PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HSP104 SEH1 19536198 intact exp GDH1 SEH1 11805837 dip exp MIS1 SEH1 16429126 intact exp AIM4 SEH1 10684247 intact exp IML1 SEH1 21454883,25073740,18046405 biogrid,intact exp RPO21 SEH1 23703787 biogrid exp IPP1 SEH1 11805837 dip exp SSZ1 SEH1 19536198 intact exp MLP2 SEH1 24500206,10617624,24152732 biogrid exp SEH1 SWA2 19536198 intact exp CDC19 SEH1 18046405 biogrid exp ENO1 SEH1 11805837 dip exp ACO1 SEH1 11805837 dip exp FPR2 SEH1 21179020 intact exp SEH1 ARO8 11805837 dip exp HXK1 SEH1 11805837 dip exp GPP1 SEH1 11805837 dip exp RTS1 SEH1 11283351 i2d,mint,intact,dip exp MET6 SEH1 11805837 dip exp ENO2 SEH1 18046405 biogrid exp TUB3 SEH1 11805837 dip exp SAH1 SEH1 11805837 dip exp CYS4 SEH1 16429126 intact exp GND1 SEH1 11805837 dip exp SEH1 DIA2 11805837 biogrid,mint,intact,dip exp SSB2 SEH1 23332755 biogrid exp AAR2 SEH1 16429126 intact exp SEH1 MLP1 24152732 biogrid exp HSC82 SEH1 11805837 dip exp BMH1 SEH1 11805837 dip exp OST1 SEH1 11805826,16429126 biogrid,mint,intact,dip exp ILV2 SEH1 11805837 dip exp GAL10 SEH1 11805837 dip exp APE3 SEH1 11805837 biogrid,mint,intact,dip exp SPB4 SEH1 21825077 biogrid exp SEA4 SEH1 21454883,25073740,18046405 biogrid,intact exp SEH1 GCN5 21734642 biogrid,intact exp SWE1 SEH1 16319894 biogrid exp SEH1 NAF1 14690591 intact exp NPR2 SEH1 21454883,25073740 biogrid,intact exp DSN1 SEH1 21107429 biogrid exp URA2 SEH1 18046405 biogrid exp TDH3 SEH1 18046405 biogrid exp SPO7 SEH1 i2d exp NPR3 SEH1 21454883,25073740 biogrid,intact exp SNF6 SEH1 16429126 intact exp SHM2 SEH1 11805837 dip exp ADH1 SEH1 18046405 biogrid exp SEH1 PUF3 23409723 biogrid exp SEH1 ADE13 11805837 biogrid,intact,dip exp CCT4 SEH1 19536198 intact exp, ortho SEH1 SEH1 22940862 biogrid exp, ortho SEH1 MEX67 17922018,18046452,16554755, 23023127 biogrid,intact exp, ortho, pred SEH1 SEC13 16429126,8565072,15741174,11805837,11805826,10747086,21454883,18046405, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred SEH1 KAP95 17897934, 23023127 biogrid exp, ortho, pred SEH1 MTC5 21454883,25073740,18046405,11805837, 23023127 biogrid,mint,intact,dip exp, ortho, pred NIC96 SEH1 18046405, 23023127 biogrid exp, ortho, pred NUP188 SEH1 18046405, 23023127 biogrid exp, pred KIN2 SEH1 20489023, 23023127 biogrid,mint,intact exp, pred NUP159 SEH1 18046405, 23023127 biogrid exp, pred NUP192 SEH1 18046405, 23023127 biogrid exp, pred NUP170 SEH1 18046405, 23023127 biogrid exp, pred SAC3 SEH1 17922018, 23023127 biogrid exp, pred POM152 SEH1 18046405, 23023127 biogrid exp, pred SMB1 SEH1 16429126, 23023127 biogrid,intact exp, pred MTR2 SEH1 18046452, 23023127 biogrid,intact exp, pred NSP1 SEH1 18046405, 23023127 biogrid exp, pred SEH1 RTC1 21454883,25073740,18046405, 23023127 biogrid,intact exp, pred SEH1 GLE1 10684247, 23023127 intact exp, pred MCK1 SEH1 20489023, 23023127 biogrid,mint,intact exp, pred SEH1 NUP53 18046405, 23023127 biogrid exp, pred NUP133 SEH1 25139911,15741174,18046405, 23023127 biogrid exp, pred NUP157 SEH1 15741174,18046405, 23023127 biogrid exp, pred NUP84 SEH1 16429126,8565072,18046452,15741174,11805837,10747086,21454883,19822444,10617624,12543930,18046405, 23023127 biogrid,i2d,intact,dip exp, pred NUP85 SEH1 21784248,19576787,18046452,15741174,18160040,11805837,10747086,21454883,19111661,18974315,10617624,18046405, 23023127 biogrid,i2d,mint,intact,dip exp, pred NUP145 SEH1 9305650,16429126,18046452,15741174,16554755,11805837,10747086,21454883,20512149,10617624,18046405, 23023127 biogrid,i2d,mint,intact,dip exp, pred SEC27 SEH1 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred NAB2 SEH1 19840948, 23023127 biogrid exp, pred TEF1, TEF2 SEH1 18046405, 23023127 biogrid exp, pred NUP82 SEH1 18046405, 23023127 biogrid exp, pred BRR2 SEH1 16429126, 23023127 biogrid,intact exp, pred NUP120 SEH1 10747086,21454883,16429126,8565072,15741174,10617624,18046405, 23023127 biogrid,intact,dip exp, pred SEH1 NUP116 17418788,10684247,12543930, 23023127 biogrid,intact