PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus MET30 UPF0695 membrane protein YOR390W 14690591 intact exp MET30 INO80 14690591 intact exp MET30 Putative transcriptional regulatory protein YJL206C 14690591 intact exp HO MET30 24389104 biogrid exp PEX18 MET30 14690591 intact exp MET30 Uncharacterized protein YOL036W 14690591 intact exp MET30 VPS74 14690591 intact exp HSP26 MET30 11805837 dip exp RPS27A MET30 14690591 intact exp MAK11 MET30 14690591 intact exp SSB1 MET30 19536198 intact exp MET30 RDL1 14690591 intact exp MET30 Putative uncharacterized protein YDR095C 10688190,14690591 mint,intact,dip exp RPL40A MET30 11805837 intact,dip exp SAM1 MET30 11805837 dip exp PTC1 MET30 14690591 intact exp UBI4 MET30 24648496,21070969,11805837 biogrid exp Uncharacterized protein YBR138C MET30 10688190,14690591 biogrid,i2d,mint,intact,dip exp MET30 BNR1 14690591 intact exp MET30 SDS3 14690591 intact exp MET30 Putative uncharacterized protein YIR044C 14690591 intact exp DBP2 MET30 14690591 intact exp SUC2 MET30 14690591 intact exp GPM1 MET30 11805837 dip exp SPO23 MET30 14690591 intact exp UBA4 MET30 14690591 intact exp MET30 MPM1 11805837 dip exp MET30 YVC1 10688190,14690591 mint,intact,dip exp KIN3 MET30 14690591 intact exp MET30 BSC6 14690591 intact exp TFC1 MET30 14690591 intact exp SEA4 MET30 14690591 intact exp MET30 SRL2 10688190,14690591 biogrid,i2d,mint,intact,dip exp MET30 Uncharacterized protein YDL241W 14690591 intact exp MET30 PIG1 14690591 intact exp VMA2 MET30 11805837 dip exp MET30 GIM3 19536198 intact exp MET30 FLO9 14690591 intact exp IMA3 MET30 14690591 intact exp TUB2 MET30 11805837 dip exp PEX34 MET30 14690591 intact exp Putative uncharacterized protein YLR269C MET30 14690591 intact exp ERG7 MET30 14690591 intact exp MET30 CAK1 16554755 intact exp NIP100 MET30 14690591 intact exp TAT1 MET30 14690591 intact exp TEF1, TEF2 MET30 11805837 dip exp PGI1 MET30 11805837 dip exp PTK1 MET30 14690591 intact exp SSA1 MET30 19536198 intact exp MET30 Uncharacterized protein YDR114C 14690591 intact exp MET30 EDC3 10688190,14690591 biogrid,i2d,mint,intact,dip exp MET30 ENT2 14690591 intact exp MET30 Uncharacterized protein YLL007C 14690591 intact exp LTE1 MET30 14690591 intact exp MET30 DPH1 14690591 intact exp MET30 HOF1 14690591 intact exp MET30 APP1 14690591 intact exp SSC1 MET30 11805837 dip exp MET30 Putative uncharacterized protein YDL094C 14690591 intact exp Inactive deaminase YBR284W MET30 14690591 intact exp HSP82 MET30 11805837 dip exp MET30 SSB2 23332755,19536198 biogrid,intact exp TEF4 MET30 11805837 biogrid,intact,dip exp HXK1 MET30 11805837 dip exp MET30 Putative acetyltransferase YJL218W 14690591 intact exp MET30 MET30 14660673, 23023127 biogrid,intact exp, pred MET30 MET32 21172660, 23023127 biogrid exp, pred MET30 BIT61 10688190,14690591, 23023127 biogrid,i2d,mint,intact,dip exp, pred MET30 NTA1 14690591, 23023127 intact exp, pred GPA1 MET30 15687504, 23023127 biogrid exp, pred MET30 OAF1 14690591, 23023127 intact exp, pred MCM10 MET30 14690591, 23023127 intact exp, pred CDC48 MET30 23000173,11805837, 23023127 biogrid,dip exp, pred SEC18 MET30 18719252, 23023127 biogrid,intact exp, pred BIT2 MET30 10688190,14690591, 23023127 biogrid,i2d,mint,intact,dip exp, pred MCM7 MET30 15870262, 23023127 biogrid exp, pred SLX5 MET30 14690591, 23023127 intact exp, pred MET30 CWC25 10688190,14690591, 23023127 i2d,mint,intact,dip exp, pred MET30 PXR1 14690591, 23023127 intact exp, pred MET30 HRT1 24648496,19882662,11805837, 23023127 biogrid,mint,intact,dip exp, pred MET30 CDC53 24648496,23267104,9716410,10582239,19882662,9499404,14690591,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred SIS1 MET30 11805837, 23023127 biogrid,intact,dip exp, pred MET30 MET31 11805837, 23023127 biogrid,intact,dip exp, pred PAN1 MET30 14690591, 23023127 intact exp, pred MET30 IPI3 11283351, 23023127 i2d,mint,intact,dip exp, pred MET30 SKP1 12582129,22817900,21172660,14660673,9499404,11805837,24648496,11283612,10688190,9716410,23000173,10582239,19882662,15660125,18719252,10637232,14690591,20581845, 23023127 biogrid,i2d,mint,intact,dip exp, pred YDJ1 MET30 11805837, 23023127 dip exp, pred MNS1 MET30 10688190,14690591, 23023127 biogrid,i2d,mint,intact,dip exp, pred MET30 STR2 18719252, 23023127 biogrid,intact exp, pred CDC23 MET30 14690591, 23023127 intact exp, pred