PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SSA1 RRB1 26217697,23217712 biogrid,intact exp HHT1, HHT2 RRB1 22199229 biogrid exp FPR3 RRB1 21179020 intact exp GCN5 RRB1 14660704 intact exp AMD1 RRB1 16554755 intact exp FMP32 RRB1 11728313 biogrid exp RRB1 VAM6 25026036 biogrid exp RRB1 POC4 16554755 biogrid,mint,intact exp SBP1 RRB1 23222640 biogrid exp AIM4 RRB1 10684247 intact exp SSA3 RRB1 19536198 intact exp SSB2 RRB1 23332755,19536198 biogrid,intact exp RTT102 RRB1 14660704 biogrid,intact exp MAD2 RRB1 14660704 biogrid,intact exp RPS2 RRB1 11728313 biogrid exp SSB1 RRB1 19536198 intact exp Inactive deaminase YJL070C RRB1 16554755 biogrid,mint,intact exp RPS22A RRB1 11728313 biogrid exp RRB1 BUD30 i2d exp GIS2 RRB1 21232131 biogrid exp PHO4 RRB1 14660704 biogrid,intact exp RRB1 MDN1 16554755, 23023127 biogrid,mint,intact exp, pred RRB1 RRP6 14759368, 23023127 biogrid,mint,intact exp, pred NOP7 RRB1 15467761, 23023127 biogrid,i2d exp, pred RPL3 RRB1 14759368,11158312, 23023127 biogrid,mint,intact,dip exp, pred NUP116 RRB1 10684247, 23023127 biogrid exp, pred RPS3 RRB1 11728313, 23023127 biogrid exp, pred RRB1 TYW1 16554755, 23023127 biogrid,mint,intact exp, pred RRB1 RRB1 14759368, 23023127 biogrid,mint,intact exp, pred RLP7 RRB1 11728313,23945946, 23023127 biogrid exp, pred SSN3 RRB1 20489023, 23023127 biogrid,mint,intact exp, pred RRB1 HSH49 11728313, 23023127 biogrid exp, pred DIM1 RRB1 ortho RPC19 RRB1 ortho ENP2 RRB1 ortho NOC2 RRB1 ortho RRB1 UTP21 ortho RRB1 MRD1 ortho CDC48 RRB1 ortho CRM1 RRB1 ortho TOP1 RRB1 ortho RRB1 MEX67 ortho RRB1 DBP9 ortho ATG8 RRB1 ortho NOG1 RRB1 23023127 ortho, pred HAS1 RRB1 23023127 ortho, pred ROK1 RRB1 23023127 pred RRB1 DBP10 23023127 pred RRB1 DIP2 23023127 pred RRP3 RRB1 23023127 pred RRB1 TFC8 23023127 pred SOF1 RRB1 23023127 pred RRB1 RRP9 23023127 pred HCA4 RRB1 23023127 pred MOT1 RRB1 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q04225 P14126 - 14759368 - X 2 P40693 Q04225 affinity chromatography technology 23945946 physical association X 2 P40693 Q04225 affinity chromatography technology 11728313 physical association X 2 Q04225 P25443 affinity chromatography technology 11728313 physical association X 2 Q04225 Q02630 biochemical 10684247 association X 2 Q04225 P40361 affinity chromatography technology 16554755 physical association X 2 P53330 Q04225 affinity chromatography technology 14660704 physical association X 2 P40958 Q04225 affinity chromatography technology 14660704 physical association X 2 P43557 Q04225 affinity chromatography technology 11728313 physical association X 2 Q12149 Q04225 affinity chromatography technology 14759368 physical association X 2 Q12019 Q04225 affinity chromatography technology 16554755 physical association X 2 Q04225 P14126 affinity chromatography technology 11158312 physical association X 2 Q04225 P0C0W1 affinity chromatography technology 11728313 physical association X 2 Q04225 P05750 affinity chromatography technology 11728313 physical association X 2 Q04225 P53261 affinity chromatography technology 15467761 physical association X 2 Q04225 P39073 affinity chromatography technology 20489023 physical association X 2 Q04225 P14126 affinity chromatography technology 14759368 physical association X 2 Q04225 Q04225 affinity chromatography technology 14759368 physical association X 2 Q04225 P61830 affinity chromatography technology 22199229 physical association X 2 Q04225 P61830 affinity chromatography technology 22199229 physical association X 2 P07270 Q04225 affinity chromatography technology 14660704 physical association X 2 P40150 Q04225 biochemical 23332755 association X 2 Q99181 Q04225 affinity chromatography technology 11728313 physical association X 2 Q08960 Q04225 affinity chromatography technology 16554755 physical association X 2 Q12245 Q04225 affinity chromatography technology 16554755 physical association X 2 Q04225 P14126 coimmunoprecipitation 11158312 physical association X 2 Q04225 pull down 