PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SPP41 IFH1 22875988 biogrid exp SPP41 NST1 22875988 biogrid exp SUP35 SPP41 i2d exp NMD2 SPP41 9032286 dip exp SIF2 SPP41 i2d exp SLA1 SPP41 11743162 mint exp SPT10 SPP41 25228766 biogrid exp FPR1 SPP41 9315655 i2d,dip exp HSP78 SPP41 19536198 intact exp SPP41 SIZ1 23712011 biogrid exp RAP1 SPP41 i2d exp SPP41 UBC9 23712011 biogrid exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P20081 P38904 - 9315655 - X 2 P0CG63 P38904 affinity chromatography technology 23749301 physical association X 2 P38904 P39520 two hybrid 22875988 direct interaction X 2 P38904 Q04195 affinity chromatography technology 23712011 physical association X 2 P38904 P50623 affinity chromatography technology 23712011 physical association X 2 P38904 Q12306 affinity chromatography technology 23935535 physical association X 2 P38904 Q12306 affinity chromatography technology 15326169 physical association X 2 P38904 Q12306 affinity chromatography technology 15166219 physical association X 2 P38904 Q12306 affinity chromatography technology 15542864 physical association X 2 P35208 P38904 affinity chromatography technology 25228766 physical association X 2 P38904 P53935 two hybrid 22875988 direct interaction X 2 P20081 P38904 two hybrid 9315655 physical association X 2 P38798 P38904 two hybrid 9032286 physical association X 2 P38904 P33416 tandem affinity purification 19536198 association X 2 P20081 P38904 two hybrid 9315655 - X 2 P38904 P11938 two hybrid - - X 2

PPI - HINT Gene A Gene B PMID Method Quality FPR1 SPP41 9315655 0018 LC NMD2 SPP41 9032286 0018 LC SPP41 IFH1 22875988 0018 HT SPP41 NST1 22875988 0018 HT HSP78 SPP41 19536198 0676 HT SPT10 SPP41 25228766 0004 HT SPP41 UBC9 23712011 0004 LC SPP41 SIZ1 23712011 0004 LC SPP41 SMT3 15326169,15166219,15542864 0004,0004,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P38904 P35208 SPP41 SPT10 0.126 25228766 P38904 P38798 SPP41 NMD2 0.033 9032286 P38904 P33416 SPP41 HSP78 0.126 19536198 P50623 P38904 UBC9 SPP41 0.126 23712011 P38904 P20081 SPP41 FPR1 0.033 9315655 Q04195 P38904 SIZ1 SPP41 0.126 23712011