FZF1 MET30 14690591, 23023127 intact exp, pred RET1 MET30 10688190,14690591, 23023127 mint,intact,dip exp, pred MET30 SGT1 14690591, 23023127 intact exp, pred POL1 MET30 14690591, 23023127 intact exp, pred ARG81 MET30 14690591, 23023127 intact exp, pred MET30 Putative cystathionine gamma-synthase YML082W 18719252, 23023127 biogrid,intact exp, pred ATG12 MET30 14690591, 23023127 intact exp, pred MET30 NAF1 14690591, 23023127 intact exp, pred CDC34 MET30 9716410,16554755, 23023127 biogrid,i2d,mint,intact exp, pred MET30 UBC7 14690591, 23023127 intact exp, pred SNF5 MET30 14690591, 23023127 intact exp, pred TUP1 MET30 14690591, 23023127 intact exp, pred SWE1 MET30 9716410, 23023127 biogrid,i2d,dip exp, pred MCM4 MET30 15870262, 23023127 biogrid exp, pred MET30 RUB1 11805837, 23023127 biogrid,intact,dip exp, pred MET30 CDC45 15870262, 23023127 biogrid exp, pred MET4 MET30 10975521,21172660,15660125,11805837,24389104,8524217,23000173,15883825,10637232,14690591,17157252, 23023127 biogrid,i2d,intact,dip exp, pred TAF14 MET30 23023127 pred MET30 TAF3 23023127 pred MET30 SER3 23023127 pred CDC12 MET30 23023127 pred MET30 ORC5 23023127 pred CAD1 MET30 23023127 pred MET30 RPN4 23023127 pred MET30 TAF9 23023127 pred MET30 TAF12 23023127 pred MET30 UBI4 23023127 pred MET30 APC11 23023127 pred CDC16 MET30 23023127 pred MET30 CDC40 23023127 pred UBC4 MET30 23023127 pred ADE3 MET30 23023127 pred MET30 TAF6 23023127 pred MET30 TAF1 23023127 pred MET30 SFH1 23023127 pred CDC20 MET30 23023127 pred MET30 RSP5 23023127 pred MET30 APC1 23023127 pred MET30 MET5 23023127 pred MET30 PIP2 23023127 pred MET30 DPB11 23023127 pred XRN1 MET30 23023127 pred CUP2 MET30 23023127 pred ORC2 MET30 23023127 pred TAF5 MET30 23023127 pred MET30 SEC13 23023127 pred CDC13 MET30 23023127 pred CDC7 MET30 23023127 pred SWI5 MET30 23023127 pred CDC27 MET30 23023127 pred RSC6 MET30 23023127 pred CDC4 MET30 23023127 pred SKN7 MET30 23023127 pred MET30 ORC4 23023127 pred MET30 RSC8 23023127 pred ORC6 MET30 23023127 pred SIS2 MET30 23023127 pred PHO85 MET30 23023127 pred MET30 TAF10 23023127 pred ACE2 MET30 23023127 pred TOR2 MET30 23023127 pred CDC5 MET30 23023127 pred PRP4 MET30 23023127 pred CCR4 MET30 23023127 pred MET30 YRB1 23023127 pred TAF2 MET30 23023127 pred MET30 TAH11 23023127 pred MET30 CDH1 23023127 pred MET30 MET10 23023127 pred MET30 RSC3 23023127 pred MET30 HAT2 23023127 pred MET30 MOB1 23023127 pred MET30 MET28 23023127 pred MET30 UBC9 23023127 pred CDC25 MET30 23023127 pred FAS2 MET30 23023127 pred UBA1 MET30 23023127 pred MET30 APC4 23023127 pred MET30 ORC1 23023127 pred RPN2 MET30 23023127 pred MET30 TAF11 23023127 pred MET30 TAF7 23023127 pred GRR1 MET30 23023127 pred TOR1 MET30 23023127 pred TAF13 MET30 23023127 pred UBC5 MET30 23023127 pred SDS22 MET30 23023127 pred MET30 UBA2 23023127 pred GLC7 MET30 23023127 pred MCM1 MET30 23023127 pred CMP2 MET30 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P39014 - 11805837 - C 8 P39998 P39014 - 10688190 - X 2 P39014 Q12018 - 9499404 - X 2 P39014 P52286 - 10688190 - X 2 P39014 P32944 - 9716410 - X 2 P39014 - 8524217 - X 2 P39014 Q12018 - 9716410 - X 2 P39014 Q12020 - 10688190 - X 2 P39014 P53877 - 11283351 - X 2 P39014 P52286 - 9716410 - X 2 P39014 P52286 - 15660125 - X 2 P32906 P39014 - 10688190 - X 2 P39014 - 10688190 - X 2 P39014 - 11805837 - C 5 P39014 - 11805837 - C 3 P39014 - 11805837 - C 4 P14682 P39014 - 9716410 - X 2 P39014 - 10688190 - X 2 P39014 P47041 - 10688190 - X 2 P53854 P39014 - 14690591 - X 2 P39998 P39014 two hybrid 10688190 direct interaction X 2 P39014 P52286 affinity chromatography technology 23000173 physical association X 2 P39014 P52286 affinity chromatography technology 23000173 physical association X 2 P39014 P32389 affinity chromatography technology 23000173 physical association X 2 P39014 P32389 affinity chromatography technology 10637232 physical association X 2 P39014 P52286 affinity chromatography technology 10637232 physical association X 2 P39014 Q12018 affinity chromatography technology 9499404 physical association X 2 P39014 P32389 affinity chromatography technology 10975521 physical association X 2 P39014 Q12018 affinity chromatography technology 9716410 physical association X 2 P39014 P52286 affinity chromatography technology 9716410 physical association X 2 P39014 P32944 affinity chromatography