PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus IPI3 IRC20 14690591 intact exp MCM3 IPI3 22421151 biogrid exp IPI3 MAK10 14690591 intact exp IPI3 RLF2 22875988 biogrid exp COY1 IPI3 22875988 biogrid exp IPI3 RRP12 i2d exp ORC2 IPI3 22421151 biogrid exp IPI3 HHT1, HHT2 22199229 biogrid exp CDC3 IPI3 22875988 biogrid exp IPI3 YAP6 22875988 biogrid exp YDJ1 IPI3 11805837 dip exp IPI3 VAM6 25026036 biogrid exp SPB4 IPI3 21825077 biogrid exp HSP78 IPI3 19536198 intact exp NSA2 IPI3 i2d exp ALG5 IPI3 18467557 biogrid,i2d,mint,intact exp TSC11 IPI3 22875988 biogrid exp ATG1 IPI3 16319894,22875988 biogrid,i2d exp IPI3 PUF6 i2d exp SCH9 IPI3 14690591 intact exp MET28 IPI3 14690591 intact exp LAT1 IPI3 11805837 dip exp SSA1 IPI3 19536198 intact exp IPI3 ORC1 22421151 biogrid exp CDC6 IPI3 22421151 biogrid exp RPF2 IPI3 i2d exp TUB1 IPI3 11805837 dip exp IPI3 PUF3 26493364 biogrid exp IPI3 SHE9 22875988 biogrid exp IPI3 ORC3 22421151 biogrid exp IPI3 SPR6 14690591 i2d,intact exp KSP1 IPI3 16319894 biogrid,i2d exp MDJ1 IPI3 11805837 dip exp IPI3 Zinc finger protein YPR022C 14690591 i2d,intact exp PHO85 IPI3 16319894 biogrid,i2d exp ATP1 IPI3 11805837 dip exp CNM67 IPI3 22875988 biogrid exp SSB2 IPI3 23332755 biogrid exp IPI3 IPI3 14690591 intact exp IPI3 RVB2 11805837 dip exp CTR1 IPI3 14690591 intact exp MCM4 IPI3 22421151 biogrid exp SKN7 IPI3 22875988 biogrid exp IPI3 NST1 22875988 biogrid exp LPD1 IPI3 11805837 dip exp LHS1 IPI3 19536198,22875988 biogrid,intact exp SNF7 IPI3 22875988 biogrid exp VMA6 IPI3 11283351 i2d,mint,intact,dip exp IPI3 NOC3 22421151 biogrid exp IPI3 BUL2 22875988 biogrid exp SSB1 IPI3 19536198 intact exp SAM1 IPI3 11805837 dip exp SPC105 IPI3 22875988 biogrid exp SSZ1 IPI3 19536198 intact exp TAH11 IPI3 22421151 biogrid exp TUB2 IPI3 11805837 dip exp TPK1 IPI3 16319894 biogrid,i2d exp KGD2 IPI3 14690591 intact exp REC107 IPI3 22875988 biogrid exp IPI3 DID2 22875988 biogrid exp NOP4 IPI3 i2d exp IRA2 IPI3 14690591 intact exp MCM2 IPI3 22421151 biogrid exp PGI1 IPI3 11805837 dip exp PEP12 IPI3 14690591 intact exp SDA1 IPI3 23142978,11805826,16429126,12374754,15260980, 23023127 biogrid,i2d,mint,intact,dip exp, pred IPI3 BUD20 11805826,16429126,23045392, 23023127 biogrid,mint,intact,dip exp, pred MRT4 IPI3 19797079, 23023127 biogrid exp, pred IPI1 IPI3 14759368,16429126,16554755,14690591, 23023127 biogrid,i2d,mint,intact exp, pred IPI3 ARX1 17803941,16429126,23045392, 23023127 biogrid,i2d,intact exp, pred IPI3 ATG17 11283351,11805837, 23023127 biogrid,i2d,mint,intact,dip exp, pred RLP7 IPI3 23945946, 23023127 biogrid,i2d exp, pred IPI3 MDN1 15260980, 23023127 biogrid,i2d exp, pred RSA4 IPI3 11805826,16429126,19737519, 23023127 biogrid,mint,intact,dip exp, pred MET30 IPI3 11283351, 23023127 i2d,mint,intact,dip exp, pred IPI3 Putative uncharacterized protein Q0032, mitochondrial 11805837, 23023127 mint,intact exp, pred LOC1 IPI3 16429126, 23023127 biogrid,intact exp, pred NUP188 IPI3 14690591, 23023127 intact exp, pred ALB1 IPI3 17803941,23045392, 23023127 biogrid exp, pred IPI3 NOG1 15260980, 23023127 biogrid,i2d exp, pred NAB3 IPI3 18467557, 23023127 biogrid,i2d,mint,intact exp, pred IPI3 NOP15 11805826,16429126,17922018, 23023127 biogrid,i2d,mint,intact,dip exp, pred NOP7 IPI3 23023127 i2d exp, pred HHF1, HHF2 IPI3 11805837, 23023127 biogrid,mint,intact,dip exp, pred IPI3 BRX1 