PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus GRR1 CCT3 18511909 biogrid exp GRR1 NDD1 25894965 biogrid exp CLN3 GRR1 22844257 biogrid exp GRR1 Uncharacterized protein YIR016W 23144720 biogrid exp GRR1 STP2 21127045 biogrid exp GRR1 CCT8 19536198 intact exp GRR1 DSE3 23144720 biogrid exp PGI1 GRR1 11805837 dip exp GRR1 SBE2 24389104 biogrid exp GRR1 PDC6 11805837 biogrid,intact,dip exp UBI4 GRR1 11805837 biogrid exp GRR1 SAH1 11805837 biogrid,intact,dip exp GRR1 FOL2 11805837 biogrid,intact,dip exp HTB2 GRR1 11805837 biogrid,intact,dip exp FOB1 GRR1 23144720 biogrid exp GRR1 PRO3 i2d exp RPL40A GRR1 11805837 intact,dip exp GRR1 CAK1 16554755 intact exp GRR1 THI20 11805837 dip exp GRR1 GIS4 15890364 biogrid exp GRR1 RVS167 19841731 mint,intact exp GRR1 FIR1 24389104 biogrid exp GRR1 PRP3 23144720 biogrid exp GRR1 MTH1 24389104,15456873 biogrid exp GRR1 ELM1 i2d exp PFK2 GRR1 11805837 dip exp SBP1 GRR1 23222640 biogrid exp GRR1 STP1 21127045 biogrid exp GRR1 PH domain-containing protein YHR131C 24389104 biogrid exp GRR1 Uncharacterized protein YNL144C 24389104 biogrid exp GRR1 CDC48 11805837 dip exp GRR1 NAB2 19840948 biogrid exp GRR1 HTZ1 i2d exp POR1 GRR1 11805837 biogrid,intact,dip exp GRR1 SSY5 21653827 biogrid exp GRR1 SHO1 11743162 mint exp GRR1 Inactive deaminase YBR284W 11283351 i2d,mint,intact,dip exp GRR1 TIS11 24389104 biogrid exp CLN1 GRR1 24389104,22844257,10213692,9346238 biogrid,dip exp GRR1 LSB3 11743162 mint exp GRR1 SWA2 19536198 intact exp GRR1 BUD4 24389104 biogrid exp GRR1 MKS1 16093347 biogrid exp GRR1 Uncharacterized protein YKR045C 24389104 biogrid exp GRR1 GIC2 24389104,23144720 biogrid exp GRR1 ALD4 11805837 dip exp GRR1 SFG1 24389104 biogrid exp GRR1 YSC84 11743162 mint exp GRR1 GCD6 20489023 biogrid,mint,intact exp GRR1 HEK2 18805955 biogrid exp GRR1 CDC55 i2d exp CIT1 GRR1 11805837 dip exp GRR1 SHE3 23144720 biogrid exp GRR1 PGD1 24550274 biogrid exp CDC28 GRR1 12052857,25049391,9346238 biogrid,dip exp GAL1 GRR1 11805837 dip exp GRR1 CUR1 11283351 mint exp LAT1 GRR1 11805837 dip exp GRR1 TAM41 14690591 intact exp SAM2 GRR1 11805837 dip exp GRR1 SKP1 20489023,23535662,9491072,9499404,9819356,11805837,10430906,11283612,10688190,23000173,10582239,19882662,14747994,23267104,12008900,9312022,11259599,10213692,20581845,9346238, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred GRR1 GAC1 24389104, 23023127 biogrid exp, pred GRR1 HOF1 11283351,15775961, 23023127 biogrid,i2d,mint,intact,dip exp, pred GRR1 COF1 11805837, 23023127 biogrid,intact,dip exp, pred GRR1 CDC53 20489023,23535662,23267104,9499404,11805837,11259599,10582239,19882662,10213692,14747994,9346238, 23023127 biogrid,i2d,mint,intact,dip exp, pred GRR1 RRI2 23144720, 23023127 biogrid exp, pred GRR1 TYE7 24389104,17828247, 23023127 biogrid exp, pred GRR1 BZZ1 11743162, 23023127 biogrid,i2d,mint,intact,dip exp, pred CPR1 GRR1 11805837, 23023127 biogrid,intact,dip exp, pred GRR1 PFK27 24389104,23144720,17828247, 23023127 biogrid exp, pred GRR1 NPR2 20154027, 23023127 biogrid exp, pred GRR1 HRT1 10880467,10213692,19882662,14747994, 23023127 biogrid,intact,dip exp, pred PFK1 GRR1 11805837, 23023127 biogrid,intact,dip exp, pred CLN2 GRR1 12052857,9819356,24389104,11259599,22844257,10582239,18787112,10579999,15200949, 23023127 biogrid,i2d,dip exp, pred CDC34 