PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RPS31 DSK2 i2d exp SSB1 DSK2 19536198 intact exp DSK2 PDH1 16554755 biogrid,i2d,mint,intact exp RPN2 DSK2 12200120 dip exp RPL40A DSK2 11805121 i2d,dip exp IRC22 DSK2 24709957 biogrid exp UBI4 DSK2 24709957,11805328,17198374,11805121,20059542,23649778,17082762,19620964,16140271,15242647,15837191,12051757 biogrid,i2d,mint,intact exp DSK2 ELA1 23993092 biogrid exp SRO9 DSK2 22271760 biogrid exp DSK2 HOT1 i2d exp HEK2 DSK2 18805955 biogrid exp DSK2 ELC1 23993092 biogrid exp SIC1 DSK2 i2d exp RPL40B DSK2 i2d exp DSK2 SRC1 10688190 mint,intact exp SSA1 DSK2 19536198 intact exp DSK2 VAM6 25026036 biogrid exp GND1 DSK2 16284124 intact exp LYP1 DSK2 16554755 biogrid,i2d,mint,intact exp DSK2 RPT6 16712842 mint,intact exp Uncharacterized protein YEL025C DSK2 16554755 biogrid,i2d,mint,intact exp ARC40 DSK2 i2d exp HXK2 DSK2 i2d exp RPT1 DSK2 18995839,17082762,16712842,11805328,20061387, 23023127 biogrid,mint,intact exp, pred PTH2 DSK2 17082762,18719252, 23023127 biogrid,mint,intact exp, pred DSK2 RUB1 23105008, 23023127 biogrid exp, pred DSK2 UBC7 14690591, 23023127 intact exp, pred DSK2 UFD2 15652483,20427284,16427015,16338354,18719252,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred RPN13 DSK2 20059542, 23023127 biogrid,mint,intact exp, pred PRE1 DSK2 16712842,20061387, 23023127 biogrid,mint,intact exp, pred RPN11 DSK2 20170199,21627799,16284124,20061387,18757749, 23023127 biogrid exp, pred RPN12 DSK2 20061387, 23023127 biogrid exp, pred DSK2 CUE5 16554755, 23023127 biogrid,i2d,mint,intact exp, pred PHO85 DSK2 16319894, 23023127 biogrid,i2d exp, pred STE7 DSK2 20489023, 23023127 biogrid,mint,intact exp, pred RAD23 DSK2 17082762,11805121, 23023127 biogrid,intact,dip exp, pred MOB1 DSK2 20489023, 23023127 biogrid,mint,intact exp, pred RPN1 DSK2 22318722,12198498,21627799, 23023127 biogrid,dip exp, pred DSK2 RPN9 12200120,12051757, 23023127 biogrid,dip exp, pred DSK2 DSK2 16140271, 23023127 biogrid exp, pred RPN10 DSK2 18995839,20059542,17082762,20064467, 23023127 biogrid,mint,intact exp, pred DSK2 SLT2 20489023, 23023127 biogrid,mint,intact exp, pred IKS1 DSK2 20489023, 23023127 biogrid,mint,intact exp, pred HOG1 DSK2 20489023, 23023127 biogrid,mint,intact exp, pred DSK2 HCH1 11283351, 23023127 i2d,mint,intact,dip exp, pred RPT5 DSK2 12200120,21627799, 23023127 biogrid,dip exp, pred WWM1 DSK2 18719252, 23023127 biogrid,intact exp, pred RPO21 DSK2 23056298,21211725, 23023127 biogrid exp, pred RPT3 DSK2 17082762, 23023127 biogrid,mint,intact exp, pred NHP6B DSK2 23023127 pred DSK2 CUE3 23023127 pred DSK2 MYO5 23023127 pred EDE1 DSK2 23023127 pred DSK2 UBX5 23023127 pred MYO3 DSK2 23023127 pred UBA1 DSK2 23023127 pred DSK2 LAS17 23023127 pred SCP160 DSK2 23023127 pred UBC5 DSK2 23023127 pred YUH1 DSK2 23023127 pred DDI1 DSK2 23023127 pred CDC34 DSK2 23023127 pred UBC1 DSK2 23023127 pred UBX7 DSK2 23023127 pred UBC4 DSK2 23023127 pred CDC48 DSK2 23023127 pred DSK2 SMT3 23023127 pred DSK2 SKP1 23023127 pred SHP1 DSK2 23023127 pred EGD2 DSK2 23023127 pred DSK2 RUP1 23023127 pred UBP14 DSK2 23023127 pred DSK2 UBC9 23023127 pred DSK2 UBI4 23023127 pred OTU1 DSK2 23023127 pred DSK2 UBX3 23023127 pred CUE1 DSK2 23023127 pred RAD6 DSK2 23023127 pred TAF5 DSK2 23023127 pred DSK2 VPS9 23023127 pred DSK2 CUE4 23023127 pred BBC1 DSK2 23023127 pred DOA4 DSK2 23023127 pred DSK2 HUB1 23023127 pred DSK2 MDY2 23023127 pred DSK2 UBX4 23023127 pred TUB3 DSK2 23023127 pred DSK2 VPS20 23023127 pred GSP1 DSK2 23023127 pred PAN1 DSK2 23023127 pred YDJ1 DSK2 23023127 pred CUE2 DSK2 23023127 pred UBP6 DSK2 23023127 pred UBC6 DSK2 23023127 pred CDC24 DSK2 23023127 pred UBX6 DSK2 23023127 pred RVS167 DSK2 23023127 pred UBC8 DSK2 23023127 pred TUP1 DSK2 23023127 pred DSK2 GGA1 23023127 pred CMD1 DSK2 23023127 pred GGA2 DSK2 23023127 pred YSC84 DSK2 23023127 pred SLA1 DSK2 23023127 pred BZZ1 DSK2 23023127 pred DSK2 SWA2 23023127 pred CDC31 DSK2 23023127 pred BIK1 DSK2 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P48510 P38634 - 15242647 - X 2 P48510 - 11805837 - C 9 P48510 P53834 - 11283351 - X 2 P48510 - 15652483 - X 2 P62918 P48510 affinity chromatography technology 23649778 physical association X 2 P51881 P48510 affinity chromatography