23023127 i2d exp, pred IPI3 SRP1 11283351, 23023127 i2d,mint,intact,dip exp, pred CIC1 IPI3 16429126, 23023127 biogrid,i2d,intact exp, pred NOG2 IPI3 16429126, 23023127 biogrid,i2d,intact exp, pred RIX1 IPI3 16429126,15528184,12374754,20100801,15260980,16554755,11805837,23142978,21777812,20542003,19737519,14690591, 23023127 biogrid,i2d,mint,intact,dip exp, pred NUG1 IPI3 12374754, 23023127 biogrid,i2d exp, pred IPI3 TIF6 11805826,16429126, 23023127 biogrid,i2d,mint,intact,dip exp, pred MAK11 IPI3 23023127 pred MAK16 IPI3 23023127 pred RPF1 IPI3 23023127 pred SSF1 IPI3 23023127 pred MAK5 IPI3 23023127 pred RPL3 IPI3 23023127 pred IPI3 NOP8 23023127 pred NOC2 IPI3 23023127 pred IPI3 MRD1 23023127 pred TAF2 IPI3 23023127 pred DRS1 IPI3 23023127 pred DBP6 IPI3 23023127 pred RRP7 IPI3 23023127 pred PRP5 IPI3 23023127 pred NMD3 IPI3 23023127 pred IPI3 DBP10 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P53877 - 11805837 - C 3 P53877 - 11805826 - C 32 P53877 - 11805837 - C 4 P53877 - 11805826 - C 15 P53877 - 11805826 - C 20 P53877 - 14690591 - X 2 Q01684 P53877 - 14690591 - X 2 P39014 P53877 - 11283351 - X 2 Q12139 P53877 - 14690591 - X 2 P53877 P32366 - 11283351 - X 2 Q02821 P53877 - 11283351 - X 2 P53877 - 11805826 - C 4 P53877 - 11805826 - C 26 P53877 - 11805837 - C 5 P53877 - 14759368 - C 3 P53877 - 14690591 - C 3 P53877 Q06410 - 11283351 - X 2 P29469 P53877 affinity chromatography technology 22421151 physical association X 2 P29469 P53877 affinity chromatography technology 22421151 physical association X 2 P29469 P53877 biochemical 22421151 colocalization X 2 P38691 P53877 enzymatic study 16319894 direct interaction X 2 P39929 P53877 two hybrid 22875988 direct interaction X 2 P54790 P53877 affinity chromatography technology 22421151 physical association X 2 P54790 P53877 affinity chromatography technology 22421151 physical association X 2 P54790 P53877 biochemical 22421151 colocalization X 2 P36016 P53877 two hybrid 22875988 direct interaction X 2 P69771 P53877 two hybrid 22875988 direct interaction X 2 P53877 P53313 affinity chromatography technology 12374754 physical association X 2 P53877 P53313 affinity chromatography technology 12374754 physical association X 2 P53877 P53313 affinity chromatography technology 15260980 physical association X 2 P53877 P53313 affinity chromatography technology 15260980 physical association X 2 P53877 Q03935 two hybrid 22875988 direct interaction X 2 P53877 P53148 two hybrid 22875988 direct interaction X 2 P53877 P53104 two hybrid 22875988 direct interaction X 2 P53877 P21651 two hybrid 22875988 direct interaction X 2 P53877 P53313 biochemical 23142978 association X 2 P53877 Q08004 affinity chromatography technology 23045392 physical association X 2 P53877 Q03862 affinity chromatography technology 23045392 physical association X 2 P53877 P38803 affinity chromatography technology 16554755 physical association X 2 P53877 Q03862 affinity chromatography technology 16429126 physical association X 2 P53877 P53313 affinity chromatography technology 16429126 physical association X 2 P53877 Q08004 affinity chromatography technology 16429126 physical association X 2 P53877 P38803 affinity chromatography technology 16429126 physical association X 2 P53877 P53104 enzymatic study 16319894 direct interaction X 2 P53877 P06244 enzymatic study 16319894 direct interaction X 2 P53877 