GRR1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred GRR1 REG1 15849787, 23023127 biogrid exp, pred GRR1 BMH2 15849787, 23023127 biogrid exp, pred PDC5 GRR1 11805837, 23023127 biogrid,intact,dip exp, pred GRR1 RAD23 ortho PPH21 GRR1 23023127 pred GRR1 SAP155 23023127 pred SEC4 GRR1 23023127 pred CDC42 GRR1 23023127 pred GRR1 CDC11 23023127 pred CDC24 GRR1 23023127 pred GRR1 UBI4 23023127 pred GRR1 FAR10 23023127 pred FAR1 GRR1 23023127 pred PPH22 GRR1 23023127 pred GRR1 F-box protein YDR131C 23023127 pred GRR1 FAR11 23023127 pred RAD18 GRR1 23023127 pred RAS2 GRR1 23023127 pred CDC25 GRR1 23023127 pred GRR1 YKU70 23023127 pred GRR1 MET30 23023127 pred CDC4 GRR1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P24814 P20438 - 15200949 - X 2 P24814 P38822 - 11743162 - X 2 P24814 P20438 - 12052857 - X 2 P24814 P38150 - 11283351 - X 2 P24814 P0C2J0 - 11283351 - X 2 P24814 - 11805837 - C 13 P24814 - 15200949 - C 19 P24814 - 11805837 - C 3 P24814 P52286 - 11805837 - X 2 P24814 Q12018 - 9499404 - X 2 P24814 P52286 - 10688190 - X 2 P24814 P52286 - 11283612 - X 2 P24814 P52286 - 9312022 - X 2 P24814 P52286 - 9491072 - X 2 P24814 P52286 - 9499404 - X 2 P24814 Q05080 - 11283351 - X 2 P24814 Q05080 - 15775961 - X 2 P0CG63 P24814 affinity chromatography technology 23749301 physical association X 2 P0CG63 P24814 biochemical 23583075 association X 2 P0CG63 P24814 affinity chromatography technology 17644757 physical association X 2 P0CG63 P24814 affinity chromatography technology 9844630 physical association X 2 P0CG63 P24814 affinity chromatography technology 11805837 physical association X 2 P24814 P20438 affinity chromatography technology 11259599 physical association X 2 P24814 Q08273 affinity chromatography technology 10213692 physical association X 2 P24814 P20438 affinity chromatography technology 9819356 physical association X 2 P24814 Q08273 two hybrid 10880467 direct interaction X 2 P24814 Q08273 two hybrid 10880467 direct interaction X 2 P24814 Q08273 pull down 14747994 direct interaction X 2 P24814 P20438 affinity chromatography technology 10582239 physical association X 2 P24814 P20438 affinity chromatography technology 12052857 physical association X 2 P24814 O13329 two hybrid 23144720 direct interaction X 2 P24814 Q08729 two hybrid 23144720 direct interaction X 2 P24814 Q12471 two hybrid 23144720 direct interaction X 2 P24814 Q06648 two hybrid 23144720 direct interaction X 2 P24814 P38272 two hybrid 23144720 direct interaction X 2 P24814 P20438 affinity chromatography technology 15200949 physical association X 2 P24814 P20438 affinity chromatography technology 15200949 physical association X 2 P24814 P35198 affinity chromatography technology 15456873 physical association X 2 P24814 P35198 affinity chromatography technology 15456873 physical association X 2 P24814 P38822 two hybrid 11743162 direct interaction X 2 P24814 P34730 two hybrid 15849787 direct interaction X 2 P24814 P34730 affinity chromatography technology 15849787 physical association X 2 P24814 Q12471 affinity chromatography technology 24389104 physical association X 2 P24814 P47136 affinity chromatography technology 24389104 physical association X 2 P24814 P42223 affinity chromatography technology 24389104 physical association X 2 P24814 P47977 affinity chromatography technology 24389104 physical association X 2 