technology 23649778 physical association X 2 P0CG63 P48510 two hybrid 11805121 direct interaction X 2 P0CG63 P48510 affinity chromatography technology 23749301 physical association X 2 P0CG63 P48510 x-ray crystallography 15837191 association X 2 P0CG63 P48510 pull down 15837191 direct interaction X 2 P0CG63 P48510 two hybrid 11805328 direct interaction X 2 P0CG63 P48510 affinity chromatography technology 24709957 physical association X 2 P0CG63 P48510 affinity chromatography technology 17644757 physical association X 2 P0CG63 P48510 affinity chromatography technology 23793018 physical association X 2 P0CG63 P48510 pull down 11805328 direct interaction X 2 P0CG63 P48510 pull down 12051757 direct interaction X 2 P0CG63 P48510 biochemical 16140271 colocalization X 2 P0CG63 P48510 pull down 16140271 direct interaction X 2 P0CG63 P48510 pull down 17082762 direct interaction X 2 P0CG63 P48510 affinity chromatography technology 17082762 physical association X 2 P0CG63 P48510 pull down 15242647 direct interaction X 2 P0CG63 P48510 affinity chromatography technology 23105008 physical association X 2 P0CG63 P48510 pull down 17198374 direct interaction X 2 P0CG63 P48510 affinity chromatography technology 21763274 physical association X 2 P0CG63 P48510 affinity chromatography technology 21763274 physical association X 2 P0CG63 P48510 pull down 19620964 direct interaction X 2 P0CG63 P48510 affinity chromatography technology 22106047 physical association X 2 P61222 P48510 affinity chromatography technology 23649778 physical association X 2 P61514 P48510 affinity chromatography technology 23649778 physical association X 2 Q00772 P48510 affinity chromatography technology 20489023 physical association X 2 P48510 P55034 affinity chromatography technology 20059542 physical association X 2 P48510 Q16186 affinity chromatography technology 20059542 physical association X 2 P48510 P04050 affinity chromatography technology 23056298 physical association X 2 P48510 Q04062 affinity chromatography technology 12200120 physical association X 2 P48510 P32628 two hybrid 11805121 direct interaction X 2 P48510 P0CG50 affinity chromatography technology 23649778 physical association X 2 P48510 P0CG50 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q3U7T8 affinity chromatography technology 23649778 physical association X 2 P48510 E9Q5H9 affinity chromatography technology 23649778 physical association X 2 P48510 Q8BP47 affinity chromatography technology 23649778 physical association X 2 P48510 Q8BJY7 affinity chromatography technology 23649778 physical association X 2 P48510 Q03265 affinity chromatography technology 23649778 physical association X 2 P48510 Q925I1 affinity chromatography technology 23649778 physical association X 2 P48510 P16381 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 A2AHJ7 affinity chromatography technology 23649778 physical association X 2 P48510 Q3UHZ3 affinity chromatography technology 23649778 physical association X 2 P48510 P62631 affinity chromatography technology 23649778 physical association X 2 P48510 P57776 affinity chromatography technology 23649778 physical association X 2 P48510 Q8CJG0 affinity chromatography technology 23649778 physical association X 2 P48510 Q99L45 affinity chromatography technology 23649778 physical association X 2 P48510 Q9Z0N2 affinity chromatography technology 23649778 physical association X 2 P48510 Q99ME9 affinity chromatography technology 23649778 physical association X 2 P48510 P68040 affinity chromatography technology 23649778 physical association X 2 P48510 P63017 affinity chromatography technology 23649778 physical association X 2 P48510 P11499 affinity chromatography technology 23649778 physical association X 2 P48510 Q9Z2X1 affinity chromatography technology 23649778 physical association X 2 P48510 Q570Z0 affinity chromatography technology 23649778 physical association X 2 P48510 Q8VEK3 affinity chromatography technology 23649778 physical association X 2 P48510 Q8VDM6-2 affinity chromatography technology 23649778 physical association X 2 P48510 Q64523 affinity chromatography technology 23649778 physical association X 2 P48510 O70503 affinity chromatography technology 23649778 physical association X 2 P48510 Q8BU30 