23217712 association C 317 Q04225 tandem affinity purification 14660704 association C 42 Q04225 tandem affinity purification 14660704 association C 111 Q04225 inferred by author 16554755 association C 3 Q04225 chromatography technology 10684247 physical association C 57 Q04225 tandem affinity purification 21179020 association C 24 P11484 Q04225 tandem affinity purification 19536198 association X 2 Q04225 P40361 tandem affinity purification 16554755 physical association X 2 Q04225 P40361 tandem affinity purification 16554755 physical association X 2 Q12149 Q04225 anti tag coimmunoprecipitation 14759368 physical association X 2 Q12019 Q04225 tandem affinity purification 16554755 physical association X 2 Q12019 Q04225 tandem affinity purification 16554755 physical association X 2 Q04225 anti tag coimmunoprecipitation 20489023 association C 14 Q04225 tandem affinity purification 14660704 association C 11 Q04225 tandem affinity purification 14660704 association C 103 Q04225 P14126 anti tag coimmunoprecipitation 14759368 physical association X 2 Q04225 Q04225 anti tag coimmunoprecipitation 14759368 physical association X 2 Q04225 P09435 tandem affinity purification 19536198 association X 2 P40150 Q04225 tandem affinity purification 19536198 association X 2 Q08960 Q04225 tandem affinity purification 16554755 physical association X 2 Q08960 Q04225 tandem affinity purification 16554755 physical association X 2 Q12245 Q04225 tandem affinity purification 16554755 physical association X 2 Q12245 Q04225 tandem affinity purification 16554755 physical association X 2

PPI - HINT Gene A Gene B PMID Method Quality RPL3 RRB1 11158312,11158312 0019,0004 LC AIM4 RRB1 10684247 0091 LC SSB2 RRB1 23332755 0401 LC NUP116 RRB1 10684247 0401 LC RPS3 RRB1 11728313 0004 LC PHO4 RRB1 14660704,14660704 0676,0004 HT SSA3 RRB1 19536198 0676 HT RPS22A RRB1 11728313 0004 LC SSA1 RRB1 23217712,26217697 0096,0004 LC SSB1 RRB1 19536198 0676 HT RPL3 RRB1 14759368,14759368,11158312,11158312 0004,0007,0019,0004 HT,LC AMD1 RRB1 16554755 0363 HT RPS2 RRB1 11728313 0004 LC FPR3 RRB1 21179020 0676 HT SSN3 RRB1 20489023,20489023 0007,0004 HT SSB2 RRB1 19536198,23332755 0676,0401 HT,LC P40361 RRB1 16554755,16554755 0676,0004 HT RLP7 RRB1 23945946,11728313 0004,0004 LC MAD2 RRB1 14660704,14660704 0676,0004 HT FMP32 RRB1 11728313 0004 LC NOP7 RRB1 15467761 0004 LC RTT102 RRB1 14660704,14660704 0676,0004 HT HHT1|HHT2 RRB1 22199229 0004 HT NUP116 RRB1 10684247 0401 LC GCN5 RRB1 14660704 0676 HT RRB1 RRB1 14759368,14759368 0004,0007 HT RRB1 TYW1 16554755,16554755 0676,0004 HT RRB1 MDN1 16554755,16554755 0676,0004 HT RRB1 RRP6 14759368,14759368 0004,0007 HT RRB1 POC4 16554755,16554755 0676,0004 HT RRB1 HSH49 11728313 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q12019 Q04225 MDN1 RRB1 0.332 16554755 Q12149 Q04225 RRP6 RRB1 0.126 14759368 Q12221 Q04225 PUF2 RRB1 0.126 26668354 Q04225 P10080 RRB1 SBP1 0.126 23222640 Q04225 P02829 RRB1 HSP82 0.126 26804907 Q04225 P09435 RRB1 SSA3 0.126 19536198 Q04225 P10591 RRB1 SSA1 0.236 23217712,26217697 Q04225 P07270 RRB1 PHO4 0.236 14660704 Q12245 Q04225 POC4 RRB1 0.236 16554755 Q04225 P53330 RRB1 RTT102 0.236 14660704 Q04225 P40958 RRB1 MAD2 0.236 14660704 Q04225 P38305 RRB1 AIM4 0.126 10684247 Q04225 P38911 RRB1 FPR3 0.126 21179020 Q04225 P39073 RRB1 SSN3 0.286 20489023 Q04225 P40150 RRB1 SSB2 0.236 23332755,19536198 Q04225 P40361 RRB1 P40361 0.236 16554755 Q04225 P40693 RRB1 RLP7 0.309 23945946,11728313 Q04225 P15274 RRB1 AMD1 0.126 16554755 Q04225 Q03330 RRB1 GCN5 0.126 14660704 Q07468 Q04225 VAM6 RRB1 0.126 25026036 Q04225 P53849 RRB1 GIS2 0.126 21232131 Q04225 P25443 RRB1 RPS2 0.21 11728313 Q04225 P14126 RRB1 RPL3 0.309 14759368,11158312 Q04225 P11484 RRB1 SSB1 0.126 19536198 Q04225 P0C0W1 RRB1 RPS22A 0.21 11728313 Q04225 P05750 RRB1 RPS3 0.21 11728313 Q04225 Q04225 RRB1 RRB1 0.155 14759368 Q04225 P43557 RRB1 FMP32 0.21 11728313 Q99181 Q04225 HSH49 RRB1 0.21 11728313 Q08960 Q04225 TYW1 RRB1 0.332 16554755