PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CDC16 YEF3 16429126 biogrid,intact exp CDC16 RPL4B 16429126 intact exp CDC16 PPH21 23751495 biogrid exp CDC16 SSB1 16429126,19536198 intact exp URA2 CDC16 16429126 intact exp PDC1 CDC16 16429126 intact exp FAS1 CDC16 16429126 intact exp CDC16 SSA2 16429126 intact exp CDC16 PPH22 23751495 biogrid exp TEF1, TEF2 CDC16 16429126 intact exp CDC16 PSA1 16429126 intact exp CDC16 RPL5 16429126 intact exp CDC16 AIM4 21386897 biogrid exp CDC19 CDC16 16429126 intact exp CDC16 VMA2 16429126 intact exp CDC16 SSA1 19536198 intact exp CDC16 ECM10 19536198 intact exp CDC16 SPT21 25228766 biogrid exp CDC16 RVS167 i2d exp CDC16 URN1 21386897 biogrid exp CDC16 SSE1 19536198 intact exp CDC16 ORC6 i2d exp CDC16 CDH1 9831566,25025567,15916960, 23023127 biogrid,dip exp, ortho, pred CDC16 CDC23 10318877,16429126,12402045,21186364,9469814,16364911,8895471,15060174,16275330,17406682,12887895,15797379,16481473,16554755,7925276,15649358,23751495, 23023127 biogrid,i2d,mint,intact,dip exp, ortho, pred CDC16 APC11 10318877,21186364,9469814,16364911,15649358,15060174,16275330,10888670,17406682,12574115,15797379, 23023127 biogrid,i2d,intact,dip exp, ortho, pred CDC16 CDC20 22940250,12887895,21118994, 23023127 biogrid exp, ortho, pred CDC16 RPT1 11029046, 23023127 biogrid exp, pred CDC16 MUS81 11805837, 23023127 biogrid,mint,intact,dip exp, pred CDC4 CDC16 23023127 i2d exp, pred CDC16 CDC16 15060174,21186364,9469814,7925276, 23023127 biogrid,dip exp, pred CDC16 PFD1 19536198, 23023127 intact exp, pred CDC16 APC4 10318877,16429126,12402045,21186364,9469814,16364911,16275330,15060174,17406682,12887895,15797379,12477395,21107322,16554755,15649358,12574115,23751495, 23023127 biogrid,i2d,mint,intact,dip exp, pred CDC16 SWM1 12477395,21107322,9469814,16364911,15649358,15060174,16275330,17406682,12609981,12574115,15797379, 23023127 biogrid,intact,dip exp, pred CDC16 AMA1 11114178, 23023127 biogrid,intact,dip exp, pred CDC16 APC2 9469815,10318877,16429126,12402045,21186364,9469814,16364911,16275330,15060174,17406682,12887895,15797379,16554755,11805826,15649358,12574115,23751495, 23023127 biogrid,i2d,mint,intact,dip exp, pred CDC16 CDC27 10318877,16429126,12402045,21186364,9469814,16364911,8895471,16275330,15060174,17406682,12887895,15797379,16554755,7925276,15649358,17459880,12609981,12574115,23751495, 23023127 biogrid,i2d,mint,intact,dip exp, pred CDC16 MND2 12477395,21186364,16364911,15649358,15060174,16275330,17406682,12609981,12574115,15797379, 23023127 biogrid,i2d,intact,dip exp, pred TUB1 CDC16 16429126, 23023127 intact exp, pred CDC28 CDC16 10871279,23751495, 23023127 biogrid exp, pred CDC16 APC5 10318877,16429126,12402045,21186364,9469814,16364911,15649358,15060174,16275330,17406682,12574115,23751495,12887895,15797379, 23023127 biogrid,i2d,intact,dip exp, pred CDC16 CDC5 10871279, 23023127 biogrid exp, pred TUB2 CDC16 16429126, 23023127 intact exp, pred CDC16 XRS2 11805837, 23023127 biogrid,mint,intact,dip exp, pred CDC16 CKS1 10871279, 23023127 biogrid exp, pred CDC16 DOC1 16429126,10318877,23267104,12402045,21186364,16554755,9469814,16364911,15649358,11805826,16275330,15060174,17406682,12574115,12887895,15797379, 23023127 biogrid,i2d,mint,intact,dip exp, pred CDC16 APC1 10318877,16429126,12402045,21186364,9469814,16364911,8895471,15060174,16275330,17406682,12887895,15797379,16481473,15649358,12574115,23751495, 23023127 biogrid,i2d,intact,dip exp, pred CDC16 APC9 10318877,16429126,12402045,21186364,9469814,16364911,15649358,15060174,16275330,17406682,12574115,12887895,15797379, 23023127 biogrid,i2d,intact,dip exp, pred CDC16 POL3 15649358, 23023127 biogrid exp, pred CDC16 CDC26 10318877,9469814,16364911,8895471,15060174,16275330,17406682,9348530,12574115,15797379, 23023127 biogrid,i2d,intact,dip exp, pred CDC16 RCM1 ortho CDC16 TAF5 ortho CDC16 CLB3 ortho CDC16 MEX67 ortho CDC16 MAD2 ortho CDC16 PPT1 ortho CDC16 UFD4 23023127 pred SEC4 CDC16 23023127 pred CDC16 DPB11 23023127 pred CDC16 DMA1 23023127 pred CDC16 CDC43 23023127 pred CDC16 RAD18 23023127 pred CDC16 NSL1 23023127 pred CDC16 COF1 23023127 pred CDC16 RBL2 23023127 pred CDC16 BUB1 23023127 pred CDC16 UBC9 23023127 pred CDC16 ASE1 23023127 pred CDC16 NNF1 23023127 pred CDC16 HRT1 23023127 pred CDC16 MET30 23023127 pred CDC16 EMW1 23023127 pred CDC16 CEP3 23023127 pred CDC16 MPE1 23023127 pred CDC16 SPC98 23023127 pred CDC16 TUL1 23023127 pred CDC16 BIK1 23023127 pred CDC16 ESP1 23023127 pred CDC16 DOA4 23023127 pred CDC16 TAF2 23023127 pred CDC16 UBC5 23023127 pred CDC16 SMT3 23023127 pred CDC16 UBA1 23023127 pred CDC16 MAD3 23023127 pred CDC16 ARP2 23023127 pred CDC16 UBA2 23023127 pred CDC16 UBI4 23023127 pred CDC16 PEX10 23023127 pred CDC16 CDC34 23023127 pred CDC16 TFC4 23023127 pred CDC16 SGT1 23023127 pred CDC6 CDC16 23023127 pred CDC16 SDS22 23023127 pred CDC16 ORC1 23023127 pred CDC16 DAD1 23023127 pred CDC16 RVS161 23023127 pred RHO1 CDC16 23023127 pred CDC16 ORC5 23023127 pred CDC16 ORC2 23023127 pred CDC16 CDC24 23023127 pred CDC16 RPN4 23023127 pred CDC16 TEM1 23023127 pred CDC16 MIP18 family protein YHR122W 23023127 pred CDC16 SKP1 23023127 pred CDC16 ARP10 23023127 pred CDC16 PRP19 23023127 pred CDC16 TOR2 23023127 pred CDC7 CDC16 23023127 pred CDC16 CTF8 23023127 pred CDC16 YDJ1 23023127 pred CDC16 CDC53 23023127 pred CDC16 ACT1 23023127 pred CDC16 MYO3 23023127 pred CDC16 POL12 23023127 pred SIR2 CDC16 23023127 pred CDC16 RSP5 23023127 pred CDC16 SNF7 23023127 pred CDC16 CDC42 23023127 pred CDC37 CDC16 23023127 pred CDC16 SLA2 23023127 pred CDC16 GGA1 23023127 pred CDC16 CLF1 23023127 pred CDC16 PAN1 23023127 pred CDC16 PDS1 23023127 pred CDC16 KAR2 23023127 pred CDC16 MYO2 23023127 pred CDC16 DYN1 