Q03862 affinity chromatography technology 17200106 physical association X 2 P53877 P53313 affinity chromatography technology 17200106 physical association X 2 P53877 P38803 affinity chromatography technology 17200106 physical association X 2 P53877 P14126 affinity chromatography technology 17200106 physical association X 2 P53877 P38996 protein complementation assay 18467557 direct interaction X 2 P53877 P17157 enzymatic study 16319894 direct interaction X 2 P53877 Q03862 affinity chromatography technology 17803941 physical association X 2 P53877 P38803 affinity chromatography technology 14690591 physical association X 2 P53877 P38803 affinity chromatography technology 14759368 physical association X 2 P53877 Q08004 affinity chromatography technology 11805826 physical association X 2 P53877 P53313 affinity chromatography technology 11805826 physical association X 2 P53877 P02309 affinity chromatography technology 11805837 physical association X 2 P53877 P61830 affinity chromatography technology 22199229 physical association X 2 P53877 P61830 affinity chromatography technology 22199229 physical association X 2 P53877 P54784 affinity chromatography technology 22421151 physical association X 2 P53877 P47112 affinity chromatography technology 22421151 physical association X 2 P53877 P47112 two hybrid 22421151 direct interaction X 2 P53877 P47112 two hybrid 22421151 direct interaction X 2 Q12522 P53877 affinity chromatography technology 16429126 physical association X 2 Q12522 P53877 affinity chromatography technology 17200106 physical association X 2 Q12522 P53877 affinity chromatography technology 11805826 physical association X 2 P24279 P53877 affinity chromatography technology 22421151 physical association X 2 P38883 P53877 affinity chromatography technology 12374754 physical association X 2 P38883 P53877 affinity chromatography technology 12374754 physical association X 2 P38883 P53877 affinity chromatography technology 15260980 physical association X 2 P38883 P53877 affinity chromatography technology 15260980 physical association X 2 P38883 P53877 biochemical 23142978 association X 2 P38883 P53877 affinity chromatography technology 15528184 physical association X 2 P38883 P53877 affinity chromatography technology 16554755 physical association X 2 P38883 P53877 affinity chromatography technology 16429126 physical association X 2 P38883 P53877 affinity chromatography technology 17200106 physical association X 2 P38883 P53877 affinity chromatography technology 19737519 physical association X 2 P38883 P53877 affinity chromatography technology 20100801 physical association X 2 P38883 P53877 affinity chromatography technology 20542003 physical association X 2 P38883 P53877 affinity chromatography technology 21777812 physical association X 2 P38883 P53877 affinity chromatography technology 11805837 physical association X 2 P32833 P53877 two hybrid 22421151 direct interaction X 2 P32833 P53877 two hybrid 22421151 direct interaction X 2 P25808 P53877 affinity chromatography technology 21825077 physical association X 2 P34237 P53877 two hybrid 22875988 direct interaction X 2 Q12389 P53877 affinity chromatography technology 17200106 physical association X 2 Q04172 P53877 two hybrid 22875988 direct interaction X 2 P40693 P53877 affinity chromatography technology 23945946 physical association X 2 P40693 P53877 