PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PRK1 UFO1 20159853 biogrid exp UFO1 UFO1 22815701,14747994 biogrid exp SSB1 UFO1 19536198 intact exp CRM1 UFO1 26673895 biogrid exp RBG1 UFO1 24389104 biogrid exp RPN12 UFO1 22815701 biogrid exp RPO21 UFO1 18949821 biogrid exp SPT5 UFO1 18949821 biogrid exp SHE2 UFO1 11283351 i2d,mint,intact,dip exp DDI1 UFO1 22815701,16478980 biogrid exp GIP2 UFO1 18949821 biogrid exp UBI4 UFO1 25703377 biogrid exp GIS2 UFO1 21232131 biogrid exp RPN11 UFO1 22815701 biogrid exp RPB2 UFO1 18949821 biogrid exp HEK2 UFO1 18805955 biogrid exp FAR1 UFO1 24389104 biogrid exp MTH1 UFO1 24389104 biogrid exp SSA2 UFO1 18949821 biogrid exp JJJ1 UFO1 19536198 intact exp FAS2 UFO1 18949821 biogrid exp GAL1 UFO1 18949821 biogrid exp SSA1 UFO1 18949821 biogrid exp GAL80 UFO1 22479149 biogrid,dip exp HO UFO1 24389104,22815701,14506225 biogrid,i2d exp RPN10 UFO1 22815701 biogrid exp RPL4A UFO1 18949821 biogrid exp UFO1 HRT1 14747994 biogrid exp LSM1 UFO1 10900456, 23023127 biogrid,i2d,mint,intact,dip exp, pred UFO1 CDC53 22815701,14506225,11283612,23535662,21389113,19882662,14747994,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred RPN1 UFO1 22815701,18949821, 23023127 biogrid exp, pred SKP1 UFO1 23535662,21389113,11805837,10688190,14506225,23000173,19882662,16432255,14747994,20581845, 23023127 biogrid,i2d,mint,intact,dip exp, pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q04511 P36068 - 11283351 - X 2 Q04511 Q12018 - 14506225 - X 2 Q04511 - 11805837 - C 8 Q04511 - 11805837 - C 3 Q04511 P52286 - 10688190 - X 2 Q04511 P09932 - 14506225 - X 2 Q04511 P52286 - 14506225 - X 2 P47017 Q04511 - 10900456 - X 2 Q04511 Q04511 affinity chromatography technology 22815701 physical association X 2 Q04511 Q12018 affinity chromatography technology 22815701 physical association X 2 Q04511 P43588 affinity chromatography technology 22815701 physical association X 2 Q04511 P40087 affinity chromatography technology 22815701 physical association X 2 Q04511 P40087 affinity chromatography technology 22815701 physical association X 2 Q04511 P38764 affinity chromatography technology 22815701 physical association X 2 Q04511 P38886 affinity chromatography technology 22815701 physical association X 2 Q04511 P38764 affinity chromatography technology 22815701 physical association X 2 Q04511 Q12018 pull down 14747994 direct interaction X 2 Q04511 Q12018 two hybrid 14506225 direct interaction X 2 Q04511 Q12018 affinity chromatography technology 14506225 physical association X 2 Q04511 Q12018 affinity chromatography technology 23535662 physical association X 2 Q04511 Q12018 affinity chromatography technology 11283612 physical association X 2 Q04511 Q04511 enzymatic study 14747994 direct interaction X 2 Q04511 P40087 two hybrid 16478980 direct interaction X 2 Q04511 P40087 affinity chromatography technology 16478980 physical association X 2 Q04511 P40087 pull down 16478980 direct interaction X 2 Q04511 P19097 affinity chromatography technology 18949821 physical association X 2 Q04511 P10592 affinity chromatography technology 18949821 physical association X 2 Q04511 P40036 affinity chromatography technology 18949821 physical association X 2 Q04511 P10664 affinity chromatography technology 18949821 physical association X 2 Q04511 P19097 pull down 18949821 direct interaction X 2 Q04511 P40036 pull down 18949821 direct interaction X 2 Q04511 P10592 affinity chromatography technology 18949821 physical association X 2 Q04511 P38764 affinity chromatography technology 18949821 physical association X 2 Q04511 Q12018 affinity chromatography technology 21389113 physical association X 2 Q04511 Q12018 affinity chromatography technology 11805837 physical association X 2 Q08273 Q04511 pull down 