P24814 P38835 affinity chromatography technology 24389104 physical association X 2 P24814 P36138 affinity chromatography technology 24389104 physical association X 2 P24814 P20437 affinity chromatography technology 24389104 physical association X 2 P24814 P20438 affinity chromatography technology 24389104 physical association X 2 P24814 Q06648 affinity chromatography technology 24389104 physical association X 2 P24814 P35198 affinity chromatography technology 24389104 physical association X 2 P24814 Q12471 affinity chromatography technology 24389104 physical association X 2 P24814 P33122 affinity chromatography technology 24389104 physical association X 2 P24814 P20437 pull down 9346238 direct interaction X 2 P24814 P20437 enzymatic study 10213692 direct interaction X 2 P24814 P20438 pull down 12052857 direct interaction X 2 P24814 P20438 enzymatic study 10579999 direct interaction X 2 P24814 Q12471 pull down 17828247 direct interaction X 2 P24814 P33122 pull down 17828247 direct interaction X 2 P24814 P20438 two hybrid 18787112 direct interaction X 2 P24814 Q39255 two hybrid 12008900 direct interaction X 2 P24814 P39923 affinity chromatography technology 20154027 physical association X 2 P24814 P39923 affinity chromatography technology 20154027 physical association X 2 P24814 P32501 affinity chromatography technology 20489023 physical association X 2 P24814 Q00947 affinity chromatography technology 21127045 physical association X 2 P24814 P47002 two hybrid 21653827 direct interaction X 2 P24814 Q03048 affinity chromatography technology 11805837 physical association X 2 P24814 P04840 affinity chromatography technology 11805837 physical association X 2 P24814 P51601 affinity chromatography technology 11805837 physical association X 2 P24814 P16861 affinity chromatography technology 11805837 physical association X 2 P24814 P14832 affinity chromatography technology 11805837 physical association X 2 P24814 P39954 affinity chromatography technology 11805837 physical association X 2 P24814 P13365 affinity chromatography technology 22844257 physical association X 2 P24814 P52286 pull down 23000173 direct interaction X 2 P24814 Q12018 affinity chromatography technology 11259599 physical association X 2 P24814 P52286 affinity chromatography technology 11259599 physical association X 2 P24814 Q12018 affinity chromatography technology 10213692 physical association X 2 P24814 Q12018 affinity chromatography technology 9346238 physical association X 2 P24814 P52286 affinity chromatography technology 10213692 physical association X 2 P24814 P52286 affinity chromatography technology 9346238 physical association X 2 P24814 Q12018 affinity chromatography technology 9499404 physical association X 2 P24814 P52286 affinity chromatography technology 9312022 physical association X 2 P24814 P52286 affinity chromatography technology 11283612 physical association X 2 P24814 P52286 affinity chromatography technology 9819356 physical association X 2 P24814 P52286 pull down 9312022 direct interaction X 2 P24814 P52286 pull down 9491072 direct interaction X 2 P24814 P52286 two hybrid 9312022 direct interaction X 2 P24814 P52286 two hybrid 11283612 direct interaction X 2 P24814 P52286 pull down 14747994 direct interaction X 2 P24814 Q12018 pull down 14747994 direct interaction X 2 P24814 Q12018 