PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HSE1 ALG8 19841731 mint,intact exp HSE1 LAP3 11743162 biogrid,i2d,mint,intact,dip exp RPL40A HSE1 12055639 dip exp HSE1 ATG17 23904270 biogrid exp RRP7 HSE1 19841731 biogrid,mint,intact exp HSE1 FOX2 19841731 biogrid,mint,intact exp PHO4 HSE1 19841731 biogrid,mint,intact exp BPT1 HSE1 19841731 mint,intact exp EAP1 HSE1 11743162 mint exp HSE1 SKI7 19841731,11743162 biogrid,i2d,mint,intact,dip exp MTH1 HSE1 19841731 biogrid,mint,intact exp BCH2 HSE1 11743162 mint exp MUM2 HSE1 22875988 biogrid exp HSE1 POP2 19841731 biogrid,mint,intact exp HSE1 CDC73 11743162 mint exp HSE1 MPS1 11743162 mint exp HSE1 END3 22875988 biogrid exp RPO31 HSE1 11743162 mint exp HSE1 RUP1 17079730 biogrid exp SSA1 HSE1 22940862 biogrid exp HSE1 VHR2 11743162 mint exp BRN1 HSE1 16554755 biogrid,i2d,mint,intact exp HSE1 UBP2 17079730 biogrid exp TY1B-A HSE1 11743162 biogrid,i2d,mint,intact exp HSE1 GDS1 19841731 biogrid,mint,intact exp HSE1 FIR1 11743162 mint exp HSE1 APP1 19841731 biogrid,mint,intact exp HSE1 YBP2 19841731 mint,intact exp HSE1 TUS1 11743162 mint exp HSE1 PEF1 11743162 mint exp HSE1 RGC1 11743162 biogrid,i2d,mint,intact,dip exp ADE3 HSE1 19841731 mint,intact exp HSE1 STE20 11743162 mint exp FIG1 HSE1 19841731 mint,intact exp PAF1 HSE1 19841731,11743162 biogrid,i2d,mint,intact,dip exp HSE1 Uncharacterized vacuolar membrane protein YJR054W 19841731 mint,intact exp MRS3 HSE1 11743162 mint exp HSE1 AIM21 19841731 mint,intact exp PBI2 HSE1 11283351 i2d,mint,intact,dip exp HSE1 HER1 19841731 biogrid,mint,intact exp UBI4 HSE1 12750381,12055639 biogrid exp HSE1 NDC80 19841731 biogrid,mint,intact exp TYE7 HSE1 22875988 biogrid exp HSE1 YAP6 11283351 i2d,mint,intact,dip exp GDA1 HSE1 19841731 mint,intact exp HSE1 UBP7 19841731,11743162,17079730 biogrid,i2d,mint,intact,dip exp HSE1 MET31 19841731 biogrid,mint,intact exp HSE1 BUL1 11743162 biogrid,i2d,mint,intact,dip exp HSE1 YTA12 11743162,19841731 biogrid,mint,intact exp DOA1 HSE1 19841731,11743162,24607902,18508771 biogrid,i2d,mint,intact,dip exp HSE1 BRE4 11743162 mint exp HSE1 INN1 11743162 mint exp HSE1 SUE1 11743162 mint exp HSE1 HMO1 11743162 biogrid,i2d,mint,intact,dip exp HSE1 MAK21 i2d exp HSE1 SSB2 23332755 biogrid exp Putative glutamine--fructose-6-phosphate aminotransferase [isomerizing], GFAT HSE1 19841731 biogrid exp HSE1 GCV2 19841731 mint,intact exp UBP13 HSE1 19841731 biogrid,mint,intact exp ECM29 HSE1 21321079 biogrid exp HSE1 RRI2 21289098 biogrid exp HSE1 ACF2 19841731 biogrid,mint,intact exp SSB1 HSE1 22940862 biogrid exp ARE1 HSE1 19841731 biogrid,mint,intact exp HSE1 BSP1 11743162, 23023127 biogrid,i2d,mint,intact,dip exp, pred ARG81 HSE1 19841731, 23023127 biogrid,mint,intact exp, pred AIM3 HSE1 19841731, 23023127 biogrid,mint,intact exp, pred HSE1 VPS27 15086794,16429126,22615397,18467557,11283351,16554755,20826334,20305637,11805826,14581452,10688190,12055639,17543868, 23023127 biogrid,i2d,mint,intact,dip exp, pred HSE1 ZAP1 19841731, 23023127 mint,intact exp, pred HSE1 MVP1 19841731, 23023127 mint,intact exp, pred HSE1 Putative uncharacterized protein YNR005C 10688190, 23023127 i2d,mint,intact,dip exp, pred HSE1 PRK1 19841731, 23023127 mint,intact exp, pred HSE1 Uncharacterized protein YEL023C 16554755, 23023127 biogrid,i2d,mint,intact exp, pred HSE1 HSE1 11805826,18467557, 23023127 biogrid,i2d,mint,intact exp, pred HSE1 SHO1 11743162, 23023127 biogrid,i2d,mint,intact,dip exp, pred HSE1 POC4 19841731, 23023127 biogrid,mint,intact