14747994 direct interaction X 2 P0CG63 Q04511 affinity chromatography technology 23749301 physical association X 2 P0CG63 Q04511 biochemical 23583075 association X 2 P0CG63 Q04511 affinity chromatography technology 23793018 physical association X 2 P0CG63 Q04511 affinity chromatography technology 18949821 physical association X 2 P32496 Q04511 affinity chromatography technology 22815701 physical association X 2 P10591 Q04511 affinity chromatography technology 18949821 physical association X 2 P10591 Q04511 affinity chromatography technology 18949821 physical association X 2 Q04511 P09932 affinity chromatography technology 22815701 physical association X 2 Q04511 P52286 pull down 23000173 direct interaction X 2 Q04511 P52286 pull down 14747994 direct interaction X 2 Q04511 P09932 two hybrid 14506225 direct interaction X 2 Q04511 P09932 affinity chromatography technology 14506225 physical association X 2 Q04511 P52286 two hybrid 14506225 direct interaction X 2 Q04511 P52286 affinity chromatography technology 14506225 physical association X 2 Q04511 P52286 affinity chromatography technology 23535662 physical association X 2 Q04511 P39729 affinity chromatography technology 24389104 physical association X 2 Q04511 P35198 affinity chromatography technology 24389104 physical association X 2 Q04511 P21268 affinity chromatography technology 24389104 physical association X 2 Q04511 P09932 affinity chromatography technology 24389104 physical association X 2 Q04511 P52286 affinity chromatography technology 16432255 physical association X 2 Q04511 P04050 affinity chromatography technology 18949821 physical association X 2 Q04511 P08518 affinity chromatography technology 18949821 physical association X 2 Q04511 P08518 pull down 18949821 direct interaction X 2 Q04511 P40494 enzymatic study 20159853 direct interaction X 2 Q04511 P52286 affinity chromatography technology 20581845 physical association X 2 Q04511 P52286 affinity chromatography technology 21389113 physical association X 2 Q04511 P52286 affinity chromatography technology 11805837 physical association X 2 Q04511 P52286 affinity chromatography technology 11805837 physical association X 2 Q04511 P52286 two hybrid 10688190 direct interaction X 2 P04385 Q04511 affinity chromatography technology 18949821 physical association X 2 P04387 Q04511 affinity chromatography technology 22479149 physical association X 2 P47017 Q04511 two hybrid 10900456 direct interaction X 2 P27692 Q04511 affinity chromatography technology 18949821 physical association X 2 P27692 Q04511 pull down 18949821 direct interaction X 2 Q04511 P36068 two hybrid pooling approach 11283351 physical association X 2 Q04511 Q12018 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04511 Q12018 coimmunoprecipitation 11283612 physical association X 2 Q04511 anti tag coimmunoprecipitation 11805837 - C 9 Q04511 affinity chromatography technology 14747994 - C 4 Q04511 anti tag coimmunoprecipitation 11805837 - C 8 Q04511 anti tag coimmunoprecipitation 11805837 - C 3 Q04511 P52286 two hybrid 10688190 physical association X 2 Q04511 P52286 affinity chromatography technology 14747994 physical association X 2 Q04511 P52286 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04511 P52286 anti tag coimmunoprecipitation 11805837 physical association X 2 P04387 Q04511 pull down 22479149 physical association X 2 P47017 Q04511 two hybrid 10900456 physical association X 2 Q04511 pull down 19882662 association C 35 Q04511 P36068 two hybrid fragment pooling approach 11283351 physical association X 2 Q04511 pull down 19882662 association C 51 Q04511 anti tag coimmunoprecipitation 11805837 association C 8 Q04511 anti tag coimmunoprecipitation 11805837 association C 3 Q04511 anti tag coimmunoprecipitation 