PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RCY1 CDC53 14747994 biogrid exp YPT31 RCY1 15537705 biogrid exp RCY1 SKP1 11283612,23535662,23000173,16432255,19882662,21686101,14747994,11287615 biogrid,i2d,intact,dip exp RCY1 HRT1 14747994 biogrid exp YDJ1 RCY1 19536198 intact exp RCY1 RPN6 i2d exp POL30 RCY1 i2d exp RCY1 HHT1, HHT2 22199229 biogrid exp SSA1 RCY1 19536198 intact exp HSP82 RCY1 19536198 intact exp SSB1 RCY1 19536198 intact exp RCY1 ECM10 19536198 intact exp RCY1 YPT32 15537705 biogrid exp SSZ1 RCY1 19536198 intact exp HSP104 RCY1 19536198 intact exp RCY1 DJP1 19536198 intact exp RCY1 RCY1 14747994 biogrid exp SSE1 RCY1 19536198 intact exp RCY1 DNF2 17093059, 23023127 biogrid exp, pred DNF1 RCY1 17093059, 23023127 biogrid exp, pred CDC50 RCY1 17093059, 23023127 biogrid exp, pred SNC1 RCY1 21686101,15537705, 23023127 biogrid exp, pred DRS2 RCY1 17093059,24272750, 23023127 biogrid exp, pred PEP7 RCY1 23023127 pred PEP3 RCY1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P52286 P39531 - 11283612 - X 2 P39531 Q12018 pull down 14747994 direct interaction X 2 P39531 P38555 affinity chromatography technology 15537705 physical association X 2 P39531 P38555 two hybrid 15537705 direct interaction X 2 P39531 P31109 affinity chromatography technology 15537705 physical association X 2 P39531 P39531 enzymatic study 14747994 direct interaction X 2 P39531 P39524 two hybrid 24272750 direct interaction X 2 P39531 P39524 pull down 24272750 direct interaction X 2 P39531 P39524 two hybrid 24272750 direct interaction X 2 P39531 P39524 affinity chromatography technology 24272750 physical association X 2 P39531 P39524 affinity chromatography technology 17093059 physical association X 2 P39531 Q12675 affinity chromatography technology 17093059 physical association X 2 P39531 P31109 affinity chromatography technology 21686101 physical association X 2 P39531 P31109 protein complementation assay 21686101 direct interaction X 2 P39531 P61830 affinity chromatography technology 22199229 physical association X 2 P39531 P61830 affinity chromatography technology 22199229 physical association X 2 P52286 P39531 pull down 23000173 direct interaction X 2 P52286 P39531 affinity chromatography technology 11287615 physical association X 2 P52286 P39531 affinity chromatography technology 11283612 physical association X 2 P52286 P39531 two hybrid 11287615 direct interaction X 2 P52286 P39531 two hybrid 11287615 direct interaction X 2 P52286 P39531 pull down 14747994 direct interaction X 2 P52286 P39531 affinity chromatography technology 23535662 physical association X 2 P52286 P39531 affinity chromatography technology 16432255 physical association X 2 P52286 P39531 affinity chromatography technology 21686101 physical association X 2 P52286 P39531 protein complementation assay 21686101 direct interaction X 2 Q08273 P39531 pull down 14747994 direct interaction X 2 P0CG63 P39531 affinity chromatography technology 12872131 physical association X 2 P39531 P51996 two hybrid 15537705 direct interaction X 2 P39531 P51996 two hybrid 15537705 direct interaction X 2 P39531 P25656 affinity chromatography technology 17093059 physical association X 2 P32660 P39531 affinity chromatography technology 17093059 physical association X 2 P52286 P39531 affinity chromatography technology 14747994 physical association X 2 P52286 P39531 coimmunoprecipitation 11287615 physical association X 2 P52286 P39531 coimmunoprecipitation 11283612 physical association X 2 P52286 P39531 two hybrid 11287615 physical association X 2 P39531 affinity chromatography technology 14747994 - C 4 P39531 anti tag coimmunoprecipitation 11283612 association C 12 P32589 P39531 tandem affinity purification 19536198 association X 2 P39531 P39987 tandem affinity purification 19536198 association X 2 P39531 P02829 tandem affinity purification 19536198 association X 2 P39531 pull down 19882662 association C 51 P11484 P39531 tandem affinity purification 19536198 association X 2 P39531 P40564 tandem affinity purification 19536198 association X 2 P39531 P25491 tandem affinity purification 19536198 association X 2 P39531 P38788 tandem affinity purification 19536198 association X 2 P39531 P31539 tandem affinity purification 19536198 association X 2 P10591 P39531 tandem affinity purification 19536198 association X 2

PPI - HINT Gene A Gene B PMID Method Quality SNC1 RCY1 21686101,21686101 0004,0090 LC YPT31 RCY1 15537705,15537705 0004,0018 LC DRS2 RCY1 24272750,24272750,24272750 0004,0018,0096 LC RCY1 RCY1 14747994 0415 LC RCY1 YPT32 15537705 0018 LC RCY1 SKP1 11287615,11287615,21686101,11283612,11283612,21686101,11283612,11287615 0018,0019,0090,0019,0004,0004,0007,0004 LC HSP82 RCY1 19536198 0676 HT SSA1 RCY1 19536198 0676 HT SSB1 RCY1 19536198 0676 HT YDJ1 RCY1 19536198 0676 HT CDC50 RCY1 17093059 0004 LC SNC1 RCY1 21686101,15537705,21686101 0004,0004,0090 LC HSP104 RCY1 19536198 0676 HT SSE1 RCY1 19536198 0676 HT DNF1 RCY1 17093059 0004 LC YPT31 RCY1 15537705,15537705 0004,0018 LC SSZ1 RCY1 19536198 0676 HT DRS2 RCY1 24272750,24272750,17093059,24272750 0004,0018,0004,0096 LC RCY1 ECM10 19536198 0676 HT RCY1 DJP1 19536198 0676 HT RCY1 SKP1 11287615,11287615,14747994,21686101,19882662,23000173,11283612,11283612,21686101,11283612,14747994,16432255,11287615,23535662 0018,0019,0004,0090,0096,0096,0019,0004,0004,0007,0096,0004,0004,0004 LC RCY1 HHT1|HHT2 22199229 0004 HT RCY1 HRT1 14747994 0096 LC RCY1 CDC53 14747994 0096 LC RCY1 DNF2 17093059 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q12018 P39531 CDC53 RCY1 0.309 14747994 P39531 P25491 RCY1 YDJ1 0.126 19536198 P39531 P10591 RCY1 SSA1 0.126 19536198 P39531 P39524 RCY1 DRS2 0.74 24272750 P52286 P39531 SKP1 RCY1 0.794 11283612,21686101,19882662,14747994,11287615,23535662,23000173 P39531 P38555 RCY1 YPT31 0.454 15537705 P39531 P31109 RCY1 SNC1 0.569 21686101,15537705 P39531 P31539 RCY1 HSP104 0.126 19536198 P39531 P38788 RCY1 SSZ1 0.126 19536198 P39531 P32589 RCY1 SSE1 0.126 19536198 P39531 P02829 RCY1 HSP82 0.126 19536198 P39531 P11484 RCY1 SSB1 0.126 19536198 P39531 P36012 RCY1 CSE4 0.376 26975376 P39531 P39531 RCY1 RCY1 0.332 14747994 P39987 P39531 ECM10 RCY1 0.126 19536198 P51996 P39531 YPT32 RCY1 0.523 15537705 P40564 P39531 DJP1 RCY1 0.126 19536198