affinity chromatography technology 17200106 physical association X 2 P0CG63 P53877 affinity chromatography technology 23793018 physical association X 2 P47019 P53877 affinity chromatography technology 23045392 physical association X 2 P47019 P53877 affinity chromatography technology 17803941 physical association X 2 P38889 P53877 two hybrid 22875988 direct interaction X 2 P33201 P53877 affinity chromatography technology 17200106 physical association X 2 P33201 P53877 affinity chromatography technology 19797079 physical association X 2 Q12495 P53877 two hybrid 22875988 direct interaction X 2 P53877 P40010 affinity chromatography technology 12374754 physical association X 2 P53877 P32457 two hybrid 22875988 direct interaction X 2 P53877 P40061 two hybrid 22875988 direct interaction X 2 P53877 Q03758 two hybrid 22875988 direct interaction X 2 P53877 P53935 two hybrid 22875988 direct interaction X 2 P53865 P53877 two hybrid 22875988 direct interaction X 2 P53877 P40061 two hybrid 22875988 direct interaction X 2 P53877 Q02892 affinity chromatography technology 15260980 physical association X 2 P53877 P25382 affinity chromatography technology 16429126 physical association X 2 P53877 P53927 affinity chromatography technology 16429126 physical association X 2 P53877 P25382 affinity chromatography technology 16429126 physical association X 2 P53877 P53742 affinity chromatography technology 16429126 physical association X 2 P53877 P38779 affinity chromatography technology 16429126 physical association X 2 P53877 P25382 affinity chromatography technology 17200106 physical association X 2 P53877 P40010 affinity chromatography technology 17200106 physical association X 2 P53877 P53261 affinity chromatography technology 17200106 physical association X 2 P53877 P38779 affinity chromatography technology 17200106 physical association X 2 P53877 P53927 affinity chromatography technology 17200106 physical association X 2 P53877 P53742 affinity chromatography technology 17200106 physical association X 2 P53877 Q02892 affinity chromatography technology 17200106 physical association X 2 P53877 Q06410 two hybrid 11283351 direct interaction X 2 P53877 Q06410 two hybrid 11283351 direct interaction X 2 P53877 P53927 affinity chromatography technology 17922018 physical association X 2 P53877 P40350 protein complementation assay 18467557 direct interaction X 2 P53877 P25382 affinity chromatography technology 19737519 physical association X 2 P53877 P25382 affinity chromatography technology 11805826 physical association X 2 P53877 P53927 affinity chromatography technology 11805826 physical association X 2 P53877 Q06410 affinity chromatography technology 11805837 physical association X 2 P53877 Q07896 affinity chromatography technology 22421151 physical association X 2 P53877 Q07896 biochemical 22421151 colocalization X 2 P40150 P53877 biochemical 23332755 association X 2 P43586 P53877 affinity chromatography technology 16429126 physical association X 2 P09119 P53877 affinity chromatography technology 22421151 physical association X 2 P09119 P53877 two hybrid 22421151 direct interaction X 2 P09119 P53877 two hybrid 22421151 direct interaction X 2 P30665 P53877 two hybrid 22421151 direct interaction X 2 P30665 P53877 two hybrid 22421151 direct interaction X 2 Q12019 P53877 affinity chromatography technology 15260980 physical association