PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus NSP1 MLP1 24152732 biogrid exp NSP1 ESC1 24152732 biogrid exp NSP1 UBP8 21734642 biogrid,intact exp NSP1 BUL2 22875988 biogrid exp NSP1 GSP2 i2d exp NSP1 GAS4 16093310 biogrid,dip exp NSP1 MLP2 24500206,24152732 biogrid exp NSP1 GCN5 21734642 intact exp NSP1 MTR4 i2d exp NSP1 YKE2 19536198 intact exp NSP1 RPT5 22875988 biogrid exp NSP1 AIM4 10684247 intact exp NSP1 MRPL3 11805826,16429126 biogrid,mint,intact,dip exp NSP1 PMT1 i2d exp NSP1 GIM3 19536198 i2d,intact exp NSP1 ATG17 11283351 i2d,mint,intact,dip exp HSP82 NSP1 15766533 biogrid,i2d,intact exp NSP1 HLJ1 19536198 intact exp NSP1 RPF2 21926967 biogrid,intact exp SSB1 NSP1 19536198 intact exp NSP1 GIM4 19536198,16554755 biogrid,i2d,mint,intact exp NSP1 SPT20 21734642 intact exp NSP1 SPT8 21734642 intact exp NSP1 CLB2 20489023 biogrid,mint,intact exp NSP1 MRPL1 11805826,16429126 biogrid,mint,intact,dip exp NSP1 HSP26 19536198 intact exp NSP1 MRPL24 11805826,16429126 biogrid,mint,intact,dip exp NSP1 YML6 11805826,16429126 biogrid,mint,intact,dip exp NSP1 LAS17 21035341 biogrid exp NSP1 ARE1 22875988 biogrid exp NSP1 LGE1 21179020 intact exp NSP1 ADA2 21734642 intact exp NSP1 MRPL35 11805826,16429126 biogrid,mint,intact,dip exp NSP1 SMT3 23403034 biogrid exp NSP1 BUB2 21179020 intact exp NSP1 ARX1 18077551 biogrid exp NSP1 HSP78 19536198 intact exp NSP1 PUS1 i2d exp NSP1 MRPL15 11805826,16429126 biogrid,mint,intact,dip exp NSP1 CCT6 18511909 biogrid exp NSP1 MRPL8 11805826,16429126 biogrid,mint,intact,dip exp NSP1 NUP49 24165936,16429126,18467557,11689687,15741174,16554755,22940862,9017593,8227139,7559750,7688296,18046405,9843582, 23023127 biogrid,i2d,mint,intact,dip exp, pred NSP1 YCK1 20489023, 23023127 biogrid,mint,intact exp, pred NSP1 SPC24 21179020, 23023127 intact exp, pred NSP1 DYN2 24165936,17546040, 23023127 biogrid exp, pred NSP1 KAP95 17418788,19098896,22357553,17897934,8849456,9412461, 23023127 biogrid,intact,dip exp, pred NSP1 NUP57 24165936,16429126,18467557,11283351,22940862,10688190,9017593,18046405,11689687,16554755,15741174,22875988,7559750,11387327,7688296,24574455, 23023127 biogrid,i2d,mint,intact,dip exp, pred NSP1 NUP192 18046405, 23023127 biogrid exp, pred NSP1 GLE2 16429126,15741174,18046405, 23023127 biogrid,intact exp, pred NSP1 NUP82 14718168,24165936,16429126,18467557,11689687,11283351,15741174,16554755,18719252,11805826,17546040,7559750,18046405,9843582, 23023127 biogrid,i2d,mint,intact,dip exp, pred NSP1 URB1 15226434, 23023127 biogrid exp, pred NSP1 RRP12 14729571, 23023127 biogrid exp, pred NSP1 NUP53 18046405, 23023127 biogrid exp, pred NSP1 HRR25 20489023, 23023127 biogrid,mint,intact exp, pred NSP1 CRM1 15769879, 23023127 biogrid exp, pred NSP1 GSP1 9199309,9461539, 23023127 biogrid,i2d,dip exp, pred NSP1 NUP133 16554755, 23023127 biogrid,i2d,mint,intact exp, pred NSP1 SEH1 18046405, 23023127 biogrid exp, pred SSA2 NSP1 16429126,19536198, 23023127 biogrid,i2d,intact exp, pred NSP1 SPC72 21179020, 23023127 intact exp, pred NSP1 GLE1 10684247,18046405, 23023127 biogrid,intact exp, pred NSP1 NUP100 18046405, 23023127 biogrid exp, pred NSP1 NIC96 24165936,16429126,18206968,15741174,11805826,22940862,9017593,7559750,7688296,18046405, 23023127 biogrid,i2d,mint,intact,dip exp, pred NSP1 NUP2 18467557, 23023127 biogrid,i2d,mint,intact exp, pred NSP1 ESS1 21179020, 23023127 intact exp, pred NSP1 NSP1 11805826,22940862,19345193, 23023127 biogrid,mint,intact exp, pred NSP1 NAB2 20823268, 23023127 biogrid exp, pred NSP1 MEX67 19401465,17922018,10952996, 23023127 biogrid exp, pred NSP1 NDC1 18046405, 23023127 biogrid exp, pred NSP1 POM152 18046405, 23023127 biogrid exp, pred NSP1 KAP123 12169684,22357553,17897934, 23023127 biogrid exp, pred NSP1 NUP159 24165936,16429126,11689687,15741174,16554755,11805826,17546040,9843582,18046405, 23023127 biogrid,i2d,mint,intact,dip exp, pred NSP1 LOS1 9774653, 23023127 biogrid,i2d,dip exp, pred NSP1 POM34 18046405, 23023127 biogrid exp, pred NSP1 ASM4 18046405, 23023127 biogrid exp, pred NSP1 NUP42 18046405, 23023127 biogrid exp, pred SSA1 NSP1 22940862,19536198, 23023127 biogrid,i2d,intact exp, pred NSP1 NUP1 8227139,18046405, 23023127 biogrid exp, pred NSP1 NTF2 10716708,9368653, 23023127 biogrid,dip exp, pred NSP1 NUP116 11805826,16429126,10684247,10801828,15741174,18046405, 23023127 biogrid,mint,intact,dip exp, pred NSP1 SXM1 9412461, 23023127 biogrid,i2d,intact,dip exp, pred NSP1 MTR2 10952996, 23023127 biogrid exp, pred NSP1 PSE1 9891088,22357553,17897934, 23023127 biogrid,dip exp, pred NSP1 PAC10 19536198,16554755, 23023127 biogrid,i2d,mint,intact exp, pred NSP1 NUP84 19822444,18046405, 23023127 biogrid,i2d exp, pred NSP1 NUP60 18046405, 23023127 biogrid exp, pred NSP1 SAC3 17922018,10716708, 23023127 biogrid,dip exp, pred NSP1 HEK2 18805955, 23023127 biogrid