PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RCK1 UBP10 16319894,21460040 biogrid,i2d exp GCD6 UBP10 i2d exp FUS3 UBP10 16319894 biogrid,i2d exp RPL18B UBP10 22902402 biogrid exp HTB1 UBP10 i2d exp UBP10 FPR4 22902402 biogrid exp CAJ1 UBP10 19536198 intact exp NCL1 UBP10 22902402 biogrid exp SPT16 UBP10 22902402 biogrid exp ERJ5 UBP10 19536198 intact exp UBP10 AIR2 16429126 intact exp GEA1 UBP10 16554755 biogrid,i2d,mint,intact exp TOS3 UBP10 16319894 biogrid,i2d exp MIR1 UBP10 22902402 biogrid exp UBP10 MRD1 22902402 biogrid exp MAK11 UBP10 22902402 biogrid exp UBP10 ROY1 i2d exp VMA13 UBP10 22902402 biogrid exp SEC53 UBP10 22902402 biogrid exp URA5 UBP10 22902402 biogrid exp SPA2 UBP10 i2d exp PDS1 UBP10 22072716 biogrid exp SEC63 UBP10 19536198 intact exp HSC82 UBP10 19536198,15766533,16554755 biogrid,i2d,mint,intact exp UBP10 HAS1 22902402 biogrid exp ASN2 UBP10 22902402 biogrid exp SSB1 UBP10 19536198 i2d,intact exp UBP10 UTP13 22902402 biogrid exp SEC4 UBP10 22902402 biogrid exp SSC1 UBP10 19536198 intact exp GLY1 UBP10 22902402 biogrid exp RNR4 UBP10 22902402 biogrid exp UBP10 NOP58 22902402 biogrid exp IRA1 UBP10 i2d exp LYS20 UBP10 22902402 biogrid exp UBP10 HCR1 i2d exp ACS2 UBP10 22902402 biogrid exp UBP10 Putative serine/threonine-protein kinase YPL150W 16319894 biogrid,i2d exp NSR1 UBP10 22902402 biogrid exp RAD26 UBP10 i2d exp UBP10 SEC13 22902402 biogrid exp UBP10 UBC7 14690591 intact exp SUP45 UBP10 22902402 biogrid exp RPL7A UBP10 22902402 biogrid exp SSB2 UBP10 19536198 intact exp UBP10 MAK21 22902402 biogrid exp RPS1A UBP10 22902402 biogrid exp PYC2 UBP10 22902402 biogrid exp NUG1 UBP10 22902402 biogrid exp DPH5 UBP10 22902402 biogrid exp UBP10 NOG1 22902402 biogrid exp CHZ1 UBP10 i2d exp GAR1 UBP10 18467557 biogrid,i2d,mint,intact exp CAM1 UBP10 22902402 biogrid exp PIC2 UBP10 i2d exp UBP10 HRP1 22902402 biogrid exp UBP10 MDN1 22902402 biogrid exp HTB2 UBP10 22902402 biogrid exp KSS1 UBP10 16319894 biogrid,i2d exp YCK2 UBP10 16319894 biogrid,i2d exp UTP7 UBP10 22902402 biogrid exp NOC2 UBP10 22902402,18467557 biogrid,i2d,mint,intact exp DBP2 UBP10 22902402,18467557 biogrid,i2d,mint,intact exp BMH2 UBP10 22902402 biogrid exp PRP43 UBP10 22902402 biogrid exp UBP10 FMP42 i2d exp UBP10 UTP4 22902402 biogrid exp UBP10 NOP56 22902402 biogrid,i2d exp URA7 UBP10 22902402 biogrid exp NOP19 UBP10 16554755 biogrid,i2d,mint,intact exp CKA2 UBP10 16554755 biogrid,i2d,mint,intact exp NOP1 UBP10 22902402 biogrid exp SSA3 UBP10 19536198 intact exp PRP40 UBP10 16606443 biogrid,mint,intact exp UBP10 KRE33 22902402 biogrid exp SSA1 UBP10 19536198 i2d,intact exp HEK2 UBP10 18805955 biogrid exp UBP10 NOP12 22902402 biogrid exp UBP10 NAN1 22902402 biogrid exp FMP48 UBP10 16319894 biogrid,i2d exp UBP10 UFD2 i2d exp SWE1 UBP10 16319894 biogrid,i2d exp CNS1 UBP10 i2d exp GIP2 UBP10 i2d exp UBP10 BFR2 22902402 biogrid exp KIN2 UBP10 16319894 biogrid,i2d exp RPA14 UBP10 i2d exp KSP1 UBP10 16319894 biogrid,i2d exp RPA190 UBP10 22902402 biogrid exp GCD11 UBP10 22902402 biogrid,i2d exp PEX1 UBP10 i2d exp HSP78 UBP10 19536198 intact exp UBP10 Uncharacterized protein YLR271W i2d exp UBP10 DIP2 18467557 biogrid,i2d,mint,intact exp UBP10 ETT1 22902402 biogrid exp HUL5 UBP10 i2d exp UBP10 AAT1 i2d exp MKT1 UBP10 16554755 biogrid,i2d,mint,intact exp UTP10 UBP10 22902402 biogrid exp UBP10 BRX1 22902402 biogrid,i2d exp RNR2 UBP10 22902402 biogrid exp UBP10 DBP9 22902402 biogrid exp SSE2 UBP10 19536198 i2d,intact exp SSZ1 UBP10 19536198 intact exp CWH41 UBP10 i2d exp SSE1 UBP10 19536198 i2d,intact exp SNF1 UBP10 16319894 biogrid,i2d exp SLI15 UBP10 i2d exp UBP10 PUF3 23409723 biogrid exp CMK1 UBP10 16319894 biogrid,i2d exp UBP10 SKM1 16319894 biogrid,i2d exp UBP10 Glucose-6-phosphate 1-epimerase 22902402 biogrid exp PES4 UBP10 i2d exp NOP7 UBP10 22902402 biogrid exp ECM10 UBP10 19536198 intact exp SBP1 UBP10 23222640 biogrid exp UBP10 SKY1 16319894 biogrid,i2d exp PWP2 UBP10 22902402 biogrid exp IME2 UBP10 16319894 biogrid,i2d exp RPF2 UBP10 i2d exp SSA2 UBP10 16429126,19536198 i2d,intact exp PNC1 UBP10 i2d exp XRN1 UBP10 i2d exp UBP10 BCK1 16319894 biogrid,i2d exp UBP10 PAR32 i2d exp PRK1 UBP10 16319894 biogrid,i2d exp ILV2 UBP10 i2d exp UBP10 YRA1 22902402 biogrid exp KIN3 UBP10 i2d exp UBP10 SUB2 22902402 biogrid exp UBP10 RRP9 18467557 biogrid,i2d,mint,intact exp SPS1 UBP10 21460040 biogrid exp RPL13B UBP10 22902402 biogrid exp HSP26 UBP10 19536198 intact exp ATG1 UBP10 16319894 biogrid,i2d exp SNU114 UBP10 18467557 biogrid,i2d,mint,intact exp GCN1 UBP10 22902402 biogrid exp SRS2 UBP10 15964827 biogrid exp CBF5 UBP10 22902402,16554755 biogrid,i2d,mint,intact exp TAH11 UBP10 i2d exp MCK1 UBP10 i2d exp UBP10 NUP116 i2d exp UBP10 RRP5 