PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RPL40A CCR4 i2d exp RPL40A POL2 i2d exp RPL40A GND1 16284124,20080635 intact,dip exp RPL40A HSE1 12055639 dip exp RPL40A YUH1 i2d exp RPL40A KAP95 i2d exp RPL40A DHH1 i2d exp RPL40A RAD17 18485869 intact exp RPL40A SAW1 i2d exp RPL40A SKP2 11805837 intact,dip exp RPL40A UFD4 i2d exp RPL40A SBP1 i2d exp RPL40A DDI1 11323716 dip exp RPL40A CYB5 16554755 i2d,intact exp RPL40A HIF1 i2d exp RPL40A MUS81 11805837 intact,dip exp RPL40A CPR1 21179020 intact exp RPL40A SWE1 i2d exp RPL40A DSK2 11805121 i2d,dip exp RPL40A EDE1 16007098 dip exp RPL40A NUP42 i2d exp RPL40A YEF3 i2d exp RPL40A HRT3 11805837 intact,dip exp RPL40A BBC1 i2d exp RPL40A CCT6 i2d exp RPL40A HYP2 i2d exp RPL40A UFD2 10089879,11805837 intact,dip exp RPL40A MET4 10975521 i2d,dip exp RPL40A MET30 11805837 intact,dip exp RPL40A ACC1 i2d exp RPL40A PH domain-containing protein YHR131C i2d exp RPL40A Putative proline--tRNA ligase YHR020W i2d exp RPL40A AHA1 i2d exp RPL40A CLN1 10213692 dip exp RPL40A GRR1 11805837 intact,dip exp RPL40A GCN5 14660704 intact exp SEM1 RPL40A i2d exp RPL40A NOP14 i2d exp RPL40A GSC2 i2d exp RPL40A SHM2 i2d exp RPL40A SMT3 i2d exp RPL40A CDC48 11733065 dip exp RPL40A THG1 14690591 intact exp RPL40A PWWP domain-containing protein YLR455W i2d exp RPL40A SIC1 9334303 dip exp RPL40A PSF2 14690591 intact exp RPL40A MGT1 19164530 dip exp RPL40A POL3 24465179 dip exp RPL40A DPH1 i2d exp RPL40A SAN1 11805837 intact,dip exp RPL40A Uncharacterized WD repeat-containing protein YOL087C 11805837 intact,dip exp GPA1 RPL40A 11955054 dip exp RPL40A UBX5 16007098,18719252 intact,dip exp RPL40A SSA2 i2d exp RPL40A GTT2 i2d exp RPL40A CLB2 8744951 dip exp RPL40A IFA38 i2d exp RPL40A ASC1 i2d exp RPL40A VPS28 11511343 dip exp RPL40A SGF73 i2d exp RPL40A UBA1 1989885,18662542 i2d,intact,dip exp RPL40A POL1 i2d exp RPL40A PAN1 i2d exp RPL40A SAR1 i2d exp RPL40A END3 i2d exp RPL40A RAD50 i2d exp RPL40A EGD2 16926149 intact exp RPL40A CUE5 i2d exp RPL40A ETR1 i2d exp RPL40A CMK1 i2d exp HXK2 RPL40A i2d exp RPL40A RAD23 10688190,11323716 i2d,intact,dip exp RPL40A CUE2 i2d exp RPL40A UBX2 16007098 dip exp RPL40A Uncharacterized protein YDR179W-A i2d exp RPL40A RPL40A 21807993 dip exp RPL40A SWD1 11805837 intact,dip exp RPL40A AKL1 i2d exp RPL40A STP22 11511343 i2d,dip exp ILV1 RPL40A i2d exp RPL40A CDC34 12861024 i2d,dip exp RPL40A ACF4 i2d exp RPL40A BMH2 i2d exp RPL40A TSR3 i2d exp RPL40A DBP5 i2d exp RPL40A TGL5 i2d exp RPL40A ATG1 i2d exp PRC1 RPL40A 20080635 dip exp RPL40A Uncharacterized transporter YHL008C i2d exp RPL40A RVS167 11805837 i2d,intact,dip exp RPL40A GPD1 i2d exp RPL40A GFA1 i2d exp RPL40A BAP3 i2d exp GAL80 RPL40A 22479149 dip exp RPL40A CBF5 i2d exp RPL40A STE6 18191224 intact exp RPL40A ALY2 i2d exp RPL40A RUP1 16007098 dip exp RPL40A HSC82 15766533 i2d,intact exp RPL40A PSE1 i2d exp RPL40A SHP1 16007098 dip exp RPL40A DCN1 i2d exp RPL40A HRT1 11805837 intact,dip exp RPL40A PDC6 i2d exp RPL40A UBC1 18662542,16007098 i2d,intact,dip exp RPL40A RRP6 i2d exp RPL40A LSB5 15651983 intact exp RPL40A CPS1 11511343 dip exp RPL40A GPD2 i2d exp RPL40A SSA1 i2d exp RPL40A UBP14 16007098 