11283612 association C 5 Q04511 P52286 two hybrid 10688190 physical association X 2 Q04511 P11484 tandem affinity purification 19536198 association X 2 Q04511 P53863 tandem affinity purification 19536198 association X 2 P47017 Q04511 two hybrid 10900456 physical association X 2 Q04511 mass spectrometry studies of complexes 11805837 - C 9 Q04511 mass spectrometry studies of complexes 11805837 - C 4 Q04511 mass spectrometry studies of complexes 11805837 - C 4 Q04511 P36068 two hybrid 11283351 - X 2 Q04511 P52286 two hybrid 10688190 - X 2 P47017 Q04511 two hybrid 10900456 - X 2

PPI - HINT Gene A Gene B PMID Method Quality HO UFO1 14506225,14506225,14506225 0018,0004,0019 LC SHE2 UFO1 11283351,11283351,11283351 0018,0399,0398 HT DDI1 UFO1 16478980,16478980,16478980 0004,0096,0018 LC PRK1 UFO1 20159853 0415 LC LSM1 UFO1 10900456 0018 HT SKP1 UFO1 14506225,14506225,10688190,14506225,10688190 0004,0019,0397,0018,0018 LC,HT UFO1 UFO1 14747994 0415 LC UFO1 CDC53 14506225,11283612,11283612,11283612,14506225,14506225 0004,0004,0007,0019,0018,0019 LC RPO21 UFO1 18949821 0004 LC GAL1 UFO1 18949821 0004 LC GAL80 UFO1 22479149,22479149 0096,0004 LC RPB2 UFO1 18949821,18949821 0004,0096 LC HO UFO1 14506225,14506225,14506225,24389104,22815701 0018,0004,0019,0004,0004 LC UBI4 UFO1 18949821,25703377 0004,0096 LC SSA1 UFO1 18949821 0004 LC SSA2 UFO1 18949821 0004 LC RPL4A UFO1 18949821 0004 LC SSB1 UFO1 19536198 0676 HT FAS2 UFO1 18949821,18949821 0004,0096 LC FAR1 UFO1 24389104 0004 LC SPT5 UFO1 18949821,18949821 0004,0096 LC CRM1 UFO1 26673895,26673895 0096,0004 LC RPN12 UFO1 22815701 0004 LC MTH1 UFO1 24389104 0004 LC RPN1 UFO1 18949821,22815701 0004,0004 LC RPN10 UFO1 22815701 0004 LC RBG1 UFO1 24389104 0004 LC GIP2 UFO1 18949821,18949821 0004,0096 LC DDI1 UFO1 16478980,16478980,16478980,22815701 0004,0096,0018,0004 LC RPN11 UFO1 22815701 0004 LC SKP1 UFO1 11805837,23000173,14506225,14747994,19882662,20581845,14506225,14747994,21389113,11805837,16432255,14506225,23535662 0004,0096,0004,0004,0096,0004,0019,0096,0004,0007,0004,0018,0004 HT,LC JJJ1 UFO1 19536198 0676 HT UFO1 UFO1 22815701 0004 LC UFO1 HRT1 14747994 0096 LC UFO1 CDC53 11805837,14506225,11283612,11283612,19882662,11283612,11805837,14747994,21389113,14506225,22815701,14506225,23535662 0004,0004,0004,0007,0096,0019,0007,0096,0004,0018,0004,0019,0004 HT,LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q04511 P32496 UFO1 RPN12 0.21 22815701 Q04511 P04385 UFO1 GAL1 0.21 18949821 Q04511 P21268 UFO1 FAR1 0.21 24389104 Q04511 P04050 UFO1 RPO21 0.21 18949821 Q04511 P0CG63 UFO1 UBI4 0.309 25703377 Q04511 P10591 UFO1 SSA1 0.21 18949821 Q04511 P11484 UFO1 SSB1 0.126 19536198 Q04511 P10592 UFO1 SSA2 0.21 18949821 Q04511 P10664 UFO1 RPL4A 0.21 18949821 Q04511 P43588 UFO1 RPN11 0.21 22815701 Q04511 P35198 UFO1 MTH1 0.21 24389104 Q04511 P39729 UFO1 RBG1 0.21 24389104 Q04511 P47017 UFO1 LSM1 0.354 10900456 Q04511 P53863 UFO1 JJJ1 0.126 19536198 Q04511 P04387 UFO1 GAL80 0.21 22479149 Q04511 P08518 UFO1 RPB2 0.454 18949821 Q04511 P09932 UFO1 HO 0.376 24389104,22815701 Q04511 P19097 UFO1 FAS2 0.454 18949821 Q04511 P27692 UFO1 SPT5 0.454 18949821 Q04511 P40036 UFO1 GIP2 0.454 18949821 Q04511 Q04511 UFO1 UFO1 0.49 22815701,14747994 Q04511 P40087 UFO1 DDI1 0.765 22815701,16478980 Q04511 P52286 UFO1 SKP1 0.867 10688190,20581845,11805837,19882662,14747994,23535662,23000173,21389113 Q12018 Q04511 CDC53 UFO1 0.848 22815701,11283612,21389113,11805837,19882662,14747994,23535662 Q04511 P36068 UFO1 SHE2 0.236 11283351 Q04511 P30822 UFO1 CRM1 0.126 26673895 Q04511 P38199 UFO1 HEK2 0.126 18805955 Q04511 P38764 UFO1 RPN1 0.507 22815701,18949821 Q04511 P38886 UFO1 RPN10 0.21 22815701 Q04511 P40494 UFO1 PRK1 0.309 20159853 Q04511 P53849 UFO1 GIS2 0.126 21232131