22902402 biogrid exp SBA1 UBP10 21777812 biogrid exp HCA4 UBP10 22902402 biogrid exp UBP10 RPL6A 22902402 biogrid exp URA2 UBP10 22902402 biogrid exp BCH2 UBP10 i2d exp GCN20 UBP10 16554755 biogrid,i2d,mint,intact exp ADE3 UBP10 22902402 biogrid exp UBP10 MPS1 16319894 biogrid,i2d exp PHO85 UBP10 16319894 biogrid,i2d exp TKL1 UBP10 22902402 biogrid exp CDC28 UBP10 16319894 biogrid exp NOP4 UBP10 22902402 biogrid exp SOF1 UBP10 18467557 biogrid,i2d,mint,intact exp CDC48 UBP10 22902402 biogrid exp SIS1 UBP10 22902402,19536198 biogrid,intact exp RAD53 UBP10 16319894 biogrid,i2d exp LOC1 UBP10 18467557 biogrid,i2d,mint,intact exp DHR2 UBP10 22902402,22615397,18467557,16554755 biogrid,i2d,mint,intact exp IMD4 UBP10 22902402 biogrid exp RSA4 UBP10 16554755 biogrid,i2d,mint,intact exp UBP10 NPL3 22902402 biogrid exp UBP10 Putative ATP-dependent RNA helicase YLR419W i2d exp POL5 UBP10 22902402 biogrid exp GND1 UBP10 22902402 biogrid exp FPR3 UBP10 22902402 biogrid exp SWP82 UBP10 22902402 biogrid exp TPK1 UBP10 16319894 biogrid,i2d exp PTK2 UBP10 16319894 biogrid,i2d exp HSP82 UBP10 19536198,15766533 biogrid,i2d,intact exp DED1 UBP10 16429126 intact exp PWP1 UBP10 22902402 biogrid exp PKP2 UBP10 16319894 biogrid,i2d exp MRPS5 UBP10 11805826,16429126 biogrid,mint,intact,dip exp DRS1 UBP10 22902402 biogrid exp YCK1 UBP10 16319894 biogrid,i2d exp RPC40 UBP10 i2d exp POL30 UBP10 22829782 biogrid exp UBP10 PST2 i2d exp ATP3 UBP10 i2d exp RPL31A UBP10 22902402 biogrid exp BEM2 UBP10 16429126 intact exp RLP7 UBP10 18467557, 23023127 biogrid,i2d,mint,intact exp, pred UBP10 UBP10 22902402,18467557, 23023127 biogrid,i2d,mint,intact exp, pred UBP10 RPA49 16554755, 23023127 biogrid,i2d,mint,intact exp, pred SIR4 UBP10 10490600,16554755, 23023127 biogrid,i2d,mint,intact exp, pred STM1 UBP10 16554755, 23023127 biogrid,i2d,mint,intact exp, pred UTP22 UBP10 22902402,16554755, 23023127 biogrid,i2d,mint,intact exp, pred UBP10 NOP6 18467557, 23023127 biogrid,i2d,mint,intact exp, pred ESS1 UBP10 16606443, 23023127 biogrid,mint,intact exp, pred SET2 UBP10 16606443, 23023127 biogrid,mint,intact exp, pred SSN3 UBP10 16319894, 23023127 biogrid,i2d exp, pred CIC1 UBP10 18467557, 23023127 biogrid,i2d,mint,intact exp, pred RRP7 UBP10 16554755, 23023127 biogrid,i2d,mint,intact exp, pred WWM1 UBP10 16606443, 23023127 biogrid,mint,intact exp, pred PRB1 UBP10 16554755, 23023127 biogrid,i2d,mint,intact exp, pred UBP10 UBP16 23023127 pred UBP6 UBP10 23023127 pred UBP5 UBP10 23023127 pred DOA4 UBP10 23023127 pred UBP7 UBP10 23023127 pred SIR2 UBP10 23023127 pred UBP10 UBP3 23023127 pred UBP8 UBP10 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P16892 P53874 enzymatic study 16319894 direct interaction X 2 P43554 P53874 affinity chromatography technology 22902402 physical association X 2 P06782 P53874 enzymatic study 16319894 direct interaction X 2 P23292 P53874 enzymatic study 16319894 direct interaction X 2 P05737 P53874 affinity chromatography technology 22902402 physical association X 2 Q06631 P53874 affinity chromatography technology 22902402 physical association X 2 P40693 P53874 protein complementation assay 18467557 direct interaction X 2 P38691 P53874 enzymatic study 16319894 direct interaction X 2 Q05022 P53874 affinity chromatography technology 22902402 physical association X 2 P53233 P53874 enzymatic study 16319894 direct interaction X 2 P40212 P53874 affinity chromatography technology 22902402 physical association X 2 P32327 P53874 affinity chromatography technology 22902402 physical association X 2 P24783 P53874 affinity chromatography technology 22902402 physical association X 2 P20484 P53874 affinity chromatography technology 22902402 physical association X 2 P24783 P53874 protein complementation assay 18467557 direct interaction X 2 P53874 Q12460 affinity chromatography technology 22902402 physical association X 2 P53874 W4YHN9 enzymatic study 22072716 direct interaction X 2 P53874 P40316 enzymatic study 22072716 direct interaction X 2 P53874 P49090 affinity chromatography technology 22902402 physical association X 2 P53874 Q06218 affinity chromatography technology 22902402 physical association X 2 P53874 Q06205 affinity chromatography technology 22902402 physical association X 2 P53874 P48570 affinity chromatography technology 22902402 physical association X 2 P53874 P38205 affinity chromatography technology 22902402 physical association X 2 P53874 P39744 affinity chromatography technology 22902402 physical association X 2 P53874 Q02892 affinity chromatography technology 22902402 physical association X 2 P53874 Q12460 affinity chromatography technology 22902402 physical association X 2 P53874 P0C2H8 affinity chromatography technology 22902402 