technology 9716410 physical association X 2 P39014 Q12018 two hybrid 9499404 direct interaction X 2 P39014 P32389 two hybrid 10637232 direct interaction X 2 P39014 P32389 two hybrid 8524217 direct interaction X 2 P39014 P52286 two hybrid 11283612 direct interaction X 2 P39014 Q12018 affinity chromatography technology 10582239 physical association X 2 P39014 Q12018 affinity chromatography technology 10582239 physical association X 2 P39014 P52286 affinity chromatography technology 10582239 physical association X 2 P39014 P52286 protein complementation assay 22817900 direct interaction X 2 P39014 P52286 affinity chromatography technology 14660673 physical association X 2 P39014 P52286 two hybrid 14660673 direct interaction X 2 P39014 P52286 two hybrid 12582129 direct interaction X 2 P39014 P52286 affinity chromatography technology 15660125 physical association X 2 P39014 P52286 affinity chromatography technology 15660125 physical association X 2 P39014 P32389 affinity chromatography technology 15660125 physical association X 2 P39014 P32389 affinity chromatography technology 15883825 physical association X 2 P39014 P09932 affinity chromatography technology 24389104 physical association X 2 P39014 P32389 affinity chromatography technology 24389104 physical association X 2 P39014 P52286 affinity chromatography technology 24648496 physical association X 2 P39014 Q12018 affinity chromatography technology 24648496 physical association X 2 P39014 P40150 biochemical 23332755 association X 2 P39014 P38132 imaging technique 15870262 colocalization X 2 P39014 Q08032 imaging technique 15870262 colocalization X 2 P39014 P32389 affinity chromatography technology 17157252 physical association X 2 P39014 P32389 affinity chromatography technology 17157252 physical association X 2 P39014 P52286 two hybrid 18719252 direct interaction X 2 P39014 P08539 two hybrid 15687504 direct interaction X 2 P39014 Q12018 affinity chromatography technology 19882662 physical association X 2 P39014 Q12041 affinity chromatography technology 21172660 physical association X 2 P39014 P32389 affinity chromatography technology 21172660 physical association X 2 P39014 P52286 pull down 21172660 direct interaction X 2 P39014 P52286 affinity chromatography technology 20581845 physical association X 2 P39014 P52286 affinity chromatography technology 20581845 physical association X 2 P39014 P52286 affinity chromatography technology 11805837 physical association X 2 P39014 Q12018 affinity chromatography technology 11805837 physical association X 2 P39014 Q03919 affinity chromatography technology 11805837 physical association X 2 P39014 P32389 affinity chromatography technology 11805837 physical association X 2 P39014 Q12020 two hybrid 10688190 direct interaction X 2 P39014 P52286 two hybrid 10688190 direct interaction X 2 P32906 P39014 two hybrid 10688190 direct interaction X 2 P14682 P39014 affinity chromatography technology 9716410 physical association X 2 P14682 P39014 affinity chromatography technology 16554755 physical association X 2 Q08273 P39014 affinity chromatography technology 24648496 physical association X 2 Q08273 P39014 affinity chromatography technology 11805837 physical association X 2 P0CG63 P39014 pull down 23000173 direct interaction X 2 P0CG63 P39014 biochemical 23583075 association X 2 P0CG63 P39014 affinity chromatography technology 24648496 physical association X 2 P0CG63 P39014 affinity chromatography technology 17644757 physical association X 2 P0CG63 P39014 pull down 21070969 direct interaction X 2 P0CG63 P39014 affinity chromatography technology 11805837 physical association X 2 P0CG63 P39014 affinity chromatography technology 22106047 physical association X 2 P39014 P25694 affinity chromatography technology 23000173 physical association X 2 P39014 P39014 affinity chromatography technology 14660673 physical association X 2 P39014 P30665 imaging technique 15870262 colocalization X 2 P39014 P18759 two hybrid 18719252 direct interaction X 2 P39014 P47164 two hybrid 18719252 direct interaction X 2 P39014 Q04533 two hybrid 18719252 direct interaction X 2 P39014 P36008 affinity chromatography technology 11805837 physical association X 2 P39014 P25294 affinity chromatography technology 11805837 physical association X 2 P39014 Q03081 affinity chromatography technology 11805837 