exp, pred NSP1 NUP188 23023127 pred NSP1 NUP145 23023127 pred BIK1 NSP1 23023127 pred NSP1 NUP157 23023127 pred NSP1 RSP5 23023127 pred CDC31 NSP1 23023127 pred NSP1 MTR10 23023127 pred NSP1 SRM1 23023127 pred CMD1 NSP1 23023127 pred RNA1 NSP1 23023127 pred NSP1 YRA1 23023127 pred NSP1 NUP170 23023127 pred NSP1 NUP120 23023127 pred NSP1 KAP104 23023127 pred NSP1 SRP1 23023127 pred NSP1 DYN1 23023127 pred NSP1 NUP85 23023127 pred NSP1 NPL3 23023127 pred NSP1 NPL4 23023127 pred NSP1 YRB1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P14907 - 15766533 - X 2 P02829 P14907 - 15766533 - X 2 P46674 P14907 - 12631707 - X 2 P34077 P14907 - 7688296 - X 2 P32835 P14907 - 9461539 - X 2 P14907 - 11805826 - C 3 P14907 - 11805826 - C 11 P14907 - 11805826 - C 3 P10592 P14907 - 15766533 - X 2 Q04175 P14907 - 9412461 - X 2 P40368 P14907 - 7559750 - X 2 P40368 P14907 - 11283351 - X 2 Q02199 P14907 - 7688296 - X 2 Q02199 P14907 - 9348540 - X 2 P48837 P14907 - 11283351 - X 2 P48837 P14907 - 10688190 - X 2 Q06410 P14907 - 11283351 - X 2 P14907 x-ray crystallography 12581645 association X 2 P14907 pull down 12581645 direct interaction X 2 P33297 P14907 two hybrid 22875988 direct interaction X 2 P39705 P14907 affinity chromatography technology 18046405 physical association X 2 P48363 P14907 affinity chromatography technology 16554755 physical association X 2 Q12445 P14907 affinity chromatography technology 18046405 physical association X 2 P14907 Q03758 two hybrid 22875988 direct interaction X 2 P14907 P40477 affinity chromatography technology 9843582 physical association X 2 P14907 P40477 pull down 11689687 direct interaction X 2 P14907 P40457 affinity chromatography technology 24500206 physical association X 2 P14907 P40477 affinity chromatography technology 16554755 physical association X 2 P14907 P40477 affinity chromatography technology 16429126 physical association X 2 P14907 P40477 affinity chromatography technology 16429126 physical association X 2 P14907 P40477 affinity chromatography technology 15741174 physical association X 2 P14907 P40477 affinity chromatography technology 15741174 physical association X 2 P14907 P40477 affinity chromatography technology 17200106 physical association X 2 P14907 P40477 affinity chromatography technology 17546040 physical association X 2 P14907 P40477 affinity chromatography technology 18046405 physical association X 2 P14907 P40477 affinity chromatography technology 18046405 physical association X 2 P14907 P40477 affinity chromatography technology 11805826 physical association X 2 P24869 P14907 affinity chromatography technology 20489023 physical association X 2 P22353 P14907 affinity chromatography technology 16429126 physical association X 2 P22353 P14907 affinity chromatography technology 11805826 physical association X 2 Q05166 P14907 affinity chromatography technology 18046405 physical association X 2 P33331 P14907 affinity chromatography technology 10716708 physical association X 2 P02829 P14907 two hybrid 15766533 direct interaction X 2 P20676 P14907 biochemical 8227139 colocalization X 2 P39685 P14907 affinity chromatography technology 18046405 physical association X 2 P20676 P14907 affinity chromatography technology 18046405 physical association X 2 P32505 P14907 affinity chromatography technology 20823268 physical association X 2 P23291 P14907 affinity chromatography technology 20489023 physical association X 2 P36523 P14907 affinity chromatography technology 16429126 physical association X 2 P36523 P14907 affinity chromatography technology 11805826 physical association X 2 P34241 P14907 affinity chromatography technology 15226434 physical association X 2 P36160 P14907 affinity chromatography technology 21926967 physical association X 2 P36516 P14907 affinity chromatography technology 16429126 physical association X 2 P36516 P14907 affinity chromatography technology 11805826 physical association X 2 P32500 P14907 affinity chromatography technology 18046405 physical association X 2 Q04599 P14907 affinity chromatography technology 16429126 physical association X 2 Q04599 P14907 affinity chromatography technology 11805826 physical association X 2 P46674 P14907 affinity chromatography technology 10716708 physical association X 2 P46674 P14907 affinity chromatography technology 17922018 physical association X 2 P40069 P14907 affinity chromatography technology 17897934 physical association X 2 P40069 P14907 affinity chromatography technology 12169684 physical association X 2 P40069 P14907 pull down 22357553 direct interaction X 2 P36525 P14907 affinity chromatography technology 16429126 physical association X 2 P36525 P14907 affinity chromatography technology 11805826 physical association X 2 P51998 P14907 affinity chromatography technology 11805826 physical association X 2 P40066 P14907 affinity