PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SSA2 BUB3 19536198 intact exp BUB3 NOP6 23894419 biogrid exp BUB3 Uncharacterized protein YGR130C 23894419 biogrid exp BUB3 OKP1 14633972 biogrid exp UBI4 BUB3 21070969 biogrid exp BUB3 KOG1 23894419 biogrid exp BUB3 RVB2 23894419 biogrid exp TEF1, TEF2 BUB3 16429126 intact exp ARG3 BUB3 11805837 dip exp BUB3 DSN1 21107429,24402315 biogrid exp BUB3 SDS22 23894419 biogrid exp BIK1 BUB3 i2d exp BUB3 SSB2 23332755 biogrid exp BUB3 RPN11 20170199,18757749 biogrid exp BUB3 RVB1 23894419 biogrid exp BUB3 NUS1 10688190 dip exp SIS1 BUB3 19536198 intact exp SNF4 BUB3 23894419 biogrid exp BUB3 SPC105 22521787 biogrid exp SSB1 BUB3 19536198 intact exp BUB3 GSY2 11805837 biogrid,mint,intact,dip exp BUB3 BMH2 11805837 dip exp BUB3 CIN8 i2d exp BUB3 BIM1 i2d exp BUB3 Putative uncharacterized protein Q0092, mitochondrial 11805837, 23023127 mint,intact exp, pred CDC20 BUB3 11726501,15879521,14660704, 23023127 biogrid,intact exp, pred BUB3 MAD3 10704439,20498086,15879521,17406666,18719252,11726501,10688190,15644329,17227844, 23023127 biogrid,i2d,mint,intact,dip exp, pred BUB3 BUB1 10704439,20489023,16429126,12221113,23267104,11283351,10837255,18719252,7969164,24066227,11726501,15644329,10688190,17634282,12944469, 23023127 biogrid,i2d,mint,intact,dip exp, pred BUB3 MAD1 21098112,11726501,10837255, 23023127 biogrid,intact exp, pred BUB3 MAD2 11726501,15879521, 23023127 biogrid,intact exp, pred BUB3 CDC27 15879521, 23023127 intact exp, pred BUB3 CDC55 23023127 pred BUB3 SKI8 23023127 pred RAD9 BUB3 23023127 pred

PPI - HINT Gene A Gene B PMID Method Quality CDC20 BUB3 15879521,15879521 0401,0071 LC BUB3 BUB3 15544799 0114 LC BUB3 SDS22 23894419,23894419 0018,0096 LC BUB3 CDC27 15879521 0071 LC BUB3 SSB2 23332755 0401 LC BUB3 MAD2 15879521,15879521 0071,0007 LC BUB3 BUB1 17227844,7969164,24066227,11283351,10704439,11283351,10688190,23267104,17634282,12221113,12221113,18719252,7969164,11283351,7969164,17227844,7969164,11726501 0114,0004,0114,0398,0018,0399,0018,0946,0018,0018,0004,0018,0415,0018,0019,0065,0096,0071 LC,HT BUB3 MAD3 18719252,17227844,17227844,15879521,10704439,20498086,17227844,17227844,10704439,17227844,10704439,10704439,10704439,10688190,10704439,10688190 0018,0071,0114,0071,0004,0114,0028,0096,0019,0065,0018,0007,0006,0397,0096,0018 HT,LC BUB3 NUS1 10688190 0018 HT TEF1|TEF2 BUB3 16429126 0676 HT ARG3 BUB3 11805837 0007 HT UBI4 BUB3 21070969,21070969 0004,0096 LC SSA2 BUB3 19536198 0676 HT SSB1 BUB3 19536198 0676 HT SNF4 BUB3 23894419 0096 LC SIS1 BUB3 19536198 0676 HT CDC20 BUB3 15879521,11726501,14660704,11726501,15879521 0401,0007,0004,0004,0071 LC,HT BUB3 GSY2 11805837,11805837 0004,0007 HT BUB3 BMH2 11805837 0007 HT BUB3 SDS22 23894419,23894419 0018,0096 LC BUB3 KOG1 23894419 0096 LC BUB3 SSB2 23332755 0401 LC BUB3 DSN1 21107429,24402315 0004,0004 HT,LC BUB3 MAD1 11726501,10837255,11726501,10837255,10837255,21098112 0007,0004,0004,0006,0007,0004 LC BUB3 MAD2 11726501,11726501,15879521,15879521 0007,0004,0071,0007 LC BUB3 BUB1 10837255,7969164,20489023,10837255,16429126,15644329,12944469,20489023,12221113,12221113,7969164,10837255,7969164,7969164 0007,0004,0007,0006,0676,0004,0428,0004,0018,0004,0415,0004,0019,0096 LC,HT BUB3 RPN11 20170199,18757749 0004,0004 LC,HT BUB3 MAD3 17227844,17227844,10704439,11726501,15644329,17227844,17227844,10704439,17227844,10704439,10704439,10704439,10704439,17406666 0071,0114,0004,0007,0004,0028,0096,0019,0065,0018,0007,0006,0096,0004 LC BUB3 SPC105 22521787 0004 LC BUB3 P53278 23894419 0096 LC BUB3 OKP1 14633972 0004 LC BUB3 RVB1 23894419 0096 LC BUB3 NOP6 23894419 0096 LC BUB3 RVB2 23894419 0096 LC BUB3 Q35811 11805837 0007 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P53148 P26449 SPC105 BUB3 0.21 22521787 P53278 P26449 P53278 BUB3 0.309 23894419 Q12063 P26449 NUS1 BUB3 0.033 10688190 Q12221 P26449 PUF2 BUB3 0.126 26668354 Q12464 P26449 RVB2 BUB3 0.309 23894419 P26449 P0CG63 BUB3 UBI4 0.309 21070969 P26449 P12904 BUB3 SNF4 0.309 23894419 P26449 P05150 BUB3 ARG3 0.126 11805837 P43588 P26449 RPN11 BUB3 0.236 20170199,18757749 P26449 P26309 BUB3 CDC20 0.702 15879521,11726501,14660704 P40958 P26449 MAD2 BUB3 0.507 15879521,11726501 P47074 P26449 MAD3 BUB3 0.976 10688190,15879521,17406666,15644329,11726501,20498086,10704439,17227844,18719252 P41695 P26449 BUB1 BUB3 0.973 10688190,23267104,10837255,24066227,20489023,18719252,12221113,17634282,16429126,15644329,11283351,12944469,11726501,7969164,10704439 P26449 P11484 BUB3 SSB1 0.126 19536198 P26449 P10592 BUB3 SSA2 0.126 19536198 P26449 P02994 BUB3 TEF2 0.126 16429126 P26449 P25294 BUB3 SIS1 0.126 19536198 P38042 P26449 CDC27 BUB3 0.21 15879521 Q35811 P26449 Q35811 BUB3 0.126 11805837 P38873 P26449 KOG1 BUB3 0.309 23894419 P27472 P26449 GSY2 BUB3 0.332 11805837 P40150 P26449 SSB2 BUB3 0.126 23332755 P34730 P26449 BMH2 BUB3 0.126 11805837 P36047 P26449 SDS22 BUB3 0.671 23894419 P40568 P26449 DSN1 BUB3 0.21 24402315 P40957 P26449 MAD1 BUB3 0.61 11726501,10837255,21098112 Q07623 P26449 NOP6 BUB3 0.309 23894419 Q03940 P26449 RVB1 BUB3 0.309 23894419