PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SSE1 PCL7 19536198 intact exp YDJ1 PCL7 19536198 intact exp MGS1 PCL7 11283351 i2d,mint,intact,dip exp PCL7 TYW3 16554755 biogrid,i2d,mint,intact exp PCL7 ORC1 20595233 biogrid exp PCL7 ALY2 12098764 biogrid exp PCL7 PSA1 16429126 intact exp SSA1 PCL7 19536198,23217712 intact exp PCL7 PFD1 19536198 intact exp SSB2 PCL7 23332755,19536198 biogrid,intact exp PCL7 FPR4 11283351 i2d,mint,intact,dip exp CCT3 PCL7 19536198 intact exp PCL7 WHI4 11283351, 23023127 i2d,mint,intact,dip exp, pred PHO81 PCL7 11069666,16611745, 23023127 biogrid,i2d,dip exp, pred PCL7 MTQ2 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PCL7 ATP14 11283351, 23023127 i2d,mint,intact,dip exp, pred SWI4 PCL7 16554755, 23023127 biogrid,i2d,mint,intact exp, pred SSB1 PCL7 19536198, 23023127 biogrid,intact exp, pred PHO85 PCL7 9032248,20489023,16429126,11283351,16611745,18719252,11805837,11069666,10688190, 23023127 biogrid,i2d,mint,intact,dip exp, pred PCL7 MMR1 11283351, 23023127 biogrid,i2d,mint,intact,dip exp, pred CDC28 PCL7 14574415,10688190,17634282,14690591, 23023127 biogrid,i2d,mint,intact,dip exp, pred SHP1 PCL7 23023127 pred PCL7 PCL10 23023127 pred PCL1 PCL7 23023127 pred PCL7 PCL9 23023127 pred CLB1 PCL7 23023127 pred PCL6 PCL7 23023127 pred SWE1 PCL7 23023127 pred PHO80 PCL7 23023127 pred CDC37 PCL7 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P40186 - 11805837 - C 6 Q06324 P40186 - 11283351 - X 2 P17442 P40186 - 11069666 - X 2 P40186 - 11805837 - C 3 P40186 Q07655 - 11283351 - X 2 P17157 P40186 - 11069666 - X 2 P17157 P40186 - 11283351 - X 2 P17157 P40186 - 10688190 - X 2 P17157 P40186 - 9032248 - X 2 Q12349 P40186 - 11283351 - X 2 P40151 P40186 - 11283351 - X 2 Q06205 P40186 - 11283351 - X 2 P00546 P40186 enzymatic study 14574415 direct interaction X 2 P00546 P40186 two hybrid 17634282 direct interaction X 2 P11484 P40186 affinity chromatography technology 19536198 physical association X 2 P11484 P40186 affinity chromatography technology 19536198 physical association X 2 Q06324 P40186 two hybrid 11283351 direct interaction X 2 P17442 P40186 affinity chromatography technology 11069666 physical association X 2 P17442 P40186 two hybrid 11069666 direct interaction X 2 P17442 P40186 affinity chromatography technology 16611745 physical association X 2 P47029 P40186 affinity chromatography technology 12098764 physical association X 2 P53177 P40186 affinity chromatography technology 16554755 physical association X 2 P40150 P40186 biochemical 23332755 association X 2 P25302 P40186 affinity chromatography technology 16554755 physical association X 2 P0CG63 P40186 affinity chromatography technology 23793018 physical association X 2 P17157 P40186 affinity chromatography technology 11069666 physical association X 2 P17157 P40186 pull down 9032248 direct interaction X 2 P17157 P40186 two hybrid 11069666 direct interaction X 2 P17157 P40186 two hybrid 9032248 direct interaction X 2 P17157 P40186 affinity chromatography technology 16611745 physical association X 2 P17157 P40186 affinity chromatography technology 17200106 physical association X 2 P17157 P40186 two hybrid 11283351 direct interaction X 2 P17157 P40186 two hybrid 18719252 direct interaction X 2 P17157 P40186 affinity chromatography technology 20489023 physical association X 2 P17157 P40186 affinity chromatography technology 11805837 physical