PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PEX18 PEX12 24034674 biogrid exp CHC1 PEX12 11805837 dip exp ERG6 PEX12 21748599 biogrid exp FAS1 PEX12 11805837 dip exp UBC4 PEX12 22471590 biogrid exp NAB2 PEX12 19840948 biogrid exp PEX17 PEX12 12667447, 23023127 biogrid,intact exp, pred PEX12 PEX10 11370741,22471590,12667447,12876220,20655618, 23023127 biogrid,intact,dip exp, pred PEX12 PEX15 12876220, 23023127 biogrid,dip exp, pred PEX14 PEX12 11370741,12667447,22375831, 23023127 biogrid,intact exp, pred PEX5 PEX12 11370741,16849337,12667447,15456864,25162638, 23023127 biogrid,intact exp, pred PEX4 PEX12 22471590,24034674,25162638, 23023127 biogrid exp, pred FRE1 PEX12 16093310, 23023127 biogrid,dip exp, pred PEX2 PEX12 19687296,22471590,12667447,22500805, 23023127 biogrid,intact exp, pred PEX12 PEX19 12876220,19451657, 23023127 biogrid,dip exp, pred PEX13 PEX12 11370741,12667447,12876220,20655618,22500805, 23023127 biogrid,mint,intact,dip exp, pred PEX8 PEX12 12667447,20655618, 23023127 biogrid,intact exp, pred PEX12 PEX11 22615397,18467557, 23023127 biogrid,i2d,mint,intact exp, pred BUD14 PEX12 19841731, 23023127 biogrid,mint,intact exp, pred PEX22 PEX12 12876220, 23023127 dip exp, pred PEX12 PEX12 11370741, 23023127 biogrid exp, pred PEX7 PEX12 23023127 pred PEX3 PEX12 23023127 pred PEX6 PEX12 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q04370 P53112 affinity chromatography technology 12667447 physical association X 2 Q04370 P53248 affinity chromatography technology 12667447 physical association X 2 Q04370 P80667 affinity chromatography technology 12667447 physical association X 2 Q04370 P53112 affinity chromatography technology 12667447 physical association X 2 Q04370 P40155 affinity chromatography technology 12667447 physical association X 2 Q04370 P35056 affinity chromatography technology 12667447 physical association X 2 Q04370 P35056 affinity chromatography technology 15456864 physical association X 2 Q04370 Q07418 unspecified method 19451657 direct interaction X 2 Q04370 P80667 biochemical 11370741 association X 2 Q04370 P35056 biochemical 11370741 association X 2 Q04370 P53112 biochemical 11370741 association X 2 Q04370 P35056 enzymatic study 25162638 direct interaction X 2 Q04370 P35056 affinity chromatography technology 16849337 physical association X 2 Q04370 Q12462 protein complementation assay 18467557 direct interaction X 2 Q04370 P27637 two hybrid 19841731 direct interaction X 2 Q04370 Q07418 protein complementation assay 12876220 direct interaction X 2 Q04370 Q08215 protein complementation assay 12876220 direct interaction X 2 Q04370 P80667 protein complementation assay 12876220 direct interaction X 2 Q04370 P32791 protein complementation assay 16093310 direct interaction X 2 Q04370 P53248 affinity chromatography technology 20655618 physical association X 2 Q04370 P80667 affinity chromatography technology 20655618 physical association X 2 Q04370 P80667 affinity chromatography technology 20655618 physical association X 2 Q04370 Q12462 protein complementation assay 22615397 direct interaction X 2 Q04370 P53112 affinity chromatography technology 22375831 physical association X 2 P25087 Q04370 protein complementation assay 21748599 direct interaction X 2 Q04370 P32800 imaging technique 22500805 colocalization X 2 Q04370 P32800 affinity chromatography technology 12667447 physical association X 2 Q04370 Q05568 affinity chromatography technology 12667447 physical association X 2 Q04370 Q05568 affinity chromatography technology 12667447 physical association X 2 Q04370 P32800 affinity chromatography technology 12667447 physical association X 2 Q04370 Q04370 two hybrid 11370741 direct interaction X 2 Q04370 Q05568 biochemical 11370741 association X 2 Q04370 P15731 pull down 22471590 direct interaction X 2 Q04370 P32800 pull down 22471590 direct interaction X 2 Q04370 P32800 pull down 22471590 direct interaction X 2 Q04370 Q05568 pull down 22471590 direct interaction X 2 Q04370 Q05568 pull down 22471590 direct interaction X 2 Q04370 P38855 enzymatic study 24034674 direct interaction X 2 Q04370 Q05568 protein complementation assay 12876220 direct interaction X 2 Q04370 P32800 affinity chromatography technology 19687296 physical association X 2 Q04370 Q05568 affinity chromatography technology 20655618 physical association X 2 P29340 Q04370 pull down 25162638 direct interaction X 2 P29340 Q04370 pull down 22471590 direct interaction X 2 P29340 Q04370 pull down 24034674 direct interaction X 2 Q04370 anti tag coimmunoprecipitation 11805837 - C 3 Q04370 P32791 ubiquitin reconstruction 16093310 physical association X 2 Q04370 P07149 