physical association X 2 P39014 P38277 two hybrid 10688190 direct interaction X 2 P39014 P47041 two hybrid 10688190 direct interaction X 2 P38346 P39014 two hybrid 10688190 direct interaction X 2 P39014 anti tag coimmunoprecipitation 11805837 - C 23 P39998 P39014 two hybrid 10688190 physical association X 2 P40364 P39014 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P15992 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P04806 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P0CS90 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P02994 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P25491 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P00950 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P53877 two hybrid pooling approach 11283351 physical association X 2 P39014 Q03919 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P05759 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 Q12020 two hybrid 10688190 physical association X 2 P39014 P52286 affinity chromatography technology 14660673 physical association X 2 P39014 P52286 biochemical 9716410 physical association X 2 P39014 P52286 two hybrid 14660673 physical association X 2 P39014 P52286 two hybrid 10688190 physical association X 2 P39014 P52286 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P32944 biochemical 9716410 physical association X 2 P39014 Q12018 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 Q12018 coimmunoprecipitation 9716410 physical association X 2 P39014 Q12018 two hybrid 9716410 physical association X 2 P39014 Q03831 two hybrid 10688190 physical association X 2 P32906 P39014 two hybrid 10688190 physical association X 2 P39014 anti tag coimmunoprecipitation 11805837 - C 10 Q08273 P39014 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P12709 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P10659 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P02557 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P16140 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P25694 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P02829 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 Q03081 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P25294 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P36008 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P38277 two hybrid 10688190 physical association X 2 P39014 two hybrid 10688190 physical association X 2 P39014 P47041 two hybrid 10688190 physical association X 2 P39014 affinity chromatography technology 10975521 physical association X 2 P39014 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 two hybrid 8524217 physical association X 2 P39014 P22276 two hybrid 10688190 physical association X 2 P53854 P39014 two hybrid 10688190 physical association X 2 Q12324 P39014 two hybrid 10688190 physical association X 2 P39014 pull down 19882662 association C 41 P39014 inferred by author 16554755 association C 12 P39014 anti tag coimmunoprecipitation 9499404 association C 6 P39014 anti tag coimmunoprecipitation 14660673 association C 3 P39014 anti tag coimmunoprecipitation 14660673 association C 3 P39014 anti tag coimmunoprecipitation 11805837 association C 8 P39014 pull down 19882662 association C 35 P39998 P39014 two hybrid 10688190 physical association X 2 P39998 P39014 two hybrid array 14690591 physical association X 2 P39720 P39014 two hybrid array 14690591 physical association X 2 P39014 P32389 anti tag coimmunoprecipitation 10637232 physical association X 2 P39014 P52286 anti tag coimmunoprecipitation 10637232 physical association X 2 P39014 P32389 two hybrid 10637232 physical association X 2 P39014 Q12020 two hybrid 10688190 physical association X 2 P39014 Q03831 two hybrid 10688190 physical association X 2 P39014 Q12020 two hybrid 10688190 physical association X 2 P39014 P52286 two hybrid 10688190 physical association X 2 P39014 P53877 two hybrid fragment pooling approach 11283351 physical association X 2 P39014 P52286 pull down 14660673 physical association X 2 P39014 P52286 anti tag coimmunoprecipitation 14660673 physical association X 2 P39014 P52286 two hybrid 14660673 physical association X 2 P39014 Q12020 two hybrid array 14690591 physical association X 2 P39014 P40450 two hybrid array 14690591 physical association X 2 P39014 Q03831 two hybrid array 14690591 