exp, pred HSE1 BNI1 19841731, 23023127 mint,intact exp, pred HSE1 ACC1 19841731, 23023127 biogrid,mint,intact exp, pred CYC8 HSE1 19841731, 23023127 biogrid,mint,intact exp, pred SPS1 HSE1 19841731, 23023127 mint,intact exp, pred SLA1 HSE1 19841731, 23023127 biogrid,mint,intact exp, pred HSE1 MYO5 11743162, 23023127 biogrid,i2d,mint,intact,dip exp, pred HSE1 HUA1 11283351,17079730, 23023127 biogrid,i2d,mint,intact,dip exp, pred HSE1 LAS17 11743162,19841731, 23023127 biogrid,mint,intact exp, pred STP22 HSE1 15086794,19841731,11743162, 23023127 biogrid,i2d,mint,intact,dip exp, pred HSE1 RVS167 23023127 i2d exp, pred SBP1 HSE1 19841731, 23023127 biogrid,mint,intact exp, pred HSE1 MDS3 19841731, 23023127 mint,intact exp, pred ACB1 HSE1 19841731, 23023127 biogrid,mint,intact exp, pred HSE1 RSP5 15086794,17079730, 23023127 biogrid exp, pred HSE1 LSB1 23023127 pred CDC24 HSE1 23023127 pred HSE1 ENT2 23023127 pred HSE1 GGA1 23023127 pred YSC84 HSE1 23023127 pred HSE1 SNF7 23023127 pred ATG12 HSE1 23023127 pred HSE1 ENT5 23023127 pred HSE1 PEX13 23023127 pred ATG8 HSE1 23023127 pred PBI2 HSE1 23023127 pred HSE1 ENT1 23023127 pred HSE1 ENT3 23023127 pred HSE1 BZZ1 23023127 pred RHB1 HSE1 23023127 pred CDC25 HSE1 23023127 pred HSE1 VPS20 23023127 pred MYO3 HSE1 23023127 pred HSE1 VPS60 23023127 pred HSE1 UBI4 23023127 pred HSE1 LSB3 23023127 pred FUS1 HSE1 23023127 pred HSE1 ZIM17 23023127 pred HSE1 IST1 23023127 pred HSE1 CYK3 23023127 pred HSE1 BBC1 23023127 pred HSE1 BRO1 23023127 pred HSE1 GGA2 23023127 pred Putative truncated guanine nucleotide exchange factor YLL017W HSE1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O13527 P38753 - 11743162 - X 2 Q03973 P38753 - 11743162 - X 2 P25604 P38753 - 11489916,11743162 - X 2 P25604 P38753 - 15086794 - X 2 P0CT04 P38753 - 11283351 - X 2 P40453 P38753 - 11743162 - X 2 P38753 P39743 - 10992286 - X 2 P38753 Q03935 - 11283351 - X 2 P38753 Q06108 - 11743162 - X 2 P38753 Q08491 - 11743162 - X 2 P38753 P40325 - 11283351 - X 2 P38753 Q04439 - 11743162 - X 2 P48524 P38753 - 11743162 - X 2 P40343 P38753 - 11805826 - X 2 P40343 P38753 - 11805826 - X 2 P40343 P38753 - 15044803 - X 2 P40343 P38753 - 11283351 - X 2 P40343 P38753 - 10688190 - X 2 P40343 P38753 - 15086794 - X 2 P36037 P38753 - 11743162 - X 2 Q06604 P38753 - 11743162 - X 2 P38753 - 10688190,11743162 - X 2 P38753 P38351 - 11743162 - X 2 P38753 - 10688190 - X 2 P40073 P38753 - 11743162 - X 2 P33122 P38753 two hybrid 22875988 direct interaction X 2 O13527 P38753 two hybrid 11743162 direct interaction X 2 Q02207 P38753 two hybrid 19841731 direct interaction X 2 Q12446 P38753 two hybrid 19841731 direct interaction X 2 P38266 P38753 two hybrid 19841731 direct interaction X 2 P39008 P38753 two hybrid 19841731 direct interaction X 2 P39013 P38753 two hybrid 22875988 direct interaction X 2 P41913 P38753 two hybrid 19841731 direct interaction X 2 P25368 P38753 two hybrid 19841731 direct interaction X 2 P40460 P38753 two hybrid 19841731 direct interaction X 2 P40341 P38753 two hybrid 19841731 direct interaction X 2 Q12168 P38753 two hybrid 19841731 direct interaction X 2 Q03973 P38753 two hybrid 11743162 direct interaction X 2 P07270 P38753 two hybrid 19841731 direct interaction X 2 P25604 P38753 two hybrid 15086794 direct interaction X 2 P25604 P38753 two hybrid 11743162 direct interaction X 2 P25604 P38753 two hybrid 19841731 direct interaction X 2 P40453 P38753 two hybrid 11743162 direct interaction X 2 P40453 P38753 affinity chromatography technology 