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q9CPR5 affinity chromatography technology 23649778 physical association X 2 P48510 Q9D1B9 affinity chromatography technology 23649778 physical association X 2 P48510 Q9CQN7 affinity chromatography technology 23649778 physical association X 2 P48510 Q8K2Y7 affinity chromatography technology 23649778 physical association X 2 P48510 P58059 affinity chromatography technology 23649778 physical association X 2 P48510 Q80ZS3 affinity chromatography technology 23649778 physical association X 2 P48510 Q80X85 affinity chromatography technology 23649778 physical association X 2 P48510 P09405 affinity chromatography technology 23649778 physical association X 2 P48510 Q8C0C7 affinity chromatography technology 23649778 physical association X 2 P48510 Q921K2 affinity chromatography technology 23649778 physical association X 2 P48510 Q62029 affinity chromatography technology 23649778 physical association X 2 P48510 Q9D4E6 affinity chromatography technology 23649778 physical association X 2 P48510 P62334 affinity chromatography technology 23649778 physical association X 2 P48510 P14685 affinity chromatography technology 23649778 physical association X 2 P48510 Q8BVQ9 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 P47955 affinity chromatography technology 23649778 physical association X 2 P48510 Q6ZWV3 affinity chromatography technology 23649778 physical association X 2 P48510 Q9CXW4 affinity chromatography technology 23649778 physical association X 2 P48510 P35979 affinity chromatography technology 23649778 physical association X 2 P48510 Q9CR57 affinity chromatography technology 23649778 physical association X 2 P48510 P35980 affinity chromatography technology 23649778 physical association X 2 P48510 P84099 affinity chromatography technology 23649778 physical association X 2 P48510 P67984 affinity chromatography technology 23649778 physical association X 2 P48510 P67984 affinity chromatography technology 23649778 physical association X 2 P48510 P62830 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 P61358 affinity chromatography technology 23649778 physical association X 2 P48510 P14115 affinity chromatography technology 23649778 physical association X 2 P48510 P62911 affinity chromatography technology 23649778 physical association X 2 P48510 Q9D1R9 affinity chromatography technology 23649778 physical association X 2 P48510 Q9D1R9 affinity chromatography technology 23649778 physical association X 2 P48510 Q9D1R9 affinity chromatography technology 23649778 physical association X 2 P48510 P47911 affinity chromatography technology 23649778 physical association X 2 P48510 P14148 affinity chromatography technology 23649778 physical association X 2 P48510 P62264 affinity chromatography technology 23649778 physical association X 2 P48510 P63276 affinity chromatography technology 23649778 physical association X 2 P48510 P25444 affinity chromatography technology 23649778 physical association X 2 P48510 P62267 affinity chromatography technology 23649778 physical association X 2 P48510 Q6ZWY3 affinity chromatography technology 23649778 physical association X 2 P48510 P62908 affinity chromatography technology 23649778 physical association X 2 P48510 Q91V55 affinity chromatography technology 23649778 physical association X 2 P48510 Q6P5B0 affinity chromatography technology 23649778 physical association X 2 P48510 Q52KI8-2 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q8BMA6 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 P32067 affinity chromatography technology 23649778 physical association X 2 P48510 Q8VEM8 affinity chromatography technology 23649778 physical association X 2 P48510 Q8R0X7 affinity chromatography technology 23649778 physical association X 2 P48510 Q01853 affinity chromatography technology 23649778 physical association X 2 P48510 Q61510 affinity chromatography technology 23649778 physical association X 2 P48510 Q62318 affinity chromatography technology 23649778 physical association X 2 P48510 Q1HFZ0 affinity chromatography technology 23649778 physical association X 2 P48510 Q9CWF2 affinity chromatography technology 23649778 physical association X 2 P48510 Q03071 pull down 23993092 direct interaction X 