23023127 pred RHO2 CDC16 23023127 pred CDC16 UBC11 23023127 pred CDC16 ARC15 23023127 pred CDC16 FPR3 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P09798 - 15797379 - C 13 P09798 - 15649358 - C 13 P09798 - 15916961 - C 7 P09798 - 9469814 - C 12 P09798 - 10888670 - C 3 P09798 - 11805826 - C 5 Q12157 P09798 - 9469814 - X 2 P09798 - 11734846 - X 2 P09798 - 9469814 - X 2 Q12107 P09798 - 9469814 - X 2 P09798 - 7925276 - X 2 P14724 P09798 - 9348530 - X 2 P09798 - 11805837 - C 6 P09798 - 15797379 - C 6 P09798 - 15044803 - C 11 P09798 - 11805826 - C 5 P09798 - 15916960 - C 3 P09798 - 11805837 - C 26 P09798 P16522 - 9469814 - X 2 Q08683 P09798 - 9469814 - X 2 Q04601 P09798 - 9469814 - X 2 P53068 P09798 - 9469814 - X 2 Q12440 P09798 affinity chromatography technology 12574115 physical association X 2 Q12440 P09798 affinity chromatography technology 10318877 physical association X 2 Q12440 P09798 affinity chromatography technology 12887895 physical association X 2 Q12440 P09798 affinity chromatography technology 12402045 physical association X 2 Q12440 P09798 affinity chromatography technology 15649358 physical association X 2 Q12440 P09798 affinity chromatography technology 9469815 physical association X 2 Q12440 P09798 affinity chromatography technology 15060174 physical association X 2 Q12440 P09798 affinity chromatography technology 15060174 physical association X 2 Q12440 P09798 affinity chromatography technology 9469814 physical association X 2 Q12440 P09798 affinity chromatography technology 23751495 physical association X 2 Q12440 P09798 affinity chromatography technology 16554755 physical association X 2 Q12440 P09798 affinity chromatography technology 16429126 physical association X 2 Q12440 P09798 affinity chromatography technology 16429126 physical association X 2 Q12440 P09798 affinity chromatography technology 16275330 physical association X 2 Q12440 P09798 affinity chromatography technology 17200106 physical association X 2 Q12440 P09798 affinity chromatography technology 17406682 physical association X 2 Q12440 P09798 affinity chromatography technology 15797379 physical association X 2 Q12440 P09798 affinity chromatography technology 15797379 physical association X 2 Q12440 P09798 affinity chromatography technology 21186364 physical association X 2 Q12440 P09798 affinity chromatography technology 11805826 physical association X 2 Q12440 P09798 affinity chromatography technology 16364911 physical association X 2 Q12157 P09798 affinity chromatography technology 12574115 physical association X 2 Q12157 P09798 affinity chromatography technology 10318877 physical association X 2 Q12157 P09798 affinity chromatography technology 15060174 physical association X 2 Q12157 P09798 affinity chromatography technology 9469814 physical association X 2 Q12157 P09798 affinity chromatography technology 10888670 physical association X 2 Q12157 P09798 affinity chromatography technology 15649358 physical association X 2 Q12157 P09798 affinity chromatography technology 16275330 physical association X 2 Q12157 P09798 affinity chromatography technology 17406682 physical association X 2 Q12157 P09798 affinity chromatography technology 15797379 physical association X 2 Q12157 P09798 affinity chromatography technology 21186364 physical association X 2 P38305 P09798 affinity chromatography technology 21386897 physical association X 2 Q12157 P09798 affinity chromatography technology 16364911 physical association X 2 P53886 P09798 affinity chromatography technology 12574115 physical association X 2 P53886 P09798 affinity chromatography technology 10318877 physical association X 2 P53886 P09798 affinity chromatography technology 8895471 physical association X 2 P53886 P09798 affinity chromatography technology 8895471 physical association X 2 P53886 P09798 affinity chromatography technology 12887895 physical association X 2 P53886 P09798 affinity chromatography technology 12402045 physical association X 2 P53886 P09798 affinity chromatography technology 15649358 physical association X 2 P53886 P09798 affinity chromatography technology 15060174 physical association X 2 P53886 P09798 affinity chromatography technology 9469814 physical association X 2 P53886 P09798 affinity chromatography technology 16481473 physical association X 2 P53886 P09798 affinity chromatography technology 23751495 physical association X 2 P53886 P09798 affinity chromatography technology 16429126 physical association X 2 P53886 P09798 affinity chromatography technology 16275330 physical association X 2 P53886 P09798 affinity chromatography technology 16481473 physical association X 2 P53886 P09798 affinity chromatography technology 17200106 physical association X 2 P53886 P09798 affinity chromatography technology 17406682 physical association X 2 P53886 P09798 affinity chromatography technology 15797379 physical association X 2 P53886 P09798 affinity chromatography technology 21186364 physical association X 2 P53886 P09798 affinity chromatography technology 16364911 physical association X 2 Q06525 P09798 affinity chromatography technology 21386897 physical association X 2 P35209 P09798 affinity chromatography technology 25228766 physical association X 2 P09798 P40577 affinity chromatography technology 12609981 physical association X 2 P09798 P40577 affinity chromatography technology 12574115 physical association X 2 P09798 P50082 affinity chromatography technology 11114178 physical association X 2 P09798 P09798 two hybrid 7925276 direct interaction X 2 P09798 P09798 affinity chromatography technology 15060174 physical association X 2 P09798 P40577 affinity chromatography technology 15060174 physical association X 2 P09798 P09798 affinity chromatography