affinity chromatography technology 10582239 physical association X 2 P24814 Q12018 affinity chromatography technology 10582239 physical association X 2 P24814 P52286 affinity chromatography technology 10582239 physical association X 2 P24814 P52286 two hybrid 10430906 direct interaction X 2 P24814 P52286 affinity chromatography technology 10430906 physical association X 2 P24814 P40572 two hybrid 23144720 direct interaction X 2 P24814 Q03338 two hybrid 23144720 direct interaction X 2 P24814 Q12348 two hybrid 23144720 direct interaction X 2 P24814 P52286 affinity chromatography technology 9499404 physical association X 2 P24814 P52286 affinity chromatography technology 23535662 physical association X 2 P24814 Q12018 affinity chromatography technology 23535662 physical association X 2 P24814 Q05080 two hybrid 15775961 direct interaction X 2 P24814 Q04233 two hybrid 15890364 direct interaction X 2 P24814 Q04233 affinity chromatography technology 15890364 physical association X 2 P24814 Q00816 two hybrid 15849787 direct interaction X 2 P24814 Q00816 affinity chromatography technology 15849787 physical association X 2 P24814 P40020 affinity chromatography technology 24389104 physical association X 2 P24814 P28006 affinity chromatography technology 24389104 physical association X 2 P24814 Q12507 affinity chromatography technology 24389104 physical association X 2 P24814 P53907 affinity chromatography technology 24389104 physical association X 2 P24814 P00546 enzymatic study 25049391 direct interaction X 2 P24814 P00546 pull down 9346238 direct interaction X 2 P24814 P52286 affinity chromatography technology 9312022 physical association X 2 P24814 P52286 pull down 9312022 direct interaction X 2 P24814 affinity chromatography technology 10213692 physical association X 2 P24814 P52286 biochemical 10213692 association X 2 P24814 Q05080 protein complementation assay 15775961 direct interaction X 2 P24814 Q05080 fluorescent resonance energy transfer 15775961 direct interaction X 2 P24814 P40356 pull down 24550274 direct interaction X 2 P24814 P40356 two hybrid 24550274 direct interaction X 2 P24814 P14682 affinity chromatography technology 16554755 physical association X 2 P24814 P34072 affinity chromatography technology 16093347 physical association X 2 P24814 P34072 affinity chromatography technology 16093347 physical association X 2 P24814 P34072 pull down 16093347 direct interaction X 2 P24814 P39077 affinity chromatography technology 18511909 physical association X 2 P24814 Q9FHW7 two hybrid 12008900 direct interaction X 2 P24814 Q12018 affinity chromatography technology 20489023 physical association X 2 P24814 P52286 affinity chromatography technology 20489023 physical association X 2 P24814 P52286 affinity chromatography technology 20581845 physical association X 2 P24814 P38704 affinity chromatography technology 21127045 physical association X 2 P24814 Q12018 affinity chromatography technology 11805837 physical association X 2 P24814 P52286 affinity chromatography technology 11805837 physical association X 2 P24814 P02294 affinity chromatography technology 11805837 physical association X 2 P24814 P26263 affinity chromatography technology 11805837 physical association X 2 P24814 P16467 affinity chromatography technology 11805837 physical association X 2 P24814 P52286 two hybrid 