exp, pred VPH1 SEH1 ortho PMI40 SEH1 ortho UBC9 SEH1 ortho SEH1 UPF0586 protein YNL092W ortho CCT7 SEH1 ortho CCT3 SEH1 ortho RFA2 SEH1 ortho SEH1 VPS30 ortho CCT5 SEH1 ortho BNA6 SEH1 ortho SEH1 SSU72 ortho RFA1 SEH1 ortho RNA1 SEH1 ortho ARP1 SEH1 ortho GLE2 SEH1 23023127 ortho, pred NUP2 SEH1 23023127 pred SEH1 CIA1 23023127 pred KAP104 SEH1 23023127 pred SEH1 NUP100 23023127 pred DBP5 SEH1 23023127 pred CDC31 SEH1 23023127 pred SEH1 CBC2 23023127 pred YRB1 SEH1 23023127 pred GSP2 SEH1 23023127 pred SEH1 NUP49 23023127 pred GPA1 SEH1 23023127 pred NUP42 SEH1 23023127 pred GSP1 SEH1 23023127 pred YRB2 SEH1 23023127 pred SRM1 SEH1 23023127 pred NUP1 SEH1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P53011 - 11805826 - C 8 P53011 - 15044803 - C 6 P53011 - 11805837 - C 12 P53011 - 11805837 - C 33 P53011 - 11805826 - C 8 P53011 P38903 - 11283351 - X 2 P53011 - 11805837 - C 6 P53011 - 11805837 - C 6 P53011 - 11805826 - C 8 P53011 - 11805837 - X 2 P34232 P53011 affinity chromatography technology 18046452 physical association X 2 P38181 P53011 affinity chromatography technology 18046405 physical association X 2 P40368 P53011 affinity chromatography technology 18046405 physical association X 2 P53011 P36161 affinity chromatography technology 25139911 physical association X 2 P53011 P36161 affinity chromatography technology 15741174 physical association X 2 P53011 P36161 affinity chromatography technology 15741174 physical association X 2 P53011 Q99257 affinity chromatography technology 17922018 physical association X 2 P53011 Q99257 affinity chromatography technology 18046452 physical association X 2 P53011 P21965 affinity chromatography technology 20489023 physical association X 2 P53011 P36161 affinity chromatography technology 18046405 physical association X 2 P53011 P40477 affinity chromatography technology 18046405 physical association X 2 P53011 P36161 affinity chromatography technology 18046405 physical association X 2 P53011 P00549 affinity chromatography technology 18046405 physical association X 2 P0CG63 P53011 affinity chromatography technology 23749301 physical association X 2 P0CG63 P53011 affinity chromatography technology 22213798 physical association X 2 P38742 P53011 affinity chromatography technology 21454883 physical association X 2 P38742 P53011 affinity chromatography technology 21454883 physical association X 2 Q02630 P53011 affinity chromatography technology 12543930 physical association X 2 Q02630 P53011 biochemical 10684247 association X 2 P39685 P53011 affinity chromatography technology 18046405 physical association X 2 P00359 P53011 affinity chromatography technology 18046405 physical association X 2 P47170 P53011 affinity chromatography technology 21454883 physical association X 2 P47170 P53011 affinity chromatography technology 21454883 physical association X 2 P47170 P53011 affinity chromatography technology 18046405 physical association X 2 P41811 P53011 affinity chromatography technology 11805826 physical association X 2 P40568 P53011 affinity chromatography technology 21107429 physical association X 2 P40018 P53011 affinity chromatography technology 16429126 physical association X 2 P13186 P53011 affinity chromatography technology 20489023 physical association X 2 Q08281 P53011 affinity chromatography technology 21454883 physical association X 2 Q08281 P53011 affinity chromatography technology 21454883 physical association X 2 Q08281 P53011 affinity chromatography technology 18046405 physical association X 2 P46674 P53011 affinity chromatography technology 17922018 physical association X 2 P32639 P53011 affinity chromatography technology 16429126 physical association X 2 Q03330 P53011 affinity chromatography technology 21734642 physical association X 2 Q05911 P53011 affinity chromatography technology 11805837 physical association X 2 P25808 P53011 affinity chromatography technology 21825077 physical association X 2 P38164 P53011 affinity chromatography technology 21454883 physical