X 2 Q12019 P53877 affinity chromatography technology 17200106 physical association X 2 P53877 tandem affinity purification 11805826 - C 32 P53877 inferred by author 11805826 physical association C 88 P53877 tandem affinity purification 11805826 - C 15 P53877 anti tag coimmunoprecipitation 11805837 - C 13 P53877 anti tag coimmunoprecipitation 11805837 - C 7 P53877 tandem affinity purification 11805826 - C 20 P12695 P53877 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 anti tag coimmunoprecipitation 11805837 physical association X 2 P39014 P53877 two hybrid pooling approach 11283351 physical association X 2 P35191 P53877 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 P07251 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 P12709 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 P32366 two hybrid pooling approach 11283351 physical association X 2 P53877 Q08004 tandem affinity purification 11805826 physical association X 2 P53877 P02309 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 P53313 tandem affinity purification 11805826 physical association X 2 Q12522 P53877 tandem affinity purification 11805826 physical association X 2 P10659 P53877 anti tag coimmunoprecipitation 11805837 physical association X 2 Q02821 P53877 two hybrid pooling approach 11283351 physical association X 2 P09624 P53877 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 tandem affinity purification 11805826 - C 4 P53877 anti tag coimmunoprecipitation 11805837 - C 3 P53877 tandem affinity purification 11805826 - C 26 P53877 anti tag coimmunoprecipitation 11805837 - C 12 P09733 P53877 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12464 P53877 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 P02557 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 P25491 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 Q06410 two hybrid pooling approach 11283351 physical association X 2 P53877 Q06410 anti tag coimmunoprecipitation 11805837 physical association X 2 P53877 Q06410 two hybrid pooling approach 11283351 physical association X 2 P53877 P25382 tandem affinity purification 11805826 physical association X 2 P53877 P53927 tandem affinity purification 11805826 physical association X 2 P53877 inferred by author 16429126 physical association C 54 P53877 tandem affinity purification 11805826 association C 27 P53877 anti tag coimmunoprecipitation 11805837 association C 3 P53877 tandem affinity purification 19737519 association C 27 P53877 tandem affinity purification 16429126 association C 35 P53877 tandem affinity purification 16429126 association C 65 P53877 inferred by author 16429126 physical association C 28 P53877 tandem affinity purification 16429126 association C 7 P53877 tandem affinity purification 16429126 association C 15 P11484 P53877 tandem affinity purification 19536198 association X 2 Q01684 P53877 two hybrid array 14690591 physical association X 2 P39014 P53877 two hybrid fragment pooling approach 11283351 physical association X 2 Q12139 P53877 two hybrid array 14690591 physical association X 2 P36016 P53877 tandem affinity purification 19536198 association X 2 P53877 P32366 two hybrid fragment pooling approach 11283351 physical association X 2 P53877 P53877 two hybrid array 14690591 physical association X 2 P53877 P19262 two hybrid array 14690591 physical association X 2 P53877 