chromatography technology 16429126 physical association X 2 P40066 P14907 affinity chromatography technology 15741174 physical association X 2 Q12315 P14907 affinity chromatography technology 18046405 physical association X 2 P40066 P14907 affinity chromatography technology 18046405 physical association X 2 P47054 P14907 affinity chromatography technology 18046405 physical association X 2 P47054 P14907 affinity chromatography technology 18046405 physical association X 2 P36161 P14907 affinity chromatography technology 16554755 physical association X 2 P34077 P14907 affinity chromatography technology 22940862 physical association X 2 P34077 P14907 pull down 9017593 direct interaction X 2 P34077 P14907 biochemical 7559750 association X 2 P34077 P14907 biochemical 7688296 association X 2 P34077 P14907 affinity chromatography technology 16429126 physical association X 2 P34077 P14907 affinity chromatography technology 16429126 physical association X 2 P34077 P14907 affinity chromatography technology 15741174 physical association X 2 P34077 P14907 affinity chromatography technology 15741174 physical association X 2 P34077 P14907 affinity chromatography technology 17200106 physical association X 2 P34077 P14907 affinity chromatography technology 18206968 physical association X 2 P34077 P14907 affinity chromatography technology 18046405 physical association X 2 P34077 P14907 affinity chromatography technology 18046405 physical association X 2 P34077 P14907 far western blotting 18046405 direct interaction X 2 P34077 P14907 affinity chromatography technology 11805826 physical association X 2 P32835 P14907 affinity chromatography technology 9199309 physical association X 2 P32835 P14907 pull down 9461539 direct interaction X 2 P34232 P14907 affinity chromatography technology 10952996 physical association X 2 P10592 P14907 affinity chromatography technology 16429126 physical association X 2 Q04175 P14907 affinity chromatography technology 9412461 physical association X 2 P52891 P14907 affinity chromatography technology 19822444 physical association X 2 P52891 P14907 affinity chromatography technology 18046405 physical association X 2 Q12446 P14907 affinity chromatography technology 21035341 physical association X 2 P40368 P14907 affinity chromatography technology 14718168 physical association X 2 P40368 P14907 affinity chromatography technology 7559750 physical association X 2 P40368 P14907 affinity chromatography technology 9843582 physical association X 2 P40368 P14907 pull down 11689687 direct interaction X 2 P40368 P14907 affinity chromatography technology 16554755 physical association X 2 P40368 P14907 affinity chromatography technology 16429126 physical association X 2 P40368 P14907 affinity chromatography technology 16429126 physical association X 2 P40368 P14907 affinity chromatography technology 15741174 physical association X 2 P40368 P14907 affinity chromatography technology 15741174 physical association X 2 P40368 P14907 affinity chromatography technology 17200106 physical association X 2 P40368 P14907 two hybrid 11283351 direct interaction X 2 P40368 P14907 affinity chromatography technology 17546040 physical association X 2 P40368 P14907 protein complementation assay 18467557 direct interaction X 2 P40368 P14907 two hybrid 18719252 direct interaction X 2 P40368 P14907 affinity chromatography technology 18046405 physical association X 2 P40368 P14907 affinity chromatography technology 18046405 physical association X 2 P40368 P14907 far western blotting 18046405 direct interaction X 2 P40368 P14907 affinity chromatography technology 11805826 physical association X 2 P40368 P14907 affinity chromatography technology 11805826 physical association X 2 P14907 P14907 affinity chromatography technology 22940862 physical association X 2 P14907 Q06678 affinity chromatography technology 16429126 physical association X 2 P14907 P14907 pull down 19345193 direct interaction X 2 P14907 Q06678 affinity chromatography technology 11805826 physical association X 2 P53011 P14907 affinity chromatography technology 18046405 physical association X 2 P0CG63 P14907 affinity chromatography technology 23749301 physical association X 2 P0CG63 P14907 affinity chromatography technology 21427232 physical association X 2 P0CG63 P14907 affinity chromatography technology 22213798 physical association X 2 Q08271 P14907 protein complementation assay 16093310 direct interaction X 2 P32499 P14907 protein complementation assay 18467557 direct interaction X 2 P25628 P14907 two hybrid 22875988 direct interaction X 2 Q02630 P14907 affinity chromatography technology 10801828 physical association X 2 Q02630 P14907 biochemical 10684247 association X 2 Q02630 P14907 affinity chromatography technology 16429126 physical association X 2 Q02630 P14907 affinity chromatography technology 