association X 2 P38164 P53011 affinity chromatography technology 21454883 physical association X 2 P38164 P53011 affinity chromatography technology 18046405 physical association X 2 P49687 P53011 affinity chromatography technology 9305650 physical association X 2 P35729 P53011 affinity chromatography technology 10747086 physical association X 2 P49687 P53011 affinity chromatography technology 10747086 physical association X 2 P35729 P53011 affinity chromatography technology 10617624 physical association X 2 P49687 P53011 affinity chromatography technology 10617624 physical association X 2 P49687 P53011 affinity chromatography technology 16554755 physical association X 2 P49687 P53011 affinity chromatography technology 16429126 physical association X 2 P35729 P53011 affinity chromatography technology 16429126 physical association X 2 P35729 P53011 affinity chromatography technology 15741174 physical association X 2 P49687 P53011 affinity chromatography technology 15741174 physical association X 2 P49687 P53011 affinity chromatography technology 15741174 physical association X 2 P35729 P53011 affinity chromatography technology 15741174 physical association X 2 P49687 P53011 affinity chromatography technology 17200106 physical association X 2 P35729 P53011 affinity chromatography technology 17200106 physical association X 2 P49687 P53011 pull down 18046452 direct interaction X 2 P49687 P53011 affinity chromatography technology 20512149 physical association X 2 P35729 P53011 affinity chromatography technology 21454883 physical association X 2 P49687 P53011 affinity chromatography technology 21454883 physical association X 2 P35729 P53011 affinity chromatography technology 18046405 physical association X 2 P49687 P53011 affinity chromatography technology 18046405 physical association X 2 P35729 P53011 affinity chromatography technology 18046405 physical association X 2 P49687 P53011 affinity chromatography technology 18046405 physical association X 2 P49687 P53011 affinity chromatography technology 11805837 physical association X 2 P47054 P53011 affinity chromatography technology 18046405 physical association X 2 P34077 P53011 affinity chromatography technology 18046405 physical association X 2 Q03790 P53011 affinity chromatography technology 18046405 physical association X 2 P52891 P53011 affinity chromatography technology 10747086 physical association X 2 P52891 P53011 affinity chromatography technology 10747086 physical association X 2 P52891 P53011 affinity chromatography technology 10617624 physical association X 2 P52891 P53011 biochemical 12543930 association X 2 P52891 P53011 affinity chromatography technology 16429126 physical association X 2 P52891 P53011 affinity chromatography technology 15741174 physical association X 2 P52891 P53011 affinity chromatography technology 15741174 physical association X 2 P52891 P53011 pull down 15741174 direct interaction X 2 P52891 P53011 affinity chromatography technology 17200106 physical association X 2 P52891 P53011 affinity chromatography technology 18046452 physical association X 2 P52891 P53011 affinity chromatography technology 19822444 physical association X 2 P52891 P53011 affinity chromatography technology 21454883 physical association X 2 P52891 P53011 affinity chromatography technology 18046405 physical association X 2 P52891 P53011 affinity chromatography technology 18046405 physical association X 2 P52891 P53011 affinity chromatography technology 11805837 physical association X 2 P53011 P53011 affinity chromatography technology 22940862 physical association X 2 P53011 P40457 affinity chromatography technology 10617624 physical association X 2 P53011 P40457 affinity chromatography technology 24500206 physical association X 2 P53011 P32944 enzymatic study 16319894 direct interaction X 2 P53011 P40064 pull down 15741174 direct interaction X 2 P53011 Q03897 affinity chromatography technology 21454883 physical association X 2 P53011 Q03897 affinity chromatography