17079730 physical association X 2 P40453 P38753 affinity chromatography technology 17079730 physical association X 2 P40453 P38753 pull down 17079730 direct interaction X 2 P40453 P38753 two hybrid 19841731 direct interaction X 2 P38753 Q06108 two hybrid 11743162 direct interaction X 2 P38753 Q04439 two hybrid 11743162 direct interaction X 2 P38753 Q08491 two hybrid 11743162 direct interaction X 2 P38753 P38170 affinity chromatography technology 16554755 physical association X 2 P38753 P40325 affinity chromatography technology 17079730 physical association X 2 P38753 P40325 pull down 17079730 direct interaction X 2 P38753 Q01476 affinity chromatography technology 17079730 physical association X 2 P38753 P38753 protein complementation assay 18467557 direct interaction X 2 P38753 Q08491 two hybrid 19841731 direct interaction X 2 P38753 Q12276 two hybrid 19841731 direct interaction X 2 P38753 P31787 two hybrid 19841731 direct interaction X 2 P38753 P35198 two hybrid 19841731 direct interaction X 2 P38753 P38737 affinity chromatography technology 21321079 physical association X 2 P0CH28 P38753 pull down 20150893 direct interaction X 2 P53933 P38753 two hybrid 19841731 direct interaction X 2 P10591 P38753 affinity chromatography technology 22940862 physical association X 2 P48524 P38753 two hybrid 11743162 direct interaction X 2 P40343 P38753 affinity chromatography technology 12055639 physical association X 2 P40343 P38753 two hybrid 15086794 direct interaction X 2 P40343 P38753 two hybrid 15086794 direct interaction X 2 P40343 P38753 affinity chromatography technology 14581452 physical association X 2 P40343 P38753 affinity chromatography technology 16554755 physical association X 2 P40343 P38753 affinity chromatography technology 16429126 physical association X 2 P40343 P38753 affinity chromatography technology 16429126 physical association X 2 P40343 P38753 affinity chromatography technology 17200106 physical association X 2 P40343 P38753 two hybrid 11283351 direct interaction X 2 P40343 P38753 two hybrid 11283351 direct interaction X 2 P40343 P38753 affinity chromatography technology 17543868 physical association X 2 P40343 P38753 x-ray crystallography 17543868 association X 2 P40343 P38753 protein complementation assay 18467557 direct interaction X 2 P40343 P38753 affinity chromatography technology 20826334 physical association X 2 P40343 P38753 pull down 20826334 direct interaction X 2 P40343 P38753 affinity chromatography technology 11805826 physical association X 2 P40343 P38753 affinity chromatography technology 11805826 physical association X 2 P40343 P38753 two hybrid 10688190 direct interaction X 2 P40343 P38753 two hybrid 10688190 direct interaction X 2 P40343 P38753 protein complementation assay 22615397 direct interaction X 2 P36037 P38753 two hybrid 11743162 direct interaction X 2 P36037 P38753 pull down 24607902 direct interaction X 2 P36037 P38753 pull down 24607902 direct interaction X 2 P36037 P38753 x-ray crystallography 24607902 association X 2 P36037 P38753 affinity chromatography technology 18508771 physical association X 2 P36037 P38753 two hybrid 19841731 direct interaction X 2 Q12245 P38753 two hybrid 19841731 direct interaction X 2 P39940 P38753 two hybrid 15086794 direct interaction X 2 P39940 P38753 affinity chromatography technology 17079730 physical association X 2 P39940 P38753 pull down 17079730 direct interaction X 2 P05085 P38753 two hybrid 19841731 direct interaction X 2 P11484 P38753 affinity