PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus UBP12 UBP3 i2d exp UBP12 GIS2 21232131 biogrid exp UBP12 YPQ1 i2d exp UBP12 PFK26 17559233 intact exp UBP12 BUL2 i2d exp SSB1 UBP12 16429126,19536198 intact exp ZUO1 UBP12 19536198 intact exp CCT3 UBP12 19536198 intact exp CAJ1 UBP12 19536198 intact exp UBP12 CSF1 i2d exp BNA4 UBP12 i2d exp SIS1 UBP12 19536198 intact exp GPA1 UBP12 15519996 biogrid exp UBP12 ALY2 i2d exp UBP12 Uncharacterized protein YOR019W i2d exp SSA1 UBP12 16429126,19536198 intact exp UBP12 ATG1 24440502 biogrid exp HSP78 UBP12 19536198 intact exp SSE1 UBP12 19536198 intact exp PWP2 UBP12 i2d exp UBP12 SAC3 17922018 biogrid exp UBP12 UBP8 21734642 intact exp SSA2 UBP12 19536198 intact exp FZO1 UBP12 23317502 biogrid exp UBP12 GPG1 i2d exp MAK31 UBP12 i2d exp UBP12 Uncharacterized protein YOL159C i2d exp UBP12 JJJ2 19536198 intact exp UBP12 JEM1 19536198 intact exp UBP12 ERJ5 19536198 intact exp UBP12 PDS1 22072716 biogrid exp UBP12 SPP382 14690591 intact exp UBP12 PUF3 26493364 biogrid exp UBP12 GCN5 21734642 biogrid,intact exp UBP12 FKH1 11805837, 23023127 biogrid,mint,intact,dip exp, pred UBP12 GEA1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P39538 - 11805837 - C 27 P39538 Q12306 protein complementation assay 23403034 direct interaction X 2 P40316 P39538 enzymatic study 22072716 direct interaction X 2 P46674 P39538 affinity chromatography technology 17922018 physical association X 2 P39538 W4YHN9 enzymatic study 22072716 direct interaction X 2 P0CG63 P39538 affinity chromatography technology 23793018 physical association X 2 P47102 P39538 affinity chromatography technology 16554755 physical association X 2 P08539 P39538 affinity chromatography technology 15519996 physical association X 2 Q03330 P39538 affinity chromatography technology 21734642 physical association X 2 P40466 P39538 affinity chromatography technology 11805837 physical association X 2 P38297 P39538 affinity chromatography technology 23317502 physical association X 2 P39538 anti tag coimmunoprecipitation 11805837 - C 27 P39538 anti tag coimmunoprecipitation 11805837 - C 32 P40466 P39538 anti tag coimmunoprecipitation 11805837 physical association X 2 P39538 anti tag coimmunoprecipitation 17559233 association C 270 P39538 tandem affinity purification 21734642 association C 157 P39538 tandem affinity purification 21734642 association C 100 P39538 anti tag coimmunoprecipitation 11805837 association C 27 P39538 tandem affinity purification 21734642 association C 66 P32589 P39538 tandem affinity purification 19536198 association X 2 P25294 P39538 tandem affinity purification 19536198 association X 2 P39538 P32527 tandem affinity purification 19536198 association X 2 P39538 P33416 tandem affinity purification 19536198 association X 2 P10591 P39538 tandem affinity purification 19536198 association X 2 P39538 tandem affinity purification 16429126 association C 3 P10592 P39538 tandem affinity purification 19536198 association X 2 P39077 P39538 tandem affinity purification 19536198 association X 2 P11484 P39538 tandem affinity purification 19536198 association X 2 P39101 P39538 tandem affinity purification 19536198 association X 2 P40358 P39538 tandem affinity purification 19536198 association X 2 Q06411 P39538 two hybrid array 14690591 physical association X 2 P47102 P39538 inferred by author 16554755 association X 2 P47102 P39538 tandem affinity purification 16554755 physical association X 2 P46997 P39538 tandem affinity purification 19536198 association X 2 P43613 P39538 tandem affinity purification 19536198 association X 2 P39538 mass spectrometry studies of complexes 11805837 - C 28

PPI - HINT Gene A Gene B PMID Method Quality UBP12 PDS1 22072716 0415 LC UBP12 ATG1 24440502 0415 LC UBP12 SPP382 14690591 0397 LC GPA1 UBP12 15519996 0004 LC SSA1 UBP12 19536198,16429126 0676,0676 HT SSA2 UBP12 19536198 0676 HT SSB1 UBP12 19536198,16429126 0676,0676 HT SIS1 UBP12 19536198 0676 HT ZUO1 UBP12 19536198 0676 HT SSE1 UBP12 19536198 0676 HT HSP78 UBP12 19536198 0676 HT FZO1 UBP12 23317502 0004 LC CCT3 UBP12 19536198 0676 HT CAJ1 UBP12 19536198 0676 HT UBP12 JEM1 19536198 0676 HT UBP12 PFK26 17559233 0007 LC UBP12 FKH1 11805837,11805837 0004,0007 HT UBP12 ERJ5 19536198 0676 HT UBP12 SAC3 17922018 0004 LC UBP12 JJJ2 19536198 0676 HT UBP12 GEA1 16554755,16554755,16554755 0363,0676,0004 HT UBP12 UBP8 21734642 0676 LC UBP12 GCN5 21734642,21734642 0676,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53104 P39538 ATG1 UBP12 0.309 24440502 P39538 P25294 UBP12 SIS1 0.126 19536198 P39538 P10592 UBP12 SSA2 0.126 19536198 Q03330 P39538 GCN5 UBP12 0.236 21734642 P39538 P32527 UBP12 ZUO1 0.126 19536198 P39538 P08539 UBP12 GPA1 0.21 15519996 P39538 P10591 UBP12 SSA1 0.236 16429126,19536198 P39538 P11484 UBP12 SSB1 0.236 16429126,19536198 P39538 P32589 UBP12 SSE1 0.126 19536198 P39538 P38297 UBP12 FZO1 0.21 23317502 P39538 P39077 UBP12 CCT3 0.126 19536198 P39538 P39101 UBP12 CAJ1 0.126 19536198 P40316 P39538 PDS1 UBP12 0.309 22072716 P47102 P39538 GEA1 UBP12 0.236 16554755 Q06411 P39538 SPP382 UBP12 0.126 14690591 P39538 P33416 UBP12 HSP78 0.126 19536198 P40358 P39538 JEM1 UBP12 0.126 19536198 P40433 P39538 PFK26 UBP12 0.126 17559233 P43613 P39538 ERJ5 UBP12 0.126 19536198 P40466 P39538 FKH1 UBP12 0.21 11805837 P46674 P39538 SAC3 UBP12 0.126 17922018 P46997 P39538 JJJ2 UBP12 0.126 19536198 P50102 P39538 UBP8 UBP12 0.126 21734642 P53849 P39538 GIS2 UBP12 0.126 21232131