PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SWT21 CBC2 21558325 biogrid exp CBF5 SWT21 21558325 biogrid exp CPR8 SWT21 11283351 i2d,mint,intact,dip exp CRM1 SWT21 26673895 biogrid exp SSA1 SWT21 19536198 intact exp MUD1 SWT21 21558325 biogrid exp SWT21 NAM8 21558325 biogrid exp NAM7 SWT21 18087042 biogrid exp MCK1 SWT21 16319894, 23023127 biogrid,i2d exp, pred SIT4 SWT21 11805826,16429126, 23023127 biogrid,mint,intact,dip exp, pred SWT21 NDE2 18467557, 23023127 biogrid,i2d,mint,intact exp, pred SMB1 SWT21 9207794, 23023127 biogrid,i2d,dip exp, pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P53873 - 11805826 - C 15 P53728 P53873 - 11283351 - X 2 P40018 P53873 - 9207794 - X 2 Q08920 P53873 affinity chromatography technology 21558325 physical association X 2 P33322 P53873 affinity chromatography technology 21558325 physical association X 2 P20604 P53873 affinity chromatography technology 11805826 physical association X 2 P32605 P53873 affinity chromatography technology 21558325 physical association X 2 Q00539 P53873 affinity chromatography technology 21558325 physical association X 2 Q07500 P53873 protein complementation assay 18467557 direct interaction X 2 P40018 P53873 two hybrid 9207794 direct interaction X 2 P53873 P21965 enzymatic study 16319894 direct interaction X 2 P20604 P53873 tandem affinity purification 11805826 physical association X 2 P53873 tandem affinity purification 11805826 physical association C 15 P53873 inferred by author 11805826 physical association C 15 P53728 P53873 two hybrid pooling approach 11283351 physical association X 2 P40018 P53873 two hybrid 9207794 physical association X 2 P53873 tandem affinity purification 11805826 association C 16 P10591 P53873 tandem affinity purification 19536198 association X 2 P53873 tandem affinity purification 16429126 association C 23 P53728 P53873 two hybrid fragment pooling approach 11283351 physical association X 2 Q07500 P53873 dihydrofolate reductase reconstruction 18467557 physical association X 2 P53873 mass spectrometry studies of complexes 11805826 - C 16 P53728 P53873 two hybrid 11283351 - X 2 P40018 P53873 two hybrid 9207794 - X 2

PPI - HINT Gene A Gene B PMID Method Quality MCK1 SWT21 16319894 0415 LC SMB1 SWT21 9207794 0018 HT CPR8 SWT21 11283351,11283351,11283351 0018,0399,0398 HT SWT21 NDE2 18467557,18467557 0111,0090 HT SSA1 SWT21 19536198 0676 HT SIT4 SWT21 11805826,16429126,11805826,11805826 0004,0676,0007,0676 HT CRM1 SWT21 26673895,26673895 0096,0004 LC MUD1 SWT21 21558325 0004 LC CBF5 SWT21 21558325 0004 LC SWT21 NAM8 21558325 0004 LC SWT21 CBC2 21558325 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53873 P10591 SWT21 SSA1 0.126 19536198 Q07500 P53873 NDE2 SWT21 0.286 18467557 P53873 P30822 SWT21 CRM1 0.236 26673895 P53873 P30771 SWT21 NAM7 0.126 18087042 P53873 P33322 SWT21 CBF5 0.126 21558325 P53873 P20604 SWT21 SIT4 0.332 11805826,16429126 P53873 P40018 SWT21 SMB1 0.033 9207794 P53873 P53728 SWT21 CPR8 0.21 11283351 P53873 P21965 SWT21 MCK1 0.183 16319894 Q08920 P53873 CBC2 SWT21 0.126 21558325