chromatography technology 22940862 physical association X 2 P0CG63 P38753 affinity chromatography technology 12055639 physical association X 2 P0CG63 P38753 affinity chromatography technology 23749301 physical association X 2 P0CG63 P38753 affinity chromatography technology 17644757 physical association X 2 P0CG63 P38753 unspecified method 12750381 direct interaction X 2 P0CG63 P38753 affinity chromatography technology 22106047 physical association X 2 P0CG63 P38753 affinity chromatography technology 22493318 physical association X 2 Q06604 P38753 two hybrid 11743162 direct interaction X 2 Q03081 P38753 two hybrid 19841731 direct interaction X 2 P38187 P38753 two hybrid 19841731 direct interaction X 2 P38236 P38753 two hybrid 22875988 direct interaction X 2 P39992 P38753 affinity chromatography technology 16554755 physical association X 2 P38753 two hybrid 11743162 direct interaction X 2 P38753 P38351 two hybrid 11743162 direct interaction X 2 P38753 Q12242 affinity chromatography technology 17079730 physical association X 2 P38753 Q00955 two hybrid 19841731 direct interaction X 2 P38753 P32790 two hybrid 19841731 direct interaction X 2 P38753 P25628 two hybrid 19841731 direct interaction X 2 P40150 P38753 biochemical 23332755 association X 2 P14922 P38753 two hybrid 19841731 direct interaction X 2 Q12348 P38753 affinity chromatography technology 21289098 physical association X 2 P40073 P38753 two hybrid 11743162 direct interaction X 2 P10080 P38753 two hybrid 19841731 direct interaction X 2 A2P2R3 P38753 two hybrid 19841731 direct interaction X 2 Q03973 P38753 two hybrid 11743162 physical association X 2 P25604 P38753 two hybrid 11743162 physical association X 2 P40453 P38753 two hybrid 11743162 physical association X 2 P38753 Q03935 two hybrid pooling approach 11283351 physical association X 2 P38753 P40325 two hybrid pooling approach 11283351 physical association X 2 P38753 Q06108 two hybrid 11743162 physical association X 2 P38753 Q04439 two hybrid 11743162 physical association X 2 P38753 Q08491 two hybrid 11743162 physical association X 2 P38753 P05759 affinity chromatography technology 12055639 physical association X 2 P48524 P38753 two hybrid 11743162 physical association X 2 P40343 P38753 inferred by author 11805826 direct interaction X 2 P40343 P38753 coimmunoprecipitation 12055639 direct interaction X 2 P40343 P38753 tandem affinity purification 11805826 direct interaction X 2 P40343 P38753 two hybrid pooling approach 11283351 direct interaction X 2 P40343 P38753 two hybrid pooling approach 11283351 direct interaction X 2 P40343 P38753 two hybrid 10688190 direct interaction X 2 P40343 P38753 molecular sieving 20305637 direct interaction X 2 P40343 P38753 two hybrid 10688190 direct interaction X 2 P40343 P38753 pull down 20305637 direct interaction X 2 P40343 P38753 tandem affinity purification 11805826 direct interaction X 2 P36037 P38753 two hybrid 11743162 physical association X 2 Q06604 P38753 two hybrid 11743162 physical association X 2 P0CT05 P38753 two hybrid pooling approach 11283351 physical association X 2 P38753 two hybrid 11743162 physical association X 2 P38753 P38351 two hybrid 11743162 physical association X 2 P38753 two hybrid 10688190 physical association X 2 P40073 P38753 two hybrid 11743162 physical association X 2 P38753 tandem affinity purification 11805826 association C 3 O13527 P38753 two hybrid array 11743162 physical association X 2 Q02207 P38753 two hybrid pooling approach 19841731 physical association X 2 