i2d,dip exp RPL40A BRE5 i2d exp RPL40A MMS22 i2d exp RPL40A LSP1 i2d exp RPL40A CAJ1 i2d exp RPL40A TIF4631 i2d exp TPK1 RPL40A i2d exp RPL40A RPA49 i2d exp RPL40A OLE1 i2d exp RPL40A YTH1 i2d exp RPL40A SEC15 i2d exp NOT3 RPL40A i2d exp RPL40A GDS1 i2d exp RPL40A TOM1 i2d exp RPL40A POL30 20453836 dip exp RPL40A RIX7 14690591 intact exp RPL40A NPA3 i2d exp RPL40A HSP42 i2d exp RPL40A URN1 16606443 intact exp RPL40A KSS1 11805837 intact,dip exp SNF1 RPL40A 11805837 intact,dip exp RAD1 RPL40A 11805837 intact,dip exp CDC7 RPL40A 11805837 intact,dip exp RPL40A PIB1 11805837 intact,dip exp RPL40A CSR1 i2d exp RPL40A SSB1 i2d exp RPL40A DOA1 i2d exp RPL40A WTM1 i2d exp RPL40A GTS1 16007098 dip exp RPL40A RPT6 i2d exp RPL40A PGI1 i2d exp HTA1 RPL40A i2d exp TDH1 RPL40A i2d exp RPL40A NAT5 i2d exp RPL40A RPS10B i2d exp RPL40A EGT2 11283351 i2d,intact,dip exp RPL40A PRP8 18425143 dip exp RPL40A PFK1 i2d exp RPL40A PMT1 i2d exp RPL40A UBC7 14690591,11805837 intact,dip exp RPL40A VMA5 i2d exp RPL40A TIF1, TIF2 i2d exp SWI5 RPL40A 18787112 dip exp RPL40A PIN3 11743162 i2d,intact,dip exp RPL40A RVS161 i2d exp RAD7 RPL40A 11805837 intact,dip exp RPL40A VPS1 i2d exp RPL40A PHO85 i2d exp RPL40A WWM1 16606443 intact exp RPL40A VPS27 12055639 dip exp RPL40A PCA1 19515821 dip exp RPL40A RAD4 10688190 i2d,dip exp

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P0CH08 P25604 - 15044434 - X 2 P0CH08 - 12970172 - X 2 P0CH08 - 12628920,12787502 - X 2 P0CH08 - 12628920,12787502 - X 2 P0CH08 - 15766533 - X 2 P21734 P0CH08 - 11591345 - X 2 P21734 P0CH08 - 11591345 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P15108 - 15766533 - X 2 P0CH08 Q12449 - 15766533 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P35127 - 10406793,9233788 - X 2 P0CH08 P11484 - 15766533 - X 2 P0CH08 - 12787503 - X 2 P0CH08 P10592 - 15766533 - X 2 P14682 P0CH08 affinity chromatography technology 16554755 physical association X 2 P38071 P0CH08 affinity chromatography technology 16554755 physical association X 2 P0CH08 Q12306 protein complementation assay 23403034 direct interaction X 2 P0CH08 P02829 affinity chromatography technology 15766533 physical association X 2 P0CH08 P40693 affinity chromatography technology 23945946 physical association X 2 P0CH08 P40693 affinity chromatography technology 23945946 physical association X 2 P0CH08 P25037 enzymatic study 2050695 direct interaction X 2 P0CH08 P25037 enzymatic study 2050695 direct interaction X 2 P0CH08 Q01476 enzymatic study 1429680 direct interaction X 2 P0CH08 Q01477 enzymatic study 1429680 direct interaction X 2 P0CH08 P25037 enzymatic study 1429680 direct interaction X 2 P0CH08 P43558 affinity chromatography technology 22902402 physical association X 2 P0CH08 P38080 affinity chromatography technology 16554755 physical association X 2 P0CH08 P04806 affinity chromatography technology 16554755 physical association X 2 P0CH08 P06102 affinity chromatography technology 16554755 physical association X 2 P0CH08 P10081 affinity chromatography technology 16554755 physical association X 2 P0CH08 P14742 affinity chromatography technology 16554755 physical association X 2 P0CH08 Q06142 affinity