PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus CAB5 CST9 14690591 intact exp SSA1 CST9 19536198 intact exp NAM7 CST9 18087042 biogrid exp CST9 PUF3 23409723,26493364 biogrid exp SSB1 CST9 19536198 intact exp HEK2 CST9 18805955 biogrid exp FUS3 CST9 16319894 biogrid,i2d exp CDC28 CST9 14574415 biogrid,dip exp HSP82 CST9 19536198 intact exp RAD51 CST9 10943844, 23023127 biogrid,intact,dip exp, pred CST9 SMT3 16847351, 23023127 biogrid exp, pred MRE11 CST9 10943844, 23023127 biogrid,intact,dip exp, pred MSH4 CST9 10943844, 23023127 biogrid,intact exp, pred CST9 MSH5 10943844, 23023127 biogrid,intact,dip exp, pred UBC9 CST9 16847351, 23023127 biogrid exp, pred ZIP2 CST9 10943844, 23023127 biogrid,intact,dip exp, pred ZIP1 CST9 10943844, 23023127 biogrid,intact,dip exp, pred RAD57 CST9 10943844, 23023127 biogrid,intact,dip exp, pred SPO22 CST9 23023127 pred CST9 CSM4 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q06032 P25301 affinity chromatography technology 10943844 physical association X 2 Q06032 P53061 affinity chromatography technology 10943844 physical association X 2 Q06032 P25301 two hybrid 10943844 direct interaction X 2 Q06032 Q12306 enzymatic study 16847351 direct interaction X 2 Q06032 Q12306 two hybrid 16847351 direct interaction X 2 P16892 Q06032 enzymatic study 16319894 direct interaction X 2 Q06032 P32829 affinity chromatography technology 10943844 physical association X 2 Q06032 P40965 affinity chromatography technology 10943844 physical association X 2 Q06032 P31111 affinity chromatography technology 10943844 physical association X 2 Q06032 P25454 two hybrid 10943844 direct interaction X 2 Q06032 P31111 two hybrid 10943844 direct interaction X 2 Q06032 P00546 enzymatic study 14574415 direct interaction X 2 Q06032 P50623 pull down 16847351 direct interaction X 2 Q06032 P50623 two hybrid 16847351 direct interaction X 2 Q12175 Q06032 two hybrid 10943844 direct interaction X 2 Q06032 P53061 coimmunoprecipitation 10943844 physical association X 2 Q06032 P25301 two hybrid 10943844 physical association X 2 Q06032 P25301 coimmunoprecipitation 10943844 physical association X 2 Q06032 P31111 coimmunoprecipitation 10943844 physical association X 2 Q06032 P31111 two hybrid 10943844 physical association X 2 Q06032 P32829 coimmunoprecipitation 10943844 physical association X 2 Q06032 P25454 two hybrid 10943844 physical association X 2 Q06032 P00546 protein kinase assay 14574415 physical association X 2 Q12175 Q06032 two hybrid 10943844 physical association X 2 Q06032 P25301 two hybrid 10943844 physical association X 2 Q06032 P53061 anti tag coimmunoprecipitation 10943844 physical association X 2 Q06032 P53061 fluorescence microscopy 10943844 colocalization X 2 Q06032 P25301 anti tag coimmunoprecipitation 10943844 physical association X 2 Q06032 Q03941 two hybrid array 14690591 physical association X 2 P10591 Q06032 tandem affinity purification 19536198 association X 2 Q06032 P31111 anti tag coimmunoprecipitation 10943844 physical association X 2 Q06032 P31111 two hybrid 10943844 physical association X 2 Q06032 P25454 two hybrid 10943844 physical association X 2 Q06032 P31111 fluorescence microscopy 10943844 colocalization X 2 Q06032 P40965 fluorescence microscopy 10943844 colocalization X 2 Q06032 P32829 fluorescence microscopy 10943844 colocalization X 2 Q06032 P32829 anti tag coimmunoprecipitation 10943844 physical association X 2 Q06032 P40965 anti tag coimmunoprecipitation 10943844 physical association X 2 Q06032 P11484 tandem affinity purification 19536198 association X 2 Q06032 P02829 tandem affinity purification 19536198 association X 2 Q12175 Q06032 two hybrid 10943844 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality CDC28 CST9 14574415,14574415 0424,0415 HT FUS3 CST9 16319894 0415 LC RAD57 CST9 10943844,10943844,10943844,10943844 0004,0007,0018,0019 LC RAD51 CST9 10943844 0018 LC ZIP1 CST9 10943844,10943844,10943844,10943844,10943844 0004,0007,0018,0416,0019 LC MRE11 CST9 10943844,10943844,10943844,10943844 0004,0007,0416,0019 LC MSH4 CST9 10943844,10943844,10943844 0004,0007,0416 LC UBC9 CST9 16847351,16847351 0018,0096 LC ZIP2 CST9 10943844,10943844,10943844,10943844 0004,0007,0416,0019 LC CAB5 CST9 14690591 0397 LC CST9 MSH5 10943844 0018 LC CST9 SMT3 16847351,16847351 0018,0415 LC HSP82 CST9 19536198 0676 HT SSA1 CST9 19536198 0676 HT SSB1 CST9 19536198 0676 HT RAD57 CST9 10943844,10943844,10943844,10943844 0004,0007,0018,0019 LC ZIP1 CST9 10943844,10943844,10943844,10943844,10943844 0004,0007,0018,0416,0019 LC MRE11 CST9 10943844,10943844,10943844,10943844 0004,0007,0416,0019 LC MSH4 CST9 10943844,10943844,10943844 0004,0007,0416 LC UBC9 CST9 16847351,16847351 0018,0096 LC ZIP2 CST9 10943844,10943844,10943844,10943844 0004,0007,0416,0019 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q06032 P16892 CST9 FUS3 0.183 16319894 Q06032 P11484 CST9 SSB1 0.126 19536198 Q06032 P25454 CST9 RAD51 0.332 10943844 Q06032 P53061 CST9 ZIP2 0.21 10943844 Q06032 P40965 CST9 MSH4 0.21 10943844 Q06032 P02829 CST9 HSP82 0.126 19536198 Q06032 P31111 CST9 ZIP1 0.454 10943844 Q12306 Q06032 SMT3 CST9 0.523 16847351 Q06032 P25301 CST9 RAD57 0.454 10943844 Q06032 P50623 CST9 UBC9 0.523 16847351 Q06032 P30771 CST9 NAM7 0.126 18087042 Q06032 P38199 CST9 HEK2 0.126 18805955 Q06032 P32829 CST9 MRE11 0.236 10943844 Q06032 Q03941 CST9 CAB5 0.126 14690591 Q07807 Q06032 PUF3 CST9 0.126 23409723 Q06032 P10591 CST9 SSA1 0.126 19536198 Q06032 P00546 CST9 CDC28 0.21 14574415 Q12175 Q06032 MSH5 CST9 0.309 10943844