10688190 direct interaction X 2 P24814 affinity chromatography technology 14747994 - C 4 P24814 anti tag coimmunoprecipitation 11805837 - C 22 P12695 P24814 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P46367 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P25694 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P00890 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P16862 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P12709 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P38150 two hybrid pooling approach 11283351 physical association X 2 P24814 P38822 two hybrid 11743162 physical association X 2 P24814 Q03048 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P14832 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P51601 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P16861 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P04840 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P39954 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P05759 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P20437 coimmunoprecipitation 9346238 physical association X 2 P24814 P20438 coimmunoprecipitation 9819356 physical association X 2 P24814 P20438 two hybrid 18787112 physical association X 2 P24814 P20438 affinity chromatography technology 12052857 physical association X 2 P24814 P20438 coimmunoprecipitation 12052857 physical association X 2 P24814 Q08273 two hybrid 10880467 physical association X 2 P24814 Q08273 coimmunoprecipitation 10213692 physical association X 2 P24814 anti tag coimmunoprecipitation 11805837 - C 13 P24814 coimmunoprecipitation 9346238 - C 4 P24814 P04385 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P19358 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 Q08224 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 Q05080 two hybrid pooling approach 11283351 physical association X 2 P24814 P02294 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P16467 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P26263 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P52286 two hybrid 10688190 physical association X 2 P24814 P52286 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 P52286 affinity chromatography technology 14747994 physical association X 2 P24814 P52286 two hybrid 9312022 physical association X 2 P24814 P52286 affinity chromatography technology 9491072 physical association X 2 P24814 P52286 coimmunoprecipitation 9312022 physical association X 2 P24814 P52286 coimmunoprecipitation 9346238 physical association X 2 P24814 P52286 coimmunoprecipitation 11283612 physical association X 2 P24814 P52286 coimmunoprecipitation 10213692 physical association X 2 P24814 P52286 coimmunoprecipitation 9346238 physical association X 2 P24814 P52286 coimmunoprecipitation 10213692 physical association X 2 P24814 P00546 coimmunoprecipitation 12052857 physical association X 2 P24814 Q12018 coimmunoprecipitation 9346238 physical association X 2 P24814 Q12018 coimmunoprecipitation 9499404 physical association X 2 P24814 Q12018 anti tag coimmunoprecipitation 11805837 physical association X 2 P24814 Q12018 coimmunoprecipitation 10213692 physical association X 2 P24814 pull down 19882662 association C 41 P24814 inferred by author 16554755 association C 12 P24814 anti tag coimmunoprecipitation 9499404 