PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q12380 - 11805837 - C 4 O13547 Q12380 - 11283351 - X 2 P38316 Q12380 - 10688190 - X 2 P38316 Q12380 - 11283351 - X 2 Q12380 Q03818 - 11283351 - X 2 Q12380 Q03818 - 10688190 - X 2 P40344 Q12380 enzymatic study 17986448 direct interaction X 2 P40344 Q12380 pull down 17986448 direct interaction X 2 Q12380 P38255 affinity chromatography technology 20489023 physical association X 2 Q12380 P08524 affinity chromatography technology 11805837 physical association X 2 Q12380 P38993 affinity chromatography technology 11805837 physical association X 2 P38316 Q12380 pull down 23064152 direct interaction X 2 P38316 Q12380 affinity chromatography technology 11149920 physical association X 2 P38316 Q12380 pull down 11139573 direct interaction X 2 P38316 Q12380 two hybrid 10406794 direct interaction X 2 P38316 Q12380 pull down 9759731 direct interaction X 2 P38316 Q12380 x-ray crystallography 23238393 association X 2 P38316 Q12380 pull down 25461810 direct interaction X 2 P38316 Q12380 two hybrid 11283351 direct interaction X 2 P38316 Q12380 two hybrid 10688190 direct interaction X 2 P31373 Q12380 affinity chromatography technology 11805837 physical association X 2 Q12380 Q03818 pull down 23064152 direct interaction X 2 Q12380 Q03818 affinity chromatography technology 10406794 physical association X 2 Q12380 Q03818 affinity chromatography technology 10406794 physical association X 2 Q12380 Q03818 two hybrid 10406794 direct interaction X 2 Q12380 P38182 enzymatic study 17986448 direct interaction X 2 Q12380 Q03818 biochemical 17986448 colocalization X 2 Q12380 Q03818 x-ray crystallography 17012802 association X 2 Q12380 Q03818 two hybrid 11283351 direct interaction X 2 Q12380 Q03818 x-ray crystallography 17192262 association X 2 Q12380 Q03818 two hybrid 18719252 direct interaction X 2 Q12380 P12904 two hybrid 18719252 direct interaction X 2 Q12380 P07278 two hybrid 18719252 direct interaction X 2 Q12380 P43634 two hybrid 18719252 direct interaction X 2 Q12380 Q03818 biochemical 19889643 association X 2 Q12380 Q03818 pull down 19889643 direct interaction X 2 Q12380 Q03818 two hybrid 10688190 direct interaction X 2 Q12380 anti tag coimmunoprecipitation 11805837 - C 23 Q12380 anti tag coimmunoprecipitation 11805837 - C 4 P19882 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 P04807 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 P04385 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 P32861 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P11154 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P0CS90 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P02557 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P08524 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P38993 anti tag coimmunoprecipitation 11805837 physical association X 2 P16474 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 P00358 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 P06168 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 P00360 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 P04397 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 O13547 Q12380 two hybrid pooling approach 11283351 physical association X 2 P38316 Q12380 two hybrid 10688190 physical association X 2 P38316 Q12380 two hybrid 10688190 physical association X 2 P38316 Q12380 coimmunoprecipitation 11897782 physical association X 2 P38316 Q12380 coimmunoprecipitation 9759731 physical association X 2 P38316 Q12380 two hybrid pooling approach 11283351 physical association X 2 P38316 Q12380 two hybrid 10688190 physical association X 2 P05694 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 P31373 Q12380 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 Q03818 two hybrid 10688190 physical association X 2 Q12380 Q03818 two hybrid pooling approach 11283351 physical association X 2 Q12380 P53090 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P07251 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P32582 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P14540 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P17709 