2 P48510 P40006 two hybrid 24709957 direct interaction X 2 P48510 P40006 affinity chromatography technology 24709957 physical association X 2 P48510 Q9HE05 pull down 20427284 direct interaction X 2 P48510 P48510 affinity chromatography technology 16140271 physical association X 2 P48510 Q04062 affinity chromatography technology 12051757 physical association X 2 P48510 P32487 affinity chromatography technology 16554755 physical association X 2 P48510 Q08412 affinity chromatography technology 16554755 physical association X 2 P48510 P48510 two hybrid 16140271 direct interaction X 2 P48510 P48510 pull down 16140271 direct interaction X 2 P48510 P47042 affinity chromatography technology 20489023 physical association X 2 P48510 P32496 affinity chromatography technology 20061387 physical association X 2 P48510 P04050 affinity chromatography technology 21211725 physical association X 2 P48510 Q9BWJ1 pull down 21378313 direct interaction X 2 P20152 P48510 affinity chromatography technology 23649778 physical association X 2 Q9D0I9 P48510 affinity chromatography technology 23649778 physical association X 2 O35972 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 Q6ZWY9 P48510 affinity chromatography technology 23649778 physical association X 2 Q6ZWY9 P48510 affinity chromatography technology 23649778 physical association X 2 Q6ZWY9 P48510 affinity chromatography technology 23649778 physical association X 2 Q8C3J5 P48510 affinity chromatography technology 23649778 physical association X 2 P62281 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P34222 P48510 two hybrid 17082762 direct interaction X 2 P34222 P48510 pull down 17082762 direct interaction X 2 P34222 P48510 two hybrid 17082762 direct interaction X 2 P34222 P48510 affinity chromatography technology 17082762 physical association X 2 P34222 P48510 affinity chromatography technology 17082762 physical association X 2 P34222 P48510 two hybrid 18719252 direct interaction X 2 P48510 P38764 affinity chromatography technology 22318722 physical association X 2 P48510 P38886 affinity chromatography technology 20059542 physical association X 2 P48510 O13563 affinity chromatography technology 20059542 physical association X 2 P48510 P55036 affinity chromatography technology 20059542 physical association X 2 P48510 P38886 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O48726 affinity chromatography technology 20059542 physical association X 2 P48510 P33297 affinity chromatography technology 12200120 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q9EST5 affinity chromatography technology 23649778 physical association X 2 P48510 O54774 affinity chromatography technology 23649778 physical association X 2 P48510 Q8CGC7 affinity chromatography technology 23649778 physical association X 2 P48510 Q8CIE6 affinity chromatography technology 23649778 physical association X 2 P48510 Q9JKB3-2 affinity chromatography technology 23649778 physical association X 2 P48510 Q8BTS0 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 P17182 affinity chromatography technology 23649778 physical association X 2 P48510 P17182 affinity chromatography technology 23649778 physical association X 2 P48510 Q8CI11 affinity chromatography technology 23649778 physical association X 2 P48510 P17156 affinity chromatography technology 23649778 physical association X 2 P48510 P07901 affinity chromatography technology 23649778 physical association X 2 P48510 Q9CX86 affinity chromatography technology 23649778 physical association X 2 P48510 P70333 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q99N69 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q9CQF0 affinity chromatography technology 23649778 physical association X 2 P48510 Q9DB15 affinity chromatography technology 23649778 physical association X 2 P48510 Q8BU88 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q8BK72 affinity chromatography technology 23649778 physical association X 2 P48510 Q9D7N3 affinity chromatography technology 23649778 physical association X 2 P48510 Q7TPV4 affinity chromatography technology 23649778 physical association X 2 P48510 E9Q634 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q9D6Z1 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q14C51 