association X 2 P17157 P40186 two hybrid 11283351 direct interaction X 2 P17157 P40186 two hybrid 10688190 direct interaction X 2 P54784 P40186 affinity chromatography technology 20595233 physical association X 2 Q03920 P40186 affinity chromatography technology 16554755 physical association X 2 P40186 anti tag coimmunoprecipitation 11805837 - C 26 P00546 P40186 two hybrid 10688190 physical association X 2 P00546 P40186 protein kinase assay 14574415 physical association X 2 Q06324 P40186 two hybrid pooling approach 11283351 physical association X 2 P17442 P40186 coimmunoprecipitation 11069666 physical association X 2 P17442 P40186 two hybrid 11069666 physical association X 2 P40186 anti tag coimmunoprecipitation 11805837 - C 7 P40186 Q07655 two hybrid pooling approach 11283351 physical association X 2 P17157 P40186 two hybrid 11069666 physical association X 2 P17157 P40186 biochemical 11069666 physical association X 2 P17157 P40186 affinity chromatography technology 9032248 physical association X 2 P17157 P40186 affinity chromatography technology 11069666 physical association X 2 P17157 P40186 two hybrid pooling approach 11283351 physical association X 2 P17157 P40186 anti tag coimmunoprecipitation 11805837 physical association X 2 P17157 P40186 two hybrid pooling approach 11283351 physical association X 2 P17157 P40186 two hybrid 10688190 physical association X 2 P17157 P40186 two hybrid 9032248 physical association X 2 Q12349 P40186 two hybrid pooling approach 11283351 physical association X 2 P40151 P40186 two hybrid pooling approach 11283351 physical association X 2 Q06205 P40186 two hybrid pooling approach 11283351 physical association X 2 P40186 inferred by author 16554755 association C 3 P40186 anti tag coimmunoprecipitation 11805837 association C 6 P00546 P40186 two hybrid 10688190 physical association X 2 P00546 P40186 two hybrid array 14690591 physical association X 2 P39077 P40186 tandem affinity purification 19536198 association X 2 P11484 P40186 tandem affinity purification 19536198 association X 2 P11484 P40186 tandem affinity purification 19536198 association X 2 Q06324 P40186 two hybrid fragment pooling approach 11283351 physical association X 2 P25491 P40186 tandem affinity purification 19536198 association X 2 P53177 P40186 tandem affinity purification 16554755 physical association X 2 P40150 P40186 tandem affinity purification 19536198 association X 2 P40186 anti tag coimmunoprecipitation 11805837 association C 3 P40186 tandem affinity purification 20489023 association C 13 P40186 tandem affinity purification 16429126 association C 3 P32589 P40186 tandem affinity purification 19536198 association X 2 P25302 P40186 tandem affinity purification 16554755 physical association X 2 P25302 P40186 tandem affinity purification 16554755 physical association X 2 P46988 P40186 tandem affinity purification 19536198 association X 2 P40186 Q07655 two hybrid fragment pooling approach 11283351 physical association X 2 P17157 P40186 two hybrid 10688190 physical association X 2 P17157 P40186 two hybrid fragment pooling approach 11283351 physical association X 2 P17157 P40186 two hybrid fragment pooling approach 11283351 physical association X 2 P17157 P40186 two hybrid 18719252 physical association X 2 P17157 P40186 anti tag coimmunoprecipitation 20489023 association X 2 P17157 P40186 pull down 9032248 physical association X 2 P17157 