P38803 tandem affinity purification 16554755 physical association X 2 P53877 P38803 tandem affinity purification 16554755 physical association X 2 P53877 P38803 tandem affinity purification 16554755 physical association X 2 P53877 P38803 tandem affinity purification 16554755 physical association X 2 P53877 P38803 tandem affinity purification 16554755 physical association X 2 P53877 P38803 tandem affinity purification 16554755 physical association X 2 P53877 P38803 tandem affinity purification 16554755 physical association X 2 P53877 P38803 tandem affinity purification 16554755 physical association X 2 P53877 P38996 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53877 P33416 tandem affinity purification 19536198 association X 2 Q02821 P53877 two hybrid fragment pooling approach 11283351 physical association X 2 P10591 P53877 tandem affinity purification 19536198 association X 2 P38883 P53877 two hybrid array 14690591 physical association X 2 P32854 P53877 two hybrid array 14690591 physical association X 2 P38883 P53877 tandem affinity purification 16554755 physical association X 2 P38883 P53877 tandem affinity purification 16554755 physical association X 2 P53877 anti tag coimmunoprecipitation 11805837 association C 4 P53877 pull down 14690591 association C 6 P53877 tandem affinity purification 16429126 association C 34 P53877 tandem affinity purification 16429126 association C 33 P53877 tandem affinity purification 16429126 association C 30 P53877 tandem affinity purification 11805826 association C 21 P53877 tandem affinity purification 16429126 association C 49 P53877 tandem affinity purification 15528184 association C 4 P53877 inferred by author 16429126 physical association C 91 P53877 tandem affinity purification 11805826 association C 5 P53877 pull down 14690591 association C 3 P53877 pull down 14690591 association C 3 P53877 pull down 14690591 association C 3 P53877 tandem affinity purification 15528184 association C 3 P53877 inferred by author 16554755 association C 3 P53877 tandem affinity purification 16429126 association C 37 P53877 tandem affinity purification 11805826 association C 16 P53877 tandem affinity purification 11805826 association C 33 P53877 tandem affinity purification 16429126 association C 40 P53877 inferred by author 16429126 physical association C 30 P53877 anti tag coimmunoprecipitation 11805837 association C 5 P53877 tandem affinity purification 16429126 association C 3 P53877 Q06410 two hybrid fragment pooling approach 11283351 physical association X 2 P53877 Q06410 two hybrid fragment pooling approach 11283351 physical association X 2 P53877 P49573 two hybrid array 14690591 physical association X 2 P53877 P40573 two hybrid array 14690591 physical association X 2 P53877 P40350 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53877 P38788 tandem affinity purification 19536198 association X 2 P53877 mass spectrometry studies of complexes 11805837 - C 5 P53877 mass spectrometry studies of complexes 11805837 - C 5 P53877 mass spectrometry studies of complexes 11805826 - C 106 P39014 P53877 two hybrid 11283351 - X 2 P53877 P32366 two hybrid 11283351 - X 2 Q02821 P53877 two hybrid 11283351 - X 2 P53877 mass spectrometry studies of complexes 11805837 - C 8 P53877 Q06410 two hybrid 11283351 - X 2 P53877 Q06410 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality TPK1 IPI3 16319894 0415 LC CDC6 IPI3 22421151,22421151 0004,0018 LC PHO85 IPI3 16319894 0415 LC KGD2 IPI3 14690591 0397 LC REC107 IPI3 22875988 0018 HT MCM2 IPI3 22421151,22421151 0004,0401 LC MCM4 IPI3 22421151 0018 LC VMA6 IPI3 11283351,11283351,11283351 0018,0399,0398 HT CDC3 IPI3 22875988 0018 HT ORC2 IPI3 22421151 0018 LC PEP12 IPI3 14690591 0397 LC COY1 IPI3 22875988 0018 HT LHS1 IPI3 22875988 0018 HT KSP1 IPI3 16319894 0415 LC RIX1 IPI3 23142978,14690591,14690591,14690591 0401,0096,0018,0397 LC SKN7 IPI3 22875988 0018 HT NAB3 IPI3 18467557,18467557 0111,0090 HT MET30 IPI3 11283351,11283351,11283351 0018,0399,0398 HT SNF7 IPI3 22875988 0018 HT TSC11 IPI3 22875988 0018 HT SSB2 IPI3 23332755 0401 LC ALG5 IPI3 18467557,18467557 0111,0090 HT MET28 IPI3 14690591 0397 LC TAH11 IPI3 22421151,22421151 0004,0018 LC CTR1 IPI3 14690591 0397 LC ATG1 IPI3 22875988,16319894 0018,0415 HT,LC SPC105 IPI3 22875988 0018 HT SDA1 IPI3 23142978 0401 LC CNM67 IPI3 22875988 0018 HT IPI3 IPI3 14690591 0397 LC IPI3 NST1 22875988 0018 HT IPI3 ORC3 22421151,22421151 0004,0401 LC IPI3 DID2 22875988 0018 HT IPI3 SPR6 14690591,14690591 0018,0397 LC IPI3 SRP1 11283351,11283351,11283351 0018,0399,0398 HT IPI3 BUL2 22875988 0018 HT IPI3 YAP6 22875988 0018 HT IPI3 SHE9 22875988 0018 HT IPI3 ATG17 11283351,11283351,11283351 0018,0399,0398 HT IPI3 NOC3 22421151,22421151 0004,0401 LC IPI3 Q12139 14690591,14690591 0018,0397 LC IPI3 RLF2 22875988 0018 HT HHF1|HHF2 IPI3 11805837,11805837 0004,0007 HT TUB2 IPI3 11805837 0007 HT ATP1 IPI3 11805837 0007 HT CDC6 IPI3 22421151,22421151 0004,0018 LC LPD1 IPI3 11805837 0007 HT TUB1 IPI3 11805837 0007 HT SSA1 IPI3 19536198 0676 HT SAM1 IPI3 11805837 0007 HT SSB1 IPI3 19536198 0676 HT LAT1 IPI3 11805837 0007 HT PGI1 IPI3 11805837 0007 HT RPL3 IPI3 17200106 0004 HT MCM3 IPI3 22421151 0004 LC RSA4 IPI3 16429126,11805826,11805826,19737519,17200106,11805826,16429126 0004,0676,0004,0004,0004,0007,0676 HT,LC YDJ1 IPI3 11805837 0007 HT SPB4 IPI3 21825077 0004 LC MCM2 IPI3 22421151,22421151 0004,0401 LC MRT4 IPI3 17200106,19797079 0004,0004 HT,LC HSP78 IPI3 19536198 0676 HT MDJ1 IPI3 11805837 0007 HT LHS1 IPI3 19536198 0676 HT CIC1 IPI3 17200106,16429126,16429126 0004,0676,0004 HT SSZ1 IPI3 19536198 0676 HT IPI1 IPI3 16554755,16429126,16554755,17200106,14759368,16429126,16554755 0676,0004,0363,0004,0004,0676,0004 HT RIX1 IPI3 11805837,15260980,23142978,16554755,20542003,21777812,16429126,15528184,20100801,12374754,15528184,19737519,17200106,19737519,16429126,11805837,16554755 0004,0004,0401,0676,0004,0004,0004,0676,0004,0004,0004,0676,0004,0004,0676,0007,0004 HT,LC NUG1 IPI3 12374754,17200106 0004,0004 LC,HT SSB2 IPI3 23332755 0401 LC RLP7 IPI3 23945946,17200106 0004,0004 LC,HT LOC1 IPI3 16429126,16429126 0676,0004 HT ALB1 IPI3 23045392,17803941 0004,0004 LC TAH11 IPI3 22421151,22421151 0004,0018 LC NOP7 IPI3 17200106 0004 HT SDA1 IPI3 12374754,23142978,16429126,11805826,15260980,11805826,17200106,11805826,16429126 0004,0401,0676,0004,0004,0676,0004,0007,0004 LC,HT NOG2 IPI3 17200106,16429126,16429126 0004,0676,0004 HT IPI3 NOP15 16429126,17922018,11805826,11805826,17200106,11805826,16429126 0676,0004,0676,0004,0004,0007,0004 HT,LC IPI3 ORC1 22421151 0004 LC IPI3 ORC3 22421151,22421151 0004,0401 LC IPI3 HHT1|HHT2 22199229 0004 HT IPI3 NOG1 15260980,17200106 0004,0004 LC,HT IPI3 ARX1 