physical association X 2 P53874 P07560 affinity chromatography technology 22902402 physical association X 2 P53874 P25294 affinity chromatography technology 22902402 physical association X 2 P53874 Q07478 affinity chromatography technology 22902402 physical association X 2 P53874 P53874 affinity chromatography technology 22902402 physical association X 2 P53874 P07259 affinity chromatography technology 22902402 physical association X 2 P53874 P13298 affinity chromatography technology 22902402 physical association X 2 P53874 P42945 affinity chromatography technology 22902402 physical association X 2 P53874 Q06679 affinity chromatography technology 22902402 physical association X 2 P53874 P41807 affinity chromatography technology 22902402 physical association X 2 P53874 Q03161 affinity chromatography technology 22902402 physical association X 2 P53874 Q08235 affinity chromatography technology 22902402 physical association X 2 P53874 Q12159 affinity chromatography technology 22902402 physical association X 2 P53874 P25368 affinity chromatography technology 16554755 physical association X 2 P53874 P40850 affinity chromatography technology 16554755 physical association X 2 P53874 P53104 enzymatic study 16319894 direct interaction X 2 P53874 P14681 enzymatic study 16319894 direct interaction X 2 P53874 P47116 enzymatic study 16319894 direct interaction X 2 P53874 Q12469 enzymatic study 16319894 direct interaction X 2 P53874 Q03656 enzymatic study 16319894 direct interaction X 2 P53874 P23291 enzymatic study 16319894 direct interaction X 2 P53874 Q07623 protein complementation assay 18467557 direct interaction X 2 P53874 P38779 protein complementation assay 18467557 direct interaction X 2 P53874 P28007 protein complementation assay 18467557 direct interaction X 2 P53874 Q06506 protein complementation assay 18467557 direct interaction X 2 P53874 P53874 protein complementation assay 18467557 direct interaction X 2 P53874 P39744 protein complementation assay 18467557 direct interaction X 2 P53874 P17157 enzymatic study 16319894 direct interaction X 2 P53874 P08458 pull down 21460040 direct interaction X 2 P53874 P28707 pull down 21777812 direct interaction X 2 P53874 P28707 two hybrid 21777812 direct interaction X 2 P53874 P43582 unspecified method 16606443 direct interaction X 2 P53874 P33203 unspecified method 16606443 direct interaction X 2 P40055 P53874 affinity chromatography technology 22902402 physical association X 2 P47102 P53874 affinity chromatography technology 16554755 physical association X 2 P15873 P53874 affinity chromatography technology 22829782 physical association X 2 P15873 P53874 affinity chromatography technology 22829782 physical association X 2 P32481 P53874 affinity chromatography technology 22902402 physical association X 2 Q12176 P53874 affinity chromatography technology 22902402 physical association X 2 P25635 P53874 affinity chromatography technology 22902402 physical association X 2 P25635 P53874 affinity chromatography technology 22902402 physical association X 2 P25635 P53874 affinity chromatography technology 22902402 physical association X 2 P19454 P53874 affinity chromatography technology 16554755 physical association X 2 P13186 P53874 enzymatic study 16319894 direct interaction X 2 P32558 P53874 affinity chromatography technology 22902402 physical association X 2 P09232 P53874 affinity chromatography technology 16554755 physical association X 2 Q12152 P53874 enzymatic study 16319894 direct interaction X 2 P38911 P53874 affinity chromatography technology 22902402 physical association X 2 P32892 P53874 affinity chromatography technology 22902402 physical association X 2 P07245 P53874 affinity chromatography technology 22902402 physical association X 2 P43586 P53874 protein complementation assay 18467557 direct interaction X 2 P33759 P53874 affinity chromatography technology 16429126 physical association X 2 P33759 P53874 affinity chromatography technology 11805826 physical association X 2 P39015 P53874 affinity chromatography technology 16554755 physical association X 2 P50094 P53874 affinity chromatography technology 22902402 physical association X 2 P38622 P53874 enzymatic study 16319894 direct interaction X 2 P38622 P53874 pull down 21460040 direct interaction X 2 P53131 P53874 affinity chromatography technology 22902402 physical association X 2 Q12019 P53874 affinity chromatography technology 22902402 physical association X 2 P22216 P53874 enzymatic study 16319894 direct interaction X 2 P53254 P53874 two hybrid 22902402 direct interaction X 2 P53254 P53874 affinity chromatography technology 22902402 physical association X 2 P53254 P53874 affinity chromatography technology 16554755 physical association