association C 6 P24814 pull down 19882662 association C 35 P24814 anti tag coimmunoprecipitation 20489023 association C 4 P24814 P38150 two hybrid fragment pooling approach 11283351 physical association X 2 P24814 P38822 two hybrid 11743162 physical association X 2 P24814 Q39255 two hybrid 12008900 physical association X 2 P24814 P53230 two hybrid array 14690591 physical association X 2 P24814 Q06677 tandem affinity purification 19536198 association X 2 P24814 P39743 inferred by author 19841731 direct interaction X 2 P24814 anti tag coimmunoprecipitation 9499404 association C 5 P24814 pull down 19882662 association C 51 P24814 anti tag coimmunoprecipitation 11805837 association C 13 P24814 anti tag coimmunoprecipitation 11805837 association C 3 P24814 anti tag coimmunoprecipitation 9499404 association C 3 P24814 P52286 two hybrid 10688190 physical association X 2 P24814 Q05080 two hybrid fragment pooling approach 11283351 physical association X 2 P24814 P52286 anti tag coimmunoprecipitation 11805837 association X 2 P24814 P52286 two hybrid 12008900 physical association X 2 P24814 Q9FHW7 two hybrid 12008900 physical association X 2 P24814 P14682 tandem affinity purification 16554755 physical association X 2 P24814 P14682 tandem affinity purification 16554755 physical association X 2 P24814 P14682 tandem affinity purification 16554755 physical association X 2 P24814 P47079 tandem affinity purification 19536198 association X 2 P24814 P52286 miniaturized immunoprecipitation 23267104 direct interaction X 2 P24814 Q12018 miniaturized immunoprecipitation 23267104 direct interaction X 2 P24814 Q12018 miniaturized immunoprecipitation 23267104 direct interaction X 2 P24814 Q12018 two hybrid 9499404 physical association X 2 P24814 P38822 two hybrid 11743162 - X 2 P24814 P38150 two hybrid 11283351 - X 2 P24814 Q00362 interaction detection method 7962097 - X 2 P24814 confirmational text mining - - C 4 P24814 mass spectrometry studies of complexes 11805837 - C 14 P24814 mass spectrometry studies of complexes 11805837 - C 14 P24814 P32801 interaction detection method 7498768 - X 2 P24814 Q05080 two hybrid 11283351 - X 2 P24814 Q12018 coimmunoprecipitation 9499404 - X 2 P24814 P14682 interaction detection method 9491072 - X 2 P24814 P52286 two hybrid 10688190 - X 2 P24814 P52286 coimmunoprecipitation 9312022 - X 2 P24814 P52286 two hybrid 10688190,9312022 - X 2 P24814 P52286 coimmunoprecipitation 9312022,9499404 - X 2 P24814 P52286 affinity chromatography technology 9491072 - X 2 P24814 P52286 coimmunoprecipitation 9499404 - X 2

PPI - HINT Gene A Gene B PMID Method Quality FOB1 GRR1 23144720 0018 LC CDC28 GRR1 12052857,25049391 0019,0415 LC TY1B-PR2 GRR1 11283351 0018 HT CLN1 GRR1 9346238,10213692,9346238 0096,0415,0019 LC CLN2 GRR1 10579999,12052857,12052857,18787112,9819356,9819356,12052857 0415,0019,0004,0018,0019,0004,0096 LC GRR1 BMH2 15849787,15849787 0004,0018 LC GRR1 P38150 11283351,11283351,11283351 0018,0399,0398 HT GRR1 SHE3 23144720 0018 LC GRR1 BZZ1 11743162,11743162 0397,0018 HT GRR1 PGD1 24550274,24550274 0096,0018 LC GRR1 P40572 23144720 0018 LC GRR1 SSY5 21653827 0018 LC GRR1 SKP1 10430906,12008900,10430906,10213692,9499404,11283612,9312022,10688190,10213692,11283612,23267104,11283612,9499404,10213692,9312022,9312022,9346238,9346238,10688190,9499404,9312022 