affinity chromatography technology 23649778 physical association X 2 P48510 Q6S385 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 P29341 affinity chromatography technology 23649778 physical association X 2 P48510 P17918 affinity chromatography technology 23649778 physical association X 2 P48510 P62192 affinity chromatography technology 23649778 physical association X 2 P48510 Q8VDM4 affinity chromatography technology 23649778 physical association X 2 P48510 P52480 affinity chromatography technology 23649778 physical association X 2 P48510 Q9JKF1 affinity chromatography technology 23649778 physical association X 2 P48510 Q05144 affinity chromatography technology 23649778 physical association X 2 P48510 P99027 affinity chromatography technology 23649778 physical association X 2 P48510 P14869 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 P62717 affinity chromatography technology 23649778 physical association X 2 P48510 Q9CQM8 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 P27659 affinity chromatography technology 23649778 physical association X 2 P48510 Q6ZWV7 affinity chromatography technology 23649778 physical association X 2 P48510 P83882 affinity chromatography technology 23649778 physical association X 2 P48510 P83882 affinity chromatography technology 23649778 physical association X 2 P48510 Q52KP0 affinity chromatography technology 23649778 physical association X 2 P48510 Q9D8E6 affinity chromatography technology 23649778 physical association X 2 P48510 Q3TKR5 affinity chromatography technology 23649778 physical association X 2 P48510 P12970 affinity chromatography technology 23649778 physical association X 2 P48510 P62849-2 affinity chromatography technology 23649778 physical association X 2 P48510 P62849 affinity chromatography technology 23649778 physical association X 2 P48510 P62852 affinity chromatography technology 23649778 physical association X 2 P48510 P62855 affinity chromatography technology 23649778 physical association X 2 P48510 Q6ZWU9 affinity chromatography technology 23649778 physical association X 2 P48510 Q6ZWU9 affinity chromatography technology 23649778 physical association X 2 P48510 P62754 affinity chromatography technology 23649778 physical association X 2 P48510 P62754 affinity chromatography technology 23649778 physical association X 2 P48510 Q6ZWN5 affinity chromatography technology 23649778 physical association X 2 P48510 Q8CAB9 affinity chromatography technology 23649778 physical association X 2 P48510 Q3V132 affinity chromatography technology 23649778 physical association X 2 P48510 P84104 affinity chromatography technology 23649778 physical association X 2 P48510 P38647 affinity chromatography technology 23649778 physical association X 2 P48510 Q7TMK9-2 affinity chromatography technology 23649778 physical association X 2 P48510 P05213 affinity chromatography technology 23649778 physical association X 2 P48510 P99024 affinity chromatography technology 23649778 physical association X 2 P48510 Q9ERD7 affinity chromatography technology 23649778 physical association X 2 P48510 A2AFQ0 affinity chromatography technology 23649778 physical association X 2 P48510 P62984 affinity chromatography technology 23649778 physical association X 2 P48510 P62960 affinity chromatography technology 23649778 physical association X 2 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 Q3UPF5 affinity chromatography technology 23649778 physical association X 2 P48510 P33299 affinity chromatography technology 11805328 physical association X 2 P48510 P54860 affinity chromatography technology 15652483 physical association X 2 P48510 P53861 pull down 23993092 direct interaction X 2 P48510 P54860 x-ray crystallography 20427284 association X 2 P48510 P43588 affinity chromatography technology 16284124 physical association X 2 P48510 P38886 pull down 17082762 direct interaction X 2 P48510 P33299 pull down 17082762 direct interaction X 2 P48510 P33298 pull down 17082762 direct interaction X 2 P48510 P33299 affinity chromatography technology 17082762 physical association X 2 P48510 P33297 pull down 21627799 direct interaction X 2 P48510 Q03919 affinity chromatography technology 23105008 physical association X 2 P48510 P39991 affinity