P40186 two hybrid 9032248 physical association X 2 P10591 P40186 tandem affinity purification 19536198 association X 2 P10591 P40186 two hybrid 23217712 physical association X 2 Q03920 P40186 tandem affinity purification 16554755 physical association X 2 Q12349 P40186 two hybrid fragment pooling approach 11283351 physical association X 2 P40151 P40186 two hybrid fragment pooling approach 11283351 physical association X 2 Q06205 P40186 two hybrid fragment pooling approach 11283351 physical association X 2 P40186 mass spectrometry studies of complexes 11805837 - C 8 Q06324 P40186 two hybrid 11283351 - X 2 P40186 Q07655 two hybrid 11283351 - X 2 P17157 P40186 two hybrid 10688190 - X 2 P17157 P40186 two hybrid 11283351 - X 2 P17157 P40186 two hybrid 9032248 - X 2 P17157 P40186 two hybrid 10688190,9032248 - X 2 P17157 P40186 two hybrid 11283351 - X 2 Q12349 P40186 two hybrid 11283351 - X 2 P40151 P40186 two hybrid 11283351 - X 2 Q06205 P40186 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality CDC28 PCL7 17634282,14574415,14690591,10688190,14574415 0018,0424,0397,0018,0415 HT,LC SSA1 PCL7 23217712 0018 LC PHO85 PCL7 18719252,9032248,9032248,9032248,11283351,11283351,11283351,11069666,11069666,11069666,10688190,10688190 0018,0004,0096,0018,0018,0399,0398,0401,0004,0018,0397,0018 HT,LC PHO81 PCL7 11069666,11069666,11069666 0018,0019,0004 LC SSB2 PCL7 23332755 0401 LC MGS1 PCL7 11283351,11283351,11283351 0018,0399,0398 HT PCL7 FPR4 11283351,11283351,11283351 0018,0399,0398 HT PCL7 MMR1 11283351,11283351,11283351 0018,0399,0398 HT PCL7 WHI4 11283351,11283351,11283351 0018,0399,0398 HT PCL7 ATP14 11283351,11283351,11283351 0018,0399,0398 HT SSA1 PCL7 19536198 0676 HT SSB1 PCL7 19536198,19536198 0004,0676 HT PHO85 PCL7 11805837,9032248,9032248,9032248,16429126,20489023,20489023,20489023,11069666,11069666,11069666,17200106,16611745,11805837 0004,0004,0096,0018,0676,0004,0007,0676,0401,0004,0018,0004,0004,0007 HT,LC PHO81 PCL7 11069666,11069666,16611745,11069666 0018,0019,0004,0004 LC SWI4 PCL7 16554755,16554755 0676,0004 HT YDJ1 PCL7 19536198 0676 HT SSE1 PCL7 19536198 0676 HT CCT3 PCL7 19536198 0676 HT SSB2 PCL7 19536198,23332755 0676,0401 HT,LC PCL7 PSA1 16429126 0676 HT PCL7 PFD1 19536198 0676 HT PCL7 ALY2 12098764 0004 LC PCL7 TYW3 16554755,16554755 0676,0004 HT PCL7 ORC1 20595233 0004 LC PCL7 MTQ2 16554755,16554755,16554755 0363,0676,0004 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q12221 P40186 PUF2 PCL7 0.126 26668354 P40186 P25302 PCL7 SWI4 0.332 16554755 P40186 P25491 PCL7 YDJ1 0.126 19536198 P40186 P00546 PCL7 CDC28 0.523 10688190,14574415,14690591,17634282 P40186 P11484 PCL7 SSB1 0.416 19536198 P40186 P17442 PCL7 PHO81 0.065 11069666 P40186 P10591 PCL7 SSA1 0.286 19536198,23217712 P40186 P17157 PCL7 PHO85 0.895 10688190,16429126,11069666,9032248,11805837,11283351,20489023,18719252 P40186 P32589 PCL7 SSE1 0.126 19536198 P40186 P40150 PCL7 SSB2 0.236 23332755,19536198 P40186 P39077 PCL7 CCT3 0.126 19536198 P40186 P40151 PCL7 MGS1 0.21 11283351 P41940 P40186 PSA1 PCL7 0.126 16429126 P46988 P40186 PFD1 PCL7 0.126 19536198 P47029 P40186 ALY2 PCL7 0.21 12098764 P53177 P40186 TYW3 PCL7 0.236 16554755 Q03920 P40186 MTQ2 PCL7 0.332 16554755 Q06324 P40186 MMR1 PCL7 0.354 11283351 Q07655 P40186 WHI4 PCL7 0.236 11283351 Q12349 P40186 ATP14 PCL7 0.236 11283351 Q06205 P40186 FPR4 PCL7 0.21 11283351 P54784 P40186 ORC1 PCL7 0.126 20595233