Q12446 P38753 two hybrid pooling approach 19841731 physical association X 2 P38266 P38753 two hybrid pooling approach 19841731 physical association X 2 P39008 P38753 two hybrid array 19841731 physical association X 2 P40563 P38753 peptide array 19841731 direct interaction X 2 P40563 P38753 peptide array 19841731 direct interaction X 2 P40563 P38753 peptide array 19841731 direct interaction X 2 P40563 P38753 peptide array 19841731 direct interaction X 2 P41913 P38753 two hybrid array 19841731 physical association X 2 P25368 P38753 two hybrid pooling approach 19841731 physical association X 2 P40460 P38753 two hybrid pooling approach 19841731 physical association X 2 P40341 P38753 two hybrid pooling approach 19841731 physical association X 2 P47043 P38753 inferred by author 19841731 direct interaction X 2 Q12168 P38753 peptide array 19841731 direct interaction X 2 Q12168 P38753 two hybrid array 19841731 physical association X 2 Q03973 P38753 two hybrid array 11743162 physical association X 2 P53094 P38753 inferred by author 19841731 direct interaction X 2 P32621 P38753 inferred by author 19841731 direct interaction X 2 P40959 P38753 inferred by author 19841731 direct interaction X 2 P07270 P38753 two hybrid array 19841731 physical association X 2 P47114 P38753 inferred by author 19841731 direct interaction X 2 P25604 P38753 two hybrid array 11743162 physical association X 2 P25604 P38753 inferred by author 19841731 direct interaction X 2 P25604 P38753 peptide array 19841731 direct interaction X 2 P25604 P38753 two hybrid pooling approach 19841731 physical association X 2 P0CT04 P38753 two hybrid fragment pooling approach 11283351 physical association X 2 P40453 P38753 two hybrid array 11743162 physical association X 2 P40453 P38753 inferred by author 19841731 direct interaction X 2 P40453 P38753 peptide array 19841731 direct interaction X 2 P40453 P38753 two hybrid array 19841731 physical association X 2 P40453 P38753 two hybrid pooling approach 19841731 physical association X 2 P38753 Q03935 two hybrid fragment pooling approach 11283351 physical association X 2 P38753 P40325 two hybrid fragment pooling approach 11283351 physical association X 2 P38753 Q01532 two hybrid array 11743162 physical association X 2 P38753 Q06108 two hybrid array 11743162 physical association X 2 P38753 Q04439 two hybrid array 11743162 physical association X 2 P38753 Q08491 two hybrid array 11743162 physical association X 2 P38753 P38170 tandem affinity purification 16554755 physical association X 2 P38753 P38753 dihydrofolate reductase reconstruction 18467557 physical association X 2 P38753 P40351 inferred by author 19841731 direct interaction X 2 P38753 P08458 peptide array 19841731 direct interaction X 2 P38753 P49095 peptide array 19841731 direct interaction X 2 P38753 P31787 two hybrid array 19841731 physical association X 2 P38753 P35198 two hybrid array 19841731 physical association X 2 P38753 Q08491 two hybrid pooling approach 19841731 physical association X 2 P38753 Q12276 two hybrid pooling approach 19841731 physical association X 2 P38753 P0CG53 surface plasmon resonance 20150893 direct interaction X 2 P38753 P0CG53 surface plasmon resonance 20150893 direct interaction X 2 P07245 P38753 inferred by author 19841731 direct interaction X 2 P53933 P38753 two hybrid pooling approach 19841731 physical association X 2 P48524 P38753 two hybrid array 11743162 physical association X 2 P40343 P38753 two hybrid 10688190 physical association X 2 P40343 P38753 two