chromatography technology 16554755 physical association X 2 P48510 Q12428 affinity chromatography technology 16554755 physical association X 2 P48510 P54860 biochemical 16427015 association X 2 P48510 P38886 pull down 17082762 direct interaction X 2 P48510 P54860 two hybrid 18719252 direct interaction X 2 P48510 P43582 two hybrid 18719252 direct interaction X 2 P48510 P38886 affinity chromatography technology 18995839 physical association X 2 P48510 P33299 affinity chromatography technology 18995839 physical association X 2 P48510 P38886 far western blotting 18995839 direct interaction X 2 P48510 P38886 two hybrid 18995839 direct interaction X 2 P48510 P43588 affinity chromatography technology 18757749 physical association X 2 P48510 P54860 two hybrid 16338354 direct interaction X 2 P48510 P43588 affinity chromatography technology 20170199 physical association X 2 P48510 P54860 pull down 20427284 direct interaction X 2 P48510 P32485 affinity chromatography technology 20489023 physical association X 2 P48510 P40484 affinity chromatography technology 20489023 physical association X 2 P48510 P06784 affinity chromatography technology 20489023 physical association X 2 P48510 P38886 pull down 20064467 direct interaction X 2 P48510 P22141 affinity chromatography technology 20061387 physical association X 2 P48510 P33299 affinity chromatography technology 20061387 physical association X 2 P48510 P43588 affinity chromatography technology 20061387 physical association X 2 P48510 P17157 enzymatic study 16319894 direct interaction X 2 P48510 P38764 two hybrid 21627799 direct interaction X 2 P48510 P43588 affinity chromatography technology 21627799 physical association X 2 P48510 P54860 affinity chromatography technology 11805837 physical association X 2 P48510 P14672 pull down 20854370 direct interaction X 2 P48510 O88498 pull down 21378313 direct interaction X 2 Q8BP67 P48510 affinity chromatography technology 23649778 physical association X 2 P48510 P05759 two hybrid 11805121 direct interaction X 2 P48510 P05759 nuclear magnetic resonance 15837191 direct interaction X 2 P48510 P05759 surface plasmon resonance 15837191 direct interaction X 2 P48510 P05759 pull down 16007098 direct interaction X 2 P48510 P32628 two hybrid 11805121 physical association X 2 P48510 Q04062 affinity chromatography technology 12200120 physical association X 2 P48510 Q04062 coimmunoprecipitation 12200120 physical association X 2 P48510 anti tag coimmunoprecipitation 11805837 - C 9 P48510 anti tag coimmunoprecipitation 11805837 - C 12 P48510 P53834 two hybrid pooling approach 11283351 physical association X 2 P48510 P54860 anti tag coimmunoprecipitation 11805837 physical association X 2 P48510 P38764 cross-linking study 12200120 direct interaction X 2 P48510 P38764 biochemical 12198498 direct interaction X 2 P48510 P33297 affinity chromatography technology 12200120 physical association X 2 P48510 P33297 coimmunoprecipitation 12200120 physical association X 2 P48510 P32565 cross-linking study 12200120 direct interaction X 2 P48510 anti tag coimmunoprecipitation 20489023 association C 24 P48510 molecular sieving 17082762 colocalization C 3 P48510 anti tag coimmunoprecipitation 20489023 association C 10 P48510 anti tag coimmunoprecipitation 20489023 association C 9 P48510 affinity chromatography technology 16284124 association C 99 P0CG63 P48510 pull down 11805328 physical association X 2 P0CG63 P48510 pull down 11805328 physical association X 2 P0CG63 P48510 pull down 11805328 physical association X 2 P0CG63 P48510 two hybrid 11805328 physical association X 2 P0CG63 P48510 pull down 17082762 physical association X 2 P0CG63 P48510 pull down 17082762 direct interaction X 2 P0CG63 P48510 two hybrid 20059542 physical association X 2 P48510 Q02159 two hybrid array 14690591 physical association X 2 P48510 Q08412 tandem affinity purification 16554755 physical association X 2 P48510 P32487 tandem affinity purification 16554755 physical association X 2 P48510 P10591 tandem affinity purification 19536198 association X 2 P48510 P11484 tandem affinity purification 19536198 association X 2 P48510 P0CG48 pull down 20059542 direct interaction X 2 P48510 P0CG48 pull down 20059542 direct interaction X 2 P48510 P55034 pull