technology 21454883 physical association X 2 P53011 P40064 affinity chromatography technology 18046405 physical association X 2 P53011 P14907 affinity chromatography technology 18046405 physical association X 2 P53011 Q03897 affinity chromatography technology 18046405 physical association X 2 P53011 P02994 affinity chromatography technology 18046405 physical association X 2 P53011 P00925 affinity chromatography technology 18046405 physical association X 2 P53011 P00330 affinity chromatography technology 18046405 physical association X 2 P53011 Q03897 affinity chromatography technology 11805837 physical association X 2 Q04491 P53011 affinity chromatography technology 10747086 physical association X 2 Q04491 P53011 affinity chromatography technology 16429126 physical association X 2 Q04491 P53011 affinity chromatography technology 15741174 physical association X 2 Q04491 P53011 affinity chromatography technology 17200106 physical association X 2 Q04491 P53011 affinity chromatography technology 21454883 physical association X 2 Q04491 P53011 affinity chromatography technology 18046405 physical association X 2 Q04491 P53011 affinity chromatography technology 11805826 physical association X 2 Q04491 P53011 affinity chromatography technology 11805837 physical association X 2 P07259 P53011 affinity chromatography technology 18046405 physical association X 2 P46673 P53011 affinity chromatography technology 10747086 physical association X 2 P46673 P53011 affinity chromatography technology 10617624 physical association X 2 P46673 P53011 affinity chromatography technology 15741174 physical association X 2 P46673 P53011 affinity chromatography technology 15741174 physical association X 2 P46673 P53011 affinity chromatography technology 17200106 physical association X 2 P46673 P53011 pull down 18046452 direct interaction X 2 P46673 P53011 pull down 19111661 direct interaction X 2 P46673 P53011 biochemical 19111661 association X 2 P46673 P53011 x-ray crystallography 19111661 association X 2 P46673 P53011 x-ray crystallography 18974315 association X 2 P46673 P53011 pull down 18974315 direct interaction X 2 P46673 P53011 biochemical 18160040 association X 2 P46673 P53011 affinity chromatography technology 21454883 physical association X 2 P46673 P53011 affinity chromatography technology 18046405 physical association X 2 P46673 P53011 pull down 18046405 direct interaction X 2 P46673 P53011 pull down 18046405 direct interaction X 2 P46673 P53011 affinity chromatography technology 18046405 physical association X 2 P46673 P53011 affinity chromatography technology 11805837 physical association X 2 P46673 P53011 affinity chromatography technology 11805837 physical association X 2 Q08496 P53011 affinity chromatography technology 11805837 physical association X 2 P41543 P53011 affinity chromatography technology 11805826 physical association X 2 Q06142 P53011 pull down 17897934 direct interaction X 2 P40150 P53011 biochemical 23332755 association X 2 P52593 P53011 affinity chromatography technology 18046405 physical association X 2 P37302 P53011 affinity chromatography technology 11805837 physical association X 2 P39923 P53011 affinity chromatography technology 21454883 physical association X 2 P39923 P53011 affinity chromatography technology 21454883 physical association X 2 P53011 tandem affinity purification 11805826 - C 8 P53011 anti tag coimmunoprecipitation 11805837 - C 12 P53011 anti tag coimmunoprecipitation 11805837 - C 7 P53011 electron microscopy 20512149 physical association C 5 P53011 pull down 20512149 physical association C 5 P53011 molecular sieving 19576787 physical association C 5 P53011 pull down 19576787 physical association C 5 P53011 tandem affinity purification 11805826 - C 8 P53011 anti tag coimmunoprecipitation 11805837 - C 8 P53011 inferred by author 11805826 physical association C 16 P53011 tandem affinity purification 19503077 physical association C 7 P53011 transmission electron microscopy 19503077 physical association