physical association X 2 Q03280 P53141 tandem affinity purification 16554755 physical association X 2 Q03280 P19524 tandem affinity purification 16554755 physical association X 2 Q03280 Q92325 tandem affinity purification 16554755 physical association X 2 Q03280 P32527 tandem affinity purification 19536198 association X 2 Q03280 P11484 tandem affinity purification 19536198 association X 2 Q03280 P38788 tandem affinity purification 19536198 association X 2 Q03280 P10592 tandem affinity purification 19536198 association X 2 Q03280 P40150 tandem affinity purification 19536198 association X 2 Q03280 P48363 tandem affinity purification 19536198 association X 2 Q03280 P46988 tandem affinity purification 19536198 association X 2 Q03280 P15108 tandem affinity purification 19536198 association X 2 Q03280 Q12329 tandem affinity purification 19536198 association X 2 Q03280 mass spectrometry studies of complexes 11805837 - C 18 Q03280 P32494 coimmunoprecipitation 9753545 - X 2

PPI - HINT Gene A Gene B PMID Method Quality HHF1|HHF2 TOM1 19578373 0415 LC KRR1 TOM1 11027267 0018 LC NGG1 TOM1 9753545,9753545 0004,0019 LC RPN10 TOM1 26205498 0415 LC TOM1 TOM1 26205498 0415 LC HSP82 TOM1 19536198,15766533 0676,0004 HT,LC CDC6 TOM1 23129771 0004 LC UBI4 TOM1 16554755,15039776,19252184,14557538 0676,0004,0004,0004 HT,LC RPL40A TOM1 16554755 0004 HT RPL40B TOM1 16554755 0004 HT SSA1 TOM1 19536198 0676 HT SSA2 TOM1 19536198,15766533 0676,0004 HT,LC SSB1 TOM1 19536198,15766533 0676,0004 HT,LC HSC82 TOM1 19536198,15766533,16554755,16554755 0676,0004,0676,0004 HT,LC YEF3 TOM1 16554755,16554755 0676,0004 HT APA1 TOM1 16429126 0676 HT MYO2 TOM1 16554755,16554755 0676,0004 HT RAD53 TOM1 19578373 0004 LC ESS1 TOM1 11805837,11805837 0004,0007 HT SPA2 TOM1 16554755,16554755 0676,0004 HT SIS1 TOM1 19536198 0676 HT YDJ1 TOM1 19536198 0676 HT SPT5 TOM1 12556496 0004 LC HSP104 TOM1 19536198 0676 HT MYO4 TOM1 16554755,16554755 0676,0004 HT NGG1 TOM1 9753545,9753545 0004,0019 LC NAB2 TOM1 19840948 0004 LC ZUO1 TOM1 19536198,16554755,16554755 0676,0676,0004 HT SSE1 TOM1 19536198 0676 HT HSP78 TOM1 19536198 0676 HT MAE1 TOM1 16429126,16429126 0676,0004 HT AAP1 TOM1 16429126 0363 HT PRS3 TOM1 16429126 0363 HT SSZ1 TOM1 19536198,15766533,16554755,16554755 0676,0004,0676,0004 HT,LC RSP5 TOM1 26508657 0004 LC SSB2 TOM1 19536198 0676 HT PFD1 TOM1 19536198 0676 HT PAC10 TOM1 19536198 0676 HT MLC1 TOM1 16554755,16554755 0676,0004 HT FMP48 TOM1 20489023,20489023 0007,0004 HT JJJ1 TOM1 19536198 0676 HT HHT1|HHT2 TOM1 22199229 0004 HT STP1 TOM1 16554755,16554755 0676,0004 HT ACC1 TOM1 16429126 0363 HT TOM1 DIA2 22933573 0004 LC TOM1 YRA1 17922018,20810649 0004,0004 LC TOM1 HSP42 19536198 0676 HT TOM1 CMR1 22199229 0004 HT TOM1 LAG2 16554755,16554755,16554755 0363,0676,0004 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q03280 P23201 TOM1 SPA2 0.332 16554755 Q03280 P25294 TOM1 SIS1 0.126 19536198 Q03280 P25491 TOM1 YDJ1 0.126 19536198 Q03280 P10080 TOM1 SBP1 0.126 23222640 Q03280 P11484 TOM1 SSB1 0.126 19536198 Q03280 P15108 TOM1 HSC82 0.416 16554755,15766533,19536198 Q03280 P0CG63 TOM1 UBI4 0.309 16554755,15039776 Q07807 Q03280 PUF3 TOM1 0.236 26493364,23409723 Q03280 P32527 TOM1 ZUO1 0.416 16554755,19536198 Q03280 P16521 TOM1 YEF3 0.236 16554755 Q03280 P38788 TOM1 SSZ1 0.332 16554755,19536198 Q03280 P37898 TOM1 AAP1 0.126 16429126 Q03280 P31539 TOM1 HSP104 0.126 19536198 Q03280 P38689 TOM1 PRS3 0.126 16429126 Q03280 P32492 TOM1 MYO4 0.332 16554755 Q03280 P32494 TOM1 NGG1 0.236 9753545 Q03280 P32505 TOM1 NAB2 0.126 19840948 Q03280 P39940 TOM1 RSP5 0.126 26508657 Q03280 P33416 TOM1 HSP78 0.126 19536198 Q03280 P36013 TOM1 MAE1 0.126 16429126 Q03280 P46988 TOM1 PFD1 0.126 19536198 Q12510 Q03280 Q12510 TOM1 0.126 22199229 Q03280 P48363 TOM1 PAC10 0.126 19536198 Q03280 P16550 TOM1 APA1 0.126 16429126 Q03280 Q00947 TOM1 STP1 0.236 16554755 Q03280 Q00955 TOM1 ACC1 0.126 16429126 Q03280 P19524 TOM1 MYO2 0.332 16554755 Q03280 P02309 TOM1 HHF2 0.309 19578373 Q03280 P02829 TOM1 HSP82 0.236 15766533,19536198 Q03280 P09119 TOM1 CDC6 0.376 23129771 Q03280 P0CH08 TOM1 RPL40A 0.126 16554755 Q03280 P0CH09 TOM1 RPL40B 0.126 16554755 Q03280 P10591 TOM1 SSA1 0.126 19536198 Q03280 P10592 TOM1 SSA2 0.126 19536198 Q03280 P22696 TOM1 ESS1 0.332 11805837 Q03280 P25586 TOM1 KRR1 0.309 11027267 Q03280 P32589 TOM1 SSE1 0.126 19536198 Q03280 P38886 TOM1 RPN10 0.309 26205498 Q03280 P40150 TOM1 SSB2 0.126 19536198 Q03280 P53141 TOM1 MLC1 0.236 16554755 Q03280 P53233 TOM1 FMP48 0.332 20489023 Q03280 P53863 TOM1 JJJ1 0.126 19536198 Q03280 Q03280 TOM1 TOM1 0.332 26205498 Q08496 Q03280 DIA2 TOM1 0.21 22933573 Q12159 Q03280 YRA1 TOM1 0.309 20810649,17922018 Q12329 Q03280 HSP42 TOM1 0.126 19536198 Q92325 Q03280 LAG2 TOM1 0.332 16554755