physical association X 2 P39014 P38820 two hybrid array 14690591 physical association X 2 P39014 P25584 two hybrid array 14690591 physical association X 2 P39014 P33757 two hybrid array 14690591 physical association X 2 P39014 P40588 two hybrid array 14690591 physical association X 2 P39014 P38164 two hybrid array 14690591 physical association X 2 P39014 O13550 two hybrid array 14690591 physical association X 2 P39014 Q07509 two hybrid array 14690591 physical association X 2 P39014 P07866 two hybrid array 14690591 physical association X 2 P39014 P36002 two hybrid array 14690591 physical association X 2 P39014 P38855 two hybrid array 14690591 physical association X 2 P39014 P16649 two hybrid array 14690591 physical association X 2 P39014 P40354 two hybrid array 14690591 physical association X 2 P39014 P52286 two hybrid array 14690591 physical association X 2 P39014 Q06216 two hybrid array 14690591 physical association X 2 P39014 Q12018 two hybrid array 14690591 physical association X 2 P39014 Q12305 two hybrid array 14690591 physical association X 2 P39014 P53335 two hybrid array 14690591 physical association X 2 P39014 P38150 two hybrid array 14690591 physical association X 2 P39014 P32389 two hybrid array 14690591 physical association X 2 P39014 Q08913 two hybrid array 14690591 physical association X 2 P39014 Q05080 two hybrid array 14690591 physical association X 2 P39014 P22209 two hybrid array 14690591 physical association X 2 P39014 P40487 two hybrid array 14690591 physical association X 2 P39014 P32389 anti tag coimmunoprecipitation 15883825 physical association X 2 P39014 P32389 pull down 15883825 physical association X 2 P39014 P52286 two hybrid 18719252 physical association X 2 P39014 P11484 tandem affinity purification 19536198 association X 2 P39014 P40150 tandem affinity purification 19536198 association X 2 P39014 P53900 tandem affinity purification 19536198 association X 2 P39014 Q12018 anti tag coimmunoprecipitation 19882662 physical association X 2 P39014 P52286 anti tag coimmunoprecipitation 22817900 physical association X 2 P39014 P52286 anti tag coimmunoprecipitation 22817900 physical association X 2 P39014 P52286 protein complementation assay)|MI:0228(cytoplasmic complementation assay)|MI:0230(membrane bound complementation assay 22817900 physical association X 2 P39014 Q12018 miniaturized immunoprecipitation 23267104 direct interaction X 2 P39014 P32389 two hybrid 8524217 physical association X 2 P39014 Q12018 two hybrid 9499404 physical association X 2 P39014 Q12018 two hybrid 9499404 physical association X 2 P32521 P39014 two hybrid array 14690591 physical association X 2 P20484 P39014 two hybrid array 14690591 physical association X 2 P53919 P39014 two hybrid array 14690591 physical association X 2 P53115 P39014 two hybrid array 14690591 physical association X 2 P32906 P39014 two hybrid 10688190 physical association X 2 P32906 P39014 two hybrid array 14690591 physical association X 2 P39014 anti tag coimmunoprecipitation 9499404 association C 5 P39014 pull down 19882662 association C 51 P39014 anti tag coimmunoprecipitation 11805837 association C 5 P39014 anti tag coimmunoprecipitation 11805837 association C 3 P39014 anti tag coimmunoprecipitation 9499404 association C 3 P39014 anti tag coimmunoprecipitation 11805837 association C 4 P14682 P39014 tandem affinity purification 16554755 physical association X 2 P39014 P22276 two hybrid 10688190 physical association X 2 P39014 P38277 two hybrid 10688190 physical association X 2 P39014 P47041 two hybrid 10688190 physical association X 2 P39014 P39014 pull down 14660673 physical association X 2 P39014 P22276 two hybrid array 14690591 physical association X 2 P39014 P39712 two hybrid array 14690591 physical association X 2 P39014 P38277 two hybrid array 14690591 physical association X 2 P39014 P35997 two hybrid array 14690591 physical association X 2 P39014 P0CW40 two hybrid array 14690591 physical association X 2 P39014 Q04597 two hybrid array 14690591 physical association X 2 P39014 P32354 two hybrid array 14690591 physical association X 2 P39014 Q08206 two hybrid array 14690591 physical association X 2 P39014 P32805 two hybrid array 14690591 physical association X 2 P39014 P13382 two hybrid array 14690591 physical association X 2 P39014 P47041 two hybrid array 14690591 physical association