PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus MRP2 FAP1 16554755 intact exp Uncharacterized glycosyl hydrolase YIR007W FAP1 16554755 biogrid,i2d,mint,intact exp FAP1 RPS22B 16429126 intact exp RPS22A FAP1 16429126 intact exp YDJ1 FAP1 19536198 intact exp RPL17B FAP1 16429126 intact exp MLC1 FAP1 16554755 biogrid,i2d,mint,intact exp SSA3 FAP1 19536198 intact exp SSB1 FAP1 19536198 biogrid,intact exp ECM10 FAP1 19536198 intact exp SCJ1 FAP1 19536198 intact exp MYO2 FAP1 16554755 biogrid,i2d,mint,intact exp SSB2 FAP1 23332755,19536198 biogrid,intact exp FPR1 FAP1 11805826,16429126,16554755,10998178,11805837 biogrid,i2d,mint,intact,dip exp IMD3 FAP1 16429126 biogrid,intact exp SSE1 FAP1 19536198 intact exp RPL2A FAP1 16429126 intact exp FAP1 HSP42 19536198 intact exp CCT3 FAP1 18511909 biogrid exp CMD1 FAP1 i2d exp BBC1 FAP1 11743162 biogrid,i2d,mint,intact,dip exp RPL4A FAP1 16429126 biogrid,intact exp RPS8A FAP1 16429126 intact exp SSA2 FAP1 19536198 intact exp CDC27 FAP1 16429126 intact exp HSP78 FAP1 19536198 intact exp SKT5 FAP1 16429126 intact exp FAP1 VAM6 25026036 biogrid exp ARG3 FAP1 11805837 dip exp SSA1 FAP1 19536198 intact exp FAP1 CIA1 14690591 i2d,intact exp FAP1 FAP1 11967834, 23023127 biogrid,dip exp, ortho, pred FAP1 SDO1 14690591, 23023127 i2d,intact exp, pred RPP0 FAP1 16429126, 23023127 biogrid,intact exp, pred NOP1 FAP1 16554755, 23023127 biogrid,i2d,mint,intact exp, pred FAP1 PRP11 9207794, 23023127 biogrid,i2d,dip exp, pred TEF4 FAP1 11805826, 23023127 biogrid,mint,intact,dip exp, pred Uncharacterized protein YIL161W FAP1 16429126,16554755, 23023127 biogrid,i2d,mint,intact exp, pred RPL7A FAP1 16429126, 23023127 biogrid,intact exp, pred RPL5 FAP1 16429126, 23023127 biogrid,intact exp, pred RPS0A FAP1 16429126, 23023127 biogrid,intact exp, pred SHE2 FAP1 10688190, 23023127 biogrid,i2d,mint,intact,dip exp, pred MRE11 FAP1 10688190, 23023127 biogrid,i2d,mint,intact,dip exp, pred RPL3 FAP1 ortho DBP2 FAP1 ortho RPL22A FAP1 ortho UBC4 FAP1 ortho SEC23 FAP1 ortho CRM1 FAP1 ortho FAP1 MEX67 ortho SHM1 FAP1 ortho FAP1 SDH1 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P53971 - 11805826 - C 11 P53971 - 11805826 - C 4 P53971 P32829 - 10688190 - X 2 P53971 P36068 - 10688190 - X 2 P20081 P53971 - 11805837 - X 2 P53971 Q05583 - 14690591 - X 2 P53971 Q07350 - 9207794 - X 2 P53971 Q07953 - 14690591 - X 2 P47068 P53971 - 11743162 - X 2 P39077 P53971 affinity chromatography technology 18511909 physical association X 2 P0CG63 P53971 biochemical 23583075 association X 2 P0CG63 P53971 affinity chromatography technology 23793018 physical association X 2 P53971 P53971 unspecified method 11967834 direct interaction X 2 P53971 P40150 biochemical 23332755 association X 2 P53971 P40449 affinity chromatography technology 16554755 physical association X 2 P53971 P15646 affinity chromatography technology 16554755 physical association X 2 P53971 P19524 affinity chromatography technology 16554755 physical association X 2 P53971 P40566 affinity chromatography technology 16554755 physical association X 2 P53971 P40449 affinity chromatography technology 16429126 physical association X 2 P53971 P05737 affinity chromatography technology 16429126 physical association X 2 P53971 P05317 affinity chromatography technology 16429126 physical association X 2 P53971 P40449 affinity chromatography technology 16429126 physical association X 2 P53971 P40449 affinity chromatography technology 17200106 physical association X 2 P53971 P32829 two hybrid 10688190 direct interaction X 2 P53971 P36068 two hybrid 10688190 direct interaction X 2 P20081 P53971 two hybrid 10998178 direct interaction X 2 P20081 P53971 imaging technique 10998178 colocalization X 2 P20081 P53971 affinity chromatography technology 17200106 physical association X 2 P20081 P53971 affinity chromatography technology 11805826 physical association X 2 P20081 P53971 affinity chromatography technology 11805837 physical association X 2 P32905 P53971 affinity chromatography technology 16429126 physical association X 2 P53971 Q07350 two hybrid 9207794 