PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RPL40A YUH1 i2d exp PRS1 YUH1 11283351 i2d,mint,intact,dip exp YUH1 NAF1 14690591 intact exp GFA1 YUH1 i2d exp NAB2 YUH1 19840948 biogrid exp RFA1 YUH1 25719602 biogrid exp YUH1 SSB2 23332755 biogrid exp SSB1 YUH1 19536198 intact exp YUH1 RPN6 i2d exp HSP78 YUH1 19536198 intact exp UBI4 YUH1 19520148,10512618,10413498 biogrid,i2d exp YUH1 STD1 11283351 i2d,mint,intact,dip exp YUH1 PTK2 16319894 biogrid,i2d exp RPL40B YUH1 1429680 biogrid,i2d exp YUH1 GND2 i2d exp YUH1 YUH1 i2d exp, ortho RPS31 YUH1 1429680 biogrid,i2d exp, ortho YUH1 RUB1 12455997, 23023127 biogrid exp, ortho, pred YUH1 GDI1 ortho YUH1 GPX2 ortho LPD1 YUH1 ortho INO1 YUH1 ortho CSE1 YUH1 ortho SOD2 YUH1 ortho PDI1 YUH1 ortho YUH1 RDI1 ortho STI1 YUH1 ortho YUH1 BIM1 ortho YUH1 CPR5 ortho NIC96 YUH1 ortho YUH1 VMA7 ortho YUH1 UFD2 ortho UBA1 YUH1 23023127 ortho, pred YUH1 UBX3 23023127 pred YUH1 UBX4 23023127 pred SHP1 YUH1 23023127 pred YUH1 DSK2 23023127 pred YUH1 UBX5 23023127 pred YUH1 UBI4 23023127 pred RAD23 YUH1 23023127 pred YUH1 UBX6 23023127 pred YUH1 HUB1 23023127 pred YUH1 ATG12 23023127 pred YUH1 SMT3 23023127 pred YUH1 ATG8 23023127 pred YUH1 UBX7 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P35127 P35127 - 10406793,9233788 - X 2 P35127 P35127 - 10406793,9233788 - X 2 P35127 Q02794 - 11283351 - X 2 P35127 P32895 - 11283351 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CG63 P35127 x-ray crystallography 19520148 association X 2 P35127 Q03919 enzymatic study 12455997 direct interaction X 2 P35127 P62987 enzymatic study 10527495 direct interaction X 2 P35127 P40150 biochemical 23332755 association X 2 P35127 P47116 enzymatic study 16319894 direct interaction X 2 P0CH08 P35127 enzymatic study 1429680 direct interaction X 2 P35127 P05759 enzymatic study 1429680 direct interaction X 2 P35127 P0CG48 enzymatic study 24961813 direct interaction X 2 P35127 Q02794 two hybrid pooling approach 11283351 physical association X 2 P35127 P32895 two hybrid pooling approach 11283351 physical association X 2 P35127 P32895 two hybrid fragment pooling approach 11283351 physical association X 2 P35127 Q02794 two hybrid fragment pooling approach 11283351 physical association X 2 P35127 P33416 tandem affinity purification 19536198 association X 2 P35127 P53919 two hybrid array 14690591 physical association X 2 P35127 P11484 tandem affinity purification 19536198 association X 2 P35127 P32895 two hybrid 11283351 - X 2 P35127 Q02794 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality RPS31 YUH1 1429680 0415 LC UBI4 YUH1 10413498,19520148 0114,0114 LC RPL40A YUH1 9233788,1429680 0114,0415 LC RPL40B YUH1 1429680 0415 LC RFA1 YUH1 25719602 0018 LC UBA1 YUH1 10406793 0114 LC PRS1 YUH1 11283351,11283351,11283351 0018,0399,0398 HT YUH1 YUH1 9233788,10406793 0114,0114 LC YUH1 SSB2 23332755 0401 LC YUH1 PTK2 16319894 0415 LC YUH1 NAF1 14690591 0397 LC YUH1 STD1 11283351,11283351,11283351 0018,0399,0398 HT YUH1 RUB1 12455997 0415 LC UBI4 YUH1 10512618 0096 LC SSB1 YUH1 19536198 0676 HT NAB2 YUH1 19840948 0004 LC HSP78 YUH1 19536198 0676 HT YUH1 SSB2 23332755 0401 LC YUH1 ENT5 25512335 0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P35127 P22336 YUH1 RFA1 0.309 25719602 P35127 P0CG63 YUH1 UBI4 0.671 19520148,10512618,10413498 P35127 P32505 YUH1 NAB2 0.126 19840948 P35127 P32895 YUH1 PRS1 0.236 11283351 P35127 P33416 YUH1 HSP78 0.126 19536198 P40150 P35127 SSB2 YUH1 0.126 23332755 P35127 P05759 YUH1 RPS31 0.309 1429680 P35127 P0CG48 YUH1 UBC 0.309 24961813 P35127 P0CH08 YUH1 RPL40A 0.309 1429680 P35127 P0CH09 YUH1 RPL40B 0.309 1429680 P35127 P11484 YUH1 SSB1 0.126 19536198 P53919 P35127 NAF1 YUH1 0.126 14690591 P62987 P35127 UBA52 YUH1 0.309 10527495 Q03919 P35127 RUB1 YUH1 0.309 12455997 P47116 P35127 PTK2 YUH1 0.183 16319894 Q02794 P35127 STD1 YUH1 0.21 11283351 Q03769 P35127 ENT5 YUH1 0.183 25512335