technology 9469814 physical association X 2 P09798 P40577 affinity chromatography technology 12477395 physical association X 2 P09798 P40577 affinity chromatography technology 15649358 physical association X 2 P09798 P32562 enzymatic study 10871279 direct interaction X 2 P09798 P23594 enzymatic study 23751495 direct interaction X 2 P09798 P23595 enzymatic study 23751495 direct interaction X 2 P09798 P16521 affinity chromatography technology 16429126 physical association X 2 P09798 P40577 affinity chromatography technology 16275330 physical association X 2 P09798 P40577 affinity chromatography technology 17406682 physical association X 2 P09798 P40577 affinity chromatography technology 15797379 physical association X 2 P09798 P40577 affinity chromatography technology 21186364 physical association X 2 P09798 P09798 affinity chromatography technology 21186364 physical association X 2 P09798 P33301 affinity chromatography technology 11805837 physical association X 2 P09798 P40577 affinity chromatography technology 16364911 physical association X 2 P26309 P09798 affinity chromatography technology 12887895 physical association X 2 P26309 P09798 affinity chromatography technology 21118994 physical association X 2 Q12107 P09798 affinity chromatography technology 12574115 physical association X 2 Q12107 P09798 affinity chromatography technology 10318877 physical association X 2 Q12107 P09798 affinity chromatography technology 12887895 physical association X 2 Q12107 P09798 affinity chromatography technology 12402045 physical association X 2 Q12107 P09798 affinity chromatography technology 15649358 physical association X 2 Q12107 P09798 affinity chromatography technology 15060174 physical association X 2 Q12107 P09798 affinity chromatography technology 9469814 physical association X 2 Q12107 P09798 affinity chromatography technology 16429126 physical association X 2 Q12107 P09798 affinity chromatography technology 16275330 physical association X 2 Q12107 P09798 affinity chromatography technology 17200106 physical association X 2 Q12107 P09798 affinity chromatography technology 17406682 physical association X 2 Q12107 P09798 affinity chromatography technology 15797379 physical association X 2 Q12107 P09798 affinity chromatography technology 21186364 physical association X 2 Q12107 P09798 affinity chromatography technology 16364911 physical association X 2 P14724 P09798 affinity chromatography technology 12574115 physical association X 2 P14724 P09798 affinity chromatography technology 10318877 physical association X 2 P14724 P09798 affinity chromatography technology 8895471 physical association X 2 P14724 P09798 affinity chromatography technology 8895471 physical association X 2 P14724 P09798 affinity chromatography technology 9348530 physical association X 2 P14724 P09798 affinity chromatography technology 15060174 physical association X 2 P14724 P09798 affinity chromatography technology 9469814 physical association X 2 P14724 P09798 affinity chromatography technology 16275330 physical association X 2 P14724 P09798 affinity chromatography technology 17406682 physical association X 2 P14724 P09798 affinity chromatography technology 15797379 physical association X 2 P14724 P09798 affinity chromatography technology 16364911 physical association X 2 Q04149 P09798 affinity chromatography technology 11805837 physical association X 2 P09798 P38042 affinity chromatography technology 12574115 physical association X 2 P09798 P16522 affinity chromatography technology 10318877 physical association X 2 P09798 P38042 affinity chromatography technology 10318877 physical association X 2 P09798 P38042 affinity chromatography technology 12609981 physical association X 2 P09798 P16522 affinity chromatography technology 12887895 physical association X 2 P09798 P38042 affinity chromatography technology 12887895 physical association X 2 P09798 P16522 affinity chromatography technology 8895471 physical association X 2 P09798 P16522 affinity chromatography technology 8895471 physical association X 2 P09798 P38042 affinity chromatography technology 8895471 physical association X 2 P09798 P38042 affinity chromatography technology 8895471 physical association X 2 P09798 P16522 affinity chromatography technology 7925276 physical association X 2 P09798 P38042 affinity chromatography technology 7925276 physical association X 2 P09798 P16522 affinity chromatography technology 12402045 physical association X 2 P09798 P16522 affinity chromatography technology 15649358 physical association X 2 P09798 P38042 affinity chromatography technology 12402045 physical association X 2 P09798 P38042 affinity chromatography technology 15649358 physical association X 2 P09798 P20486 affinity chromatography technology 10871279 physical association X 2 P09798 P16522 two hybrid 7925276 direct interaction X 2 P09798 P38042 two hybrid 7925276 direct interaction X 2 P09798 P38042 affinity chromatography technology 15060174 physical association X 2 P09798 P16522 affinity chromatography technology 15060174 physical association X 2 P09798 P38042 affinity chromatography technology 9469814 physical association X 2 P09798 P16522 affinity chromatography technology 9469814 physical association X 2 P09798 P00546 enzymatic study 10871279 direct interaction X 2 P09798 P16522 affinity chromatography technology 16481473 physical association X 2 P09798 P00546 enzymatic study 23751495 direct interaction X 2 P09798 P38042 affinity chromatography technology 23751495 physical association X 2 P09798 P16522 affinity chromatography technology 23751495 physical association X 2 P09798 P38042 affinity chromatography technology 16554755 physical association X 2 P09798 P16522 affinity