X 2 P21304 P53874 affinity chromatography technology 22902402 physical association X 2 P52910 P53874 affinity chromatography technology 22902402 physical association X 2 P02294 P53874 affinity chromatography technology 22902402 physical association X 2 P15108 P53874 affinity chromatography technology 16554755 physical association X 2 Q04491 P53874 affinity chromatography technology 22902402 physical association X 2 P11978 P53874 two hybrid 10490600 direct interaction X 2 P11978 P53874 affinity chromatography technology 16554755 physical association X 2 Q12499 P53874 affinity chromatography technology 22902402 physical association X 2 Q12499 P53874 affinity chromatography technology 22902402 physical association X 2 Q02931 P53874 affinity chromatography technology 22902402 physical association X 2 P40494 P53874 enzymatic study 16319894 direct interaction X 2 P02829 P53874 affinity chromatography technology 15766533 physical association X 2 P39985 P53874 affinity chromatography technology 22902402 physical association X 2 Q01560 P53874 affinity chromatography technology 22902402 physical association X 2 P53874 P33322 affinity chromatography technology 22902402 physical association X 2 P53874 P10964 enzymatic study 22902402 direct interaction X 2 P53874 P34730 affinity chromatography technology 22902402 physical association X 2 P53874 P33322 affinity chromatography technology 22902402 physical association X 2 P53874 P25694 affinity chromatography technology 22902402 physical association X 2 P53874 P20448 affinity chromatography technology 22902402 physical association X 2 P53874 P32469 affinity chromatography technology 22902402 physical association X 2 P53874 P37303 affinity chromatography technology 22902402 physical association X 2 P53874 P53914 affinity chromatography technology 22902402 physical association X 2 P53874 P23641 affinity chromatography technology 22902402 physical association X 2 P53874 Q06106 affinity chromatography technology 22902402 physical association X 2 P53874 P15646 affinity chromatography technology 22902402 physical association X 2 P53874 Q08208 affinity chromatography technology 22902402 physical association X 2 P53874 P53261 affinity chromatography technology 22902402 physical association X 2 P53874 P27476 affinity chromatography technology 22902402 physical association X 2 P53874 P40010 affinity chromatography technology 22902402 physical association X 2 P53874 P09938 affinity chromatography technology 22902402 physical association X 2 P53874 P10964 affinity chromatography technology 22902402 physical association X 2 P53874 Q02326 affinity chromatography technology 22902402 physical association X 2 P53874 P12385 affinity chromatography technology 22902402 physical association X 2 P53874 P23254 affinity chromatography technology 22902402 physical association X 2 P53874 P25382 affinity chromatography technology 16554755 physical association X 2 P53874 P33322 affinity chromatography technology 16554755 physical association X 2 P53874 P32581 enzymatic study 16319894 direct interaction X 2 P53874 P39073 enzymatic study 16319894 direct interaction X 2 P53874 P32944 enzymatic study 16319894 direct interaction X 2 P53874 P43637 enzymatic study 16319894 direct interaction X 2 P53874 P36048 protein complementation assay 18467557 direct interaction X 2 P53874 P33750 protein complementation assay 18467557 direct interaction X 2 P53874 P00546 enzymatic study 16319894 direct interaction X 2 P12954 P53874 two hybrid 15964827 direct interaction X 2 P49723 P53874 affinity chromatography technology 22902402 physical association X 2 P38720 P53874 affinity chromatography technology 22902402 physical association X 2 P54199 P53874 enzymatic study 16319894 direct interaction X 2 Q01080 P53874 affinity chromatography technology 16554755 physical association X 2 Q99383 P53874 affinity chromatography technology 22902402 physical association X 2 P37838 P53874 affinity chromatography technology 22902402 physical association X 2 Q01389 P53874 enzymatic study 16319894 direct interaction X 2 P36009 P53874 two hybrid 22902402 direct interaction X 2 P36009 P53874 affinity chromatography technology 22902402 physical association X 2 Q05946 P53874 affinity chromatography technology 22902402 physical association X 2 P36009 P53874 affinity chromatography technology 16554755 physical association X 2 P36009 P53874 affinity chromatography technology 17200106 physical association X 2 P36009 P53874 protein complementation assay 18467557 direct interaction X 2 P36009 P53874 protein complementation assay 22615397 direct interaction X 2 P46995 P53874 unspecified method 16606443 direct interaction X 2 P07283 P53874 affinity chromatography