15741174 physical association X 2 Q02630 P14907 affinity chromatography technology 15741174 physical association X 2 Q02630 P14907 affinity chromatography technology 17200106 physical association X 2 Q02630 P14907 affinity chromatography technology 18046405 physical association X 2 Q02630 P14907 affinity chromatography technology 11805826 physical association X 2 P50102 P14907 affinity chromatography technology 21734642 physical association X 2 Q12754 P14907 pull down 14729571 direct interaction X 2 Q12306 P14907 protein complementation assay 23403034 direct interaction X 2 P40005 P14907 affinity chromatography technology 16554755 physical association X 2 P33418 P14907 affinity chromatography technology 9774653 physical association X 2 Q02199 P14907 affinity chromatography technology 22940862 physical association X 2 Q02199 P14907 affinity chromatography technology 9843582 physical association X 2 Q02199 P14907 pull down 11689687 direct interaction X 2 Q02199 P14907 pull down 9017593 direct interaction X 2 Q02199 P14907 biochemical 7559750 association X 2 Q02199 P14907 biochemical 7688296 association X 2 Q02199 P14907 biochemical 8227139 colocalization X 2 Q02199 P14907 affinity chromatography technology 16554755 physical association X 2 Q02199 P14907 affinity chromatography technology 15741174 physical association X 2 Q02199 P14907 affinity chromatography technology 15741174 physical association X 2 Q02199 P14907 affinity chromatography technology 17200106 physical association X 2 Q02199 P14907 protein complementation assay 18467557 direct interaction X 2 Q02199 P14907 affinity chromatography technology 18046405 physical association X 2 Q02199 P14907 far western blotting 18046405 direct interaction X 2 Q02199 P14907 affinity chromatography technology 18046405 physical association X 2 P39079 P14907 affinity chromatography technology 18511909 physical association X 2 P49686 P14907 affinity chromatography technology 18046405 physical association X 2 Q02647 P14907 affinity chromatography technology 17546040 physical association X 2 P61971 P14907 unspecified method 10543952 direct interaction X 2 P48837 P14907 affinity chromatography technology 22940862 physical association X 2 P48837 P14907 two hybrid 22875988 direct interaction X 2 P48837 P14907 pull down 11689687 direct interaction X 2 P48837 P14907 pull down 9017593 direct interaction X 2 P48837 P14907 affinity chromatography technology 11387327 physical association X 2 P48837 P14907 biochemical 7559750 association X 2 P48837 P14907 pull down 24574455 direct interaction X 2 P48837 P14907 affinity chromatography technology 16554755 physical association X 2 P48837 P14907 affinity chromatography technology 16429126 physical association X 2 P48837 P14907 affinity chromatography technology 15741174 physical association X 2 P48837 P14907 affinity chromatography technology 15741174 physical association X 2 P48837 P14907 affinity chromatography technology 17200106 physical association X 2 P48837 P14907 two hybrid 11283351 direct interaction X 2 P48837 P14907 protein complementation assay 18467557 direct interaction X 2 P48837 P14907 affinity chromatography technology 18046405 physical association X 2 P48837 P14907 far western blotting 18046405 direct interaction X 2 P48837 P14907 far western blotting 18046405 direct interaction X 2 P48837 P14907 affinity chromatography technology 18046405 physical association X 2 P48837 P14907 two hybrid 11283351 direct interaction X 2 P48837 P14907 two hybrid 10688190 direct interaction X 2 Q06142 P14907 affinity chromatography technology 8849456 physical association X 2 Q06142 P14907 affinity chromatography technology 9412461 physical association X 2 Q06142 P14907 affinity chromatography technology 17897934 physical association X 2 Q06142 P14907 pull down 22357553 direct interaction X 2 Q03862 P14907 pull down 18077551 direct interaction X 2 P29295 P14907 affinity chromatography technology 20489023 physical association X 2 P10591 P14907 affinity chromatography technology 22940862 physical association X 2 Q02629 P14907 affinity chromatography technology 18046405 physical association X 2 Q99257 P14907 affinity chromatography technology 10952996 physical association X 2 Q99257 P14907 fluorescent resonance energy transfer 19401465 direct interaction X 2 Q99257 P14907 affinity chromatography technology 17922018 physical association X 2 Q99257 P14907 pull down 19401465 direct interaction X 2 Q03790 P14907 affinity chromatography technology 18046405 physical association X 2 P30822 P14907 affinity chromatography technology 15769879 physical association X 2 P32337 P14907 affinity chromatography technology 9891088 physical association X 2 P32337 P14907 affinity chromatography technology 17897934 physical association X 2 P32337 P14907 pull down 22357553 direct interaction