chromatography technology 16554755 physical association X 2 P0CH08 P40312 affinity chromatography technology 16554755 physical association X 2 P0CH08 Q12390 affinity chromatography technology 16554755 physical association X 2 P0CH08 Q12043 affinity chromatography technology 16554755 physical association X 2 P0CH08 P38080 enzymatic study 16319894 direct interaction X 2 P0CH08 P53104 enzymatic study 16319894 direct interaction X 2 P0CH08 P32944 enzymatic study 16319894 direct interaction X 2 P0CH08 P32944 enzymatic study 16319894 direct interaction X 2 P0CH08 P23291 enzymatic study 16319894 direct interaction X 2 P0CH08 Q12306 affinity chromatography technology 15166219 physical association X 2 P0CH08 P17157 enzymatic study 16319894 direct interaction X 2 P0CH08 P38305 affinity chromatography technology 21386897 physical association X 2 P0CG63 P0CH08 affinity chromatography technology 23749301 physical association X 2 P0CG63 P0CH08 affinity chromatography technology 17644757 physical association X 2 P0CG63 P0CH08 affinity chromatography technology 17644757 physical association X 2 P0CG63 P0CH08 affinity chromatography technology 21427232 physical association X 2 P0CG63 P0CH08 affinity chromatography technology 21427232 physical association X 2 P0CG63 P0CH08 affinity chromatography technology 22106047 physical association X 2 P0CX84 P0CH08 affinity chromatography technology 22995916 physical association X 2 P0CX84 P0CH08 affinity chromatography technology 22995916 physical association X 2 Q03280 P0CH08 affinity chromatography technology 16554755 physical association X 2 P27466 P0CH08 enzymatic study 16319894 direct interaction X 2 P27466 P0CH08 enzymatic study 16319894 direct interaction X 2 P38237 P0CH08 affinity chromatography technology 16554755 physical association X 2 Q12373 P0CH08 affinity chromatography technology 16554755 physical association X 2 P21576 P0CH08 affinity chromatography technology 16554755 physical association X 2 P0CH08 P0CX43 affinity chromatography technology 22995916 physical association X 2 P0CH08 P0CX43 affinity chromatography technology 22995916 physical association X 2 P0CH08 P05317 affinity chromatography technology 22995916 physical association X 2 P0CH08 P05317 affinity chromatography technology 22995916 physical association X 2 P0CH08 P35127 enzymatic study 1429680 direct interaction X 2 P0CH08 P40150 biochemical 23332755 association X 2 P0CH08 P04912 affinity chromatography technology 16554755 physical association X 2 P0CH08 P32628 affinity chromatography technology 16554755 physical association X 2 P0CH08 P0CX57 affinity chromatography technology 16554755 physical association X 2 P0CH08 P25343 affinity chromatography technology 16554755 physical association X 2 P0CH08 P39517 affinity chromatography technology 16554755 physical association X 2 P0CH08 P39743 affinity chromatography technology 16554755 physical association X 2 P0CH08 P23301 affinity chromatography technology 16554755 physical association X 2 P0CH08 P01123 affinity chromatography technology 16554755 physical association X 2 P0CH08 P31412 affinity chromatography technology 16554755 physical association X 2 P0CH08 