technology 22902402 physical association X 2 Q12220 P53874 protein complementation assay 18467557 direct interaction X 2 P33442 P53874 affinity chromatography technology 22902402 physical association X 2 P29547 P53874 affinity chromatography technology 22902402 physical association X 2 P28274 P53874 affinity chromatography technology 22902402 physical association X 2 P33892 P53874 affinity chromatography technology 22902402 physical association X 2 P0CX49 P53874 affinity chromatography technology 22902402 physical association X 2 Q08421 P53874 affinity chromatography technology 22902402 physical association X 2 P43535 P53874 affinity chromatography technology 16554755 physical association X 2 P06244 P53874 enzymatic study 16319894 direct interaction X 2 P27466 P53874 enzymatic study 16319894 direct interaction X 2 Q03532 P53874 affinity chromatography technology 22902402 physical association X 2 P53170 P53874 enzymatic study 16319894 direct interaction X 2 P22696 P53874 unspecified method 16606443 direct interaction X 2 P53317 P53874 affinity chromatography technology 16554755 physical association X 2 P53874 inferred by author 16429126 physical association C 24 P53874 inferred by author 16429126 physical association C 33 P53874 inferred by author 16554755 association C 7 P53874 tandem affinity purification 11805826 association C 35 P10592 P53874 tandem affinity purification 16429126 physical association X 2 P10592 P53874 tandem affinity purification 19536198 association X 2 P40693 P53874 dihydrofolate reductase reconstruction 18467557 physical association X 2 P24783 P53874 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 P40850 tandem affinity purification 16554755 physical association X 2 P53874 P25368 tandem affinity purification 16554755 physical association X 2 P53874 P25368 tandem affinity purification 16554755 physical association X 2 P53874 P43582 protein array 16606443 direct interaction X 2 P53874 P33203 protein array 16606443 direct interaction X 2 P53874 P28007 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 P38779 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 P39744 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 Q06506 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 Q07623 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 P53874 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 P25294 tandem affinity purification 19536198 association X 2 P53874 P43613 tandem affinity purification 19536198 association X 2 P53874 P09435 tandem affinity purification 19536198 association X 2 P53874 P39987 tandem affinity purification 19536198 association X 2 P53874 P33416 tandem affinity purification 19536198 association X 2 P53874 P15992 tandem affinity purification 19536198 association X 2 P53874 P38788 tandem affinity purification 19536198 association X 2 P32590 P53874 tandem affinity purification 19536198 association X 2 P47102 P53874 tandem affinity purification 16554755 physical association X 2 P19454 P53874 tandem affinity purification 16554755 physical association X 2 P19454 P53874 tandem affinity purification 16554755 physical association X 2 P19454 P53874 tandem affinity purification 16554755 physical association X 2 P19454 P53874 tandem affinity purification 16554755 physical association X 2 P09232 P53874 tandem affinity purification 16554755 physical association X 2 P43586 P53874 dihydrofolate reductase reconstruction 18467557 physical association X 2 P39015 P53874 tandem affinity purification 16554755 physical association X 2 P10591 P53874 tandem affinity purification 19536198 association X 2 P53874 inferred by author 16429126 physical association C 31 P53874 tandem affinity purification 16429126 association C 41 P32589 P53874 tandem affinity purification 19536198 association X 2 P53254 P53874 tandem affinity purification 16554755 physical association X 2 P53254 P53874 tandem affinity purification 16554755 physical association X 2 P53254 P53874 tandem affinity purification 16554755 physical association X 2 P53254 P53874 tandem affinity purification 16554755 physical association X 2 P53254 P53874 tandem affinity purification 16554755 physical association X 2 P11484 P53874 tandem affinity purification 19536198 association X 2 P39101 P53874 tandem affinity purification 19536198 association X 2 P15108 P53874 affinity chromatography technology 15766533 physical association X 2 P15108 P53874 tandem affinity purification 16554755 physical association X 2 P15108 P53874 tandem affinity purification 16554755 physical association X 2 P15108 P53874 tandem affinity purification 19536198 association X 2 P14906 P53874 tandem affinity purification 19536198 association X 2 P11978 P53874 tandem