C 7 P53011 light scattering 19503077 physical association C 7 P53011 tandem affinity purification 19503077 physical association C 7 P53011 P38903 two hybrid pooling approach 11283351 physical association X 2 P53011 P19414 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 P37291 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P07342 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P15108 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P07262 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P41811 P53011 tandem affinity purification 11805826 physical association X 2 P09734 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P05694 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 Q05911 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P49687 P53011 pull down 20512149 physical association X 2 P49687 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P49687 P53011 affinity chromatography technology 10747086 physical association X 2 P35729 P53011 pull down 19576787 physical association X 2 P35729 P53011 affinity chromatography technology 8565072 physical association X 2 P35729 P53011 affinity chromatography technology 10747086 physical association X 2 P53011 inferred by author 11805826 physical association C 15 P53011 anti tag coimmunoprecipitation 11805837 - C 6 P53011 tandem affinity purification 11805826 - C 8 P53011 anti tag coimmunoprecipitation 11805837 - C 34 P53011 anti tag coimmunoprecipitation 11805837 - C 23 P53011 anti tag coimmunoprecipitation 11805837 - C 35 P53011 inferred by author 11805826 physical association C 9 P53011 anti tag coimmunoprecipitation 11805837 - C 45 P52891 P53011 affinity chromatography technology 8565072 physical association X 2 P52891 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P52891 P53011 affinity chromatography technology 10747086 physical association X 2 P39954 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P53090 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 P04806 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 P00817 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 Q03897 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04491 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04491 P53011 tandem affinity purification 11805826 physical association X 2 Q04491 P53011 affinity chromatography technology 8565072 physical association X 2 Q04491 P53011 affinity chromatography technology 10747086 physical association X 2 P00924 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P04397 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P46673 P53011 affinity chromatography technology 8565072 direct interaction X 2 P46673 P53011 tandem affinity purification 19503077 direct interaction X 2 P46673 P53011 affinity chromatography technology 10747086 direct interaction X 2 P46673 P53011 anti tag coimmunoprecipitation 11805837 direct interaction X 2 P46673 P53011 molecular sieving 19576787 direct interaction X 2 P46673 P53011 anti tag coimmunoprecipitation 11805837 direct interaction X 2 P38720 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P41543 P53011 tandem affinity purification 11805826 physical association X 2 P29311 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P37302 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 tandem affinity purification 21734642 association C 157 P53011 tandem affinity purification 16429126 association C 10 P53011 inferred by author 16429126 physical association C 16 P53011 tandem affinity purification 16429126 association C 11 P53011 inferred by author 16429126 physical association C 52 P53011 electron microscopy 10684247 physical association C 26 P53011 tandem affinity purification 21179020 association C 47 P53011 tandem affinity purification 16429126 association C 47 P53011 tandem affinity purification 11805826 association C 9 P53011 tandem affinity purification 16429126 association C 44 P53011 chromatography technology 10684247 physical association C 57 P53011 