X 2 P39014 P38085 two hybrid array 14690591 physical association X 2 P39014 Q07799 two hybrid array 14690591 physical association X 2 P39014 P16522 two hybrid array 14690591 physical association X 2 P39014 Q08280 two hybrid array 14690591 physical association X 2 P39014 P39529 two hybrid array 14690591 physical association X 2 P39014 Q06385 two hybrid array 14690591 physical association X 2 P39014 P32367 two hybrid array 14690591 physical association X 2 P39014 P05085 two hybrid array 14690591 physical association X 2 P39014 P00724 two hybrid array 14690591 physical association X 2 P39014 Q07738 two hybrid array 14690591 physical association X 2 P39014 P40505 two hybrid array 14690591 physical association X 2 P39014 P35182 two hybrid array 14690591 physical association X 2 P39014 Q08446 two hybrid array 14690591 physical association X 2 P39014 P38604 two hybrid array 14690591 physical association X 2 P39014 P18480 two hybrid array 14690591 physical association X 2 P39014 P24783 two hybrid array 14690591 physical association X 2 P39014 P40892 two hybrid array 14690591 physical association X 2 P39014 P33420 two hybrid array 14690591 physical association X 2 P39014 Q05785 two hybrid array 14690591 physical association X 2 P39014 P32828 two hybrid array 14690591 physical association X 2 P39014 Q02159 two hybrid array 14690591 physical association X 2 P39014 Q04533 two hybrid 18719252 physical association X 2 P39014 P18759 two hybrid 18719252 physical association X 2 P39014 P47164 two hybrid 18719252 physical association X 2 P38346 P39014 two hybrid 10688190 physical association X 2 P38346 P39014 two hybrid array 14690591 physical association X 2 P38316 P39014 two hybrid array 14690591 physical association X 2 P53933 P39014 two hybrid array 14690591 physical association X 2 P10591 P39014 tandem affinity purification 19536198 association X 2 P53854 P39014 two hybrid 10688190 physical association X 2 P53854 P39014 two hybrid array 14690591 physical association X 2 Q12324 P39014 two hybrid 10688190 physical association X 2 Q12324 P39014 two hybrid array 14690591 physical association X 2 P39014 confirmational text mining - - C 4 P39998 P39014 two hybrid 10688190 - X 2 P39014 P32944 coimmunoprecipitation 9716410 - X 2 P39014 Q12020 two hybrid 10688190 - X 2 P39014 P32389 interaction detection method - - X 2 P39014 P32389 two hybrid 8524217 - X 2 P39014 P53877 two hybrid 11283351 - X 2 P39014 Q12018 interaction detection method 9716410 - X 2 P39014 Q12018 two hybrid 9499404 - X 2 P39014 Q12018 affinity chromatography technology 9716410 - X 2 P39014 P52286 interaction detection method 9716410 - X 2 P39014 P52286 two hybrid - - X 2 P39014 P52286 two hybrid 10688190 - X 2 P39014 P52286 two hybrid 10688190,9499404 - X 2 P39014 P52286 affinity chromatography technology 9716410 - X 2 P32906 P39014 two hybrid 10688190 - X 2 P39014 mass spectrometry studies of complexes 11805837 - C 11 P39014 mass spectrometry studies of complexes 11805837 - C 11 P14682 P39014 interaction detection method 9716410 - X 2 P14682 P39014 coimmunoprecipitation 9716410 - X 2 P39014 P47041 two hybrid 10688190 - X 2 P39014 P38277 two hybrid 10688190 - X 2 P38346 P39014 two hybrid 10688190 - X 2

PPI - HINT Gene A Gene B PMID Method Quality O13550 MET30 14690591 0397 LC SUC2 MET30 14690591 0397 LC ARG81 MET30 14690591 0397 LC LTE1 MET30 14690591 0397 LC GPA1 MET30 15687504 0018 LC IMA3 MET30 14690591 0397 LC POL1 MET30 14690591 0397 LC CDC34 MET30 9716410,9716410 0004,0019 LC CDC23 MET30 14690591 0397 LC TUP1 MET30 14690591 0397 LC SNF5 MET30 14690591 0397 LC SEC18 MET30 18719252 0018 HT MAK11 MET30 14690591 0397 LC KIN3 MET30 14690591 0397 LC RET1 MET30 10688190,14690591 0018,0397 HT,LC DBP2 MET30 14690591 0397 LC PEX34 MET30 14690591 0397 LC MCM10 MET30 14690591 0397 LC TFC1 MET30 14690591 0397 LC MET4 MET30 8524217,10637232,10637232,14690591,10637232 0018,0007,0004,0397,0018 LC PAN1 MET30 14690591 0397 LC FZF1 MET30 14690591 0397 LC SLX5 MET30 14690591 0397 LC MNS1 MET30 10688190,10688190,14690591 0397,0018,0397 HT,LC SWE1 MET30 9716410,9716410,9716410 0401,0004,0019 LC NIP100 MET30 14690591 0397 LC SPO23 MET30 14690591 0397 LC PTC1 MET30 14690591 0397 LC RPS27A MET30 14690591 0397 LC PTK1 MET30 14690591 0397 LC TAT1 MET30 14690591 0397 LC P38150 MET30 14690591 0397 LC SEA4 MET30 14690591 