chromatography technology 16554755 physical association X 2 P09798 P16522 affinity chromatography technology 16429126 physical association X 2 P09798 P16522 affinity chromatography technology 16429126 physical association X 2 P09798 P38042 affinity chromatography technology 16429126 physical association X 2 P09798 P38042 affinity chromatography technology 16275330 physical association X 2 P09798 P16522 affinity chromatography technology 16275330 physical association X 2 P09798 P16522 affinity chromatography technology 16481473 physical association X 2 P09798 P38042 affinity chromatography technology 17200106 physical association X 2 P09798 P16522 affinity chromatography technology 17200106 physical association X 2 P09798 P38042 affinity chromatography technology 17459880 physical association X 2 P09798 P38042 affinity chromatography technology 17406682 physical association X 2 P09798 P16522 affinity chromatography technology 17406682 physical association X 2 P09798 P38042 affinity chromatography technology 15797379 physical association X 2 P09798 P16522 affinity chromatography technology 15797379 physical association X 2 P09798 P38042 affinity chromatography technology 21186364 physical association X 2 P09798 P16522 affinity chromatography technology 21186364 physical association X 2 P09798 P38042 affinity chromatography technology 16364911 physical association X 2 P09798 P16522 affinity chromatography technology 16364911 physical association X 2 P15436 P09798 affinity chromatography technology 15649358 physical association X 2 P33299 P09798 affinity chromatography technology 11029046 physical association X 2 P53197 P09798 affinity chromatography technology 15916960 physical association X 2 P53197 P09798 affinity chromatography technology 25025567 physical association X 2 P53197 P09798 affinity chromatography technology 9831566 physical association X 2 Q12379 P09798 affinity chromatography technology 12574115 physical association X 2 Q12379 P09798 affinity chromatography technology 12574115 physical association X 2 Q12379 P09798 affinity chromatography technology 12609981 physical association X 2 Q12379 P09798 affinity chromatography technology 15060174 physical association X 2 Q12379 P09798 affinity chromatography technology 15060174 physical association X 2 Q12379 P09798 affinity chromatography technology 12477395 physical association X 2 Q12379 P09798 affinity chromatography technology 15649358 physical association X 2 Q12379 P09798 affinity chromatography technology 16275330 physical association X 2 Q12379 P09798 affinity chromatography technology 17406682 physical association X 2 Q12379 P09798 affinity chromatography technology 15797379 physical association X 2 Q12379 P09798 affinity chromatography technology 16364911 physical association X 2 Q08683 P09798 affinity chromatography technology 12574115 physical association X 2 Q08683 P09798 affinity chromatography technology 10318877 physical association X 2 Q08683 P09798 affinity chromatography technology 12887895 physical association X 2 Q08683 P09798 affinity chromatography technology 12402045 physical association X 2 Q08683 P09798 affinity chromatography technology 15649358 physical association X 2 Q08683 P09798 affinity chromatography technology 15060174 physical association X 2 Q08683 P09798 affinity chromatography technology 9469814 physical association X 2 Q08683 P09798 affinity chromatography technology 23751495 physical association X 2 Q08683 P09798 affinity chromatography technology 16429126 physical association X 2 Q08683 P09798 affinity chromatography technology 16429126 physical association X 2 Q08683 P09798 affinity chromatography technology 16275330 physical association X 2 Q08683 P09798 affinity chromatography technology 17200106 physical association X 2 Q08683 P09798 affinity chromatography technology 17406682 physical association X 2 Q08683 P09798 affinity chromatography technology 15797379 physical association X 2 Q08683 P09798 affinity chromatography technology 21186364 physical association X 2 Q08683 P09798 affinity chromatography technology 16364911 physical association X 2 Q04601 P09798 affinity chromatography technology 12574115 physical association X 2 P53068 P09798 affinity chromatography technology 12574115 physical association X 2 Q04601 P09798 affinity chromatography technology 10318877 physical association X 2 P53068 P09798 affinity chromatography technology 10318877 physical association X 2 P53068 P09798 affinity chromatography technology 10318877 physical association X 2 Q04601 P09798 affinity chromatography technology 12887895 physical association X 2 P53068 P09798 affinity chromatography technology 12887895 physical association X 2 Q04601 P09798 affinity chromatography technology 12402045 physical association X 2 Q04601 P09798 affinity chromatography technology 15649358 physical association X 2 P53068 P09798 affinity chromatography technology 12402045 physical association X 2 P53068 P09798 affinity chromatography technology 15649358 physical association X 2 Q04601 P09798 affinity chromatography technology 15060174 physical association X 2 Q04601 P09798 affinity chromatography technology 15060174 physical association X 2 P53068 P09798 affinity chromatography technology 15060174 physical association X 2 Q04601 P09798 affinity chromatography technology 9469814 physical association X 2 P53068 P09798 affinity chromatography technology 9469814 physical association X 2 Q04601 P09798 affinity chromatography technology 12477395 physical association X 2 Q04601 P09798 affinity chromatography technology 23751495 physical association X 2 P53068 P09798 affinity chromatography technology 16554755 physical association X 2 