down 20059542 direct interaction X 2 P48510 Q16186 pull down 20059542 direct interaction X 2 P48510 Q16186 pull down 20059542 direct interaction X 2 P48510 Q16186 pull down 20059542 direct interaction X 2 P48510 Q16186 pull down 20059542 direct interaction X 2 P48510 anti tag coimmunoprecipitation 11805837 association C 9 P48510 tandem affinity purification 20489023 association C 11 P48510 inferred by author 16554755 association C 3 P48510 tandem affinity purification 20489023 association C 13 P34222 P48510 pull down 17082762 direct interaction X 2 P34222 P48510 pull down 17082762 physical association X 2 P34222 P48510 pull down 17082762 physical association X 2 P34222 P48510 pull down 17082762 physical association X 2 P34222 P48510 pull down 17082762 physical association X 2 P34222 P48510 pull down 17082762 physical association X 2 P34222 P48510 anti tag coimmunoprecipitation 17082762 physical association X 2 P34222 P48510 two hybrid 17082762 physical association X 2 P34222 P48510 two hybrid 17082762 physical association X 2 P34222 P48510 two hybrid 18719252 physical association X 2 P48510 Q03707 two hybrid 10688190 physical association X 2 P48510 P53834 two hybrid fragment pooling approach 11283351 physical association X 2 P48510 P33299 pull down 11805328 physical association X 2 P48510 Q12428 tandem affinity purification 16554755 physical association X 2 P48510 P39991 tandem affinity purification 16554755 physical association X 2 P48510 P33299 pull down 16712842 physical association X 2 P48510 Q01939 pull down 16712842 physical association X 2 P48510 P22141 pull down 16712842 physical association X 2 P48510 P38886 pull down 17082762 direct interaction X 2 P48510 P33299 pull down 17082762 physical association X 2 P48510 P33298 pull down 17082762 physical association X 2 P48510 P33299 anti tag coimmunoprecipitation 17082762 physical association X 2 P48510 P43582 two hybrid 18719252 physical association X 2 P48510 P54860 two hybrid 18719252 physical association X 2 P48510 P38886 pull down 20059542 direct interaction X 2 P48510 P38886 pull down 20059542 direct interaction X 2 P48510 P38886 pull down 20059542 direct interaction X 2 P48510 P38886 pull down 20059542 direct interaction X 2 P48510 P55036 pull down 20059542 direct interaction X 2 P48510 P55036 pull down 20059542 direct interaction X 2 P48510 P38886 pull down 20059542 direct interaction X 2 P48510 O48726 pull down 20059542 direct interaction X 2 P48510 O48726 pull down 20059542 direct interaction X 2 P48510 P38886 two hybrid 20059542 physical association X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O48726 pull down 20059542 direct interaction X 2 P48510 O48726 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 O13563 pull down 20059542 direct interaction X 2 P48510 P32628 interaction detection method 8682868 - X 2 P48510 mass spectrometry studies of complexes 11805837 - C 10 P48510 P53834 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality RPS31 DSK2 15837191,15837191,11805121,11805328 0107,0077,0018,0018 LC UBI4 DSK2 16140271,11805328,11805121,20059542,16140271,15837191,11805328,15837191 0401,0018,0018,0018,0096,0096,0096,0114 LC RPL40A DSK2 11805328 0018 LC PHO85 DSK2 16319894 0415 LC RPN2 DSK2 12200120 0030 LC RAD23 DSK2 11805121,17082762 0018,0071 LC RPT5 DSK2 12200120,12200120 0004,0019 LC PTH2 DSK2 18719252,17082762,17082762,17082762,17082762,17082762 0018,0071,0004,0018,0007,0096 HT,LC RPN1 DSK2 21627799,12198498,12200120 0018,0401,0030 LC RPN10 DSK2 20059542,20059542,18995839,18995839,18995839,20059542 0096,0018,0047,0004,0018,0004 LC IRC22 DSK2 24709957,24709957 0004,0018 LC WWM1 DSK2 18719252 0018 HT DSK2 DSK2 16421449,16140271,16140271,16140271 0114,0096,0018,0004 LC DSK2 HCH1 11283351,11283351,11283351 0018,0399,0398 HT DSK2 UFD2 16427015,18719252,20427284,16338354,20427284,20427284 0401,0018,0004,0018,0096,0114 LC,HT DSK2 UBC7 14690591 0397 LC DSK2 SRC1 10688190 0018 HT DSK2 RPN9 12200120,12200120 0004,0019 LC RPN13 DSK2 20059542,20059542 0096,0004 LC RPO21 DSK2 21211725,23056298 0004,0004 LC STE7 DSK2 20489023,20489023 0007,0004 HT UBI4 DSK2 16140271,11805328,12051757,19620964,21763274,17082762,23649778,23649778,24709957,16140271,15837191,11805328,17082762,17198374,15242647,22106047,15837191 