affinity chromatography technology 25073740 association C 9 P53011 inferred by author 16429126 physical association C 70 P53011 inferred by author 16429126 physical association C 54 P53011 anti tag coimmunoprecipitation 20489023 association C 35 P53011 affinity chromatography technology 25073740 association C 36 P53011 tandem affinity purification 16429126 association C 7 P53011 P38903 two hybrid fragment pooling approach 11283351 physical association X 2 P53011 Q06677 tandem affinity purification 19536198 association X 2 P53011 P31539 tandem affinity purification 19536198 association X 2 Q02630 P53011 pull down 17418788 direct interaction X 2 P38164 P53011 affinity chromatography technology 25073740 physical association X 2 P38164 P53011 affinity chromatography technology 25073740 physical association X 2 P49687 P53011 tandem affinity purification 16554755 physical association X 2 P49687 P53011 tandem affinity purification 16554755 physical association X 2 P49687 P53011 tandem affinity purification 16554755 physical association X 2 P53011 anti tag coimmunoprecipitation 11805837 association C 6 P53011 affinity chromatography technology 25073740 association C 7 P53011 tandem affinity purification 18046452 association C 8 P53011 anti tag coimmunoprecipitation 11805837 association C 6 P53011 affinity chromatography technology 25073740 association C 24 P53011 affinity chromatography technology 25073740 association C 27 P53011 affinity chromatography technology 25073740 association C 5 P53011 anti tag coimmunoprecipitation 20489023 association C 35 P53011 affinity chromatography technology 25073740 association C 32 P53011 inferred by author 16554755 association C 6 P53011 tandem affinity purification 16429126 association C 6 P53011 affinity chromatography technology 25073740 association C 10 P53011 inferred by author 16429126 physical association C 38 P53011 tandem affinity purification 16429126 association C 30 P53011 affinity chromatography technology 25073740 association C 18 P53011 affinity chromatography technology 25073740 association C 24 P53011 anti tag coimmunoprecipitation 11805837 association C 12 P53011 tandem affinity purification 11805826 association C 9 P53011 tandem affinity purification 16429126 association C 12 P53011 tandem affinity purification 16429126 association C 23 P53011 tandem affinity purification 11805826 association C 9 P53011 anti tag coimmunoprecipitation 11805837 association C 33 P53011 tandem affinity purification 16429126 association C 14 P53011 affinity chromatography technology 25073740 association C 8 P53011 affinity chromatography technology 25073740 association C 8 P53011 affinity chromatography technology 25073740 association C 8 P53011 cross-linking study 25073740 physical association C 8 P53011 cosedimentation through density gradient 25073740 physical association C 8 P53011 tandem affinity purification 18046452 association C 3 P46673 P53011 molecular sieving 18160040 physical association X 2 P46673 P53011 molecular sieving 18160040 physical association X 2 P46673 P53011 two hybrid 21784248 physical association X 2 P53919 P53011 two hybrid array 14690591 physical association X 2 P39078 P53011 tandem affinity purification 19536198 association X 2 P38788 P53011 tandem affinity purification 19536198 association X 2 P37302 P53011 anti tag coimmunoprecipitation 11805837 physical association X 2 P53011 confirmational text mining - - C 6 P53011 mass spectrometry studies of complexes 11805826 - C 21 P53011 mass spectrometry studies of complexes 11805837 - C 35 P53011 P38903 two hybrid 11283351 - X 2 P53011 mass spectrometry studies of complexes 11805837 - C 8 P53011 mass spectrometry studies of complexes 11805837 - C 8 P53011 mass spectrometry studies of complexes 11805826 - C 12 P53011 mass spectrometry studies of complexes 11805837 - C 13 P53011 mass spectrometry studies of complexes 11805826 - C 18 P53011 mass spectrometry studies of complexes 11805837 - C 7 P18410 P53011 interaction detection method 9822591 - X 2