Q04601 P09798 affinity chromatography technology 16554755 physical association X 2 Q04601 P09798 affinity chromatography technology 16429126 physical association X 2 Q04601 P09798 affinity chromatography technology 16275330 physical association X 2 P53068 P09798 affinity chromatography technology 16275330 physical association X 2 Q04601 P09798 affinity chromatography technology 17200106 physical association X 2 P53068 P09798 affinity chromatography technology 17200106 physical association X 2 P53068 P09798 affinity chromatography technology 17406682 physical association X 2 Q04601 P09798 affinity chromatography technology 17406682 physical association X 2 Q04601 P09798 affinity chromatography technology 15797379 physical association X 2 P53068 P09798 affinity chromatography technology 15797379 physical association X 2 Q04601 P09798 affinity chromatography technology 21186364 physical association X 2 P53068 P09798 pull down 21186364 direct interaction X 2 Q04601 P09798 affinity chromatography technology 21186364 physical association X 2 P53068 P09798 affinity chromatography technology 21186364 physical association X 2 P53068 P09798 affinity chromatography technology 11805826 physical association X 2 Q04601 P09798 affinity chromatography technology 16364911 physical association X 2 P53068 P09798 affinity chromatography technology 16364911 physical association X 2 P09798 anti tag coimmunoprecipitation 11805837 - C 39 P09798 tandem affinity purification 11805826 - C 5 P09798 anti tag coimmunoprecipitation 11805837 - C 7 P09798 pull down 21107322 - C 13 P09798 tandem affinity purification 21107322 - C 12 P09798 tandem affinity purification 21107322 - C 13 P09798 inferred by author 11805826 physical association C 7 Q12440 P09798 tandem affinity purification 11805826 physical association X 2 Q12440 P09798 tandem affinity purification 21186364 physical association X 2 Q12440 P09798 tandem affinity purification 21107322 physical association X 2 Q12440 P09798 pull down 21107322 physical association X 2 Q12440 P09798 pull down 21107322 physical association X 2 Q12440 P09798 tandem affinity purification 21107322 physical association X 2 Q12440 P09798 coimmunoprecipitation 9469814 physical association X 2 Q12440 P09798 coimmunoprecipitation 9469815 physical association X 2 Q12157 P09798 coimmunoprecipitation 10888670 physical association X 2 Q12157 P09798 coimmunoprecipitation 10318877 physical association X 2 Q12157 P09798 pull down 21107322 physical association X 2 Q12157 P09798 coimmunoprecipitation 9469814 physical association X 2 Q12157 P09798 tandem affinity purification 21107322 physical association X 2 Q12157 P09798 tandem affinity purification 21186364 physical association X 2 Q12157 P09798 tandem affinity purification 21107322 physical association X 2 Q12157 P09798 tandem affinity purification 21186364 physical association X 2 Q12157 P09798 tandem affinity purification 21186364 physical association X 2 Q12157 P09798 pull down 21107322 physical association X 2 Q12157 P09798 anti tag coimmunoprecipitation 21186364 physical association X 2 P09798 P40577 tandem affinity purification 21107322 physical association X 2 P09798 P40577 pull down 21107322 physical association X 2 P09798 P40577 pull down 21107322 physical association X 2 P09798 P40577 tandem affinity purification 21107322 physical association X 2 P09798 P40577 tandem affinity purification 21186364 physical association X 2 P09798 P09798 two hybrid 7925276 physical association Y 1 P09798 P09798 coimmunoprecipitation 7925276 physical association Y 1 P09798 tandem affinity purification 21107322 physical association X 2 P09798 pull down 21107322 physical association X 2 P09798 coimmunoprecipitation 8895471 physical association X 2 P09798 tandem affinity purification 21107322 physical association X 2 P09798 tandem affinity purification 21186364 physical association X 2 P09798 tandem affinity purification 21186364 physical association X 2 P09798 tandem affinity purification 21186364 physical association X 2 P09798 coimmunoprecipitation 9469814 physical association X 2 P09798 pull down 21107322 physical association X 2 P09798 coimmunoprecipitation 9469814 physical association X 2 P09798 tandem affinity purification 21107322 physical association X 2 P09798 tandem affinity purification 21186364 physical association X 2 P09798 cross-linking study 21186364 physical association X 2 P09798 coimmunoprecipitation 10318877 physical association X 2 P09798 pull down 21107322 physical association X 2 P09798 cross-linking study 21186364 physical association X 2 P09798 tandem affinity purification 11805826 physical association X 2 P09798 cross-linking study 21186364 physical association X 2 P09798 P33301 anti tag coimmunoprecipitation 11805837 physical association X 2 P09798 P50082 coimmunoprecipitation 11114178 physical association X 2 Q12107 P09798 coimmunoprecipitation 9469814 physical association X 2 Q12107 P09798 tandem affinity purification 21186364 physical association X 2 Q12107 P09798 coimmunoprecipitation 10318877 physical association X 2 Q12107 P09798 tandem affinity purification 21107322 physical association X 2 Q12107 P09798 tandem affinity purification 21107322 physical association X 2 Q12107 P09798 pull down 21107322 physical association X 2 Q12107 P09798 pull down 21107322 physical association X 2 P14724 P09798 cosedimentation through density gradient 8895471 physical association X 2 P14724 P09798 coimmunoprecipitation 8895471 physical association X 2 P14724 P09798 coimmunoprecipitation 9469814 physical association X 2 P14724 P09798 tandem affinity purification 21107322 physical association X 2 P14724 P09798 tandem affinity purification 21107322 physical