direct interaction X 2 P53971 P53141 affinity chromatography technology 16554755 physical association X 2 P53971 P50095 affinity chromatography technology 16429126 physical association X 2 P53971 P10664 affinity chromatography technology 16429126 physical association X 2 P53971 P26321 affinity chromatography technology 16429126 physical association X 2 P53971 P11484 affinity chromatography technology 19536198 physical association X 2 P53971 P11484 affinity chromatography technology 19536198 physical association X 2 P53971 P36008 affinity chromatography technology 11805826 physical association X 2 P47068 P53971 two hybrid 11743162 direct interaction X 2 P53971 anti tag coimmunoprecipitation 11805837 - C 3 P53971 tandem affinity purification 11805826 - C 4 P53971 inferred by author 11805826 physical association C 14 P53971 tandem affinity purification 11805826 - C 11 P53971 P32829 two hybrid 10688190 physical association X 2 P53971 P36068 two hybrid 10688190 physical association X 2 P53971 inferred by author 11805826 physical association C 14 P20081 P53971 anti tag coimmunoprecipitation 11805837 physical association X 2 P20081 P53971 tandem affinity purification 11805826 physical association X 2 P53971 P05150 anti tag coimmunoprecipitation 11805837 physical association X 2 P53971 Q07350 two hybrid 9207794 physical association X 2 P53971 P36008 tandem affinity purification 11805826 physical association X 2 P53971 P53971 phage display 11967834 physical association Y 1 P47068 P53971 two hybrid 11743162 physical association X 2 P53971 tandem affinity purification 16429126 association C 9 P53971 tandem affinity purification 16429126 association C 26 P32589 P53971 tandem affinity purification 19536198 association X 2 P25303 P53971 tandem affinity purification 19536198 association X 2 P10591 P53971 tandem affinity purification 19536198 association X 2 P53971 P32829 two hybrid 10688190 physical association X 2 P53971 P36068 two hybrid 10688190 physical association X 2 P53971 P40566 tandem affinity purification 16554755 physical association X 2 P53971 P40449 tandem affinity purification 16554755 physical association X 2 P53971 P19524 tandem affinity purification 16554755 physical association X 2 P53971 P15646 tandem affinity purification 16554755 physical association X 2 P53971 P19524 tandem affinity purification 16554755 physical association X 2 P53971 P19524 tandem affinity purification 16554755 physical association X 2 P53971 P19524 tandem affinity purification 16554755 physical association X 2 P53971 P19524 tandem affinity purification 16554755 physical association X 2 P53971 P40449 tandem affinity purification 16554755 physical association X 2 P53971 P40449 tandem affinity purification 16554755 physical association X 2 P53971 P15646 tandem affinity purification 16554755 physical association X 2 P53971 P19524 tandem affinity purification 16554755 physical association X 2 P53971 P10592 tandem affinity purification 19536198 association X 2 P53971 P40150 tandem affinity purification 19536198 association X 2 P53971 P33416 tandem affinity purification 19536198 association X 2 P53971 P39987 tandem affinity purification 19536198 association X 2 P53971 tandem affinity purification 11805826 association C 5 P53971 tandem affinity purification 16429126 association C 8 P53971 inferred by author 16429126 physical association C 14 P53971 inferred by author 16429126 physical association C 9 P53971 inferred by author 16554755 association C 4 P53971 tandem affinity purification 11805826 association C 12 P20081 P53971 anti tag coimmunoprecipitation 11805837 physical association X 2 P53971 Q07953 two hybrid array 14690591 physical association X 2 P53971 Q05583 two hybrid array 14690591 physical association X 2 P53971 P53141 tandem affinity purification 16554755 physical association X 2 P53971 P11484 tandem affinity purification 19536198 association X 2 P53971 P25491 tandem affinity purification 19536198 association X 2 P53971 Q12329 tandem affinity purification 19536198 association X 2 P53971 P09435 tandem affinity purification 19536198 association X 2 P53971 P11484 tandem affinity purification 19536198 association X 2 P47068 P53971 two hybrid 11743162 physical association X 2 P53971 mass spectrometry studies of complexes 11805826 - C 18 P53971 P36068 two hybrid 10688190 - X 2 P53971 P32829 two hybrid 10688190 - X 2 P53971 mass spectrometry studies of complexes 11805837 - C 3 P53971 mass spectrometry studies of complexes 11805837 - C 3 P53971 mass spectrometry studies of complexes 11805826 - C 15 P53971 Q07350 two hybrid 9207794 - X 2 P47068 P53971 two hybrid 11743162 - X 2