0018,0018,0004,0401,0019,0018,0096,0397,0004,0004,0946,0019,0007,0019,0018,0004,0004,0019,0018,0004,0019 LC,HT GRR1 TAM41 14690591 0397 LC GRR1 REG1 15849787,15849787 0004,0018 LC GRR1 PRP3 23144720 0018 LC GRR1 GIS4 15890364,15890364 0004,0018 LC GRR1 HOF1 15775961,15775961,15775961,11283351,11283351,15775961,11283351,15775961 0428,0055,0045,0018,0399,0090,0398,0018 LC,HT GRR1 CUR1 11283351 0398 HT GRR1 GIC2 23144720 0018 LC GRR1 HRT1 10213692,10213692,10880467 0019,0004,0018 LC GRR1 DSE3 23144720 0018 LC GRR1 CDC53 10213692,10213692,23267104,9499404,9346238,9499404,9346238,9499404,9499404 0019,0004,0946,0019,0004,0007,0019,0004,0018 LC GRR1 RRI2 23144720 0018 LC GRR1 PFK27 23144720 0018 LC CDC28 GRR1 9346238 0096 LC CIT1 GRR1 11805837 0007 HT HTB2 GRR1 11805837,11805837 0004,0007 HT GAL1 GRR1 11805837 0007 HT POR1 GRR1 11805837,11805837 0004,0007 HT RPS31 GRR1 11805837 0007 HT UBI4 GRR1 11805837 0004 HT RPL40B GRR1 11805837 0007 HT LAT1 GRR1 11805837 0007 HT PGI1 GRR1 11805837 0007 HT CLN3 GRR1 22844257 0004 LC CDC34 GRR1 16554755,16554755 0676,0004 HT CPR1 GRR1 11805837,11805837 0004,0007 HT PDC5 GRR1 11805837,11805837 0004,0007 HT PFK1 GRR1 11805837,11805837 0004,0007 HT PFK2 GRR1 11805837 0007 HT SAM2 GRR1 11805837 0007 HT CLN1 GRR1 9346238,9346238,22844257,24389104 0096,0019,0004,0004 LC CLN2 GRR1 22844257,12052857,12052857,10582239,15200949,24389104,9819356,9819356,11259599,12052857 0004,0019,0004,0004,0004,0004,0019,0004,0004,0096 LC GRR1 CDC48 11805837 0007 HT GRR1 PDC6 11805837,11805837 0004,0007 HT GRR1 GAC1 24389104 0004 LC GRR1 GCD6 20489023,20489023 0007,0004 HT GRR1 NAB2 19840948 0004 LC GRR1 TYE7 17828247,24389104 0096,0004 LC GRR1 MKS1 16093347,16093347 0004,0096 LC GRR1 BMH2 15849787,15849787 0004,0018 LC GRR1 MTH1 15456873,24389104 0004,0004 LC GRR1 P36138 24389104 0004 LC GRR1 STP2 21127045 0004 LC GRR1 P38835 24389104 0004 LC GRR1 CCT3 18511909 0004 LC GRR1 RVS167 19841731 0363 LC GRR1 NPR2 20154027 0004 LC GRR1 SAH1 11805837,11805837 0004,0007 HT GRR1 FIR1 24389104 0004 LC GRR1 PGD1 24550274,24550274 0096,0018 LC GRR1 SBE2 24389104 0004 LC GRR1 CAK1 16554755 0363 HT GRR1 ALD4 11805837 0007 HT GRR1 CCT8 19536198 0676 HT GRR1 BUD4 24389104 0004 LC GRR1 TIS11 24389104 0004 LC GRR1 FOL2 11805837,11805837 0004,0007 HT GRR1 SKP1 10430906,19882662,20581845,14747994,10430906,10213692,23000173,9499404,9491072,11283612,9312022,23535662,11805837,10213692,11283612,11283612,9499404,20489023,9819356,9491072,11805837,10213692,9312022,9312022,14747994,9346238,10582239,9346238,9499404,11259599,20489023,9312022 0018,0096,0004,0096,0004,0401,0096,0019,0004,0018,0096,0004,0004,0004,0004,0019,0007,0004,0004,0096,0007,0019,0018,0004,0004,0004,0004,0019,0004,0004,0007,0019 LC,HT GRR1 P53907 24389104 0004 LC GRR1 REG1 15849787,15849787 0004,0018 LC GRR1 STP1 21127045 0004 LC GRR1 COF1 11805837,11805837 0004,0007 HT GRR1 GIS4 15890364,15890364 0004,0018 LC GRR1 HOF1 15775961,15775961,15775961,15775961,15775961 0428,0055,0045,0090,0018 LC GRR1 GIC2 24389104 0004 LC GRR1 SWA2 19536198 0676 HT GRR1 THI20 11805837 0007 HT GRR1 HRT1 10213692,10213692,19882662,14747994 0019,0004,0096,0096 LC GRR1 NDD1 25894965 0004 LC GRR1 CDC53 10213692,20489023,10213692,19882662,9499404,9346238,9499404,10582239,14747994,11805837,9346238,11805837,9499404,9499404,20489023,11259599,23535662 