association X 2 P14724 P09798 pull down 21107322 physical association X 2 P14724 P09798 pull down 21107322 physical association X 2 P09798 anti tag coimmunoprecipitation 11805837 - C 6 P09798 tandem affinity purification 11805826 - C 5 P09798 anti tag coimmunoprecipitation 11805837 - C 26 P09798 tandem affinity purification 21186364 - C 3 P09798 tandem affinity purification 21186364 - C 3 P09798 electron tomography 21186364 physical association C 11 P09798 tandem affinity purification 21186364 physical association C 11 P09798 pull down 21107322 - C 14 P09798 anti tag coimmunoprecipitation 21186364 - C 3 Q04149 P09798 anti tag coimmunoprecipitation 11805837 physical association X 2 P09798 P16522 tandem affinity purification 21107322 physical association X 2 P09798 P16522 pull down 21107322 physical association X 2 P09798 P16522 tandem affinity purification 21107322 physical association X 2 P09798 P16522 pull down 21107322 physical association X 2 P09798 P16522 two hybrid 7925276 physical association X 2 P09798 P16522 coimmunoprecipitation 7925276 physical association X 2 P09798 P16522 coimmunoprecipitation 8895471 physical association X 2 P09798 P16522 anti tag coimmunoprecipitation 21186364 physical association X 2 P09798 P16522 coimmunoprecipitation 9469814 physical association X 2 P09798 P16522 tandem affinity purification 21186364 physical association X 2 P09798 P38042 tandem affinity purification 21107322 physical association X 2 P09798 P38042 two hybrid 7925276 physical association X 2 P09798 P38042 coimmunoprecipitation 7925276 physical association X 2 P09798 P38042 coimmunoprecipitation 7925276 physical association X 2 P09798 P38042 tandem affinity purification 21107322 physical association X 2 P09798 P38042 coimmunoprecipitation 8895471 physical association X 2 P09798 P38042 pull down 21107322 physical association X 2 P09798 P38042 coimmunoprecipitation 9469814 physical association X 2 P09798 P38042 pull down 21107322 physical association X 2 P09798 P38042 tandem affinity purification 21186364 physical association X 2 P53197 P09798 coimmunoprecipitation 9831566 physical association X 2 P53197 P09798 pull down 21107322 physical association X 2 P53197 P09798 pull down 21107322 physical association X 2 Q12379 P09798 pull down 21107322 physical association X 2 Q12379 P09798 pull down 21107322 physical association X 2 Q12379 P09798 tandem affinity purification 21107322 physical association X 2 Q12379 P09798 tandem affinity purification 21107322 physical association X 2 Q08683 P09798 coimmunoprecipitation 9469814 physical association X 2 Q08683 P09798 tandem affinity purification 21107322 physical association X 2 Q08683 P09798 pull down 21107322 physical association X 2 Q08683 P09798 pull down 21107322 physical association X 2 Q08683 P09798 tandem affinity purification 21186364 physical association X 2 Q08683 P09798 tandem affinity purification 21107322 physical association X 2 Q08683 P09798 coimmunoprecipitation 10318877 physical association X 2 Q04601 P09798 tandem affinity purification 21186364 physical association X 2 Q04601 P09798 tandem affinity purification 21107322 physical association X 2 Q04601 P09798 tandem affinity purification 21107322 physical association X 2 Q04601 P09798 pull down 21107322 physical association X 2 Q04601 P09798 pull down 21107322 physical association X 2 P09798 anti tag coimmunoprecipitation 9469814 association C 9 P09798 anti tag coimmunoprecipitation 9469814 association C 9 P09798 anti tag coimmunoprecipitation 9469814 association C 9 P09798 anti tag coimmunoprecipitation 9469814 association C 9 P09798 anti tag coimmunoprecipitation 9469814 association C 9 P09798 tandem affinity purification 16429126 association C 22 P09798 tandem affinity purification 16429126 association C 6 P09798 affinity chromatography technology 12609981 association C 11 P09798 affinity chromatography technology 12609981 association C 11 P09798 inferred by author 16554755 association C 12 P09798 tandem affinity purification 12477395 association C 13 P09798 tandem affinity purification 12477395 association C 13 P09798 tandem affinity purification 12477395 association C 13 P09798 affinity chromatography technology 12609981 association C 13 P09798 anti tag coimmunoprecipitation 9469814 association C 7 P09798 tandem affinity purification 11805826 association C 5 P09798 tandem affinity purification 16429126 association C 5 P09798 anti tag coimmunoprecipitation 9469814 association C 10 P09798 anti tag coimmunoprecipitation 9469814 association C 10 P09798 anti tag coimmunoprecipitation 9469814 association C 10 P09798 anti tag coimmunoprecipitation 9469814 association C 12 P09798 anti tag coimmunoprecipitation 9469814 association C 12 P09798 anti tag coimmunoprecipitation 9469814 association C 12 P09798 anti tag coimmunoprecipitation 9469814 association C 12 P09798 anti tag coimmunoprecipitation 9469814 association C 12 P09798 anti tag coimmunoprecipitation 11805837 association C 32 Q12440 P09798 tandem affinity purification 16554755 physical association X 2 Q12440 P09798 tandem affinity purification 16554755 physical association X 2 Q12440 P09798 tandem affinity purification 16554755 physical association X 2 Q12440 P09798 tandem affinity purification 16554755 physical association X 2 P46988 P09798 tandem affinity purification 19536198 association X 2 P09798 P50082 anti tag coimmunoprecipitation 11114178 physical association X 2 P09798 anti tag coimmunoprecipitation 11805837 association C 7 P09798 tandem affinity purification 11805826 association C 6 P09798 tandem affinity purification 16429126 association C 6 P09798 tandem affinity purification 16429126 association C 19 P09798 inferred by author 