hybrid 10688190 physical association X 2 P40343 P38753 two hybrid fragment pooling approach 11283351 physical association X 2 P40343 P38753 two hybrid fragment pooling approach 11283351 physical association X 2 P40343 P38753 tandem affinity purification 16429126 physical association X 2 P40343 P38753 inferred by author 16429126 physical association X 2 P40343 P38753 inferred by author 16554755 association X 2 P40343 P38753 tandem affinity purification 16554755 physical association X 2 P40343 P38753 dihydrofolate reductase reconstruction 18467557 physical association X 2 P40343 P38753 dihydrofolate reductase reconstruction 18467557 physical association X 2 P36037 P38753 two hybrid array 11743162 physical association X 2 P36037 P38753 pull down 18508771 physical association X 2 P36037 P38753 two hybrid pooling approach 19841731 physical association X 2 Q12245 P38753 two hybrid pooling approach 19841731 physical association X 2 P38753 tandem affinity purification 16429126 association C 3 P38753 tandem affinity purification 11805826 association C 3 P38753 tandem affinity purification 11805826 association C 3 P05085 P38753 two hybrid pooling approach 19841731 physical association X 2 P53717 P38753 two hybrid 10688190 physical association X 2 P41832 P38753 inferred by author 19841731 direct interaction X 2 Q06604 P38753 two hybrid array 11743162 physical association X 2 P40494 P38753 peptide array 19841731 direct interaction X 2 Q03081 P38753 two hybrid array 19841731 physical association X 2 P38187 P38753 two hybrid pooling approach 19841731 physical association X 2 P39992 P38753 tandem affinity purification 16554755 physical association X 2 P38224 P38753 inferred by author 19841731 direct interaction X 2 P38753 P38351 two hybrid array 11743162 physical association X 2 P38753 P38351 inferred by author 19841731 direct interaction X 2 P38753 P14772 inferred by author 19841731 direct interaction X 2 P38753 Q00955 inferred by author 19841731 direct interaction X 2 P38753 P53169 peptide array 19841731 direct interaction X 2 P38753 P25628 two hybrid array 19841731 physical association X 2 P38753 Q00955 two hybrid pooling approach 19841731 physical association X 2 P38753 P32790 two hybrid pooling approach 19841731 physical association X 2 P14922 P38753 two hybrid array 19841731 physical association X 2 P40073 P38753 two hybrid array 11743162 physical association X 2 P10080 P38753 two hybrid pooling approach 19841731 physical association X 2 Q03973 P38753 two hybrid 11743162 - X 2 P25604 P38753 two hybrid 11743162 - X 2 P0CT04 P38753 two hybrid 11283351 - X 2 P40453 P38753 two hybrid 11743162 - X 2 P38753 Q08491 two hybrid 11743162 - X 2 P38753 Q06108 two hybrid 11743162 - X 2 P38753 Q12114 interaction detection method 14764870 - X 2 P38753 Q03935 two hybrid 11283351 - X 2 P38753 P40325 two hybrid 11283351 - X 2 P38753 Q04439 two hybrid 11743162 - X 2 P38753 Q01532 two hybrid 11743162 - X 2 P48524 P38753 two hybrid 11743162 - X 2 P40343 P38753 two hybrid 11283351 - X 2 P40343 P38753 two hybrid 10688190 - X 2 P40343 P38753 two hybrid 11283351 - X 2 P36037 P38753 two hybrid 11743162 - X 2 P38753 mass spectrometry studies of complexes 11805826 - C 4 P38753 mass spectrometry studies of complexes 11805826 - C 4 P48363 P38753 interaction detection method 14764870 - X 2 P53717 P38753 two hybrid 10688190 - X 2 Q06604 P38753 two hybrid 11743162 - X 2 P38753 P40005 interaction detection method 14764870 - X 2 P38753 P38351 two hybrid 11743162 - X 2 P40073 P38753 two hybrid 11743162 - X 2