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 P04806 anti tag coimmunoprecipitation 11805837 physical association X 2 Q12380 anti tag coimmunoprecipitation 20489023 association C 7 Q12380 anti tag coimmunoprecipitation 11805837 association C 4 P32589 Q12380 tandem affinity purification 19536198 association X 2 P11484 Q12380 tandem affinity purification 19536198 association X 2 Q12380 P31539 tandem affinity purification 19536198 association X 2 Q12380 anti tag coimmunoprecipitation 10406794 physical association C 3 Q12380 two hybrid 10406794 physical association C 3 Q12380 anti tag coimmunoprecipitation 10406794 physical association C 3 Q12380 x-ray crystallography 23238393 physical association C 3 O13547 Q12380 two hybrid fragment pooling approach 11283351 physical association X 2 P38316 Q12380 two hybrid 10406794 physical association X 2 P38316 Q12380 two hybrid 10688190 physical association X 2 P38316 Q12380 two hybrid fragment pooling approach 11283351 physical association X 2 P38316 Q12380 two hybrid array 14690591 physical association X 2 P38316 Q12380 anti tag coimmunoprecipitation 23064152 physical association X 2 P38316 Q12380 anti tag coimmunoprecipitation 9759731 physical association X 2 P38316 Q12380 cosedimentation through density gradient 9759731 physical association X 2 P40150 Q12380 tandem affinity purification 19536198 association X 2 P14904 Q12380 fluorescence microscopy 23064152 colocalization X 2 P10591 Q12380 tandem affinity purification 19536198 association X 2 Q12380 Q03818 two hybrid 10406794 physical association X 2 Q12380 Q03818 two hybrid 10688190 physical association X 2 Q12380 Q03818 two hybrid fragment pooling approach 11283351 physical association X 2 Q12380 P12904 two hybrid 18719252 physical association X 2 Q12380 P07278 two hybrid 18719252 physical association X 2 Q12380 P43634 two hybrid 18719252 physical association X 2 Q12380 Q03818 two hybrid 18719252 physical association X 2 Q12380 mass spectrometry studies of complexes 11805837 - C 5 Q12380 mass spectrometry studies of complexes 11805837 - C 5 O13547 Q12380 two hybrid 11283351 - X 2 P38316 Q12380 two hybrid 11283351 - X 2 P38316 Q12380 interaction detection method - - X 2 P38316 Q12380 two hybrid 10688190 - X 2 Q12380 P38862 interaction detection method - - X 2 Q12380 Q03818 two hybrid 11283351 - X 2 Q12380 Q03818 two hybrid 10688190 - X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q12380 P53090 ATG5 ARO8 0.126 11805837 Q12380 O13547 ATG5 CCW14 0.21 11283351 Q12380 P00360 ATG5 TDH1 0.126 11805837 Q12380 P04397 ATG5 GAL10 0.126 11805837 Q12380 P04807 ATG5 HXK2 0.126 11805837 Q12380 P06168 ATG5 ILV5 0.126 11805837 Q12380 P08524 ATG5 ERG20 0.236 11805837 Q12380 P12904 ATG5 SNF4 0.332 18719252 Q12380 P14904 ATG5 LAP4 0.126 23064152 Q12380 P16474 ATG5 KAR2 0.126 11805837 Q12380 P19882 ATG5 HSP60 0.126 11805837 Q12380 P31373 ATG5 CYS3 0.21 11805837 Q12380 P38182 ATG5 ATG8 0.309 17986448 Q12380 P38993 ATG5 FET3 0.21 11805837 Q12380 P10591 ATG5 SSA1 0.126 19536198 Q12380 P11154 ATG5 PYC1 0.126 11805837 Q12380 P02557 ATG5 TUB2 0.126 11805837 Q12380 P11484 ATG5 SSB1 0.126 19536198 Q12380 P12398 ATG5 SSC1 0.126 11805837 Q12380 P00358 ATG5 TDH2 0.126 11805837 Q12380 P04385 ATG5 GAL1 0.126 11805837 Q12380 P14540 ATG5 FBA1 0.126 11805837 Q12380 P04806 ATG5 HXK1 0.126 11805837 Q12380 P05694 ATG5 MET6 0.126 11805837 Q12380 P07251 ATG5 ATP1 0.126 11805837 Q12380 Q03818 ATG5 ATG16 0.917 10688190,23064152,10406794,18719252,17986448,11283351 Q12380 P07278 ATG5 BCY1 0.332 18719252 Q12380 P30822 ATG5 CRM1 0.236 26673895 Q12380 P40344 ATG5 ATG3 0.523 17986448 Q12380 P38316 ATG5 ATG12 0.964 10688190,11897782,25461810,23064152,14690591,23238393,10406794,11283351,9759731 Q12380 P31539 ATG5 HSP104 0.126 19536198 Q12380 P38255 ATG5 RXT2 0.286 20489023 Q12380 P32505 ATG5 NAB2 0.126 19840948 Q12380 P32582 ATG5 CYS4 0.126 11805837 Q12380 P32589 ATG5 SSE1 0.126 19536198 Q12380 P32861 ATG5 UGP1 0.126 11805837 Q12380 P40150 ATG5 SSB2 0.126 19536198 Q12380 P43634 ATG5 CHA4 0.332 18719252 Q12380 P17709 ATG5 GLK1 0.126 11805837 Q12380 P49760 ATG5 CLK2 0.332 27107014