PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RTF1 CRT10 25534857 biogrid exp PRP43 CRT10 i2d exp LEO1 CRT10 25534857 biogrid exp VAM6 CRT10 25026036 biogrid exp GCN5 CRT10 21734642 biogrid,intact exp TAF5 CRT10 21734642 biogrid,intact exp SOL1 CRT10 16429126 intact exp CRT10 HRT1 25534857,19882662 biogrid,intact exp CDC73 CRT10 25534857 biogrid exp PUF3 CRT10 23409723 biogrid exp PRP16 CRT10 10688190 mint,intact,dip exp MMS1 CRT10 25534857 biogrid exp CDC34 CRT10 16554755 biogrid,i2d,mint,intact exp SSB2 CRT10 19536198 intact exp WHI3 CRT10 18667435 biogrid exp PAF1 CRT10 25534857 biogrid exp YVH1 CRT10 20489023 biogrid,mint,intact exp CRM1 CRT10 26673895 biogrid exp CTR9 CRT10 25534857 biogrid exp HMT1 CRT10 14690591 intact exp CAK1 CRT10 16554755 intact exp GLC7 CRT10 14660704 intact exp PSA1 CRT10 i2d exp MGA1 CRT10 11283351, 23023127 i2d,mint,intact,dip exp, pred RTT101 CRT10 25534857,18704118, 23023127 biogrid,mint,intact exp, pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q08226 P53050 - 11283351 - X 2 Q02256 Q08226 affinity chromatography technology 20489023 physical association X 2 P0CG63 Q08226 affinity chromatography technology 23749301 physical association X 2 P0CG63 Q08226 affinity chromatography technology 17644757 physical association X 2 P0CG63 Q08226 affinity chromatography technology 23793018 physical association X 2 P0CG63 Q08226 affinity chromatography technology 12872131 physical association X 2 Q08226 Q03330 affinity chromatography technology 21734642 physical association X 2 P14682 Q08226 affinity chromatography technology 16554755 physical association X 2 Q08226 P47050 affinity chromatography technology 17200106 physical association X 2 Q08226 P47050 affinity chromatography technology 18704118 physical association X 2 Q08226 P38129 affinity chromatography technology 21734642 physical association X 2 Q08226 P53050 two hybrid pooling approach 11283351 physical association X 2 Q08226 P15938 two hybrid 10688190 physical association X 2 Q08226 tandem affinity purification 21734642 association C 157 Q08226 pull down 19882662 association C 41 Q08226 inferred by author 16554755 association C 12 Q08226 tandem affinity purification 21734642 association C 136 Q08226 anti tag coimmunoprecipitation 20489023 association C 12 Q08226 tandem affinity purification 14660704 association C 27 Q08226 P53050 two hybrid fragment pooling approach 11283351 physical association X 2 P38074 Q08226 two hybrid array 14690591 physical association X 2 Q08226 tandem affinity purification 16429126 association C 16 P14682 Q08226 tandem affinity purification 16554755 physical association X 2 P14682 Q08226 tandem affinity purification 16554755 physical association X 2 P14682 Q08226 tandem affinity purification 16554755 physical association X 2 P14682 Q08226 tandem affinity purification 16554755 physical association X 2 Q08226 P15938 two hybrid 10688190 physical association X 2 Q08226 P47050 pull down 18704118 physical association X 2 Q08226 P40150 tandem affinity purification 19536198 association X 2 Q08226 P53050 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality PRP16 CRT10 10688190 0018 HT HMT1 CRT10 14690591 0397 LC MGA1 CRT10 11283351,11283351,11283351 0018,0399,0398 HT CDC34 CRT10 16554755,16554755 0676,0004 HT CRM1 CRT10 26673895,26673895 0096,0004 LC GLC7 CRT10 14660704 0676 HT TAF5 CRT10 21734642,21734642 0676,0004 LC PAF1 CRT10 25534857 0004 LC LEO1 CRT10 25534857 0004 LC SSB2 CRT10 19536198 0676 HT CAK1 CRT10 16554755 0363 HT RTT101 CRT10 17200106,18704118,25534857,18704118 0004,0004,0004,0096 HT,LC SOL1 CRT10 16429126 0676 HT RTF1 CRT10 25534857 0004 LC CTR9 CRT10 25534857 0004 LC YVH1 CRT10 20489023,20489023 0007,0004 HT GCN5 CRT10 21734642,21734642 0676,0004 LC MMS1 CRT10 25534857 0004 LC CDC73 CRT10 25534857 0004 LC CRT10 HRT1 19882662,25534857 0096,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q08226 P53050 CRT10 MGA1 0.21 11283351 Q08226 Q03330 CRT10 GCN5 0.236 21734642 Q08226 P38129 CRT10 TAF5 0.236 21734642 Q08226 P30822 CRT10 CRM1 0.126 26673895 Q08226 P38351 CRT10 PAF1 0.376 25534857 Q08226 P38439 CRT10 LEO1 0.376 25534857 Q08226 P32598 CRT10 GLC7 0.126 14660704 Q08226 P34761 CRT10 WHI3 0.183 18667435 Q08226 P43568 CRT10 CAK1 0.126 16554755 Q08226 P50278 CRT10 SOL1 0.126 16429126 Q08226 Q06211 CRT10 MMS1 0.376 25534857 Q08226 P14682 CRT10 CDC34 0.332 16554755 Q08226 P15938 CRT10 PRP16 0.183 10688190 Q08226 P38074 CRT10 HMT1 0.126 14690591 Q08226 P40150 CRT10 SSB2 0.126 19536198 Q08226 P47050 CRT10 RTT101 0.597 18704118,25534857 Q08226 P53064 CRT10 RTF1 0.21 25534857 Q08226 P89105 CRT10 CTR9 0.21 25534857 Q08226 Q02256 CRT10 YVH1 0.332 20489023 Q08226 Q06697 CRT10 CDC73 0.21 25534857 Q08273 Q08226 HRT1 CRT10 0.376 19882662,25534857