PPI - HINT Gene A Gene B PMID Method Quality A2P2R3 HSE1 19841731 0018 HT TY1B-A HSE1 11743162,11743162 0397,0018 HT ARG81 HSE1 19841731,19841731 0398,0018 HT PHO4 HSE1 19841731,19841731 0397,0018 HT SPS1 HSE1 19841731 0081 HT PBI2 HSE1 11283351 0399 HT PBI2 HSE1 11283351,11283351,11283351 0018,0399,0398 HT SBP1 HSE1 19841731,19841731 0398,0018 HT CYC8 HSE1 19841731,19841731 0397,0018 HT RRP7 HSE1 19841731,19841731 0398,0018 HT STP22 HSE1 15086794,19841731,11743162,19841731,11743162,19841731,19841731 0018,0018,0397,0363,0018,0398,0081 LC,HT ARE1 HSE1 19841731,19841731 0397,0018 HT ACB1 HSE1 19841731,19841731 0397,0018 HT SLA1 HSE1 19841731,19841731 0398,0018 HT TYE7 HSE1 22875988 0018 HT MTH1 HSE1 19841731,19841731 0397,0018 HT DOA1 HSE1 19841731,11743162,11743162,24607902,19841731,24607902 0018,0397,0018,0114,0398,0096 HT,LC UBP13 HSE1 19841731,19841731 0398,0018 HT MUM2 HSE1 22875988 0018 HT AIM3 HSE1 19841731,19841731 0398,0018 HT PAF1 HSE1 11743162,11743162 0397,0018 HT HSE1 HSE1 18467557,18467557 0090,0111 HT HSE1 POP2 19841731,19841731 0397,0018 HT HSE1 END3 22875988 0018 HT HSE1 RVS167 10992286 0018 LC HSE1 RSP5 15086794 0018 LC HSE1 SHO1 11743162,11743162 0397,0018 HT HSE1 SSB2 23332755 0401 LC HSE1 HUA1 11283351,11283351,11283351 0018,0399,0398 HT HSE1 YTA12 19841731,19841731 0398,0018 HT HSE1 VPS27 18467557,12055639,20305637,17543868,11283351,20305637,10688190,11283351,10688190,12055639,22615397,15086794,11283351,18467557,17543868 0111,0019,0071,0004,0398,0096,0397,0399,0018,0004,0090,0018,0018,0090,0114 HT,LC HSE1 UBP7 19841731,11743162,19841731,11743162,19841731,19841731,19841731 0018,0397,0363,0018,0397,0398,0081 HT HSE1 NDC80 19841731,19841731 0398,0018 HT HSE1 PRK1 19841731 0081 HT HSE1 AIM21 19841731 0081 HT HSE1 GDS1 19841731,19841731 0397,0018 HT HSE1 BUL1 11743162,11743162 0397,0018 HT HSE1 GCV2 19841731 0081 HT HSE1 YBP2 19841731 0081 HT HSE1 P53717 10688190,10688190 0397,0018 HT HSE1 APP1 19841731,19841731 0398,0018 HT HSE1 ACC1 19841731,19841731,19841731 0398,0363,0018 HT HSE1 LAP3 11743162,11743162 0397,0018 HT HSE1 FOX2 19841731,19841731 0398,0018 HT HSE1 MET31 19841731,19841731 0397,0018 HT HSE1 YAP6 11283351,11283351,11283351 0018,0399,0398 HT HSE1 HMO1 11743162,11743162 0397,0018 HT HSE1 MYO5 11743162,11743162 0397,0018 HT HSE1 RGC1 11743162,11743162 0397,0018 HT HSE1 BSP1 11743162,11743162 0397,0018 HT HSE1 SKI7 11743162,19841731,11743162,19841731 0397,0398,0018,0018 HT HSE1 ACF2 19841731,19841731,19841731 0397,0081,0018 HT HSE1 POC4 19841731,19841731 0398,0018 HT HSE1 HER1 19841731,19841731 0398,0018 HT HSE1 LAS17 19841731,19841731 0398,0018 HT RPS31 HSE1 12055639 0004 LC ADE3 HSE1 19841731 0363 LC UBI4 HSE1 12750381,12055639,22106047,22493318 0096,0004,0004,0004 LC SSA1 HSE1 22940862 0004 HT SSB1 HSE1 22940862 0004 HT BPT1 HSE1 19841731 0363 LC STP22 HSE1 19841731,19841731,19841731,19841731 0018,0363,0398,0081 LC GDA1 HSE1 19841731 0363 LC DOA1 HSE1 18508771,24607902,18508771,24607902 0096,0114,0004,0096 LC BRN1 HSE1 16554755,16554755 0676,0004 HT FIG1 HSE1 19841731 0363 LC PAF1 HSE1 19841731 0363 LC ECM29 HSE1 21321079 0004 LC HSE1 HSE1 11805826,11805826 0676,0007 HT HSE1 RSP5 17079730,17079730 0096,0004 LC HSE1 P39992 16554755,16554755 0676,0004 HT HSE1 SSB2 23332755 0401 LC HSE1 HUA1 17079730,17079730 0004,0096 LC HSE1 VPS27 12055639,26601941,17200106,14581452,20305637,20826334,17543868,20305637,11805826,16429126,12055639,16554755,16554755,16429126,20826334,11805826,16554755,16429126,11805826,11805826,17543868 