PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus AMA1 HSP42 19536198 intact exp CDC27 AMA1 23816140 biogrid exp SSE1 AMA1 19536198 intact exp CLB1 AMA1 21118994 biogrid exp SSB2 AMA1 19536198 intact exp AMA1 UBC7 14690591 intact exp SSA2 AMA1 19536198 intact exp SIS1 AMA1 19536198 intact exp SSA1 AMA1 19536198 intact exp ECM10 AMA1 19536198 intact exp CCT3 AMA1 19536198 intact exp BMH2 AMA1 i2d exp CCT8 AMA1 19536198 intact exp MER1 AMA1 17634282, 23023127 biogrid exp, pred BUD14 AMA1 19841731, 23023127 biogrid,mint,intact exp, pred CDC16 AMA1 11114178, 23023127 biogrid,intact,dip exp, pred CDC20 AMA1 23816140,21118994, 23023127 biogrid exp, pred PDS1 AMA1 23023127 pred AMA1 SWM1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P50082 P16523 two hybrid 17634282 direct interaction X 2 P50082 P24868 affinity chromatography technology 21118994 physical association X 2 P09798 P50082 affinity chromatography technology 11114178 physical association X 2 P26309 P50082 enzymatic study 23816140 direct interaction X 2 P26309 P50082 affinity chromatography technology 21118994 physical association X 2 P50082 P38042 affinity chromatography technology 23816140 physical association X 2 P50082 P40316 enzymatic study 15797379 direct interaction X 2 P50082 P27637 two hybrid 19841731 direct interaction X 2 P09798 P50082 coimmunoprecipitation 11114178 physical association X 2 P10592 P50082 tandem affinity purification 19536198 association X 2 P50082 P25294 tandem affinity purification 19536198 association X 2 P50082 P39987 tandem affinity purification 19536198 association X 2 P50082 P47079 tandem affinity purification 19536198 association X 2 P50082 Q12329 tandem affinity purification 19536198 association X 2 P09798 P50082 anti tag coimmunoprecipitation 11114178 physical association X 2 P32589 P50082 tandem affinity purification 19536198 association X 2 P50082 P27637 two hybrid pooling approach 19841731 physical association X 2 P39077 P50082 tandem affinity purification 19536198 association X 2 Q02159 P50082 two hybrid array 14690591 physical association X 2 P40150 P50082 tandem affinity purification 19536198 association X 2 P10591 P50082 tandem affinity purification 19536198 association X 2

PPI - HINT Gene A Gene B PMID Method Quality CDC16 AMA1 11114178,11114178,11114178 0007,0004,0019 LC MER1 AMA1 17634282 0018 HT CDC20 AMA1 23816140 0415 LC BUD14 AMA1 19841731,19841731 0398,0018 HT PDS1 AMA1 15797379 0415 LC AMA1 UBC7 14690591 0397 LC CDC16 AMA1 11114178,11114178,11114178 0007,0004,0019 LC SSA1 AMA1 19536198 0676 HT SSA2 AMA1 19536198 0676 HT CLB1 AMA1 21118994 0004 LC SIS1 AMA1 19536198 0676 HT CDC20 AMA1 21118994 0004 LC SSE1 AMA1 19536198 0676 HT CDC27 AMA1 23816140 0004 LC CCT3 AMA1 19536198 0676 HT ECM10 AMA1 19536198 0676 HT SSB2 AMA1 19536198 0676 HT CCT8 AMA1 19536198 0676 HT AMA1 HSP42 19536198 0676 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q12329 P50082 HSP42 AMA1 0.126 19536198 P50082 P25294 AMA1 SIS1 0.126 19536198 P50082 P09798 AMA1 CDC16 0.033 11114178 P50082 P10591 AMA1 SSA1 0.126 19536198 P50082 P26309 AMA1 CDC20 0.454 23816140,21118994 P50082 P32589 AMA1 SSE1 0.126 19536198 P50082 P39077 AMA1 CCT3 0.126 19536198 P50082 P40150 AMA1 SSB2 0.126 19536198 P50082 P47079 AMA1 CCT8 0.126 19536198 P50082 P10592 AMA1 SSA2 0.126 19536198 P50082 P16523 AMA1 MER1 0.183 17634282 P50082 P24868 AMA1 CLB1 0.21 21118994 P50082 P27637 AMA1 BUD14 0.376 19841731 P50082 P38042 AMA1 CDC27 0.21 23816140 P50082 P39987 AMA1 ECM10 0.126 19536198 Q02159 P50082 UBC7 AMA1 0.126 14690591