16429126 physical association C 9 P09798 anti tag coimmunoprecipitation 9469814 association C 8 P09798 anti tag coimmunoprecipitation 9469814 association C 8 P09798 anti tag coimmunoprecipitation 9469814 association C 7 P09798 anti tag coimmunoprecipitation 9469814 association C 7 P32589 P09798 tandem affinity purification 19536198 association X 2 P11484 P09798 tandem affinity purification 19536198 association X 2 P09798 P16522 tandem affinity purification 16554755 physical association X 2 P09798 P38042 tandem affinity purification 16554755 physical association X 2 P09798 P38042 tandem affinity purification 16554755 physical association X 2 P09798 P39987 tandem affinity purification 19536198 association X 2 P10591 P09798 tandem affinity purification 19536198 association X 2 Q04601 P09798 tandem affinity purification 16554755 physical association X 2 P53068 P09798 tandem affinity purification 16554755 physical association X 2 P53068 P09798 tandem affinity purification 16554755 physical association X 2 P53068 P09798 tandem affinity purification 16554755 physical association X 2 P53068 P09798 tandem affinity purification 16554755 physical association X 2 P53068 P09798 miniaturized immunoprecipitation 23267104 direct interaction X 2 P09798 mass spectrometry studies of complexes 11805826 - C 8 P09798 mass spectrometry studies of complexes 11805837 - C 27 Q12440 P09798 coimmunoprecipitation 9469814,9469815 - X 2 Q12440 P09798 coimmunoprecipitation 9469814,9469815 - X 2 Q12157 P09798 coimmunoprecipitation 9469814 - X 2 P53886 P09798 coimmunoprecipitation 9469814 - X 2 P53886 P09798 coimmunoprecipitation 8895471,9469814 - X 2 Q12107 P09798 coimmunoprecipitation 9469814 - X 2 P14724 P09798 interaction detection method 9348530 - X 2 P14724 P09798 coimmunoprecipitation 8895471,9469814 - X 2 P09798 mass spectrometry studies of complexes 11805837 - C 7 P09798 confirmational text mining - - C 11 P38826 P09798 interaction detection method - - X 2 P09798 P16522 two hybrid 7925276,9469814 - X 2 P09798 P16522 coimmunoprecipitation 9469814 - X 2 P09798 P38042 two hybrid 7925276 - X 2 P09798 P38042 coimmunoprecipitation 9469814 - X 2 Q08683 P09798 coimmunoprecipitation 9469814 - X 2 Q04601 P09798 coimmunoprecipitation 9469814 - X 2 P53068 P09798 coimmunoprecipitation 9469814 - X 2

PPI - HINT Gene A Gene B PMID Method Quality CDC28 CDC16 23751495,10871279 0415,0415 LC CDC16 CDC16 7925276,7925276 0019,0018 LC CDC16 CDC26 9348530,9348530,8895471,9469814,8895471,8895471,9469814,9469814 0004,0019,0019,0004,0029,0004,0019,0007 LC CDC16 CDC23 7925276,9469814,7925276,7925276,9469814,9469814,8895471,8895471,9469814 0019,0018,0018,0004,0004,0019,0019,0004,0007 LC CDC16 PPH21 23751495 0415 LC CDC16 PPH22 23751495 0415 LC CDC16 CDC5 10871279 0415 LC CDC16 CDC27 7925276,7925276,7925276,9469814,9469814,8895471,8895471,9469814 0019,0018,0004,0004,0019,0019,0004,0007 LC CDC16 PDS1 16364911 0415 LC CDC16 AMA1 11114178,11114178,11114178 0007,0004,0019 LC CDC16 DOC1 21186364,21186364,9469814,9469814,10318877,23267104,10318877,21186364,21186364,9469814 0096,0676,0004,0019,0019,0946,0004,0004,0030,0007 LC CDC16 CDH1 9831566,9831566 0004,0019 LC CDC16 APC1 9469814,9469814,8895471,8895471,9469814 0004,0019,0019,0004,0007 LC CDC16 APC4 9469814,9469814,9469814 0004,0019,0007 LC CDC16 APC5 9469814,9469814,10318877,10318877,9469814 0004,0019,0019,0004,0007 LC CDC16 APC9 9469814,9469814,10318877,10318877,9469814 0004,0019,0019,0004,0007 LC CDC16 APC11 10888670,9469814,10888670,10318877,9469814,10318877,9469814 0019,0004,0004,0004,0019,0019,0007 LC CDC16 APC2 9469815,9469814,9469814,9469815,9469814 0019,0004,0019,0004,0007 LC CDC19 CDC16 16429126 0676 HT TUB2 CDC16 16429126 0676 HT TEF1|TEF2 CDC16 16429126 0676 HT PDC1 CDC16 16429126 0676 HT FAS1 CDC16 16429126 0676 HT URA2 CDC16 16429126 0676 HT TUB1 CDC16 16429126 0676 HT CDC16 CDC16 21186364,9469814,15060174 0004,0004,0004 LC CDC16 SSA1 19536198 0676 HT CDC16 SSA2 16429126 0676 HT CDC16 SSB1 19536198,16429126 0676,0676 HT CDC16 CDC26 9348530,9348530,8895471,21107322,15060174,17406682,16364911,9469814,8895471,8895471,10318877,21107322,12574115,9469814,15797379,16275330,9469814 0004,0019,0019,0096,0004,0004,0004,0004,0029,0004,0004,0676,0004,0019,0004,0004,0007 LC CDC16 POL3 15649358 0004 LC CDC16 VMA2 16429126 0676 HT CDC16 YEF3 16429126,16429126 0676,0004 HT CDC16 CDC23 7925276,23751495,17406682,21186364,21107322,16481473,17200106,9469814,7925276,7925276,9469814,12887895,12402045,9469814,15797379,8895471,16554755,21107322,16429126,10318877,15649358,8895471,16554755,15060174,16429126,21186364,16275330,16364911,9469814,21186364 0019,0004,0004,0676,0096,0004,0004,0018,0018,0004,0004,0004,0004,0019,0004,0019,0676,0676,0676,0004,0004,0004,0004,0004,0004,0004,0004,0004,0007,0007 LC,HT CDC16 CKS1 10871279 0004 LC CDC16 CDC20 22940250,21118994,12887895 0096,0004,0004 LC CDC16 RPL5 16429126 0676 HT CDC16 SSE1 19536198 0676 HT CDC16 RPT1 11029046 0004 LC CDC16 XRS2 11805837,11805837 0004,0007 HT CDC16 SPT21 25228766 0004 HT CDC16 CDC27 7925276,23751495,17406682,17459880,21186364,12609981,21107322,12574115,17200106,7925276,7925276,9469814,12887895,12402045,9469814,15797379,8895471,16554755,21107322,16429126,10318877,15649358,8895471,16554755,15060174,16429126,21186364,16275330,16364911,9469814 0019,0004,0004,0004,0676,0004,0096,0004,0004,0018,0004,0004,0004,0004,0019,0004,0019,0676,0676,0676,0004,0004,0004,0004,0004,0004,0004,0004,0004,0007 LC,HT CDC16 AIM4 21386897 0004 LC CDC16 ECM10 19536198 0676 HT CDC16 MND2 12477395,12609981,12477395,17406682,16364911,15060174,21186364,21186364,21107322,21107322,15649358,12574115,16275330,15797379 0676,0004,0004,0004,0004,0004,0004,0676,0096,0676,0004,0004,0004,0004 