0019,0004,0004,0004,0071,0004,0004,0096,0363,0363,0004,0363,0676,0676,0096,0004,0004,0004,0676,0007,0114 LC,HT HSE1 ALG8 19841731 0363 LC HSE1 UBP7 17079730,19841731,19841731,19841731,17079730,19841731,19841731 0004,0018,0363,0397,0096,0398,0081 LC HSE1 MVP1 19841731 0363 LC HSE1 BNI1 19841731 0363 LC HSE1 ZAP1 19841731 0363 LC HSE1 P47114 19841731 0363 LC HSE1 MDS3 19841731 0363 LC HSE1 ACC1 19841731,19841731,19841731 0398,0363,0018 LC HSE1 UBP2 17079730 0004 LC HSE1 ATG17 23904270 0004 LC HSE1 RUP1 17079730 0004 LC HSE1 RRI2 21289098 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53094 P38753 MDS3 HSE1 0.183 19841731 Q12348 P38753 RRI2 HSE1 0.126 21289098 P38753 P25628 HSE1 ARE1 0.376 19841731 P38753 P0CG63 HSE1 UBI4 0.309 12750381 P38753 P01095 HSE1 PBI2 0.126 11283351 P38753 P07245 HSE1 ADE3 0.183 19841731 Q08491 P38753 SKI7 HSE1 0.539 11743162,19841731 Q12168 P38753 ACF2 HSE1 0.583 19841731 P38753 P25604 HSE1 STP22 0.681 11743162,19841731 P38753 P31787 HSE1 ACB1 0.286 19841731 P38753 P38170 HSE1 BRN1 0.236 16554755 P39992 P38753 P39992 HSE1 0.236 16554755 P40453 P38753 UBP7 HSE1 0.765 11743162,19841731 P38753 P38753 HSE1 HSE1 0.436 11805826,18467557 Q00955 P38753 ACC1 HSE1 0.416 19841731 P40343 P38753 VPS27 HSE1 0.985 10688190,26601941,14581452,18467557,12055639,16554755,11283351,20826334,11805826,22615397,16429126 P38753 P35198 HSE1 MTH1 0.286 19841731 P38753 P38187 HSE1 UBP13 0.286 19841731 P38753 P38224 HSE1 FIG1 0.332 19841731 P38753 P38266 HSE1 AIM3 0.354 19841731 P38753 P38351 HSE1 PAF1 0.507 11743162,19841731 P38753 P38737 HSE1 ECM29 0.126 21321079 P38753 A2P2R3 HSE1 A2P2R3 0.183 19841731 P38753 O13527 HSE1 TY1B-A 0.286 11743162 P38753 P05085 HSE1 ARG81 0.354 19841731 P38753 P07270 HSE1 PHO4 0.286 19841731 P38753 P08458 HSE1 SPS1 0.183 19841731 P38753 P0CG53 HSE1 UBB 0.309 20150893 P38753 P0CH28 HSE1 UBC 0.309 20150893 P38753 P0CT04 HSE1 PBI2 0.126 11283351 P38753 P10080 HSE1 SBP1 0.286 19841731 P38753 P14772 HSE1 BPT1 0.183 19841731 P38753 P14922 HSE1 CYC8 0.354 19841731 P38753 P25368 HSE1 RRP7 0.354 19841731 P38753 P32621 HSE1 GDA1 0.332 19841731 P38753 P32790 HSE1 SLA1 0.354 19841731 P40073 P38753 SHO1 HSE1 0.286 11743162 P40325 P38753 HUA1 HSE1 0.236 11283351 P40494 P38753 PRK1 HSE1 0.332 19841731 P40563 P38753 AIM21 HSE1 0.183 19841731 P41832 P38753 BNI1 HSE1 0.332 19841731 P47043 P38753 ZAP1 HSE1 0.332 19841731 P47114 P38753 P47114 HSE1 0.332 19841731 P48524 P38753 BUL1 HSE1 0.286 11743162 P53169 P38753 YBP2 HSE1 0.183 19841731 P53717 P38753 P53717 HSE1 0.21 10688190 P61864 P38753 RPL40A HSE1 0.033 12055639 Q01532 P38753 LAP3 HSE1 0.286 11743162 Q02207 P38753 FOX2 HSE1 0.286 19841731 Q03973 P38753 HMO1 HSE1 0.286 11743162 Q04439 P38753 MYO5 HSE1 0.286 11743162 Q06108 P38753 RGC1 HSE1 0.286 11743162 Q06604 P38753 BSP1 HSE1 0.286 11743162 Q12245 P38753 POC4 HSE1 0.286 19841731 Q12276 P38753 HER1 HSE1 0.354 19841731 Q12446 P38753 LAS17 HSE1 0.286 19841731 P39008 P38753 POP2 HSE1 0.376 19841731 P40341 P38753 YTA12 HSE1 0.376 19841731 P40351 P38753 ALG8 HSE1 0.183 19841731 P40460 P38753 TID3 HSE1 0.376 19841731 P38753 P36037 HSE1 DOA1 0.88 18508771,19841731,24607902,11743162 P45978 P38753 SCD6 HSE1 0.309 27776129 P40959 P38753 MVP1 HSE1 0.183 19841731 P49095 P38753 GCV2 HSE1 0.183 19841731 P41913 P38753 GDS1 HSE1 0.376 19841731 Q06410 P38753 ATG17 HSE1 0.126 23904270 Q03081 P38753 MET31 HSE1 0.376 19841731 Q03935 P38753 YAP6 HSE1 0.21 11283351 P53933 P38753 APP1 HSE1 0.376 19841731