PPI - HINT Gene A Gene B PMID Method Quality SWE1 SEH1 16319894 0415 LC NUP120 SEH1 27194810 1247 LC AIM4 SEH1 10684247 0091 LC RTS1 SEH1 11283351,11283351,11283351 0018,0399,0398 HT SSB2 SEH1 23332755 0401 LC NUP85 SEH1 19111661,18160040,27194810,19111661,21784248,19576787,18160040,18974315,18974315,19111661 0114,0071,0397,0401,0018,0071,0401,0114,0096,0096 LC IML1 SEH1 25073740,25073740,25073740 0004,0030,0029 LC NUP84 SEH1 12543930 0401 LC SEH1 NAF1 14690591 0397 LC SEH1 NUP116 10684247 0401 LC SEH1 GLE1 10684247 0040 LC ADH1 SEH1 18046405 0004 LC TDH3 SEH1 18046405 0004 LC CDC19 SEH1 18046405 0004 LC IPP1 SEH1 11805837 0007 HT ENO1 SEH1 11805837 0007 HT ENO2 SEH1 18046405 0004 LC TEF1|TEF2 SEH1 18046405 0004 LC RPO21 SEH1 23703787 0004 LC GAL10 SEH1 11805837 0007 HT HXK1 SEH1 11805837 0007 HT MET6 SEH1 11805837 0007 HT URA2 SEH1 18046405 0004 LC GDH1 SEH1 11805837 0007 HT ILV2 SEH1 11805837 0007 HT MIS1 SEH1 16429126 0676 HT TUB3 SEH1 11805837 0007 HT UBI4 SEH1 22213798 0004 LC KIN2 SEH1 20489023,20489023 0007,0004 HT NSP1 SEH1 18046405 0004 LC HSC82 SEH1 11805837 0007 HT SNF6 SEH1 16429126 0676 HT ACO1 SEH1 11805837 0007 HT MCK1 SEH1 20489023,20489023 0007,0004 HT SPB4 SEH1 21825077 0004 LC BMH1 SEH1 11805837 0007 HT HSP104 SEH1 19536198 0676 HT AAR2 SEH1 16429126 0363 HT FPR2 SEH1 21179020 0676 HT NAB2 SEH1 19840948 0004 LC CYS4 SEH1 16429126 0363 HT BRR2 SEH1 16429126,16429126 0676,0004 HT NIC96 SEH1 18046405 0004 LC MTR2 SEH1 18046452,18046452 0676,0004 LC NUP120 SEH1 21454883,10747086,15741174,16429126,10617624,19576787,8565072,17200106,16429126,18046405 0004,0004,0004,0004,0004,0096,0004,0004,0676,0004 LC,HT NUP133 SEH1 25139911,18046405,15741174 0004,0004,0004 LC SHM2 SEH1 11805837 0007 HT APE3 SEH1 11805837,11805837 0004,0007 HT SEA4 SEH1 25073740,21454883,18046405 0004,0004,0004 LC NUP170 SEH1 18046405 0004 LC GND1 SEH1 11805837 0007 HT NPR3 SEH1 25073740,21454883 0004,0004 LC SSZ1 SEH1 19536198 0676 HT CCT4 SEH1 19536198 0676 HT POM152 SEH1 18046405 0004 LC NPR2 SEH1 25073740,21454883 0004,0004 LC SAH1 SEH1 11805837 0007 HT SMB1 SEH1 16429126,16429126 0676,0004 HT NUP157 SEH1 15741174,18046405 0096,0004 LC SSB2 SEH1 23332755 0401 LC NUP82 SEH1 18046405 0004 LC MLP2 SEH1 24500206,24152732,10617624 0004,0004,0004 LC NUP159 SEH1 18046405 0004 LC DSN1 SEH1 21107429 0004 HT GPP1 SEH1 11805837 0007 HT OST1 SEH1 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT SEC27 SEH1 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT NUP85 SEH1 21454883,19111661,8565072,18160040,17200106,18046405,10747086,18046452,11805837,19111661,15741174,18046405,10617624,18160040,11805837,18974315,19503077,18974315,19111661 0004,0114,0004,0071,0004,0004,0004,0096,0004,0401,0004,0096,0004,0401,0007,0114,0676,0096,0096 LC,HT SAC3 SEH1 17922018 0004 LC NUP192 SEH1 18046405 0004 LC IML1 SEH1 25073740,25073740,25073740,21454883,18046405 0004,0030,0029,0004,0004 LC NUP145 SEH1 11805837,16554755,10747086,15741174,20512149,16429126,10617624,11805837,9305650,20512149,17200106,18046452,16554755,21454883,16429126,18046405 0004,0676,0004,0004,0004,0676,0004,0007,0004,0096,0004,0096,0004,0004,0004,0004 HT,LC NUP188 SEH1 18046405 0004 LC NUP84 SEH1 11805837,18046452,10747086,21454883,15741174,16429126,10617624,12543930,8565072,15741174,18046452,19822444,17200106,16429126,11805837,18046405 0004,0676,0004,0004,0004,0676,0004,0401,0004,0096,0004,0004,0004,0004,0007,0004 HT,LC SEH1 SEH1 22940862 0004 HT SEH1 ARO8 11805837 0007 HT SEH1 MLP1 24152732 0004 LC SEH1 NUP116 10684247,12543930,17418788 0401,0004,0096 LC SEH1 GCN5 21734642,21734642 0676,0004 LC SEH1 NUP53 18046405 0004 LC SEH1 MTC5 11805837,25073740,11805837,21454883,18046405 0004,0004,0007,0004,0004 HT,LC SEH1 SEC13 11805837,10747086,21454883,15741174,16429126,11805826,11805837,8565072,11805826,17200106,11805826,16429126,18046405 0004,0004,0004,0004,0676,0004,0007,0004,0676,0004,0007,0004,0004 HT,LC SEH1 ADE13 11805837,11805837 0004,0007 HT SEH1 KAP95 