P15108 affinity chromatography technology 16554755 physical association X 2 P0CH08 P39013 affinity chromatography technology 16554755 physical association X 2 P0CH08 Q08412 affinity chromatography technology 16554755 physical association X 2 P0CH08 P33202 affinity chromatography technology 16554755 physical association X 2 P0CH08 P06244 enzymatic study 16319894 direct interaction X 2 P0CH08 P40568 affinity chromatography technology 21107429 physical association X 2 P0CH08 Q06525 affinity chromatography technology 21386897 physical association X 2 P47068 P0CH08 affinity chromatography technology 16554755 physical association X 2 P0CH08 inferred by author 16554755 association C 7 P0CH08 P15108 affinity chromatography technology 15766533 physical association X 2 P0CH08 Q06682 two hybrid 18719252 physical association X 2 P0CH08 confirmational text mining - - C 81 P0CH08 confirmational text mining - - C 81 P0CH08 P40395 interaction detection method 14764870 - X 2

PPI - HINT Gene A Gene B PMID Method Quality TPK1 RPL40B 16319894 0415 LC RPL40B PHO85 16319894 0415 LC RPL40B UBC1 18662542 0404 LC RPL40B UBA1 18662542,18662542 0404,0114 LC RPL40B YCK1 16319894 0415 LC RPL40B UBP1 2050695,1429680 0415,0415 LC RPL40B CMK1 16319894 0415 LC RPL40B RAD23 10688190 0018 HT RPL40B SWE1 16319894 0415 LC RPL40B YUH1 1429680 0415 LC RPL40B AKL1 16319894 0415 LC RPL40B EGD2 16926149 0415 LC RPL40B SSB2 23332755 0401 LC RPL40B EGT2 11283351 0399 HT RPL40B WWM1 16606443 0089 HT RPL40B ATG1 16319894 0415 LC RPL40B THG1 14690591 0397 LC RPL40B UBP2 1429680 0415 LC RPL40B UBP3 1429680 0415 LC RPL40B UBC7 14690591 0397 LC RPL40B PIN3 11743162 0018 HT RPL40B URN1 16606443 0089 HT RPL40B UBX5 18719252 0018 HT RPL40B SMT3 23403034 0090 HT YPT1 RPL40B 16554755 0004 HT HSP82 RPL40B 15766533 0004 LC COX4 RPL40B 23864706 0004 LC HXK1 RPL40B 16554755 0004 HT HTA2 RPL40B 16554755 0004 HT RPP0 RPL40B 22995916 0004 LC NOT3 RPL40B 16554755 0004 HT CDC7 RPL40B 11805837 0007 HT RAD1 RPL40B 11805837 0007 HT RAD7 RPL40B 11805837 0007 HT SNF1 RPL40B 11805837 0007 HT RPL40B RPL1B 22995916 0004 LC RPL40B TY1A-PR1 16554755 0004 HT RPL40B RPL35B 22995916 0004 LC RPL40B TIF1|TIF2 16554755 0004 HT RPL40B STE6 18191224 0007 LC RPL40B KSS1 11805837 0007 HT RPL40B CDC34 16554755 0004 HT RPL40B GFA1 16554755 0004 HT RPL40B CPR1 21179020 0676 HT RPL40B HSC82 15766533,16554755 0004,0004 LC,HT RPL40B VPS1 16554755 0004 HT RPL40B SAN1 11805837 0007 HT RPL40B HYP2 16554755 0004 HT RPL40B GRR1 11805837 0007 HT RPL40B RVS161 16554755 0004 HT RPL40B LSB5 15651983 0096 LC RPL40B VMA5 16554755 0004 HT RPL40B NAB2 19840948 0004 LC RPL40B RAD23 16554755 0004 HT RPL40B UFD4 16554755 0004 HT RPL40B ETR1 16554755 0004 HT RPL40B AKL1 16554755 0004 HT RPL40B UBP14 16554755 0004 HT RPL40B AIM4 21386897 0004 LC RPL40B GND1 16284124 0004 LC RPL40B END3 16554755 0004 HT RPL40B MET30 11805837 0007 HT RPL40B DHH1 16554755 0004 HT RPL40B SWD1 11805837 0007 HT RPL40B RVS167 16554755,11805837 0004,0007 HT RPL40B SSB2 23332755 0401 LC RPL40B CYB5 16554755,16554755 0363,0004 HT RPL40B DSN1 21107429 0004 HT RPL40B RLP7 23945946 0004 LC RPL40B SKP2 11805837 0007 HT RPL40B OTU1 22902402 0004 