X 2 P14907 inferred by author 11805826 physical association C 12 P14907 P40477 tandem affinity purification 11805826 physical association X 2 P14907 P40477 affinity chromatography technology 11689687 physical association X 2 P14907 tandem affinity purification 11805826 physical association X 2 P22353 P14907 tandem affinity purification 11805826 physical association X 2 P33331 P14907 two hybrid 9368653 physical association X 2 P36516 P14907 tandem affinity purification 11805826 physical association X 2 Q04599 P14907 tandem affinity purification 11805826 physical association X 2 P46674 P14907 coimmunoprecipitation 10716708 physical association X 2 P36525 P14907 tandem affinity purification 11805826 physical association X 2 P51998 P14907 tandem affinity purification 11805826 physical association X 2 A0A024R6Y2 P14907 far western blotting 19098896 direct interaction X 2 P34077 P14907 coimmunoprecipitation 7688296 physical association X 2 P34077 P14907 tandem affinity purification 11805826 physical association X 2 P32835 P14907 biochemical 9461539 physical association X 2 P32835 P14907 coimmunoprecipitation 9461539 physical association X 2 P32835 P14907 affinity chromatography technology 9461539 physical association X 2 P14907 tandem affinity purification 11805826 - C 3 P14907 tandem affinity purification 11805826 - C 11 P14907 tandem affinity purification 11805826 - C 3 Q04175 P14907 affinity chromatography technology 9412461 physical association X 2 P40368 P14907 tandem affinity purification 11805826 physical association X 2 P40368 P14907 tandem affinity purification 11805826 physical association X 2 P40368 P14907 affinity chromatography technology 11689687 physical association X 2 P40368 P14907 coimmunoprecipitation 7559750 physical association X 2 P40368 P14907 two hybrid pooling approach 11283351 physical association X 2 P14907 Q06678 tandem affinity purification 11805826 physical association X 2 Q08271 P14907 ubiquitin reconstruction 16093310 physical association X 2 Q02630 P14907 tandem affinity purification 11805826 physical association X 2 Q02630 P14907 affinity chromatography technology 10801828 physical association X 2 P33418 P14907 biochemical 9774653 physical association X 2 Q02199 P14907 coimmunoprecipitation 7688296 physical association X 2 P48837 P14907 two hybrid pooling approach 11283351 physical association X 2 P48837 P14907 two hybrid 10688190 physical association X 2 P48837 P14907 two hybrid pooling approach 11283351 physical association X 2 P48837 P14907 affinity chromatography technology 11387327 physical association X 2 P48837 P14907 coimmunoprecipitation 7688296 physical association X 2 P48837 P14907 affinity chromatography technology 11689687 physical association X 2 P48837 P14907 affinity chromatography technology 8565072 physical association X 2 Q06142 P14907 far western blotting 19098896 direct interaction X 2 Q06410 P14907 two hybrid pooling approach 11283351 physical association X 2 P32337 P14907 coimmunoprecipitation 9891088 physical association X 2 P14907 tandem affinity purification 16429126 association C 12 P14907 electron microscopy 10684247 physical association C 26 P14907 tandem affinity purification 21734642 association C 156 P14907 tandem affinity purification 16429126 association C 7 P14907 tandem affinity purification 21926967 association C 202 P14907 tandem affinity purification 21179020 association C 24 P14907 tandem affinity purification 21734642 association C 29 P14907 tandem affinity purification 21734642 association C 66 P14907 tandem affinity purification 21734642 association C 69 P14907 tandem affinity purification 21734642 association C 94 P14907 chromatography technology 10684247 physical association C 57 P14907 tandem affinity purification 21179020 association C 53 P14907 tandem affinity purification 21734642 association C 71 P14907 anti tag coimmunoprecipitation 20489023 association C 10 P14907 tandem affinity purification 21179020 association C 74 P53900 P14907 tandem affinity purification 19536198 association X 2 P48363 P14907 tandem affinity purification 16554755 physical association X 2 P48363 P14907 tandem affinity purification 19536198 association X 2 P48353 P14907 tandem affinity purification 19536198 association X 2 P14907 P40477 tandem affinity purification 16554755 physical association X 2 P14907 P40477 tandem affinity purification 16554755 physical association X 2 P14907 P40477 tandem affinity purification 16554755 physical association X 2 P14907 P40477 tandem affinity purification 16554755 physical association X 2 P14907 P40477 tandem affinity purification 16554755 physical association X 2 P14907 P40477 tandem affinity purification 16554755 physical association X 2 P14907 P40477 tandem affinity purification 16554755 physical association X 2 P11484 P14907 tandem affinity