17897934 0096 LC SEH1 SWA2 19536198 0676 HT SEH1 RTC1 25073740,21454883,18046405 0004,0004,0004 LC SEH1 DIA2 11805837,11805837 0004,0007 HT SEH1 MEX67 18046452,17922018,18046452,16554755 0676,0004,0004,0363 LC,HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q12315 P53011 GLE1 SEH1 0.126 10684247 P53011 P09734 SEH1 TUB3 0.126 11805837 P53011 P00924 SEH1 ENO1 0.126 11805837 P53011 P09440 SEH1 MIS1 0.126 16429126 P53011 P04806 SEH1 HXK1 0.126 11805837 P53011 P05694 SEH1 MET6 0.126 11805837 P53011 P07262 SEH1 GDH1 0.126 11805837 Q08281 P53011 RTC1 SEH1 0.523 25073740,21454883,18046405 Q02630 P53011 NUP116 SEH1 0.286 17418788,12543930 Q03330 P53011 GCN5 SEH1 0.236 21734642 P53011 P35729 SEH1 NUP120 0.623 10747086,27194810,19576787,16429126,21454883,8565072,18046405 P53011 P38164 SEH1 SEA4 0.583 25073740,21454883,18046405 P53011 P47170 SEH1 IML1 0.636 25073740,21454883,18046405 P53011 P49687 SEH1 NUP145 0.757 10747086,16429126,21454883,20512149,16554755,11805837,18046405 P53011 P40064 SEH1 NUP157 0.396 18046405,15741174 Q04491 P53011 SEC13 SEH1 0.671 11805826,10747086,16429126,21454883,11805837,8565072,18046405 P53011 P52891 SEH1 NUP84 0.808 18046452,16429126,11805837,8565072,18046405,19822444,15741174,21454883,10747086 P53011 P46673 SEH1 NUP85 0.986 18974315,27194810,21784248,19111661,11805837,8565072,19503077,18046405,18160040,21454883,10747086,19576787 P53011 P37291 SEH1 SHM2 0.126 11805837 P53011 P37302 SEH1 APE3 0.126 11805837 P53011 P25808 SEH1 SPB4 0.126 21825077 Q8WUM0 P53011 NUP133 SEH1 0.126 27194810 P53011 P31539 SEH1 HSP104 0.309 27373154,19536198 P53011 P38305 SEH1 AIM4 0.126 10684247 P53011 P32357 SEH1 AAR2 0.126 16429126 P53011 P32472 SEH1 FPR2 0.126 21179020 P53011 P38720 SEH1 GND1 0.126 11805837 P53011 P38788 SEH1 SSZ1 0.126 19536198 P53011 P32505 SEH1 NAB2 0.126 19840948 P53011 P38903 SEH1 RTS1 0.236 11283351 P53011 P32582 SEH1 CYS4 0.126 16429126 P53011 P32639 SEH1 BRR2 0.126 16429126 P53011 P32944 SEH1 SWE1 0.183 16319894 P53011 P39954 SEH1 SAH1 0.126 11805837 P53011 P40018 SEH1 SMB1 0.126 16429126 P53011 P40150 SEH1 SSB2 0.126 23332755 P53011 P40457 SEH1 MLP2 0.126 24152732 P53011 P40568 SEH1 DSN1 0.126 21107429 P53011 P46674 SEH1 SAC3 0.126 17922018 P53011 P41277 SEH1 RHR2 0.126 11805837 P53011 P41543 SEH1 OST1 0.286 11805826,16429126 P53011 P41811 SEH1 SEC27 0.286 11805826,16429126 P53011 P18888 SEH1 SNF6 0.126 16429126 P53011 P19414 SEH1 ACO1 0.126 11805837 Q02455 P53011 MLP1 SEH1 0.126 24152732 Q06677 P53011 SWA2 SEH1 0.126 19536198 Q03790 P53011 NUP53 SEH1 0.126 18046405 Q03897 P53011 MTC5 SEH1 0.597 11805837,25073740,18046405,21454883 Q07807 P53011 PUF3 SEH1 0.126 23409723 P53011 P21965 SEH1 MCK1 0.286 20489023 Q08496 P53011 DIA2 SEH1 0.236 11805837 P53919 P53011 NAF1 SEH1 0.126 14690591 P53011 P07259 SEH1 URA2 0.126 18046405 P53011 P04397 SEH1 GAL10 0.126 11805837 P53011 P00359 SEH1 TDH3 0.126 18046405 P53011 P00330 SEH1 ADH1 0.126 18046405 P53011 P04050 SEH1 RPO21 0.376 23703787 P53011 P00549 SEH1 CDC19 0.126 18046405 P53011 P02994 SEH1 TEF2 0.126 18046405 P53011 P00817 SEH1 IPP1 0.126 11805837 P53011 P00925 SEH1 ENO2 0.126 18046405 P53090 P53011 ARO8 SEH1 0.126 11805837 P53011 P13186 SEH1 KIN2 0.332 20489023 P53011 P07342 SEH1 ILV2 0.126 11805837 P53011 P29311 SEH1 BMH1 0.126 11805837 P53011 P14907 SEH1 NSP1 0.126 18046405 P53011 P15108 SEH1 HSC82 0.126 11805837 P53011 P39078 SEH1 CCT4 0.126 19536198 P53011 P36161 SEH1 NUP133 0.126 18046405 P53011 P34077 SEH1 NIC96 0.126 18046405 P53011 P34232 SEH1 MTR2 0.21 18046452 P53011 P38742 SEH1 NPR3 0.454 25073740,21454883 P53011 P38181 SEH1 NUP170 0.126 18046405 P53011 P40477 SEH1 NUP159 0.126 18046405 P53011 P39923 SEH1 NPR2 0.454 25073740,21454883 P53011 P39685 SEH1 POM152 0.126 18046405 P53011 P40368 SEH1 NUP82 0.126 18046405 P53011 P52593 SEH1 NUP188 0.126 18046405 P53011 P47054 SEH1 NUP192 0.126 18046405 Q05911 P53011 ADE13 SEH1 0.21 11805837 Q06142 P53011 KAP95 SEH1 0.309 17897934 Q99257 P53011 MEX67 SEH1 0.396 16554755,18046452,17922018