LC RPL40B BBC1 16554755 0004 HT RPL40B RAD17 18485869 0006 LC RPL40B UFD2 11805837 0007 HT RPL40B UBC7 11805837 0007 HT RPL40B TOM1 16554755 0004 HT RPL40B GCN5 14660704 0676 HT RPL40B MUS81 11805837 0007 HT RPL40B KAP95 16554755 0004 HT RPL40B MMS22 26849847 0004 LC RPL40B URN1 21386897 0004 LC RPL40B PIB1 11805837 0007 HT RPL40B HRT1 11805837 0007 HT RPL40B CUE5 16554755 0004 HT RPL40B TGL5 16554755 0004 HT RPL40B HRT3 11805837 0007 HT RPL40B HIF1 16554755 0004 HT RPL40B GTT2 16554755 0004 HT RPL40B Q99247 11805837 0007 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53104 P0CH08 ATG1 RPL40A 0.183 16319894 P23291 P0CH08 YCK1 RPL40A 0.183 16319894 Q12221 P0CH08 PUF2 RPL40A 0.126 26668354 Q12306 P0CH08 SMT3 RPL40A 0.183 23403034 Q12373 P0CH08 HIF1 RPL40A 0.126 16554755 Q12390 P0CH08 GTT2 RPL40A 0.126 16554755 P25567 P0CH08 SRO9 RPL40A 0.126 22271760 P25644 P0CH08 PAT1 RPL40A 0.126 23222640 P0CH08 P01123 RPL40A YPT1 0.126 16554755 P0CH08 P04806 RPL40A HXK1 0.126 16554755 P0CH08 P06102 RPL40A NOT3 0.126 16554755 P0CX43 P0CH08 RPL1A RPL40A 0.21 22995916 P0CX44 P0CH08 RPL1B RPL40A 0.21 22995916 P0CX57 P0CH08 TY1A-A RPL40A 0.126 16554755 P0CX58 P0CH08 TY1A-PR1 RPL40A 0.126 16554755 P0CX84 P0CH08 RPL35A RPL40A 0.21 22995916 P0CX85 P0CH08 RPL35B RPL40A 0.21 22995916 P10081 P0CH08 TIF2 RPL40A 0.126 16554755 P14742 P0CH08 GFA1 RPL40A 0.126 16554755 P15108 P0CH08 HSC82 RPL40A 0.126 16554755 P21576 P0CH08 VPS1 RPL40A 0.126 16554755 P23301 P0CH08 HYP2 RPL40A 0.126 16554755 P25343 P0CH08 RVS161 RPL40A 0.126 16554755 P31412 P0CH08 VMA5 RPL40A 0.126 16554755 P38071 P0CH08 ETR1 RPL40A 0.126 16554755 P39013 P0CH08 END3 RPL40A 0.126 16554755 P39517 P0CH08 DHH1 RPL40A 0.126 16554755 P39743 P0CH08 RVS167 RPL40A 0.126 16554755 P40312 P0CH08 CYB5 RPL40A 0.126 16554755 P47068 P0CH08 BBC1 RPL40A 0.126 16554755 Q06142 P0CH08 KAP95 RPL40A 0.126 16554755 Q08412 P0CH08 CUE5 RPL40A 0.126 16554755 P0CS90 P0CH08 SSC1 RPL40A 0.126 25792736 P0CH08 P04037 RPL40A COX4 0.126 23864706 P0CH08 P04912 RPL40A HTA2 0.126 16554755 P0CH08 P05317 RPL40A RPP0 0.21 22995916 P0CH08 P06244 RPL40A TPK1 0.183 16319894 P0CH08 P02829 RPL40A HSP82 0.236 15766533,26804907 P25037 P0CH08 UBP1 RPL40A 0.523 2050695,1429680 Q15038 P0CH08 DAZAP2 RPL40A 0.332 27107014 P38080 P0CH08 AKL1 RPL40A 0.286 16554755,16319894 P38237 P0CH08 UBP14 RPL40A 0.126 16554755 P38305 P0CH08 AIM4 RPL40A 0.126 21386897 P32505 P0CH08 NAB2 RPL40A 0.126 19840948 P27466 P0CH08 CMK1 RPL40A 0.183 16319894 P32944 P0CH08 SWE1 RPL40A 0.183 16319894 P40150 P0CH08 SSB2 RPL40A 0.126 23332755 P35127 P0CH08 YUH1 RPL40A 0.309 1429680 P40693 P0CH08 RLP7 RPL40A 0.126 23945946 P40568 P0CH08 DSN1 RPL40A 0.126 21107429 P0CH08 E9PFK9 RPL40A RABGEF1 {ECO:0000313|ENSEMBL:ENSP00000403429} 0.332 27107014 P14682 P0CH08 CDC34 RPL40A 0.126 16554755 P43558 P0CH08 OTU1 RPL40A 0.126 22902402 Q01476 P0CH08 UBP2 RPL40A 0.309 1429680 Q01477 P0CH08 UBP3 RPL40A 0.309 1429680 Q13137 P0CH08 CALCOCO2 RPL40A 0.332 27107014 Q06164 P0CH08 MMS22 RPL40A 0.126 26849847 Q06525 P0CH08 URN1 RPL40A 0.126 21386897 P17157 P0CH08 PHO85 RPL40A 0.183 16319894 Q03280 P0CH08 TOM1 RPL40A 0.126 16554755 P53849 P0CH08 GIS2 RPL40A 0.126 21232131