0401,0018,0096,0096,0004,0004,0004,0096,0004,0096,0096,0096,0096,0096,0096,0004,0114 LC SSA1 DSK2 19536198 0676 HT SSB1 DSK2 19536198 0676 HT PRE1 DSK2 20061387,16712842 0004,0096 LC HOG1 DSK2 20489023,20489023,20489023 0007,0676,0004 HT LYP1 DSK2 16554755,16554755,16554755 0363,0676,0004 HT RPN12 DSK2 20061387 0004 LC RPT5 DSK2 21627799,12200120,21627799,12200120 0096,0004,0004,0019 LC RPT3 DSK2 17082762,17082762 0096,0004 LC RPT1 DSK2 11805328,17082762,17082762,20061387,18995839,16712842,11805328,17082762 0004,0007,0004,0004,0004,0096,0096,0096 LC PTH2 DSK2 17082762,17082762,17082762,17082762,17082762 0071,0004,0018,0007,0096 LC SIC1 DSK2 15242647 0004 LC GND1 DSK2 16284124 0004 LC RPN1 DSK2 22318722,12198498 0004,0401 LC RPN10 DSK2 20059542,26450923,20059542,18995839,17082762,18995839,18995839,20059542,20064467,17082762 0096,0096,0018,0047,0004,0004,0018,0004,0096,0096 LC P39991 DSK2 16554755,16554755 0676,0004 HT IRC22 DSK2 24709957,24709957 0004,0018 LC MOB1 DSK2 20489023,20489023 0007,0004 HT RPN11 DSK2 16284124,26450923,20170199,21627799,20061387,26450923,18757749 0004,0096,0004,0004,0004,0004,0004 LC,HT IKS1 DSK2 20489023,20489023 0007,0004 HT DSK2 DSK2 16140271,16140271,16140271 0096,0018,0004 LC DSK2 ELA1 23993092 0096 LC DSK2 UFD2 16427015,11805837,20427284,20427284,20427284,15652483,11805837 0401,0004,0004,0096,0114,0004,0007 LC,HT DSK2 SLT2 20489023,20489023,20489023 0007,0676,0004 HT DSK2 RPT6 16712842 0096 LC DSK2 ELC1 23993092 0096 LC DSK2 RUB1 23105008 0096 LC DSK2 RPN9 12200120,12200120,12051757 0004,0019,0004 LC DSK2 MMS22 26849847 0004 LC DSK2 CUE5 16554755,16554755 0676,0004 HT DSK2 PDH1 16554755,16554755,16554755 0363,0676,0004 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q12221 P48510 PUF2 DSK2 0.126 26668354 Q12428 P48510 PDH1 DSK2 0.332 16554755 P48510 P17157 DSK2 PHO85 0.183 16319894 Q9HE05 P48510 UFD2 DSK2 0.309 20427284 P48510 P25567 DSK2 SRO9 0.126 22271760 P48510 P10591 DSK2 SSA1 0.126 19536198 P48510 P0CG48 DSK2 UBC 0.597 20059542,16799550,23801757 Q04062 P48510 RPN9 DSK2 0.416 12200120,12051757 P48510 P22141 DSK2 PRE1 0.309 16712842,20061387 P48510 P38764 DSK2 RPN1 0.636 21627799,12198498,12200120,22318722 P48510 P33298 DSK2 RPT3 0.286 17082762 P48510 P33297 DSK2 RPT5 0.454 12200120,21627799 P48510 P04050 DSK2 RPO21 0.376 21211725,23056298 P48510 P14672 DSK2 SLC2A4 0.523 23424197,20854370 P48510 P43582 DSK2 WWM1 0.332 18719252 P48510 P40006 DSK2 IRC22 0.454 24709957 P48510 P39991 DSK2 P39991 0.236 16554755 P61864 P48510 RPL40A DSK2 0.539 11805121,15837191 P48510 P33299 DSK2 RPT1 0.814 11805328,17082762,16712842,20061387,18995839 P48510 P34222 DSK2 PTH2 0.86 17082762,18719252 P48510 P38886 DSK2 RPN10 0.943 26450923,17082762,20059542,20064467,18995839 P48510 P0CG63 DSK2 UBI4 0.997 11805121,20059542,15242647,12051757,17198374,23649778,16140271,15837191,11805328,17082762,19620964,24709957 P48510 P38199 DSK2 HEK2 0.126 18805955 P48510 P32487 DSK2 LYP1 0.332 16554755 P48510 P38720 DSK2 GND1 0.126 16284124 P48510 P32628 DSK2 RAD23 0.111 11805121,17082762 P48510 P40484 DSK2 MOB1 0.286 20489023 P48510 O14641 DSK2 DVL2 0.332 27107014 P48510 O48726 DSK2 RPN13 0.286 20059542 P48510 O88498 DSK2 BCL2L11 0.309 21378313 P48510 P06784 DSK2 STE7 0.332 20489023 P48510 P11484 DSK2 SSB1 0.126 19536198 P48510 P27361 DSK2 MAPK3 0.309 21378313 P48510 P32485 DSK2 HOG1 0.332 20489023 P48510 P32496 DSK2 RPN12 0.21 20061387 P48510 P32565 DSK2 RPN2 0.309 12200120 P48510 P43588 DSK2 RPN11 0.772 26450923,20061387,20170199,21627799,18757749,16284124 P48510 P47042 DSK2 IKS1 0.332 20489023 P48510 P48510 DSK2 DSK2 0.236 16140271 P53861 P48510 ELA1 DSK2 0.309 23993092 P54860 P48510 UFD2 DSK2 0.876 20427284,15652483,16338354,18719252,11805837 P55034 P48510 RPN10 DSK2 0.286 20059542 Q00772 P48510 SLT2 DSK2 0.332 20489023 Q01939 P48510 RPT6 DSK2 0.126 16712842 Q02159 P48510 UBC7 DSK2 0.126 14690591 Q03071 P48510 ELC1 DSK2 0.309 23993092 Q03707 P48510 SRC1 DSK2 0.183 10688190 Q08412 P48510 CUE5 DSK2 0.236 16554755 Q16186 P48510 ADRM1 DSK2 0.416 20059542 Q07468 P48510 VAM6 DSK2 0.126 25026036 Q03919 P48510 RUB1 DSK2 0.309 23105008 P48510 O13563 DSK2 RPN13 0.416 20059542 P55036 P48510 PSMD4 DSK2 0.416 20059542 P53834 P48510 HCH1 DSK2 0.21 11283351