0397 LC P38277 MET30 10688190,10688190,14690591 0397,0018,0397 HT,LC ATG12 MET30 14690591 0397 LC BIT2 MET30 10688190,10688190,14690591 0397,0018,0397 HT,LC ERG7 MET30 14690591 0397 LC UBA4 MET30 14690591 0397 LC PEX18 MET30 14690591 0397 LC MET30 P39529 14690591 0397 LC MET30 FLO9 14690591 0397 LC MET30 OAF1 14690591 0397 LC MET30 EDC3 10688190,10688190,14690591 0397,0018,0397 HT,LC MET30 SSB2 23332755 0401 LC MET30 NTA1 14690591 0397 LC MET30 BNR1 14690591 0397 LC MET30 DPH1 14690591 0397 LC MET30 SDS3 14690591 0397 LC MET30 P40588 14690591 0397 LC MET30 P40892 14690591 0397 LC MET30 BIT61 10688190,10688190,14690591 0397,0018,0397 HT,LC MET30 STR2 18719252 0018 HT MET30 SKP1 15660125,9716410,9499404,22817900,12582129,11283612,10688190,10688190,15660125,9716410,9499404,14660673,14690591,14660673,18719252,22817900,14660673,14660673 0019,0401,0018,0090,0018,0018,0397,0018,0004,0004,0007,0018,0397,0004,0018,0007,0096,0007 LC,HT MET30 INO80 14690591 0397 LC MET30 PXR1 14690591 0397 LC MET30 CWC25 14690591,10688190,14690591 0018,0018,0397 LC,HT MET30 IPI3 11283351,11283351,11283351 0018,0399,0398 HT MET30 NAF1 14690591 0397 LC MET30 APP1 14690591 0397 LC MET30 UBC7 14690591 0397 LC MET30 Q03831 10688190,14690591 0018,0397 HT,LC MET30 Q04533 18719252 0018 HT MET30 Q04597 14690591 0397 LC MET30 HOF1 14690591 0397 LC MET30 ENT2 14690591 0397 LC MET30 PIG1 14690591 0397 LC MET30 VPS74 14690591 0397 LC MET30 Q07509 14690591 0397 LC MET30 Q07738 14690591 0397 LC MET30 Q07799 14690591 0397 LC MET30 Q08206 14690591 0397 LC MET30 BSC6 14690591 0397 LC MET30 SGT1 14690591 0397 LC MET30 Q08913 14690591 0397 LC MET30 CDC53 9716410,9716410,23267104,9499404,9716410,9499404,9499404,14690591 0018,0019,0946,0004,0004,0018,0007,0397 LC MET30 SRL2 10688190,10688190,14690591 0397,0018,0397 HT,LC MET30 RDL1 14690591 0397 LC MET30 YVC1 10688190,14690591 0018,0397 HT,LC GPM1 MET30 11805837 0007 HT TUB2 MET30 11805837 0007 HT HSP82 MET30 11805837 0007 HT TEF1|TEF2 MET30 11805837 0007 HT HXK1 MET30 11805837 0007 HT RPS31 MET30 11805837 0007 HT HO MET30 24389104 0004 LC UBI4 MET30 11805837,21070969,24648496,21070969,22106047 0004,0004,0004,0096,0004 HT,LC RPL40B MET30 11805837 0007 HT SSC1 MET30 11805837 0007 HT SSA1 MET30 19536198 0676 HT SAM1 MET30 11805837 0007 HT SSB1 MET30 19536198 0676 HT PGI1 MET30 11805837 0007 HT CDC34 MET30 16554755,9716410,16554755,9716410 0004,0004,0676,0019 HT,LC HSP26 MET30 11805837 0007 HT VMA2 MET30 11805837 0007 HT SIS1 MET30 11805837,11805837 0004,0007 HT YDJ1 MET30 11805837 0007 HT CDC48 MET30 23000173,11805837 0004,0007 LC,HT MCM4 MET30 15870262 0428 LC MET4 MET30 15660125,23000173,21172660,10637232,15883825,24389104,11805837,10637232,17157252,10975521,15883825,11805837,10637232,15883825 0004,0004,0004,0007,0007,0004,0004,0004,0004,0004,0004,0007,0018,0096 LC,HT SWE1 MET30 9716410,9716410,9716410 0401,0004,0019 LC TEF4 MET30 11805837,11805837 0004,0007 HT MCM7 MET30 15870262 0428 LC MET30 MET30 14660673,14660673,14660673 0004,0096,0007 LC MET30 SSB2 19536198,23332755 0676,0401 HT,LC MET30 MPM1 11805837 0007 HT MET30 CAK1 16554755 0363 HT MET30 SKP1 15660125,19882662,9716410,20581845,9499404,22817900,23000173,10582239,10637232,11805837,15660125,10637232,9716410,9499404,21172660,11805837,14660673,14660673,22817900,14660673,24648496,14660673 0019,0096,0401,0004,0018,0090,0004,0004,0007,0004,0004,0004,0004,0007,0096,0007,0018,0004,0007,0096,0004,0007 LC,HT MET30 GIM3 19536198 0676 HT MET30 MET31 11805837,11805837 0004,0007 HT MET30 RUB1 11805837,11805837 0004,0007 HT MET30 CDC45 15870262 0428 LC MET30 HRT1 11805837,19882662,24648496,11805837 0004,0096,0004,0007 HT,LC MET30 CDC53 11805837,9716410,9716410,19882662,9499404,9716410,9499404,9499404,10582239,19882662,19882662,24648496,11805837 0004,0018,0019,0096,0004,0004,0018,0007,0004,0004,0007,0004,0007 HT,LC MET30 MET32 21172660 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53115 P39014 INO80 MET30 0.126 14690591 Q04597 P39014 Q04597 MET30 0.126 14690591 P53335 P39014 PXR1 MET30 0.126 14690591 P39014 P24783 MET30 DBP2 0.126 14690591 P39014 P15992 MET30 HSP26 0.126 11805837 Q12305 P39014 RDL1 MET30 0.126 14690591 Q12324 P39014 YVC1 MET30 0.261 10688190,14690591 Q05785 P39014 ENT2 MET30 0.126 14690591 P39014 P25584 MET30 PEX34 0.126 14690591 P39014 P08539 MET30 GPA1 0.309 15687504 P39014 P0CG63 MET30 