PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SSB1 UBA3 19536198 intact exp SSA2 UBA3 19536198 intact exp PUF3 UBA3 26493364 biogrid exp NAB2 UBA3 19840948 biogrid exp CDC34 UBA3 i2d exp PCD1 UBA3 11283351 i2d,mint,intact,dip exp SSE1 UBA3 19536198 intact exp PRP19 UBA3 21386897, 23023127 biogrid,intact exp, pred UBA3 UBA3 11805826, 23023127 mint,intact exp, pred SUA7 UBA3 11283351, 23023127 i2d,mint,intact,dip exp, pred ULA1 UBA3 20826334,11805826,16429126,10688190,11283351,9545234,18719252, 23023127 biogrid,i2d,mint,intact,dip exp, pred RUB1 UBA3 9545234, 23023127 biogrid exp, pred UBC12 UBA3 23023127 pred AOS1 UBA3 23023127 pred UBC11 UBA3 23023127 pred UBA1 UBA3 23023127 pred UBP6 UBA3 23023127 pred UBA2 UBA3 23023127 pred SMT3 UBA3 23023127 pred

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q12059 Q99344 - 11805826 - X 2 Q12059 Q99344 - 15044803 - X 2 Q12059 Q99344 - 10688190 - X 2 Q12059 Q99344 - 11283351 - X 2 Q12524 Q99344 - 11283351 - X 2 P29055 Q99344 - 11283351 - X 2 Q12059 Q99344 pull down 9545234 direct interaction X 2 Q12059 Q99344 affinity chromatography technology 16429126 physical association X 2 Q12059 Q99344 affinity chromatography technology 16429126 physical association X 2 Q12059 Q99344 affinity chromatography technology 17200106 physical association X 2 Q12059 Q99344 two hybrid 11283351 direct interaction X 2 Q12059 Q99344 two hybrid 18719252 direct interaction X 2 Q12059 Q99344 affinity chromatography technology 20826334 physical association X 2 Q12059 Q99344 affinity chromatography technology 11805826 physical association X 2 Q12059 Q99344 two hybrid 10688190 direct interaction X 2 P0CG63 Q99344 biochemical 23583075 association X 2 P32523 Q99344 two hybrid 21386897 direct interaction X 2 Q99344 Q03919 pull down 9545234 direct interaction X 2 Q99344 Q03919 pull down 9545234 direct interaction X 2 Q12059 Q99344 two hybrid 10688190 physical association X 2 Q12059 Q99344 tandem affinity purification 11805826 physical association X 2 Q12059 Q99344 two hybrid pooling approach 11283351 physical association X 2 Q12059 Q99344 inferred by author 11805826 physical association X 2 Q12524 Q99344 two hybrid pooling approach 11283351 physical association X 2 P29055 Q99344 two hybrid pooling approach 11283351 physical association X 2 Q99344 tandem affinity purification 16429126 association C 3 Q99344 tandem affinity purification 11805826 association C 3 Q99344 tandem affinity purification 11805826 association C 3 Q12059 Q99344 two hybrid 10688190 physical association X 2 Q12059 Q99344 two hybrid fragment pooling approach 11283351 physical association X 2 Q12059 Q99344 tandem affinity purification 16429126 physical association X 2 Q12059 Q99344 inferred by author 16429126 physical association X 2 Q12059 Q99344 two hybrid 18719252 physical association X 2 Q12524 Q99344 two hybrid fragment pooling approach 11283351 physical association X 2 Q99344 enzymatic study 18796637 ubiquitination reaction C 4 P10592 Q99344 tandem affinity purification 19536198 association X 2 P32589 Q99344 tandem affinity purification 19536198 association X 2 P11484 Q99344 tandem affinity purification 19536198 association X 2 P32523 Q99344 two hybrid 21386897 physical association X 2 P29055 Q99344 two hybrid fragment pooling approach 11283351 physical association X 2 Q99344 mass spectrometry studies of complexes 11805826 - C 3 Q99344 mass spectrometry studies of complexes 11805826 - C 3 Q12059 Q99344 two hybrid 10688190 - X 2 Q12059 Q99344 two hybrid 11283351 - X 2 Q12524 Q99344 two hybrid 11283351 - X 2 P14682 Q99344 interaction detection method 9545234 - X 2 P29055 Q99344 two hybrid 11283351 - X 2

PPI - HINT Gene A Gene B PMID Method Quality SUA7 UBA3 11283351,11283351,11283351 0018,0399,0398 HT PRP19 UBA3 21386897 0018 LC ULA1 UBA3 18719252,11283351,11283351,11283351,10688190,10688190 0018,0018,0399,0398,0397,0018 HT PCD1 UBA3 11283351,11283351,11283351 0018,0399,0398 HT SSA2 UBA3 19536198 0676 HT SSB1 UBA3 19536198 0676 HT NAB2 UBA3 19840948 0004 LC SSE1 UBA3 19536198 0676 HT RUB1 UBA3 20832729,9545234 0004,0096 LC ULA1 UBA3 9545234,11805826,16429126,16429126,11805826,11805826,11805826,17200106,16429126,20826334 0096,0007,0676,0363,0676,0363,0004,0004,0004,0004 LC,HT UBA3 UBA3 11805826,11805826 0676,0007 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q99344 P11484 UBA3 SSB1 0.126 19536198 Q99344 P32523 UBA3 PRP19 0.332 21386897 Q9Y2J4 Q99344 AMOTL2 UBA3 0.332 27107014 Q99344 Q12059 UBA3 ULA1 0.908 11805826,10688190,9545234,16429126,18719252,11283351,20826334 Q99344 P32505 UBA3 NAB2 0.126 19840948 Q99344 P10592 UBA3 SSA2 0.126 19536198 Q99344 Q03919 UBA3 RUB1 0.309 9545234 Q99344 P29055 UBA3 SUA7 0.21 11283351 Q99344 Q99344 UBA3 UBA3 0.155 11805826 Q99344 Q12524 UBA3 PCD1 0.236 11283351 Q99344 P32589 UBA3 SSE1 0.126 19536198 Q9SYM2 Q99344 Q9SYM2 UBA3 0.033 18796637 Q99344 Q07807 UBA3 PUF3 0.126 26493364