affinity purification 16554755 physical association X 2 P11978 P53874 tandem affinity purification 16554755 physical association X 2 P11978 P53874 tandem affinity purification 16554755 physical association X 2 Q02159 P53874 two hybrid array 14690591 physical association X 2 P02829 P53874 affinity chromatography technology 15766533 physical association X 2 P02829 P53874 tandem affinity purification 19536198 association X 2 P53874 P25382 tandem affinity purification 16554755 physical association X 2 P53874 P25382 tandem affinity purification 16554755 physical association X 2 P53874 P33322 tandem affinity purification 16554755 physical association X 2 P53874 P33322 tandem affinity purification 16554755 physical association X 2 P53874 P33750 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 P36048 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53874 P0CS90 tandem affinity purification 19536198 association X 2 Q01080 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 tandem affinity purification 16554755 physical association X 2 P36009 P53874 dihydrofolate reductase reconstruction 18467557 physical association X 2 P46995 P53874 protein array 16606443 direct interaction X 2 Q12220 P53874 dihydrofolate reductase reconstruction 18467557 physical association X 2 P40150 P53874 tandem affinity purification 19536198 association X 2 P43535 P53874 tandem affinity purification 16554755 physical association X 2 P43535 P53874 tandem affinity purification 16554755 physical association X 2 P22696 P53874 protein array 16606443 direct interaction X 2 P53317 P53874 tandem affinity purification 16554755 physical association X 2 P53317 P53874 tandem affinity purification 16554755 physical association X 2 P53874 mass spectrometry studies of complexes 11805826 - C 43

PPI - HINT Gene A Gene B PMID Method Quality CDC28 UBP10 16319894 0415 LC HTB1 UBP10 26149687,15721261 0415,0045 LC TPK1 UBP10 16319894 0415 LC SNF1 UBP10 16319894 0415 LC RPA190 UBP10 22902402,22902402 0415,0004 LC SIR4 UBP10 26149687,10490600 0018,0018 LC SRS2 UBP10 15964827 0018 LC KIN2 UBP10 16319894 0415 LC KSS1 UBP10 16319894 0415 LC FUS3 UBP10 16319894 0415 LC PHO85 UBP10 16319894 0415 LC RAD53 UBP10 16319894 0415 LC ESS1 UBP10 16606443 0089 HT YCK1 UBP10 16319894 0415 LC YCK2 UBP10 16319894 0415 LC DBP2 UBP10 18467557,18467557 0090,0111 HT CMK1 UBP10 16319894 0415 LC GAR1 UBP10 18467557,18467557 0111,0090 HT SBA1 UBP10 21777812,21777812 0018,0096 LC IME2 UBP10 16319894 0415 LC SWE1 UBP10 16319894 0415 LC PRP40 UBP10 16606443 0089 HT SOF1 UBP10 18467557,18467557 0111,0090 HT DHR2 UBP10 22902402,18467557,18467557,22902402,22615397,26149687 0018,0111,0090,0004,0090,0018 LC,HT SNU114 UBP10 18467557,18467557 0111,0090 HT RCK1 UBP10 16319894 0415 LC KSP1 UBP10 16319894 0415 LC CIC1 UBP10 18467557,18467557 0111,0090 HT SSN3 UBP10 16319894 0415 LC NOC2 UBP10 18467557,18467557 0090,0111 HT PDS1 UBP10 22072716 0415 LC PRK1 UBP10 16319894 0415 LC RLP7 UBP10 18467557,18467557 0111,0090 HT WWM1 UBP10 16606443 0089 HT LOC1 UBP10 18467557,18467557 0111,0090 HT TOS3 UBP10 16319894 0415 LC SET2 UBP10 16606443 0089 HT PTK2 UBP10 16319894 0415 LC ATG1 UBP10 16319894 0415 LC PKP2 UBP10 16319894 0415 LC FMP48 UBP10 16319894 0415 LC UTP22 UBP10 26149687,22902402,22902402 0018,0018,0004 LC UBP10 UBP10 18467557,18467557 0090,0111 HT UBP10 MPS1 16319894 0415 LC UBP10 BCK1 16319894 0415 LC UBP10 UBC7 14690591 0397 LC UBP10 SKY1 16319894 0415 LC UBP10 RRP9 18467557,18467557 0111,0090 HT UBP10 NOP6 18467557,18467557 0111,0090 HT UBP10 Q12152 16319894 0415 LC UBP10 DIP2 18467557,18467557 0111,0090 HT UBP10 SKM1 16319894 0415 LC HTB2 UBP10 22902402 0004 LC HSP82 UBP10 19536198,15766533 0676,0004 HT,LC RPL7A UBP10 22902402 0004 LC DED1 UBP10 16429126 0363 HT ADE3 UBP10 22902402 0004 LC URA2 UBP10 22902402 0004 LC SEC53 UBP10 22902402 0004 LC SEC4 UBP10 22902402 0004 LC SPS1 UBP10 21460040 0096 LC PRB1 UBP10 16554755,16554755 0676,0004 HT SSA3 UBP10 19536198 0676 HT RNR2 UBP10 22902402 0004 LC RPL31A UBP10 22902402 0004 LC SSC1 UBP10 19536198 0676 HT RPL18B UBP10 22902402 0004 LC SSA1 UBP10 19536198 0676 HT SSA2 UBP10 19536198,16429126,15766533 0676,0676,0004 HT,LC RPA190 UBP10 22902402,22902402 0415,0004 LC SSB1 UBP10 19536198,15766533 0676,0004 HT,LC SIR4 UBP10 16554755,16554755 0004,0676 HT SUP45 UBP10 22902402 0004 LC URA5 UBP10 22902402 0004 LC SEC63 UBP10 19536198 0676 HT HSC82 UBP10 19536198,15766533,16554755,16554755 0676,0004,0676,0004 HT,LC NOP1 UBP10 22902402 0004 LC POL30 UBP10 22829782 0004 LC HSP26 UBP10 19536198 0676 HT CKA2 UBP10 16554755,16554755 0676,0004 HT HCA4 UBP10 22902402 0004 LC MAK11 UBP10 22902402 0004 LC PWP1 UBP10 22902402 0004 LC TKL1 UBP10 22902402 0004 LC MIR1 UBP10 