UBI4 0.523 11805837,21070969,24648496 P39014 P10591 MET30 SSA1 0.126 19536198 P39014 P00724 MET30 SUC2 0.126 14690591 P39014 P10659 MET30 SAM1 0.126 11805837 P39014 P02557 MET30 TUB2 0.126 11805837 P39014 P12398 MET30 SSC1 0.126 11805837 P39014 P12709 MET30 PGI1 0.126 11805837 P39014 P13382 MET30 POL1 0.126 14690591 P39014 P05085 MET30 ARG81 0.126 14690591 P39014 P07866 MET30 LTE1 0.126 14690591 P39014 P14682 MET30 CDC34 0.236 16554755 Q04533 P39014 Q04533 MET30 0.332 18719252 P47164 P39014 STR2 MET30 0.332 18719252 P39014 P18759 MET30 SEC18 0.332 18719252 P39014 P39014 MET30 MET30 0.416 14660673 P40150 P39014 SSB2 MET30 0.236 23332755,19536198 P39014 P32389 MET30 MET4 0.967 14690591,15883825,10637232,11805837,24389104,15660125,8524217,10975521,21172660,23000173 Q12018 P39014 CDC53 MET30 0.92 9499404,23267104,14690591,24648496,10582239,11805837,19882662,9716410 P52286 P39014 SKP1 MET30 0.998 9499404,22817900,10582239,10637232,20581845,11805837,18719252,12582129,24648496,11283612,19882662,15660125,14660673,21172660,23000173,9716410,10688190,14690591 P39014 P35182 MET30 PTC1 0.126 14690591 P39014 P38085 MET30 TAT1 0.126 14690591 P39014 P38150 MET30 P38150 0.126 14690591 P39014 P38164 MET30 SEA4 0.126 14690591 P39014 P32354 MET30 MCM10 0.126 14690591 P39014 P32367 MET30 TFC1 0.126 14690591 P39014 P38604 MET30 ERG7 0.126 14690591 P39014 P38820 MET30 UBA4 0.126 14690591 P39014 P38855 MET30 PEX18 0.126 14690591 P39014 P32521 MET30 PAN1 0.126 14690591 P39014 A0A0C4DGF1 MET30 ZBTB32 {ECO:0000313|ENSEMBL:ENSP00000433657} 0.332 27107014 P39014 P00950 MET30 GPM1 0.126 11805837 P39014 P02829 MET30 HSP82 0.126 11805837 P39014 P02994 MET30 TEF2 0.126 11805837 P39014 P04806 MET30 HXK1 0.126 11805837 P39014 P09932 MET30 HO 0.21 24389104 P39014 P11484 MET30 SSB1 0.126 19536198 P39014 P16140 MET30 VMA2 0.126 11805837 P39014 P22276 MET30 RET1 0.309 10688190,14690591 P39014 P25294 MET30 SIS1 0.236 11805837 P39014 P25491 MET30 YDJ1 0.126 11805837 P39014 P25694 MET30 CDC48 0.309 11805837,23000173 P39014 P32906 MET30 MNS1 0.396 10688190,14690591 P39014 P35997 MET30 RPS27A 0.126 14690591 P39014 P36008 MET30 TEF4 0.236 11805837 P39014 P38277 MET30 P38277 0.416 10688190,14690591 P39014 P38316 MET30 ATG12 0.126 14690591 P39014 P38346 MET30 BIT2 0.416 10688190,14690591 P39998 P39014 EDC3 MET30 0.396 10688190,14690591 P40364 P39014 MPM1 MET30 0.126 11805837 P47041 P39014 BIT61 MET30 0.396 10688190,14690591 P53919 P39014 NAF1 MET30 0.126 14690591 P61864 P39014 RPL40A MET30 0.21 11805837 Q02159 P39014 UBC7 MET30 0.126 14690591 Q03081 P39014 MET31 MET30 0.21 11805837 Q03919 P39014 RUB1 MET30 0.236 11805837 Q12020 P39014 SRL2 MET30 0.396 10688190,14690591 Q12041 P39014 MET32 MET30 0.21 21172660 P39014 P32805 MET30 FZF1 0.126 14690591 P39014 P32828 MET30 SLX5 0.126 14690591 P39529 P39014 P39529 MET30 0.126 14690591 P39014 P32944 MET30 SWE1 0.033 9716410 P39712 P39014 FLO9 MET30 0.126 14690591 P39720 P39014 OAF1 MET30 0.126 14690591 P39014 P33420 MET30 NIP100 0.126 14690591 P39014 P33757 MET30 SPO23 0.126 14690591 P39014 P36002 MET30 PTK1 0.126 14690591 P43568 P39014 CAK1 MET30 0.126 16554755 P40354 P39014 NTA1 MET30 0.126 14690591 P40588 P39014 P40588 MET30 0.126 14690591 P40439 P39014 IMA3 MET30 0.126 14690591 P40450 P39014 BNR1 MET30 0.126 14690591 P40487 P39014 DPH1 MET30 0.126 14690591 P40505 P39014 SDS3 MET30 0.126 14690591 P40892 P39014 P40892 MET30 0.126 14690591 P39014 P18480 MET30 SNF5 0.126 14690591 P39014 P16522 MET30 CDC23 0.126 14690591 Q06216 P39014 PIG1 MET30 0.126 14690591 P39014 P16649 MET30 TUP1 0.126 14690591 Q06385 P39014 VPS74 MET30 0.126 14690591 P39014 P20484 MET30 MAK11 0.126 14690591 Q03831 P39014 Q03831 MET30 0.261 10688190,14690591 Q07509 P39014 Q07509 MET30 0.126 14690591 P53854 P39014 CWC25 MET30 0.261 10688190,14690591 P53877 P39014 IPI3 MET30 0.21 11283351 Q07738 P39014 Q07738 MET30 0.126 14690591 Q07799 P39014 Q07799 MET30 0.126 14690591 P53900 P39014 GIM3 MET30 0.126 19536198 P53933 P39014 APP1 MET30 0.126 14690591 Q08206 P39014 Q08206 MET30 0.126 14690591 Q05080 P39014 HOF1 MET30 0.126 14690591 P39014 O13550 MET30 O13550 0.126 14690591 Q08273 P39014 HRT1 MET30 0.507 11805837,19882662,24648496 Q08280 P39014 BSC6 MET30 0.126 14690591 Q08446 P39014 SGT1 MET30 0.126 14690591 Q08913 P39014 Q08913 MET30 0.126 14690591 P39014 P22209 MET30 KIN3 0.126 14690591