PPI - HINT Gene A Gene B PMID Method Quality FPR1 FAP1 10998178,10998178 0428,0018 LC MRE11 FAP1 10688190,10688190 0397,0018 HT SHE2 FAP1 10688190,10688190 0397,0018 HT SSB2 FAP1 23332755 0401 LC BBC1 FAP1 11743162,11743162 0397,0018 HT FAP1 FAP1 11967834 0084 LC FAP1 CIA1 14690591,14690591 0018,0397 LC FAP1 PRP11 9207794 0018 HT FAP1 SDO1 14690591,14690591 0018,0397 LC ARG3 FAP1 11805837 0007 HT RPP0 FAP1 16429126,16429126,16429126 0676,0004,0363 HT RPL7A FAP1 16429126,16429126,16429126 0676,0004,0363 HT SSA3 FAP1 19536198 0676 HT RPS22A FAP1 16429126 0363 HT RPS8A FAP1 16429126 0363 HT RPL2B FAP1 16429126 0363 HT SSA1 FAP1 19536198 0676 HT SSA2 FAP1 19536198 0676 HT MRP2 FAP1 16554755 0363 HT RPL4A FAP1 16429126,16429126,16429126 0676,0004,0363 HT SSB1 FAP1 19536198,19536198 0004,0676 HT NOP1 FAP1 16554755,16554755 0676,0004 HT MYO2 FAP1 16554755,16554755 0676,0004 HT FPR1 FAP1 11805837,10998178,16554755,16429126,11805826,11805826,10998178,17200106,11805826,11805837 0004,0428,0363,0676,0004,0676,0018,0004,0007,0007 HT,LC SCJ1 FAP1 19536198 0676 HT YDJ1 FAP1 19536198 0676 HT RPL5 FAP1 16429126,16429126,16429126 0676,0004,0363 HT SSE1 FAP1 19536198 0676 HT RPS0A FAP1 16429126,16429126,16429126 0676,0004,0363 HT HSP78 FAP1 19536198 0676 HT SKT5 FAP1 16429126 0363 HT TEF4 FAP1 11805826,11805826,11805826 0676,0007,0004 HT CDC27 FAP1 16429126 0363 HT CCT3 FAP1 18511909 0004 LC ECM10 FAP1 19536198 0676 HT SSB2 FAP1 19536198,23332755 0676,0401 HT,LC P40449 FAP1 16554755,16554755,16429126,16554755,17200106,16429126,16429126 0363,0004,0676,0676,0004,0004,0363 HT P40566 FAP1 16554755,16554755 0676,0004 HT RPL17B FAP1 16429126 0363 HT IMD3 FAP1 16429126,16429126,16429126 0676,0004,0363 HT MLC1 FAP1 16554755,16554755 0676,0004 HT FAP1 HSP42 19536198 0676 HT FAP1 RPS22B 16429126 0363 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53971 P10592 FAP1 SSA2 0.126 19536198 P53971 P05150 FAP1 ARG3 0.126 11805837 P53971 P20081 FAP1 FPR1 0.583 11805826,16429126,16554755,11805837 P53971 P40150 FAP1 SSB2 0.236 23332755,19536198 P53971 P32905 FAP1 RPS0A 0.332 16429126 P53971 P26321 FAP1 RPL5 0.332 16429126 P53971 P05737 FAP1 RPL7A 0.332 16429126 P53971 P05317 FAP1 RPP0 0.332 16429126 P53971 P10664 FAP1 RPL4A 0.332 16429126 P53971 P50095 FAP1 IMD3 0.332 16429126 P53971 P40449 FAP1 P40449 0.702 16554755,16429126 P53971 P36068 FAP1 SHE2 0.354 10688190 P53971 P38042 FAP1 CDC27 0.126 16429126 P53971 P32589 FAP1 SSE1 0.126 19536198 P53971 P39077 FAP1 CCT3 0.126 18511909 P53971 P32829 FAP1 MRE11 0.332 10688190 P53971 P36008 FAP1 TEF4 0.286 11805826 P53971 P40566 FAP1 P40566 0.236 16554755 P53971 P19524 FAP1 MYO2 0.332 16554755 P53971 P05736 FAP1 RPL2B 0.126 16429126 P53971 P05754 FAP1 RPS8B 0.126 16429126 P53971 P09435 FAP1 SSA3 0.126 19536198 P53971 P0C0W1 FAP1 RPS22A 0.126 16429126 P53971 P10591 FAP1 SSA1 0.126 19536198 P53971 P10663 FAP1 MRP2 0.126 16554755 P53971 P11484 FAP1 SSB1 0.332 19536198 P53971 P15646 FAP1 NOP1 0.236 16554755 P53971 P25303 FAP1 SCJ1 0.126 19536198 P53971 P25491 FAP1 YDJ1 0.126 19536198 P53971 P33416 FAP1 HSP78 0.126 19536198 P53971 P34226 FAP1 SKT5 0.126 16429126 P53971 P39987 FAP1 ECM10 0.126 19536198 P53971 P46990 FAP1 RPL17B 0.126 16429126 P53971 P47068 FAP1 BBC1 0.183 11743162 P53971 P53141 FAP1 MLC1 0.236 16554755 P53971 P53971 FAP1 FAP1 0.065 11967834 Q05583 P53971 CIA1 FAP1 0.126 14690591 Q07350 P53971 PRP11 FAP1 0.033 9207794 Q07953 P53971 SDO1 FAP1 0.126 14690591 Q12329 P53971 HSP42 FAP1 0.126 19536198 Q3E7Y3 P53971 RPS22B FAP1 0.126 16429126