22902402 0004 LC DBP2 UBP10 22902402 0004 LC SIS1 UBP10 19536198,22902402 0676,0004 HT,LC RRP7 UBP10 16554755,16554755 0676,0004 HT RSA4 UBP10 16554755,16554755 0676,0004 HT PWP2 UBP10 22902402 0004 LC CDC48 UBP10 22902402 0004 LC NSR1 UBP10 22902402 0004 LC URA7 UBP10 22902402 0004 LC SBA1 UBP10 21777812,21777812 0018,0096 LC CAM1 UBP10 22902402 0004 LC PYC2 UBP10 22902402 0004 LC DPH5 UBP10 22902402 0004 LC GCD11 UBP10 22902402 0004 LC SPT16 UBP10 22902402 0004 LC SSE1 UBP10 19536198,15766533 0676,0004 HT,LC SSE2 UBP10 19536198 0676 HT DRS1 UBP10 22902402 0004 LC CNS1 UBP10 15766533 0004 LC CBF5 UBP10 22902402,16554755,16554755 0004,0676,0004 LC,HT HSP78 UBP10 19536198 0676 HT RPS1A UBP10 22902402 0004 LC MRPS5 UBP10 11805826,16429126,11805826,16429126,11805826 0004,0004,0007,0676,0676 HT GCN1 UBP10 22902402 0004 LC BMH2 UBP10 22902402 0004 LC DHR2 UBP10 16554755,16554755,22902402,22902402,17200106,16554755 0363,0676,0018,0004,0004,0004 HT,LC GLY1 UBP10 22902402 0004 LC NOP4 UBP10 22902402 0004 LC NCL1 UBP10 22902402 0004 LC RCK1 UBP10 21460040 0096 LC GND1 UBP10 22902402 0004 LC SSZ1 UBP10 19536198 0676 HT FPR3 UBP10 22902402 0004 LC STM1 UBP10 16554755,16554755 0676,0004 HT CAJ1 UBP10 19536198 0676 HT NOC2 UBP10 22902402 0004 LC BEM2 UBP10 16429126 0363 HT POL5 UBP10 22902402 0004 LC ECM10 UBP10 19536198 0676 HT NUG1 UBP10 22902402 0004 LC UTP7 UBP10 22902402 0004 LC SSB2 UBP10 19536198 0676 HT RPL13B UBP10 22902402 0004 LC MKT1 UBP10 16554755,16554755 0676,0004 HT VMA13 UBP10 22902402 0004 LC UTP10 UBP10 22902402 0004 LC GCN20 UBP10 16554755,16554755 0676,0004 HT SWP82 UBP10 22902402 0004 LC ERJ5 UBP10 19536198 0676 HT GEA1 UBP10 16554755,16554755 0676,0004 HT LYS20 UBP10 22902402 0004 LC ASN2 UBP10 22902402 0004 LC RNR4 UBP10 22902402 0004 LC IMD4 UBP10 22902402 0004 LC ACS2 UBP10 22902402 0004 LC PRP43 UBP10 22902402 0004 LC UTP22 UBP10 22902402,22902402,16554755,16554755 0018,0004,0676,0004 LC,HT NOP7 UBP10 22902402 0004 LC NOP19 UBP10 16554755,16554755 0676,0004 HT UBP10 UBP10 22902402 0004 LC UBP10 NAT10 22902402 0004 LC UBP10 RPA49 16554755,16554755 0676,0004 HT UBP10 NPL3 22902402 0004 LC UBP10 RPL6A 22902402 0004 LC UBP10 NOG1 22902402 0004 LC UBP10 NAN1 22902402 0004 LC UBP10 Q03161 22902402 0004 LC UBP10 HAS1 22902402 0004 LC UBP10 SEC13 22902402 0004 LC UBP10 RRP5 22902402 0004 LC UBP10 UTP13 22902402 0004 LC UBP10 MRD1 22902402 0004 LC UBP10 FPR4 22902402 0004 LC UBP10 DBP9 22902402 0004 LC UBP10 BFR2 22902402 0004 LC UBP10 UTP4 22902402 0004 LC UBP10 SUB2 22902402 0004 LC UBP10 NOP12 22902402 0004 LC UBP10 BRX1 22902402 0004 LC UBP10 ETT1 22902402 0004 LC UBP10 MDN1 22902402 0004 LC UBP10 YRA1 22902402 0004 LC UBP10 MAK21 22902402 0004 LC UBP10 NOP56 22902402 0004 LC UBP10 AIR2 16429126 0363 HT UBP10 NOP58 22902402 0004 LC UBP10 HRP1 22902402 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53874 P53104 UBP10 ATG1 0.183 16319894 P53874 P16892 UBP10 FUS3 0.183 16319894 P53874 P53170 UBP10 PKP2 0.183 16319894 P53874 P23291 UBP10 YCK1 0.183 16319894 P53874 P53233 UBP10 FMP48 0.183 16319894 P53874 P53254 UBP10 UTP22 0.623 16554755,22902402,26149687 P53874 P15992 UBP10 HSP26 0.126 19536198 Q12476 P53874 AIR2 UBP10 0.126 16429126 P53874 P25382 UBP10 RSA4 0.126 16554755 P53874 P17157 UBP10 PHO85 0.183 16319894 P53874 P08458 UBP10 SPS1 0.183 21460040 P53874 P10080 UBP10 SBP1 0.126 23222640 P53874 P00546 UBP10 CDC28 0.183 16319894 P53874 P10591 UBP10 SSA1 0.126 19536198 P53874 P09232 UBP10 PRB1 0.126 16554755 P53874 P12954 UBP10 SRS2 0.183 15964827 P53874 P13186 UBP10 KIN2 0.183 16319894 P53874 P06244 UBP10 TPK1 0.183 16319894 P53874 P06634 UBP10 DED1 0.126 16429126 P53874 P06782 UBP10 SNF1 0.183 16319894 P53874 P02829 UBP10 HSP82 0.236 15766533,19536198 P53874 P15108 UBP10 HSC82 0.416 16554755,15766533,19536198 Q12220 P53874 DIP2 UBP10 0.286 18467557 P53874 P28007 UBP10 GAR1 0.286 18467557 P53874 P28707 UBP10 SBA1 0.332 21777812 P53874 P33750 UBP10 SOF1 0.286 18467557 P53874 P36048 UBP10 SNU114 0.286 18467557 P53874 P24783 UBP10 DBP2 0.236 18467557,22902402 P53874 P10964 UBP10 RPA190 0.286 22902402 P53874 P11978 UBP10 SIR4 0.396 16554755,26149687 P53874 P33322 UBP10 CBF5 0.236 16554755,22902402 P53874 P53874 UBP10 UBP10 0.286 22902402,18467557 P53874 P39744 UBP10 NOC2 0.236 18467557,22902402 P53874 P38622 UBP10 RCK1 0.332 21460040,16319894 P53874 P36009 UBP10 DHR2 0.794 22902402,18467557,26149687,16554755 P53874 P38199 UBP10 HEK2 0.126 18805955 P53874 P38691 UBP10 KSP1 0.183 16319894 P53874 P38779 UBP10 CIC1 0.286 18467557 P53874 P38788 UBP10 SSZ1 0.126 19536198 P53874 P32581 UBP10 IME2 0.183 16319894 P53874 P32589 UBP10 SSE1 0.126 19536198 P53874 P32590 UBP10 SSE2 0.126 19536198 P53874 P39015 UBP10 STM1 0.126 