0019,0004,0004,0096,0019,0004,0007,0004,0096,0007,0019,0004,0004,0018,0007,0004,0004 LC,HT GRR1 PFK27 17828247,24389104 0096,0004 LC GRR1 SFG1 24389104 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53230 P24814 TAM41 GRR1 0.126 14690591 P61864 P24814 RPL40A GRR1 0.236 11805837 P24814 O13329 GRR1 FOB1 0.309 23144720 P24814 P00546 GRR1 CDC28 0.523 9346238,12052857,25049391 P24814 P04840 GRR1 POR1 0.286 11805837 P24814 P0CG63 GRR1 UBI4 0.126 11805837 P24814 P13365 GRR1 CLN3 0.21 22844257 P24814 P16467 GRR1 PDC5 0.286 11805837 P24814 P16861 GRR1 PFK1 0.286 11805837 P24814 P16862 GRR1 PFK2 0.126 11805837 P24814 P20437 GRR1 CLN1 0.671 9346238,24389104,10213692,22844257 P28006 P24814 GAC1 GRR1 0.21 24389104 P36138 P24814 P36138 GRR1 0.21 24389104 P38272 P24814 SHE3 GRR1 0.309 23144720 P38704 P24814 STP2 GRR1 0.21 21127045 P38835 P24814 P38835 GRR1 0.21 24389104 P40020 P24814 FIR1 GRR1 0.21 24389104 P40572 P24814 P40572 GRR1 0.309 23144720 P42223 P24814 SBE2 GRR1 0.21 24389104 P47002 P24814 SSY5 GRR1 0.309 21653827 P47079 P24814 CCT8 GRR1 0.126 19536198 P47136 P24814 BUD4 GRR1 0.21 24389104 P47977 P24814 TIS11 GRR1 0.21 24389104 P53907 P24814 P53907 GRR1 0.21 24389104 Q00947 P24814 STP1 GRR1 0.21 21127045 Q03048 P24814 COF1 GRR1 0.286 11805837 Q03338 P24814 PRP3 GRR1 0.309 23144720 Q06677 P24814 SWA2 GRR1 0.126 19536198 Q08729 P24814 DSE3 GRR1 0.309 23144720 Q08887 P24814 NDD1 GRR1 0.21 25894965 Q12348 P24814 RRI2 GRR1 0.309 23144720 Q12507 P24814 SFG1 GRR1 0.21 24389104 Q9Y297 P24814 BTRC GRR1 0.21 10213692 P25694 P24814 CDC48 GRR1 0.126 11805837 P24814 P10080 GRR1 SBP1 0.126 23222640 P24814 P00890 GRR1 CIT1 0.126 11805837 P24814 P02294 GRR1 HTB2 0.332 11805837 P24814 P12695 GRR1 LAT1 0.126 11805837 P24814 P12709 GRR1 PGI1 0.126 11805837 P24814 P04385 GRR1 GAL1 0.126 11805837 P33122 P24814 TYE7 GRR1 0.454 17828247,24389104 Q06648 P24814 GIC2 GRR1 0.454 24389104,23144720 Q39255 P24814 SKP1A GRR1 0.523 12008900 Q9FHW7 P24814 SKP1B GRR1 0.523 12008900 Q12471 P24814 PFK27 GRR1 0.623 24389104,23144720,17828247 Q12018 P24814 CDC53 GRR1 0.948 9499404,23267104,10582239,11805837,19882662,10213692,14747994,23535662,20489023,9346238 P52286 P24814 SKP1 GRR1 0.994 9499404,23267104,10582239,20581845,11805837,9346238,12008900,11283612,9491072,10430906,19882662,14747994,10213692,23535662,23000173,20489023,10688190,9312022 P35198 P24814 MTH1 GRR1 0.507 24389104,15456873 P38150 P24814 P38150 GRR1 0.21 11283351 P38199 P24814 HEK2 GRR1 0.126 18805955 P26263 P24814 PDC6 GRR1 0.332 11805837 P32501 P24814 GCD6 GRR1 0.332 20489023 P32505 P24814 NAB2 GRR1 0.126 19840948 P38822 P24814 BZZ1 GRR1 0.21 11743162 P39077 P24814 CCT3 GRR1 0.126 18511909 P39743 P24814 RVS167 GRR1 0.332 19841731 P39923 P24814 NPR2 GRR1 0.376 20154027 P39954 P24814 SAH1 GRR1 0.332 11805837 P34072 P24814 MKS1 GRR1 0.569 16093347 P43568 P24814 CAK1 GRR1 0.126 16554755 P40356 P24814 PGD1 GRR1 0.523 24550274 P46367 P24814 ALD4 GRR1 0.126 11805837 P24814 P14682 GRR1 CDC34 0.236 16554755 P24814 P14832 GRR1 CPR1 0.332 11805837 P24814 P19358 GRR1 SAM2 0.126 11805837 P51601 P24814 FOL2 GRR1 0.332 11805837 P24814 P20438 GRR1 CLN2 0.902 10582239,22844257,18787112,9819356,10579999,24389104,12052857 Q05080 P24814 HOF1 GRR1 0.712 11283351,15775961 Q08224 P24814 THI20 GRR1 0.126 11805837 Q08273 P24814 HRT1 GRR1 0.21 19882662,10213692,10880467