17803941,16429126,23045392,17200106,16429126,16429126 0004,0676,0004,0004,0004,0363 LC,HT IPI3 MMS22 26849847 0004 LC IPI3 ATG17 11805837,11805837 0004,0007 HT IPI3 NOC3 22421151,22421151 0004,0401 LC IPI3 BUD20 16429126,11805826,23045392,11805826,23045392,11805826,16429126 0676,0676,0004,0004,0676,0007,0004 HT,LC IPI3 MDN1 15260980,17200106 0004,0004 LC,HT IPI3 DBP10 17200106 0004 HT IPI3 RVB2 11805837 0007 HT IPI3 TIF6 16429126,11805826,11805826,17200106,11805826,16429126 0676,0676,0004,0004,0007,0004 HT IPI3 Q9ZZX7 11805837 0007 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53877 P53104 IPI3 ATG1 0.183 16319894 P53877 P53742 IPI3 NOG2 0.126 16429126 P53877 P24279 IPI3 MCM3 0.126 22421151 Q12139 P53877 Q12139 IPI3 0.126 14690591 Q12464 P53877 RVB2 IPI3 0.126 11805837 P53877 P25491 IPI3 YDJ1 0.126 11805837 P53877 P17157 IPI3 PHO85 0.183 16319894 P53877 P09733 IPI3 TUB1 0.126 11805837 P53877 P10659 IPI3 SAM1 0.126 11805837 P53877 P02557 IPI3 TUB2 0.126 11805837 P53877 P12695 IPI3 LAT1 0.126 11805837 P53877 P06244 IPI3 TPK1 0.183 16319894 P53877 P07251 IPI3 ATP1 0.126 11805837 Q06410 P53877 ATG17 IPI3 0.554 11805837,11283351 P53877 P47019 IPI3 ALB1 0.309 23045392,17803941 P53877 P38803 IPI3 IPI1 0.61 16554755,14690591,16429126 P53877 P38883 IPI3 RIX1 0.941 14690591,16429126,20542003,16554755,11805837,20100801,21777812,15528184,23142978,19737519 Q03862 P53877 ARX1 IPI3 0.472 17803941,16429126,23045392 P53877 P29469 IPI3 MCM2 0.298 22421151 P53877 P25808 IPI3 SPB4 0.126 21825077 P53877 P30665 IPI3 MCM4 0.332 22421151 P53877 P38691 IPI3 KSP1 0.183 16319894 P53877 P38779 IPI3 CIC1 0.126 16429126 P53877 P38996 IPI3 NAB3 0.126 18467557 P53877 P32833 IPI3 ORC2 0.332 22421151 P53877 P32854 IPI3 PEP12 0.126 14690591 P53877 P33201 IPI3 MRT4 0.126 19797079 P53877 P40061 IPI3 TSC11 0.183 22875988 P53877 P40150 IPI3 SSB2 0.126 23332755 P53877 P40573 IPI3 MET28 0.126 14690591 P53877 P43586 IPI3 LOC1 0.126 16429126 P53877 P40350 IPI3 ALG5 0.126 18467557 Q12522 P53877 TIF6 IPI3 0.286 11805826,16429126 P53877 P49573 IPI3 CTR1 0.126 14690591 P53877 P19262 IPI3 KGD2 0.126 14690591 Q01684 P53877 SPR6 IPI3 0.126 14690591 Q07468 P53877 VAM6 IPI3 0.126 25026036 P53877 P02309 IPI3 HHF2 0.236 11805837 P53877 P09119 IPI3 CDC6 0.416 22421151 P53877 P09624 IPI3 LPD1 0.126 11805837 P53877 P10591 IPI3 SSA1 0.126 19536198 P53877 P11484 IPI3 SSB1 0.126 19536198 P53877 P11792 IPI3 SCH9 0.126 14690591 P53877 P12709 IPI3 PGI1 0.126 11805837 P53877 P19158 IPI3 IRA2 0.126 14690591 P53877 P25382 IPI3 RSA4 0.436 11805826,19737519,16429126 P53877 P32366 IPI3 VMA6 0.21 11283351 P53877 P33416 IPI3 HSP78 0.126 19536198 P53877 P35191 IPI3 MDJ1 0.126 11805837 P53877 P36016 IPI3 LHS1 0.126 19536198 P53877 P38788 IPI3 SSZ1 0.126 19536198 P53877 P39014 IPI3 MET30 0.21 11283351 P53877 P47112 IPI3 TAH11 0.416 22421151 P53877 P52593 IPI3 NUP188 0.126 14690591 P53877 P53313 IPI3 SDA1 0.416 11805826,23142978,16429126 P53877 P53877 IPI3 IPI3 0.155 14690591 P53927 P53877 NOP15 IPI3 0.416 11805826,17922018,16429126 P54784 P53877 ORC1 IPI3 0.126 22421151 Q02197 P53877 MAK10 IPI3 0.126 14690591 Q02821 P53877 SRP1 IPI3 0.21 11283351 Q06554 P53877 IRC20 IPI3 0.126 14690591 Q07896 P53877 NOC3 IPI3 0.196 22421151 Q08004 P53877 BUD20 IPI3 0.554 11805826,23045392,16429126 Q9ZZX7 P53877 Q9ZZX7 IPI3 0.126 11805837 Q07807 P53877 PUF3 IPI3 0.126 P54790 P53877 ORC3 IPI3 0.298 22421151