LC CDC16 PSA1 16429126 0676 HT CDC16 PFD1 19536198 0676 HT CDC16 RPL4B 16429126 0676 HT CDC16 AMA1 11114178,11114178,11114178 0007,0004,0019 LC CDC16 DOC1 17406682,21186364,21186364,21107322,12574115,17200106,9469814,12887895,12402045,9469814,10318877,15797379,16554755,16554755,21107322,16429126,11805826,10318877,15649358,16554755,15060174,16364911,11805826,21186364,16275330,11805826,21186364,9469814 0004,0096,0676,0096,0004,0004,0004,0004,0004,0019,0019,0004,0363,0676,0676,0676,0004,0004,0004,0004,0004,0004,0676,0004,0004,0007,0030,0007 LC,HT CDC16 CDH1 9831566,21107322,21107322,25025567,15916960,9831566 0004,0004,0096,0004,0004,0019 LC CDC16 APC1 23751495,17406682,21186364,21107322,16481473,12574115,17200106,9469814,12887895,12402045,9469814,15797379,8895471,21107322,16429126,10318877,15649358,8895471,15060174,16429126,21186364,16275330,16429126,16364911,9469814 0004,0004,0676,0096,0004,0004,0004,0004,0004,0004,0019,0004,0019,0676,0676,0004,0004,0004,0004,0004,0004,0004,0363,0004,0007 LC,HT CDC16 MUS81 11805837,11805837 0004,0007 HT CDC16 APC4 12477395,23751495,17406682,21186364,21107322,12574115,17200106,9469814,12887895,12402045,9469814,15797379,16554755,21107322,16429126,10318877,15649358,12477395,16554755,15060174,16429126,21186364,16275330,16364911,9469814 0676,0004,0004,0676,0096,0004,0004,0004,0004,0004,0019,0004,0676,0676,0676,0004,0004,0004,0004,0004,0004,0004,0004,0004,0007 LC,HT CDC16 URN1 21386897 0004 LC CDC16 APC5 23751495,17406682,15649358,21107322,12574115,17200106,9469814,12887895,12402045,9469814,10318877,15797379,21107322,16429126,10318877,21186364,15060174,16429126,21186364,16275330,16364911,9469814 0004,0004,0004,0096,0004,0004,0004,0004,0004,0019,0019,0004,0676,0676,0004,0676,0004,0004,0004,0004,0004,0007 LC,HT CDC16 APC9 17406682,15649358,21107322,12574115,17200106,9469814,12887895,12402045,9469814,10318877,15797379,21107322,16429126,10318877,21186364,15060174,16429126,21186364,16275330,16364911,9469814 0004,0004,0096,0004,0004,0004,0004,0004,0019,0019,0004,0676,0676,0004,0676,0004,0004,0004,0004,0004,0007 LC,HT CDC16 APC11 21107322,10888670,21107322,9469814,17406682,16364911,15060174,21186364,10888670,21186364,21186364,10318877,12574115,15649358,9469814,10318877,16275330,9469814,15797379 0676,0019,0096,0004,0004,0004,0004,0004,0004,0676,0007,0004,0004,0004,0019,0019,0004,0007,0004 LC CDC16 SWM1 12477395,12609981,12477395,17406682,16364911,15060174,21107322,21107322,15649358,12574115,16275330,15797379,9469814 0676,0004,0004,0004,0004,0004,0096,0676,0004,0004,0004,0004,0007 LC CDC16 APC2 23751495,17406682,21186364,21107322,12574115,17200106,9469815,9469814,12887895,12402045,9469814,9469815,15797379,16554755,21107322,16429126,11805826,10318877,15649358,16554755,15060174,16429126,11805826,21186364,16275330,11805826,16364911,9469814 0004,0004,0676,0096,0004,0004,0019,0004,0004,0004,0019,0004,0004,0676,0676,0676,0004,0004,0004,0004,0004,0004,0676,0004,0004,0007,0004,0007 LC,HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53197 P09798 CDH1 CDC16 0.49 9831566,15916960,25025567 P23594 P09798 PPH21 CDC16 0.309 23751495 P23595 P09798 PPH22 CDC16 0.309 23751495 Q12060 P09798 HFI1 CDC16 0.21 27647735 P10591 P09798 SSA1 CDC16 0.126 19536198 P09798 P02557 CDC16 TUB2 0.126 16429126 P09798 P00549 CDC16 CDC19 0.126 16429126 P09798 P06169 CDC16 PDC1 0.126 16429126 P09798 P02994 CDC16 TEF2 0.126 16429126 P50082 P09798 AMA1 CDC16 0.033 11114178 P09798 P09733 CDC16 TUB1 0.126 16429126 P09798 P07259 CDC16 URA2 0.126 16429126 P09798 P07149 CDC16 FAS1 0.126 16429126 P10592 P09798 SSA2 CDC16 0.126 16429126 P11484 P09798 SSB1 CDC16 0.236 16429126,19536198 P16521 P09798 YEF3 CDC16 0.126 16429126 P49626 P09798 RPL4B CDC16 0.126 16429126 P15436 P09798 POL3 CDC16 0.21 15649358 P16140 P09798 VMA2 CDC16 0.126 16429126 P41940 P09798 PSA1 CDC16 0.126 16429126 P32589 P09798 SSE1 CDC16 0.126 19536198 P26321 P09798 RPL5 CDC16 0.126 16429126 Q04149 P09798 MUS81 CDC16 0.332 11805837 P09798 P00546 CDC16 CDC28 0.309 23751495 P09798 P09798 CDC16 CDC16 0.354 21186364,9469814,7925276 Q08683 P09798 APC5 CDC16 0.843 16275330,17406682,16429126,9469814,15797379,21186364,16364911,10318877,23751495 Q12107 P09798 APC9 CDC16 0.808 16275330,17406682,16429126,9469814,15797379,21186364,16364911,10318877 Q12157 P09798 APC11 CDC16 0.872 16275330,17406682,15649358,9469814,15797379,21186364,16364911,10888670,10318877 Q12379 P09798 SWM1 CDC16 0.794 16275330,17406682,15649358,12477395,9469814,15797379,16364911 P40577 P09798 MND2 CDC16 0.814 16275330,17406682,15649358,12477395,15797379,21186364,16364911 P53886 P09798 APC1 CDC16 0.899 16275330,17406682,16429126,9469814,16481473,15797379,21186364,8895471,16364911,23751495 P53068 P09798 DOC1 CDC16 0.934 16275330,23267104,17406682,16554755,9469814,15797379,21186364,16364911,10318877,11805826,16429126 Q12440 P09798 APC2 CDC16 0.945 16275330,17406682,16554755,9469814,15797379,21186364,9469815,16364911,23751495,11805826,16429126 P16522 P09798 CDC23 CDC16 0.908 16275330,17406682,16554755,9469814,16481473,15797379,21186364,8895471,16364911,23751495,16429126,7925276 P38042 P09798 CDC27 CDC16 0.925 16275330,17406682,16554755,9469814,15797379,21186364,8895471,16364911,23751495,17459880,16429126,7925276 Q04601 P09798 APC4 CDC16 0.934 16275330,17406682,16429126,12477395,16554755,9469814,15797379,21186364,16364911,23751495 P35209 P09798 SPT21 CDC16 0.126 25228766 P26309 P09798 CDC20 CDC16 0.454 21118994,22940250 P38305 P09798 AIM4 CDC16 0.126 21386897 P33301 P09798 XRS2 CDC16 0.286 11805837 P39987 P09798 ECM10 CDC16 0.126 19536198 P46988 P09798 PFD1 CDC16 0.126 19536198 P14724 P09798 CDC26 CDC16 0.74 16275330,17406682,9469814,15797379,8895471,16364911 Q06525 P09798 URN1 CDC16 0.126 21386897