16554755 P53874 P39073 UBP10 SSN3 0.183 16319894 P53874 P39101 UBP10 CAJ1 0.126 19536198 P53874 P27466 UBP10 CMK1 0.183 16319894 P53874 P33203 UBP10 PRP40 0.332 16606443 P53874 P39960 UBP10 BEM2 0.126 16429126 P53874 P33416 UBP10 HSP78 0.126 19536198 P53874 P43582 UBP10 WWM1 0.332 16606443 P53874 P40850 UBP10 MKT1 0.126 16554755 P53874 P40693 UBP10 RLP7 0.126 18467557 P53874 P40494 UBP10 PRK1 0.183 16319894 P53874 P46995 UBP10 SET2 0.332 16606443 P53874 P47102 UBP10 GEA1 0.126 16554755 P53874 P47116 UBP10 PTK2 0.183 16319894 P53874 P14681 UBP10 KSS1 0.183 16319894 Q01389 P53874 BCK1 UBP10 0.183 16319894 P53874 P19454 UBP10 CKA2 0.236 16554755 P53874 P43535 UBP10 GCN20 0.126 16554755 Q03656 P53874 SKY1 UBP10 0.183 16319894 Q07623 P53874 NOP6 UBP10 0.126 18467557 P53874 P02293 UBP10 HTB1 0.309 26149687 P53874 P02294 UBP10 HTB2 0.126 22902402 P53874 P05737 UBP10 RPL7A 0.126 22902402 P53874 P07245 UBP10 ADE3 0.126 22902402 P53874 P07259 UBP10 URA2 0.126 22902402 P53874 P07283 UBP10 SEC53 0.126 22902402 P53874 P07560 UBP10 SEC4 0.126 22902402 P53874 P09435 UBP10 SSA3 0.126 19536198 P53874 P09938 UBP10 RNR2 0.126 22902402 P53874 P0C2H8 UBP10 RPL31A 0.126 22902402 P53874 P0CS90 UBP10 SSC1 0.126 19536198 P53874 P0CX49 UBP10 RPL18A 0.126 22902402 P53874 P0CX50 UBP10 RPL18B 0.126 22902402 P53874 P10592 UBP10 SSA2 0.236 16429126,19536198 P53874 P11484 UBP10 SSB1 0.126 19536198 P53874 P12385 UBP10 SUP45 0.126 22902402 P53874 P13298 UBP10 URA5 0.126 22902402 P53874 P14906 UBP10 SEC63 0.126 19536198 P53874 P15646 UBP10 NOP1 0.126 22902402 P53874 P15873 UBP10 POL30 0.376 22829782 P53874 P20448 UBP10 HCA4 0.126 22902402 P53874 P20484 UBP10 MAK11 0.126 22902402 P53874 P21304 UBP10 PWP1 0.126 22902402 P53874 P22696 UBP10 ESS1 0.332 16606443 P53874 P23254 UBP10 TKL1 0.126 22902402 P53874 P23641 UBP10 MIR1 0.126 22902402 P53874 P25294 UBP10 SIS1 0.236 22902402,19536198 P53874 P25368 UBP10 RRP7 0.126 16554755 P53874 P25635 UBP10 PWP2 0.236 22902402 P53874 P25694 UBP10 CDC48 0.126 22902402 P53874 P27476 UBP10 NSR1 0.126 22902402 P53874 P28274 UBP10 URA7 0.126 22902402 P53874 P29547 UBP10 CAM1 0.126 22902402 P53874 P32327 UBP10 PYC2 0.126 22902402 P53874 P32469 UBP10 DPH5 0.126 22902402 P53874 P32481 UBP10 GCD11 0.126 22902402 P53874 P32558 UBP10 SPT16 0.126 22902402 P53874 P32892 UBP10 DRS1 0.126 22902402 P53874 P33442 UBP10 RPS1A 0.126 22902402 P53874 P33759 UBP10 MRPS5 0.416 11805826,16429126 P53874 P33892 UBP10 GCN1 0.126 22902402 P53874 P34730 UBP10 BMH2 0.126 22902402 P53874 P37303 UBP10 GLY1 0.126 22902402 P53874 P37838 UBP10 NOP4 0.126 22902402 P53874 P38205 UBP10 NCL1 0.126 22902402 P53874 P38720 UBP10 GND1 0.126 22902402 P53874 P38911 UBP10 FPR3 0.126 22902402 P53874 P39985 UBP10 POL5 0.126 22902402 P53874 P39987 UBP10 ECM10 0.126 19536198 P53874 P40010 UBP10 NUG1 0.126 22902402 P53874 P40055 UBP10 UTP7 0.126 22902402 P53874 P40150 UBP10 SSB2 0.126 19536198 P53874 P40212 UBP10 RPL13B 0.126 22902402 P53874 P40316 UBP10 PDS1 0.309 22072716 P53874 P41807 UBP10 VMA13 0.126 22902402 P53874 P42945 UBP10 UTP10 0.126 22902402 P53874 P43554 UBP10 SWP82 0.126 22902402 P53874 P43586 UBP10 LOC1 0.126 18467557 P53874 P43613 UBP10 ERJ5 0.126 19536198 P53874 P48570 UBP10 LYS20 0.126 22902402 P53874 P49090 UBP10 ASN2 0.126 22902402 P53874 P49723 UBP10 RNR4 0.126 22902402 P53874 P50094 UBP10 IMD4 0.126 22902402 P53874 P52910 UBP10 ACS2 0.126 22902402 P53874 P53131 UBP10 PRP43 0.126 22902402 P53874 P53261 UBP10 NOP7 0.126 22902402 P53874 P53317 UBP10 NOP19 0.126 16554755 P53914 P53874 KRE33 UBP10 0.126 22902402 Q01080 P53874 RPA49 UBP10 0.126 16554755 Q01560 P53874 NPL3 UBP10 0.126 22902402 Q02159 P53874 UBC7 UBP10 0.126 14690591 Q02326 P53874 RPL6A UBP10 0.126 22902402 Q02892 P53874 NOG1 UBP10 0.126 22902402 Q02931 P53874 NAN1 UBP10 0.126 22902402 Q03161 P53874 Q03161 UBP10 0.126 22902402 Q03532 P53874 HAS1 UBP10 0.126 22902402 Q04491 P53874 SEC13 UBP10 0.126 22902402 Q05022 P53874 RRP5 UBP10 0.126 22902402 Q05946 P53874 UTP13 UBP10 0.126 22902402 Q06106 P53874 MRD1 UBP10 0.126 22902402 Q06205 P53874 FPR4 UBP10 0.126 22902402 Q06218 P53874 DBP9 UBP10 0.126 22902402 Q06506 P53874 RRP9 UBP10 0.126 18467557 Q06631 P53874 BFR2 UBP10 0.126 22902402 Q06679 P53874 UTP4 UBP10 0.126 22902402 Q07478 P53874 SUB2 UBP10 0.126 22902402 Q08208 P53874 NOP12 UBP10 0.126 22902402 Q08235 P53874 BRX1 UBP10 0.126 22902402 Q08421 P53874 ETT1 UBP10 0.126 22902402 Q12019 P53874 MDN1 UBP10 0.126 22902402 Q12159 P53874 YRA1 UBP10 0.126 22902402 Q12176 P53874 MAK21 UBP10 0.126 22902402 Q12460 P53874 NOP56 UBP10 0.126 22902402 Q12499 P53874 NOP58 UBP10 0.126 22902402 Q99383 P53874 HRP1 UBP10 0.126 22902402 P54199 P53874 MPS1 UBP10 0.183 16319894 P53874 P22216 UBP10 RAD53 0.183 16319894