purification 19536198 association X 2 P02829 P14907 two hybrid array 15766533 physical association X 2 P52553 P14907 tandem affinity purification 19536198 association X 2 P36161 P14907 tandem affinity purification 16554755 physical association X 2 P36161 P14907 tandem affinity purification 16554755 physical association X 2 P14907 inferred by author 16429126 physical association C 15 P14907 tandem affinity purification 16429126 association C 5 P14907 tandem affinity purification 14718168 association C 3 P14907 tandem affinity purification 21179020 association C 15 P14907 anti tag coimmunoprecipitation 20489023 association C 35 P14907 anti tag coimmunoprecipitation 20489023 association C 12 P14907 tandem affinity purification 16429126 association C 7 P14907 tandem affinity purification 16429126 association C 7 P14907 tandem affinity purification 21734642 association C 55 P14907 tandem affinity purification 11805826 association C 4 P14907 tandem affinity purification 16429126 association C 3 P14907 tandem affinity purification 21179020 association C 23 P14907 tandem affinity purification 21734642 association C 37 P14907 inferred by author 16554755 association C 4 P14907 tandem affinity purification 16429126 association C 5 P14907 tandem affinity purification 11805826 association C 12 P14907 tandem affinity purification 11805826 association C 12 P14907 tandem affinity purification 16429126 association C 8 P14907 tandem affinity purification 21734642 association C 93 P14907 tandem affinity purification 11805826 association C 4 P14907 tandem affinity purification 16429126 association C 5 P10592 P14907 tandem affinity purification 19536198 association X 2 Q04175 P14907 far western blotting 9412461 physical association X 2 P40368 P14907 two hybrid fragment pooling approach 11283351 physical association X 2 P40368 P14907 tandem affinity purification 16554755 physical association X 2 P40368 P14907 tandem affinity purification 16554755 physical association X 2 P40368 P14907 tandem affinity purification 16554755 physical association X 2 P40368 P14907 tandem affinity purification 16554755 physical association X 2 P40368 P14907 dihydrofolate reductase reconstruction 18467557 physical association X 2 P40368 P14907 two hybrid 18719252 physical association X 2 P14907 P15992 tandem affinity purification 19536198 association X 2 P32499 P14907 dihydrofolate reductase reconstruction 18467557 physical association X 2 P33416 P14907 tandem affinity purification 19536198 association X 2 P40005 P14907 tandem affinity purification 16554755 physical association X 2 P40005 P14907 tandem affinity purification 19536198 association X 2 Q02199 P14907 tandem affinity purification 16554755 physical association X 2 Q02199 P14907 dihydrofolate reductase reconstruction 18467557 physical association X 2 P48837 P14907 two hybrid 10688190 physical association X 2 P48837 P14907 two hybrid fragment pooling approach 11283351 physical association X 2 P48837 P14907 two hybrid fragment pooling approach 11283351 physical association X 2 P48837 P14907 tandem affinity purification 16554755 physical association X 2 P48837 P14907 tandem affinity purification 16554755 physical association X 2 P48837 P14907 tandem affinity purification 16554755 physical association X 2 P48837 P14907 tandem affinity purification 16554755 physical association X 2 P48837 P14907 tandem affinity purification 16554755 physical association X 2 P48837 P14907 tandem affinity purification 16554755 physical association X 2 P48837 P14907 dihydrofolate reductase reconstruction 18467557 physical association X 2 Q14974 P14907 x-ray crystallography 12372823 direct interaction X 2 Q14974 P14907 competition binding 19680228 direct interaction X 2 Q06142 P14907 pull down 17418788 direct interaction X 2 Q06142 P14907 pull down 17418788 direct interaction X 2 Q06142 P14907 far western blotting 9412461 physical association X 2 P10591 P14907 tandem affinity purification 19536198 association X 2 Q06410 P14907 two hybrid fragment pooling approach 11283351 physical association X 2 P14907 P14907 confirmational text mining - - Y 1 P34077 P14907 coimmunoprecipitation - - X 2 P34077 P14907 coimmunoprecipitation 7688296 - X 2 P32835 P14907 affinity chromatography technology 9461539 - X 2 P14907 confirmational text mining - - C 4 P14907 mass spectrometry studies of complexes 11805826 - C 3 P52891 P14907 interaction detection method 9822591 - X 2 Q04175 P14907 coimmunoprecipitation 9412461 - X 2 P40368 P14907 interaction detection method 7559750 - X 2 P40368 P14907 two hybrid 11283351 - X 2 P40368 P14907 confirmational text mining - - X 2 Q12211 P14907 interaction detection method - - X 2 P33418 P14907 interaction detection method - - X 2 Q02199 P14907 coimmunoprecipitation 7688296 - X 2 Q02199 P14907 coimmunoprecipitation 7688296,9348540 - X 2 P48837 P14907 two hybrid 11283351 - X 2 P48837 P14907 two hybrid 10688190 - X 2 P48837 P14907 two hybrid 10688190,7688296 - X 2 P48837 P14907 two hybrid 11283351 - X 2 Q06410 P14907 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality HSP82 NSP1 15766533,15766533 0397,0018 LC NSP1 NUP1 8227139 0401 LC NSP1 ARE1 22875988 0018 HT NSP1 PSE1 9891088,9891088 0004,0019 LC NSP1 NUP2 18467557,18467557 0090,0111 HT NSP1 GSP1 9461539,9461539,9461539,9461539 0004,0401,0019,0096 LC NSP1 RPT5 22875988 0018 HT NSP1 NTF2 9368653 0018 LC NSP1 LOS1 9774653,9774653 0004,0401 LC NSP1 NIC96 7688296,7688296,7559750,18046405,18046405 0401,0019,0401,0047,0004 LC NSP1 AIM4 10684247 0091 LC NSP1 NUP82 18467557,18046405,27194810,11283351,11283351,18046405,7559750,18719252,11283351,18467557,7559750 0111,0004,0397,0398,0399,0047,0019,0018,0018,0090,0004 HT,LC NSP1 SAC3 10716708,10716708 0019,0004 LC NSP1 NUP57 18467557,7559750,18046405,27194810,11283351,7688296,10688190,11283351,18046405,7688296,22875988,11283351,18467557,10688190 0111,0401,0004,0397,0398,0019,0397,0399,0047,0018,0018,0018,0090,0018 HT,LC NSP1 NUP49 18467557,7559750,18046405,7688296,18046405,9348540,18467557,7688296,8227139 0111,0401,0004,0019,0047,0019,0090,0401,0401 HT,LC NSP1 NUP116 10684247 0401 LC NSP1 BUL2 22875988 0018 HT NSP1 SXM1 9412461,9412461,9412461 0047,0019,0004 LC NSP1 ASM4 27194810 0397 LC NSP1 KAP95 9412461,9412461,19098896 0004,0047,0047 LC NSP1 ATG17 11283351,11283351,11283351 0018,0399,0398 HT NSP1 GAS4 16093310,16093310 0090,0112 HT NSP1 SMT3 23403034 0090 HT NSP1 GLE1 10684247 0040 LC NSP1 MEX67 19401465,19401465 0055,0096 LC UBI4 NSP1 22213798 0004 LC SSA1 NSP1 22940862,19536198 0004,0676 HT SSA2 NSP1 19536198,16429126,15766533,16429126 0676,0676,0004,0004 HT,LC SSB1 NSP1 19536198 0676 HT NSP1 NSP1 22940862,11805826,11805826,19345193 0004,0676,0007,0096 HT,LC NSP1 HSP26 19536198 0676 HT NSP1 NUP1 18046405,8227139 0004,0401 LC NSP1 MRPL8 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT NSP1 ESS1 21179020 0676 HT NSP1 YCK1 20489023,20489023 0007,0004 HT NSP1 CLB2 20489023,20489023 0007,0004 HT NSP1 BUB2 21179020 0676 HT NSP1 HRR25 20489023,20489023 0007,0004 HT NSP1 CRM1 15769879 0004 LC NSP1 PSE1 9891088,17897934,9891088,22357553 0004,0004,0019,0096 LC NSP1 NDC1 18046405 0004 LC NSP1 NAB2 20823268 0004 LC NSP1 GSP1 9461539,9461539,9461539,9461539,9199309 0004,0401,0019,0096,0004 LC NSP1 NTF2 10716708 0004 LC NSP1 HSP78 19536198 0676 HT NSP1 LOS1 9774653,9774653 0004,0401 LC NSP1 NIC96 11805826,15741174,22940862,9017593,16429126,7688296,24165936,11805826,7688296,7559750,11805826,17200106,18206968,16429126,18046405,18046405 0007,0004,0004,0096,0676,0401,0004,0676,0019,0401,0004,0004,0004,0004,0047,0004 HT,LC NSP1 MTR2 10952996 0004 LC NSP1 URB1 15226434 0004 LC NSP1 RPF2 21926967,21926967 0004,0676 LC NSP1 NUP133 16554755,16554755,16554755 0363,0676,0004 HT NSP1 MRPL3 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT NSP1 MRPL15 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT NSP1 MRPL24 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT NSP1 SPT8 21734642 0676 LC NSP1 CCT6 18511909 0004 LC NSP1 POM152 18046405 0004 LC NSP1 NUP60 18046405 0004 LC NSP1 SPC72 21179020 0676 HT NSP1 GIM4 19536198,16554755,16554755 0676,0676,0004 HT NSP1 GLE2 18046405,16429126,15741174,16429126,16429126 0004,0676,0004,0004,0363 LC,HT NSP1 KAP123 17897934,12169684,22357553 0004,0004,0096 LC NSP1 NUP82 14718168,9843582,17200106,18046405,17546040,18046405,16554755,16554755,15741174,16429126,11805826,7559750,14718168,16554755,16429126,24165936,11805826,7559750,11689687,11805826,11689687 0676,0004,0004,0004,0004,0047,0363,0676,0004,0676,0004,0019,0004,0004,0004,0004,0676,0004,0096,0007,0004 LC,HT NSP1 MLP2 24500206,24152732 0004,0004 LC NSP1 NUP159 11689687,9843582,16554755,16554755,15741174,16429126,17546040,11805826,24165936,11805826,16554755,11689687,17200106,11805826,16429126,18046405 0004,0004,0363,0676,0004,0004,0004,0004,0004,0676,0004,0096,0004,0007,0676,0004 LC,HT NSP1 SAC3 17922018,10716708,10716708 0004,0019,0004 LC NSP1 NUP192 18046405 0004 LC NSP1 HLJ1 19536198 0676 HT NSP1 PAC10 19536198,16554755,16554755 0676,0676,0004 HT NSP1 NUP57 8565072,7559750,17200106,18046405,22940862,18046405,16554755,15741174,16429126,9017593,11387327,11689687,24574455,16554755,16429126,24165936,11689687 0004,0401,0004,0004,0004,0047,0676,0004,0676,0096,0004,0004,0096,0004,0004,0004,0096 LC,HT NSP1 NUP42 18046405 0004 LC NSP1 UBP8 21734642,21734642 0676,0004 LC NSP1 SPT20 21734642 0676 LC NSP1 YML6 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT NSP1 YKE2 19536198 0676 HT NSP1 NUP84 19822444,18046405 0004,0004 LC NSP1 SEH1 18046405 0004 LC NSP1 GIM3 19536198 0676 HT NSP1 NUP49 9843582,24165936,7559750,17200106,18046405,22940862,7688296,18046405,16554755,15741174,16429126,9017593,16554755,7688296,11689687,8227139 