PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SWE1 CWC24 i2d exp YCK1 CWC24 16319894 biogrid exp ARG3 CWC24 11805837 dip exp CWC24 SNT309 11884590 intact exp ATG1 CWC24 16319894 biogrid,i2d exp SSB1 CWC24 19536198 intact exp PRP9 CWC24 i2d exp SSE2 CWC24 19536198 intact exp SSE1 CWC24 19536198 intact exp SSA2 CWC24 19536198 intact exp RPS31 CWC24 i2d exp SSA1 CWC24 19536198 intact exp PIH1 CWC24 17974558 biogrid exp CWC24 IPK1 10688190, 23023127 biogrid,i2d,mint,intact,dip exp, pred CWC24 CEF1 17974558, 23023127 biogrid exp, pred PRP19 CWC24 11884590, 23023127 biogrid,i2d,intact exp, pred BRR2 CWC24 23029180, 23023127 biogrid exp, pred CWC24 CWC2 11884590, 23023127 biogrid,intact exp, pred PRP2 CWC24 20089683, 23023127 biogrid exp, pred LSM2 CWC24 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q06667 P53769 - 10688190 - X 2 P38768 P53769 two hybrid 17974558 direct interaction X 2 P38768 P53769 two hybrid 17974558 direct interaction X 2 P38768 P53769 affinity chromatography technology 17974558 physical association X 2 Q06667 P53769 two hybrid 10688190 direct interaction X 2 P53104 P53769 enzymatic study 16319894 direct interaction X 2 Q03654 P53769 affinity chromatography technology 17974558 physical association X 2 Q12046 P53769 affinity chromatography technology 11884590 physical association X 2 P23291 P53769 enzymatic study 16319894 direct interaction X 2 P32523 P53769 affinity chromatography technology 11884590 physical association X 2 P32639 P53769 affinity chromatography technology 23029180 physical association X 2 P53769 P20095 affinity chromatography technology 20089683 physical association X 2 Q06667 P53769 two hybrid 10688190 physical association X 2 P05150 P53769 anti tag coimmunoprecipitation 11805837 physical association X 2 P53769 tandem affinity purification 11884590 association C 43 P53769 tandem affinity purification 11884590 association C 31 P10592 P53769 tandem affinity purification 19536198 association X 2 P32589 P53769 tandem affinity purification 19536198 association X 2 P11484 P53769 tandem affinity purification 19536198 association X 2 Q06667 P53769 two hybrid 10688190 physical association X 2 P32590 P53769 tandem affinity purification 19536198 association X 2 P10591 P53769 tandem affinity purification 19536198 association X 2 P53769 tandem affinity purification 11884590 association C 33 Q06667 P53769 two hybrid 10688190 - X 2

PPI - HINT Gene A Gene B PMID Method Quality YCK1 CWC24 16319894 0415 LC PIH1 CWC24 17974558,17974558 0004,0018 LC ATG1 CWC24 16319894 0415 LC CWC24 IPK1 10688190,10688190 0397,0018 HT ARG3 CWC24 11805837 0007 HT SSA1 CWC24 19536198 0676 HT SSA2 CWC24 19536198 0676 HT SSB1 CWC24 19536198 0676 HT PRP2 CWC24 20089683 0004 LC PRP19 CWC24 11884590,11884590 0004,0676 LC SSE1 CWC24 19536198 0676 HT SSE2 CWC24 19536198 0676 HT BRR2 CWC24 23029180 0004 LC PIH1 CWC24 17974558,17974558 0004,0018 LC CWC24 CEF1 17974558 0004 LC CWC24 SNT309 11884590 0676 LC CWC24 CWC2 11884590,11884590 0004,0676 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53769 P53104 CWC24 ATG1 0.183 16319894 P53769 P10592 CWC24 SSA2 0.126 19536198 P53769 P11484 CWC24 SSB1 0.126 19536198 Q12046 P53769 CWC2 CWC24 0.236 11884590 P53769 P38768 CWC24 PIH1 0.623 17974558 P53769 P32523 CWC24 PRP19 0.126 11884590 P53769 P32589 CWC24 SSE1 0.126 19536198 P53769 P32639 CWC24 BRR2 0.21 23029180 Q06091 P53769 SNT309 CWC24 0.126 11884590 P53769 P20095 CWC24 PRP2 0.126 20089683 Q06667 P53769 IPK1 CWC24 0.309 10688190 P53769 P10591 CWC24 SSA1 0.126 19536198 P53769 P05150 CWC24 ARG3 0.126 11805837 P53769 P32590 CWC24 SSE2 0.126 19536198 Q03654 P53769 CEF1 CWC24 0.21 17974558