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04370 P22137 anti tag coimmunoprecipitation 11805837 physical association X 2 Q04370 P80667 ubiquitin reconstruction 12876220 physical association X 2 Q04370 Q08215 ubiquitin reconstruction 12876220 physical association X 2 Q04370 Q07418 ubiquitin reconstruction 12876220 physical association X 2 Q04370 Q05568 coimmunoprecipitation 12876220 physical association X 2 Q04370 Q05568 ubiquitin reconstruction 12876220 physical association X 2 P39718 Q04370 coimmunoprecipitation 12876220 physical association X 2 Q04370 pull down 12667447 association C 5 Q04370 pull down 12667447 association C 5 Q04370 pull down 12667447 association C 8 Q04370 pull down 12667447 association C 6 Q04370 pull down 12667447 association C 6 Q04370 pull down 12667447 association C 6 Q04370 pull down 12667447 association C 6 Q04370 pull down 12667447 association C 6 Q04370 pull down 12667447 association C 6 Q04370 pull down 12667447 association C 8 Q04370 pull down 12667447 association C 8 Q04370 pull down 12667447 association C 8 Q04370 pull down 12667447 association C 8 Q04370 pull down 12667447 association C 8 Q04370 pull down 12667447 association C 4 Q04370 pull down 12667447 association C 3 Q04370 P80667 ubiquitin reconstruction 12876220 physical association X 2 Q04370 Q12462 dihydrofolate reductase reconstruction 18467557 physical association X 2 Q04370 P27637 two hybrid pooling approach 19841731 physical association X 2 Q04370 P80667 fluorescence microscopy 22500805 colocalization X 2 Q04370 pull down 12667447 association C 6 Q04370 pull down 12667447 association C 5 Q04370 pull down 12667447 association C 5 Q04370 blue native page 12667447 physical association C 4 Q04370 pull down 12667447 association C 3 Q04370 pull down 12667447 association C 3 Q04370 pull down 12667447 association C 7 Q04370 pull down 12667447 association C 6 Q04370 pull down 12667447 association C 7 Q04370 pull down 12667447 association C 7 Q04370 Q05568 blue native page 12667447 physical association X 2 Q04370 Q05568 blue native page 12667447 physical association X 2 Q04370 Q05568 pull down 12667447 physical association X 2 Q04370 Q05568 pull down 12667447 association X 2 Q04370 P32800 fluorescence microscopy 22500805 colocalization X 2

PPI - HINT Gene A Gene B PMID Method Quality ERG6 PEX12 21748599 0090 HT BUD14 PEX12 19841731,19841731 0398,0018 HT FRE1 PEX12 16093310,16093310 0090,0112 HT PEX2 PEX12 22500805,22500805 0428,0416 LC PEX5 PEX12 11370741,25162638 0401,0415 LC PEX18 PEX12 24034674 0415 LC PEX22 PEX12 12876220 0019 LC PEX14 PEX12 11370741 0401 LC PEX13 PEX12 12876220,11370741,12876220,22500805 0090,0401,0112,0416 LC PEX12 PEX12 11370741 0018 LC PEX12 PEX10 12876220,12876220,12667447,11370741,12876220,12667447,12667447 0090,0019,0004,0401,0112,0096,0276 LC PEX12 PEX19 12876220,12876220 0112,0090 LC PEX12 PEX15 12876220,12876220 0112,0090 LC PEX12 PEX11 18467557,18467557,22615397 0111,0090,0090 HT,LC FAS1 PEX12 11805837 0007 HT UBC4 PEX12 22471590 0096 LC CHC1 PEX12 11805837 0007 HT PEX4 PEX12 25162638,24034674,22471590 0096,0096,0096 LC NAB2 PEX12 19840948 0004 LC PEX2 PEX12 22500805,19687296,12667447,22471590,12667447,22500805 0428,0004,0004,0096,0096,0416 LC PEX5 PEX12 12667447,15456864,11370741,12667447,16849337 0004,0004,0401,0096,0004 LC PEX17 PEX12 12667447,12667447 0096,0004 LC PEX14 PEX12 12667447,12667447,11370741,22375831 0096,0004,0401,0004 LC PEX8 PEX12 12667447,20655618,12667447 0096,0004,0004 LC PEX13 PEX12 12667447,11370741,20655618,12667447 0004,0401,0004,0096 LC PEX12 PEX10 12667447,22471590,11370741,20655618,12667447,12667447 0004,0096,0401,0004,0096,0276 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q04370 P25087 PEX12 ERG6 0.183 21748599 Q12462 Q04370 PEX11 PEX12 0.126 18467557 Q05568 Q04370 PEX10 PEX12 0.899 12667447,12876220,20655618,22471590 Q04370 P29340 PEX12 PEX4 0.671 25162638,24034674,22471590 Q04370 P32505 PEX12 NAB2 0.126 19840948 Q04370 P32791 PEX12 FRE1 0.183 16093310 Q04370 P35056 PEX12 PEX5 0.569 12667447,25162638,15456864 Q07418 Q04370 PEX19 PEX12 0.436 19451657,12876220 Q08215 Q04370 PEX15 PEX12 0.21 12876220 Q04370 P80667 PEX12 PEX13 0.659 12667447,12876220,20655618,22500805 Q04370 P22137 PEX12 CHC1 0.126 11805837 Q04370 P53248 PEX12 PEX8 0.376 12667447,20655618 Q04370 P15731 PEX12 UBC4 0.309 22471590 Q04370 P07149 PEX12 FAS1 0.126 11805837 Q04370 P53112 PEX12 PEX14 0.507 12667447,22375831 Q04370 P40155 PEX12 PEX17 0.21 12667447 Q04370 P27637 PEX12 BUD14 0.376 19841731 Q04370 P39718 PEX12 PEX22 0.033 12876220 Q04370 P32800 PEX12 PEX2 0.772 12667447,19687296,22471590,22500805 Q04370 P38855 PEX12 PEX18 0.309 24034674