0004,0004,0401,0004,0004,0004,0019,0047,0676,0004,0676,0096,0004,0401,0096,0401 LC,HT NSP1 ADA2 21734642 0676 LC NSP1 MLP1 24152732 0004 LC NSP1 NUP100 18046405 0004 LC NSP1 NUP116 11805826,15741174,16429126,11805826,10801828,11805826,10684247,17200106,18046405,16429126 0007,0004,0676,0004,0004,0676,0401,0004,0004,0004 HT,LC NSP1 DYN2 17546040,24165936 0004,0004 LC NSP1 LGE1 21179020 0676 HT NSP1 GCN5 21734642 0676 LC NSP1 ESC1 24152732 0004 LC NSP1 NUP53 18046405 0004 LC NSP1 ARX1 18077551 0096 LC NSP1 SXM1 9412461,9412461,9412461 0047,0019,0004 LC NSP1 SPC24 21179020 0676 HT NSP1 MRPL1 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT NSP1 ASM4 18046405 0004 LC NSP1 KAP95 17897934,9412461,22357553,8849456,17418788,9412461 0004,0004,0096,0004,0096,0047 LC NSP1 MRPL35 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT NSP1 GLE1 18046405 0004 LC NSP1 POM34 18046405 0004 LC NSP1 LAS17 21035341 0004 LC NSP1 RRP12 14729571 0096 LC NSP1 MEX67 10952996,17922018,19401465,19401465 0004,0004,0055,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q04477 P14907 SPC24 NSP1 0.126 21179020 P22696 P14907 ESS1 NSP1 0.126 21179020 P23291 P14907 YCK1 NSP1 0.286 20489023 P61971 P14907 NUTF2 NSP1 0.309 10543952 Q12221 P14907 PUF2 NSP1 0.126 26668354 Q12306 P14907 SMT3 NSP1 0.183 23403034 Q12315 P14907 GLE1 NSP1 0.126 10684247 Q12445 P14907 POM34 NSP1 0.126 18046405 Q12446 P14907 LAS17 NSP1 0.126 21035341 P14907 P10592 NSP1 SSA2 0.236 16429126,19536198 P14907 P14907 NSP1 NSP1 0.436 11805826,19345193 P34077 P14907 NIC96 NSP1 0.681 11805826,16429126,7688296,18206968,24165936 P40477 P14907 NUP159 NSP1 0.78 11805826,11689687,16429126,24165936,16554755,18046405,15741174 Q14974 P14907 KPNB1 NSP1 0.523 19680228,12372823 Q9UBU9 P14907 NXF1 NSP1 0.523 12581645 Q02630 P14907 NUP116 NSP1 0.309 11805826,10801828,16429126 P36160 P14907 RPF2 NSP1 0.236 21926967 P40069 P14907 KAP123 NSP1 0.569 12169684,17897934,22357553 P32835 P14907 GSP1 NSP1 0.096 9461539 Q8IYF3 P14907 TEX11 NSP1 0.332 27107014 Q99257 P14907 MEX67 NSP1 0.583 17922018,19401465 P40066 P14907 GLE2 NSP1 0.472 16429126,18046405,15741174 P40368 P14907 NUP82 NSP1 0.943 11689687,27194810,18467557,24165936,16554755,11283351,15741174,18719252,11805826,7559750,16429126 P48837 P14907 NUP57 NSP1 0.922 10688190,11689687,27194810,18467557,7688296,16554755,8565072,11387327,18046405,24574455,16429126,24165936,11283351 P38199 P14907 HEK2 NSP1 0.126 18805955 P38305 P14907 AIM4 NSP1 0.126 10684247 P26448 P14907 BUB2 NSP1 0.126 21179020 P32337 P14907 PSE1 NSP1 0.569 9891088,17897934,22357553 P32499 P14907 NUP2 NSP1 0.286 18467557 P32505 P14907 NAB2 NSP1 0.21 20823268 P38915 P14907 SPT8 NSP1 0.126 21734642 P39079 P14907 CCT6 NSP1 0.126 18511909 P39685 P14907 POM152 NSP1 0.126 18046405 P39705 P14907 NUP60 NSP1 0.126 18046405 P39723 P14907 SPC72 NSP1 0.126 21179020 P36525 P14907 MRPL24 NSP1 0.332 11805826,16429126 P33418 P14907 LOS1 NSP1 0.033 9774653 P40457 P14907 MLP2 NSP1 0.126 24152732 P46674 P14907 SAC3 NSP1 0.155 10716708,17922018 P47054 P14907 NUP192 NSP1 0.126 18046405 P48353 P14907 HLJ1 NSP1 0.126 19536198 P48363 P14907 PAC10 NSP1 0.332 16554755,19536198 P49686 P14907 NUP42 NSP1 0.126 18046405 P50102 P14907 UBP8 NSP1 0.126 21734642 P50875 P14907 SPT20 NSP1 0.126 21734642 P14907 P11484 NSP1 SSB1 0.126 19536198 P14907 P10591 NSP1 SSA1 0.126 19536198 P14907 P02829 NSP1 HSP82 0.286 15766533 P40005 P14907 GIM4 NSP1 0.332 16554755,19536198 P22353 P14907 MRPL8 NSP1 0.286 11805826,16429126 P15992 P14907 HSP26 NSP1 0.126 19536198 P20676 P14907 NUP1 NSP1 0.126 8227139 P24869 P14907 CLB2 NSP1 0.332 20489023 P29295 P14907 HRR25 NSP1 0.332 20489023 P36523 P14907 MRPL15 NSP1 0.286 11805826,16429126 P33416 P14907 HSP78 NSP1 0.126 19536198 P33331 P14907 NTF2 NSP1 0.033 9368653 P36516 P14907 MRPL3 NSP1 0.286 11805826,16429126 P36161 P14907 NUP133 NSP1 0.332 16554755 P52553 P14907 YKE2 NSP1 0.126 19536198 P51998 P14907 YML6 NSP1 0.286 11805826,16429126 Q04175 P14907 SXM1 NSP1 0.033 9412461 Q02647 P14907 DYN2 NSP1 0.21 24165936 Q04599 P14907 MRPL1 NSP1 0.286 11805826,16429126 Q05166 P14907 ASM4 NSP1 0.236 18046405,27194810 Q06410 P14907 ATG17 NSP1 0.236 11283351 Q06678 P14907 MRPL35 NSP1 0.286 11805826,16429126 Q02199 P14907 NUP49 NSP1 0.692 18467557,16429126,7688296,8227139,24165936,16554755,18046405 Q02336 P14907 ADA2 NSP1 0.126 21734642 Q02455 P14907 MLP1 NSP1 0.126 24152732 Q06142 P14907 KAP95 NSP1 0.636 17897934,22357553,17418788 Q03661 P14907 ESC1 NSP1 0.126 24152732 Q02796 P14907 LGE1 NSP1 0.126 21179020 Q03330 P14907 GCN5 NSP1 0.126 21734642 Q03790 P14907 NUP53 NSP1 0.126 18046405 Q03862 P14907 ARX1 NSP1 0.309 18077551 P53900 P14907 GIM3 NSP1 0.126 19536198 P52891 P14907 NUP84 NSP1 0.21 19822444 Q08271 P14907 GAS4 NSP1 0.183 16093310 P53011 P14907 SEH1 NSP1 0.126 18046405